Francesco S. Pavone

LENS - European Laboratory for Non-linear Spectroscopy, University of Florence

Affiliated withUniversity of Florence National Institute of Optics-National Research Council, Italy International Center of Computational Neurophotonics

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 10	2014
Publication title Cited by 6	2021
Publication title Cited by 5	2024

Other Publications

Article	Year
Positioning and elongation of the fission yeast spindle by microtubule-based pushing. Current biology : CB\| PubMed ID: 15242615	2004
Optical micromanipulations inside yeast cells. Applied optics\| PubMed ID: 15835347	2005
Combined intracellular three-dimensional imaging and selective nanosurgery by a nonlinear microscope. Journal of biomedical optics\| PubMed ID: 15847583	2005
Nuclear and division-plane positioning revealed by optical micromanipulation. Current biology : CB\| PubMed ID: 16005294	2005
Real-time observation of DNA looping dynamics of Type IIE restriction enzymes NaeI and NarI. Nucleic acids research\| PubMed ID: 16407332	2006
Hypergravity speeds up the development of T-lymphocyte motility. European biophysics journal : EBJ\| PubMed ID: 16496137	2006
Stepwise bending of DNA by a single TATA-box binding protein. Biophysical journal\| PubMed ID: 16500964	2006
In vivo multiphoton nanosurgery on cortical neurons. Journal of biomedical optics\| PubMed ID: 17994859	2007
Optical recording of electrical activity in intact neuronal networks with random access second-harmonic generation microscopy. Optics express\| PubMed ID: 18795028	2008
Photothermally-induced disordered patterns of corneal collagen revealed by SHG imaging. Optics express\| PubMed ID: 19293918	2009
A voyage from the nano world to the macro through the micro. Journal of biophotonics\| PubMed ID: 19343647	2008
Scoring of collagen organization in healthy and diseased human dermis by multiphoton microscopy. Journal of biophotonics\| PubMed ID: 19771581	2010
Tetramer opening in LacI-mediated DNA looping. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19805348	2009
Time- and Spectral-resolved two-photon imaging of healthy bladder mucosa and carcinoma in situ. Optics express\| PubMed ID: 20389394	2010
Multi-photon nanosurgery in live brain. Frontiers in neuroenergetics\| PubMed ID: 20725602	2010
Single molecule tracking analysis reveals that the surface mobility of amyloid oligomers is driven by their conformational structure. Journal of the American Chemical Society\| PubMed ID: 21721557	2011
Action potential propagation in transverse-axial tubular system is impaired in heart failure. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22451916	2012
Protein conformation and molecular order probed by second-harmonic-generation microscopy. Journal of biomedical optics\| PubMed ID: 22734730	2012
Thermal transitions of fibrillar collagen unveiled by second-harmonic generation microscopy of corneal stroma. Biophysical journal\| PubMed ID: 22995490	2012
Palette of fluorinated voltage-sensitive hemicyanine dyes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23169660	2012
IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor. Molecular and cellular biology\| PubMed ID: 23382078	2013
Two-photon microscopy imaging of thy1GFP-M transgenic mice: a novel animal model to investigate brain dendritic cell subsets in vivo. PloS one\| PubMed ID: 23409142	2013
Optical Methods to Study Protein-DNA Interactions in Vitro and in Living Cells at the Single-Molecule Level. International journal of molecular sciences\| PubMed ID: 23429188	2013
Spectral morphological analysis of skin lesions with a polarization multispectral dermoscope. Optics express\| PubMed ID: 23482017	2013
Partitioning and confinement of GM1 ganglioside induced by amyloid aggregates. FEBS letters\| PubMed ID: 23523632	2013
In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebellar cortex. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23754371	2013
Multiphoton morpho-functional imaging of healthy colon mucosa, adenomatous polyp and adenocarcinoma. Biomedical optics express\| PubMed ID: 23847743	2013
Interrogating biology with force: single molecule high-resolution measurements with optical tweezers. Biophysical journal\| PubMed ID: 24047980	2013
In-vivo imaging of psoriatic lesions with polarization multispectral dermoscopy and multiphoton microscopy. Biomedical optics express\| PubMed ID: 25071974	2014
Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25288764	2014
