Friedemann Weber

Institute for Virology, Philipps-University Marburg

Affiliated withPhilipps-University Marburg

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2014

Other Publications

Article	Year
Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon. Journal of virology\| PubMed ID: 12133999	2002
Antigenic drift, antigenic shift and interferon antagonists: how bunyaviruses counteract the immune system. Virus research\| PubMed ID: 12297332	2002
Novel gene product of Thogoto virus segment 6 codes for an interferon antagonist. Journal of virology\| PubMed ID: 12552016	2003
Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs. Journal of virology\| PubMed ID: 12692253	2003
Functional L polymerase of La Crosse virus allows in vivo reconstitution of recombinant nucleocapsids. The Journal of general virology\| PubMed ID: 12692286	2003
Bunyamwera virus nonstructural protein NSs counteracts interferon regulatory factor 3-mediated induction of early cell death. Journal of virology\| PubMed ID: 12829839	2003
Viral evasion of the interferon system: old viruses, new tricks. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 12856333	2003
Inhibition of Dugbe nairovirus replication by human MxA protein. Virus research\| PubMed ID: 14687945	2004
The antiviral effect of interferon-beta against SARS-coronavirus is not mediated by MxA protein. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 15135736	2004
Inhibition of RNA polymerase II phosphorylation by a viral interferon antagonist. The Journal of biological chemistry\| PubMed ID: 15150262	2004
High-efficiency detection of severe acute respiratory syndrome virus genetic material. Journal of clinical microbiology\| PubMed ID: 15184466	2004
NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription. Journal of virology\| PubMed ID: 15331713	2004
Thogoto virus ML protein suppresses IRF3 function. Virology\| PubMed ID: 15582653	2005
Inverse interference: how viruses fight the interferon system. Viral immunology\| PubMed ID: 15671747	2004
Inhibition of Beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3. Journal of virology\| PubMed ID: 15681410	2005
Efficient cDNA-based rescue of La Crosse bunyaviruses expressing or lacking the nonstructural protein NSs. Journal of virology\| PubMed ID: 16051834	2005
Activation of innate defense against a paramyxovirus is mediated by RIG-I and TLR7 and TLR8 in a cell-type-specific manner. Journal of virology\| PubMed ID: 16188996	2005
The interferon response circuit: induction and suppression by pathogenic viruses. Virology\| PubMed ID: 16364743	2006
A target on the move: innate and adaptive immune escape strategies of hepatitis C virus. Antiviral research\| PubMed ID: 16413618	2006
Induction of interferon synthesis by the PKR-inhibitory VA RNAs of adenoviruses. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 16426142	2006
Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence. Journal of virology\| PubMed ID: 16501110	2006
Inhibition of cytokine gene expression and induction of chemokine genes in non-lymphatic cells infected with SARS coronavirus. Virology journal\| PubMed ID: 16571117	2006
Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses. Journal of virology\| PubMed ID: 16641297	2006
Neurons produce type I interferon during viral encephalitis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16682623	2006
Interaction of severe acute respiratory syndrome-associated coronavirus with dendritic cells. The Journal of general virology\| PubMed ID: 16760397	2006
Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon. Blood\| PubMed ID: 16985170	2007
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science (New York, N.Y.)\| PubMed ID: 17038589	2006
The intracellular sites of early replication and budding of SARS-coronavirus. Virology\| PubMed ID: 17210170	2007
Viral suppression of the interferon system. Biochimie\| PubMed ID: 17336442	2007
La Crosse bunyavirus nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts. Journal of virology\| PubMed ID: 17344298	2007
Interferon, Mx, and viral countermeasures. Cytokine & growth factor reviews\| PubMed ID: 17683972	2007
Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines. PLoS pathogens\| PubMed ID: 17696607	2007
Tula and Puumala hantavirus NSs ORFs are functional and the products inhibit activation of the interferon-beta promoter. Journal of medical virology\| PubMed ID: 17705180	2007
Interaction of hepatitis C virus with the type I interferon system. World journal of gastroenterology : WJG\| PubMed ID: 17828812	2007
Interferon and cytokine responses to SARS-coronavirus infection. Cytokine & growth factor reviews\| PubMed ID: 18321765	2008
Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction. PloS one\| PubMed ID: 18446221	2008
Crimean-Congo hemorrhagic fever virus delays activation of the innate immune response. Journal of medical virology\| PubMed ID: 18551619	2008
T7 RNA polymerase-dependent and -independent systems for cDNA-based rescue of Rift Valley fever virus. The Journal of general virology\| PubMed ID: 18753225	2008
The interferon antagonist ML protein of thogoto virus targets general transcription factor IIB. Journal of virology\| PubMed ID: 18768974	2008
Interferon and cytokine responses to Crimean Congo hemorrhagic fever virus; an emerging and neglected viral zonoosis. Cytokine & growth factor reviews\| PubMed ID: 19027345	2008
Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity. Journal of virology\| PubMed ID: 19109397	2009
Efficient production of Rift Valley fever virus-like particles: The antiviral protein MxA can inhibit primary transcription of bunyaviruses. Virology\| PubMed ID: 19155037	2009