Functional cardiac imaging by random access microscopy. Frontiers in physiology\| PubMed ID: 25368580	2014
Towards a comprehensive understanding of brain machinery by correlative microscopy. Journal of biomedical optics\| PubMed ID: 25749101	2015
Quantitative neuroanatomy of all Purkinje cells with light sheet microscopy and high-throughput image analysis. Frontiers in neuroanatomy\| PubMed ID: 26074783	2015
Comprehensive optical and data management infrastructure for high-throughput light-sheet microscopy of whole mouse brains. Neurophotonics\| PubMed ID: 26158018	2015
Multi-Modal Optical Imaging of the Cerebellum in Animals. Cerebellum (London, England)\| PubMed ID: 26476852	2016
Label-free near-infrared reflectance microscopy as a complimentary tool for two-photon fluorescence brain imaging. Biomedical optics express\| PubMed ID: 26601011	2015
Observation of an improved healing process in superficial skin wounds after irradiation with a blue-LED haemostatic device. Journal of biophotonics\| PubMed ID: 26756549	2016
Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin. Journal of cellular and molecular medicine\| PubMed ID: 26990223	2016
T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure. International journal of molecular sciences\| PubMed ID: 27598150	2016
Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation. Scientific reports\| PubMed ID: 27748433	2016
Roadmap on neurophotonics. Journal of optics (2010)\| PubMed ID: 28386392	2016
Direct imaging of APP proteolysis in living cells. PeerJ\| PubMed ID: 28413720	2017
Optogenetics gets to the heart: A guiding light beyond defibrillation. Progress in biophysics and molecular biology\| PubMed ID: 28506694	2017
Probing Collagen Organization: Practical Guide for Second-Harmonic Generation (SHG) Imaging. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 28836217	2017
Data integration through brain atlasing: Human Brain Project tools and strategies. European psychiatry : the journal of the Association of European Psychiatrists\| PubMed ID: 29519589	2018
Improved label-free diagnostics and pathological assessment of atherosclerotic plaques through nonlinear microscopy. Journal of biophotonics\| PubMed ID: 29931805	2018
Whole-Brain Vasculature Reconstruction at the Single Capillary Level. Scientific reports\| PubMed ID: 30135559	2018
Bessel Beam Illumination Reduces Random and Systematic Errors in Quantitative Functional Studies Using Light-Sheet Microscopy. Frontiers in cellular neuroscience\| PubMed ID: 30294262	2018
Axial Tubule Junctions Activate Atrial Ca Release Across Species. Frontiers in physiology\| PubMed ID: 30349482	2018
Interplay Between Sub-Cellular Alterations of Calcium Release and T-Tubular Defects in Cardiac Diseases. Frontiers in physiology\| PubMed ID: 30410446	2018
High-Fidelity Imaging in Brain-Wide Structural Studies Using Light-Sheet Microscopy. eNeuro\| PubMed ID: 30627630	2018
Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction. Circulation research\| PubMed ID: 30732554	2019
Corrigendum: Bessel Beam Illumination Reduces Random and Systematic Errors in Quantitative Functional Studies Using Light-Sheet Microscopy. Frontiers in cellular neuroscience\| PubMed ID: 30853897	2019
Cardiac sympathetic innervation network shapes the myocardium by locally controlling cardiomyocyte size through the cellular proteolytic machinery. The Journal of physiology\| PubMed ID: 31116413	2019
A Software Architecture to Mimic a Ventricular Tachycardia in Intact Murine Hearts by Means of an All-Optical Platform. Methods and protocols\| PubMed ID: 31164591	2019
Large Scale Double-Path Illumination System with Split Field of View for the All-Optical Study of Inter-and Intra-Hemispheric Functional Connectivity on Mice. Methods and protocols\| PubMed ID: 31164593	2019
Multispectral Depth-Resolved Fluorescence Lifetime Spectroscopy Using SPAD Array Detectors and Fiber Probes. Sensors (Basel, Switzerland)\| PubMed ID: 31200569	2019
Publisher Correction: Whole-Brain Vasculature Reconstruction at the Single Capillary Level. Scientific reports\| PubMed ID: 31201354	2019
Label-free grading and staging of urothelial carcinoma through multimodal fibre-probe spectroscopy. Journal of biophotonics\| PubMed ID: 31343832	2019
Dual-beam confocal light-sheet microscopy via flexible acousto-optic deflector. Journal of biomedical optics\| PubMed ID: 31674164	2019
Real-time fiber-based fluorescence lifetime imaging with synchronous external illumination: A new path for clinical translation. Journal of biophotonics\| PubMed ID: 31742905	2020
Blue LED light modulates inflammatory infiltrate and improves the healing of superficial wounds. Photodermatology, photoimmunology & photomedicine\| PubMed ID: 31769893	2020
Real-time multispectral fluorescence lifetime imaging using Single Photon Avalanche Diode arrays. Scientific reports\| PubMed ID: 32415224	2020
Experimental and Computational Study on Motor Control and Recovery After Stroke: Toward a Constructive Loop Between Experimental and Virtual Embodied Neuroscience. Frontiers in systems neuroscience\| PubMed ID: 32733210	2020
Dissecting Neuronal Activation on a Brain-Wide Scale With Immediate Early Genes. Frontiers in neuroscience\| PubMed ID: 33192255	2020
Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study. Analytical chemistry\| PubMed ID: 33225709	2020
detection of murine glioblastoma through Raman and reflectance fiber-probe spectroscopies. Neurophotonics\| PubMed ID: 33274251	2020
Supervised learning methods for the recognition of melanoma cell lines through the analysis of their Raman spectra. Journal of biophotonics\| PubMed ID: 33305912	2021
Photobiomodulation of Human Fibroblasts and Keratinocytes with Blue Light: Implications in Wound Healing. Biomedicines\| PubMed ID: 33466557	2021
Monitoring Changes in Biochemical and Biomechanical Properties of Collagenous Tissues Using Label-Free and Nondestructive Optical Imaging Techniques. Analytical chemistry\| PubMed ID: 33596051	2021
Removing striping artifacts in light-sheet fluorescence microscopy: a review. Progress in biophysics and molecular biology\| PubMed ID: 34274370	2021
Optical clearing in cardiac imaging: A comparative study. Progress in biophysics and molecular biology\| PubMed ID: 34358555	2021
Analysis on the Characterization of Multiphoton Microscopy Images for Malignant Neoplastic Colon Lesion Detection under Deep Learning Methods. Journal of pathology informatics\| PubMed ID: 34447607	2021
Fast Optical Investigation of Cardiac Electrophysiology by Parallel Detection in Multiwell Plates. Frontiers in physiology\| PubMed ID: 34539428	2021
Lac repressor hinge flexibility and DNA looping: single molecule kinetics by tethered particle motion. Nucleic acids research\| PubMed ID: 16835309	2006
Optical methods in the study of protein-protein interactions. Advances in experimental medicine and biology\| PubMed ID: 20549938	2010
Non-linear fluorescence lifetime imaging of biological tissues. Analytical and bioanalytical chemistry\| PubMed ID: 21455652	2011
Ultrafast force-clamp spectroscopy of single molecules reveals load dependence of myosin working stroke. Nature methods\| PubMed ID: 22941363	2012
Correlative two-photon and light sheet microscopy. Methods (San Diego, Calif.)\| PubMed ID: 23806642	2013
Decoupling polarization of the Golgi apparatus and GM1 in the plasma membrane. PloS one\| PubMed ID: 24312472	2013
The theory of pattern formation on directed networks. Nature communications\| PubMed ID: 25077521	2014
Clinical nonlinear laser imaging of human skin: a review. BioMed research international\| PubMed ID: 25250337	2014
Multispot multiphoton Ca²⁺ imaging in acute myocardial slices. Journal of biomedical optics\| PubMed ID: 25517401	2015
A versatile clearing agent for multi-modal brain imaging. Scientific reports\| PubMed ID: 25950610	2015
3D tracking of single nanoparticles and quantum dots in living cells by out-of-focus imaging with diffraction pattern recognition. Scientific reports\| PubMed ID: 26526410	2015
Three-dimensional mapping of the orientation of collagen corneal lamellae in healthy and keratoconic human corneas using SHG microscopy. Journal of biophotonics\| PubMed ID: 27472438	2017
Multimodal fiber-probe spectroscopy allows detecting epileptogenic focal cortical dysplasia in children. Journal of biophotonics\| PubMed ID: 28067998	2017
Confocal multispot microscope for fast and deep imaging in semicleared tissues. Journal of biomedical optics\| PubMed ID: 29460510	2018
Sliding of a single lac repressor protein along DNA is tuned by DNA sequence and molecular switching. Nucleic acids research\| PubMed ID: 29584872	2018
PLANT: A Method for Detecting Changes of Slope in Noisy Trajectories. Biophysical journal\| PubMed ID: 29742398	2018
Three-Dimensional Tracking of Quantum Dot-Conjugated Molecules in Living Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29956248	2018
Dissecting myosin-5B mechanosensitivity and calcium regulation at the single molecule level. Nature communications\| PubMed ID: 30030431	2018