Vaccination with virus-like particles protects mice from lethal infection of Rift Valley Fever Virus. Virology\| PubMed ID: 19157482	2009
Electron cryo-microscopy and single-particle averaging of Rift Valley fever virus: evidence for GN-GC glycoprotein heterodimers. Journal of virology\| PubMed ID: 19193794	2009
NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase. Journal of virology\| PubMed ID: 19211744	2009
Interferon priming enables cells to partially overturn the SARS coronavirus-induced block in innate immune activation. The Journal of general virology\| PubMed ID: 19625461	2009
Thogoto virus ML protein is a potent inhibitor of the interferon regulatory factor-7 transcription factor. The Journal of general virology\| PubMed ID: 19812269	2010
Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63. Journal of virology\| PubMed ID: 19864379	2010
Species-independent bioassay for sensitive quantification of antiviral type I interferons. Virology journal\| PubMed ID: 20187932	2010
Molecular biology of rift valley Fever virus. The open virology journal\| PubMed ID: 20517489	2010
La Crosse virus (LACV) Gc fusion peptide mutants have impaired growth and fusion phenotypes, but remain neurotoxic. Virology\| PubMed ID: 20553924	2010
Tick-borne encephalitis virus delays interferon induction and hides its double-stranded RNA in intracellular membrane vesicles. Journal of virology\| PubMed ID: 20554782	2010
Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity. Journal of virology\| PubMed ID: 20844035	2010
Virus-like particles expressing the nucleocapsid gene as an efficient vaccine against Rift Valley fever virus. Vector borne and zoonotic diseases (Larchmont, N.Y.)\| PubMed ID: 20854024	2010
Toscana virus induces interferon although its NSs protein reveals antagonistic activity. The Journal of general virology\| PubMed ID: 20861320	2011
Bunyaviridae RNA polymerases (L-protein) have an N-terminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription. PLoS pathogens\| PubMed ID: 20862319	2010
Interferon antagonist NSs of La Crosse virus triggers a DNA damage response-like degradation of transcribing RNA polymerase II. The Journal of biological chemistry\| PubMed ID: 21118815	2011
Interferon interplay helps tissue cells to cope with SARS-coronavirus infection. Virulence\| PubMed ID: 21178452	2010
Old World hantaviruses do not produce detectable amounts of dsRNA in infected cells and the 5' termini of their genomic RNAs are monophosphorylated. The Journal of general virology\| PubMed ID: 21289157	2011
The ADP-ribose-1''-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses. The Journal of general virology\| PubMed ID: 21525212	2011
Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines. PLoS pathogens\| PubMed ID: 21552323	2011
Hiding from intracellular pattern recognition receptors, a passive strategy of flavivirus immune evasion. Virulence\| PubMed ID: 21555916	2011
IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA. Nature immunology\| PubMed ID: 21642987	2011
Bunyaviruses and the type I interferon system. Viruses\| PubMed ID: 21994579	2009
The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors. PLoS pathogens\| PubMed ID: 22046132	2011
Induction of DNA damage signaling upon Rift Valley fever virus infection results in cell cycle arrest and increased viral replication. The Journal of biological chemistry\| PubMed ID: 22223653	2012
Regulatory, biosafety and safety challenges for novel cells as substrates for human vaccines. Vaccine\| PubMed ID: 22342707	2012
Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination. PloS one\| PubMed ID: 22412934	2012
Viral immune modulators perturb the human molecular network by common and unique strategies. Nature\| PubMed ID: 22810585	2012
Structure of Crimean-Congo hemorrhagic fever virus nucleoprotein: superhelical homo-oligomers and the role of caspase-3 cleavage. Journal of virology\| PubMed ID: 22951837	2012
Severe fever with thrombocytopenia virus glycoproteins are targeted by neutralizing antibodies and can use DC-SIGN as a receptor for pH-dependent entry into human and animal cell lines. Journal of virology\| PubMed ID: 23388721	2013
Human cell tropism and innate immune system interactions of human respiratory coronavirus EMC compared to those of severe acute respiratory syndrome coronavirus. Journal of virology\| PubMed ID: 23449793	2013
Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling. Cell host & microbe\| PubMed ID: 23498958	2013
Structural basis for encapsidation of genomic RNA by La Crosse Orthobunyavirus nucleoprotein. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23589854	2013
Systems to establish bunyavirus genome replication in the absence of transcription. Journal of virology\| PubMed ID: 23698297	2013
IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-α secretion and LPS-induced endotoxin shock. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24014876	2013
Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist. Journal of virology\| PubMed ID: 24027320	2013
Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity. Cellular microbiology\| PubMed ID: 24245804	2014
Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH. Journal of virology\| PubMed ID: 24403578	2014
Structural insights into RNA encapsidation and helical assembly of the Toscana virus nucleoprotein. Nucleic acids research\| PubMed ID: 24688060	2014
RIG-I-like receptors and negative-strand RNA viruses: RLRly bird catches some worms. Cytokine & growth factor reviews\| PubMed ID: 24894317	2014
Segmented negative-strand RNA viruses and RIG-I: divide (your genome) and rule. Current opinion in microbiology\| PubMed ID: 24930021	2014