Astrocytic endfeet re-cover blood vessels after removal by laser ablation. Scientific reports\| PubMed ID: 30718555	2019
Flexible Multi-Beam Light-Sheet Fluorescence Microscope for Live Imaging Without Striping Artifacts. Frontiers in neuroanatomy\| PubMed ID: 30800060	2019
Morpho-mechanics of human collagen superstructures revealed by all-optical correlative micro-spectroscopies. Communications biology\| PubMed ID: 30937399	2019
Tailored Sample Mounting for Light-Sheet Fluorescence Microscopy of Clarified Specimens by Polydimethylsiloxane Casting. Frontiers in neuroanatomy\| PubMed ID: 30971902	2019
Data on the target search by a single protein on DNA measured with ultrafast force-clamp spectroscopy. Data in brief\| PubMed ID: 31193354	2019
Myosin V fluorescence imaging dataset for single-molecule localization and tracking. Data in brief\| PubMed ID: 31194150	2019
Ultra-fast force-clamp spectroscopy data on the interaction between skeletal muscle myosin and actin. Data in brief\| PubMed ID: 31223637	2019
Custom Multiphoton/Raman Microscopy Setup for Imaging and Characterization of Biological Samples. Methods and protocols\| PubMed ID: 31226732	2019
A protocol for single molecule imaging and tracking of processive myosin motors. MethodsX\| PubMed ID: 31508322	2019
Combined Rehabilitation Promotes the Recovery of Structural and Functional Features of Healthy Neuronal Networks after Stroke. Cell reports\| PubMed ID: 31553915	2019
In-vivo and ex-vivo optical clearing methods for biological tissues: review. Biomedical optics express\| PubMed ID: 31646045	2019
Pre-diagnosing and managing patients with GM1 gangliosidosis and related disorders by the evaluation of GM1 ganglioside content. Scientific reports\| PubMed ID: 31776384	2019
Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy: A Translational Study. JACC. Basic to translational science\| PubMed ID: 31998849	2019
Fiber-cap biosensors for SERS analysis of liquid samples. Journal of materials chemistry. B\| PubMed ID: 32011615	2020
Analysis and Model of Cortical Slow Waves Acquired with Optical Techniques. Methods and protocols\| PubMed ID: 32023996	2020
Collagen ultrastructural symmetry and its malignant alterations in human breast cancer revealed by polarization-resolved second-harmonic generation microscopy. Journal of biophotonics\| PubMed ID: 32472568	2020
Fast multi-directional DSLM for confocal detection without striping artifacts. Biomedical optics express\| PubMed ID: 32637245	2020
1-benzyl-1,4-diazepane reduces the efflux of resistance-nodulation-cell division pumps in . Future microbiology\| PubMed ID: 32840130	2020
3D imaging and morphometry of the heart capillary system in spontaneously hypertensive rats and normotensive controls. Scientific reports\| PubMed ID: 32868776	2020
Effects of excitation light polarization on fluorescence emission in two-photon light-sheet microscopy. Biomedical optics express\| PubMed ID: 32923069	2020
Colored visual stimuli evoke spectrally tuned neuronal responses across the central nervous system of zebrafish larvae. BMC biology\| PubMed ID: 33243249	2020
Experimental Study on Blue Light Interaction with Human Keloid-Derived Fibroblasts. Biomedicines\| PubMed ID: 33291338	2020
The feasibility of multimodal fiber optic spectroscopy analysis in bladder cancer detection, grading, and staging. Urologia\| PubMed ID: 33789562	2021
Gold Nanostars Bioconjugation for Selective Targeting and SERS Detection of Biofluids. Nanomaterials (Basel, Switzerland)\| PubMed ID: 33800443	2021
Reconstruction scheme for excitatory and inhibitory dynamics with quenched disorder: application to zebrafish imaging. Journal of computational neuroscience\| PubMed ID: 33826050	2021
Autofluorescence enhancement for label-free imaging of myelinated fibers in mammalian brains. Scientific reports\| PubMed ID: 33850168	2021
Carbon Nanotubes/Regenerated Silk Composite as a Three-Dimensional Printable Bio-Adhesive Ink with Self-Powering Properties. ACS applied materials & interfaces\| PubMed ID: 33934601	2021
Cortical propagation tracks functional recovery after stroke. PLoS computational biology\| PubMed ID: 33999967	2021
Exploring the human cerebral cortex using confocal microscopy. Progress in biophysics and molecular biology\| PubMed ID: 34536443	2021
Distributed and Localized Dynamics Emerge in the Mouse Neocortex during Reach-to-Grasp Behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 34732524	2022
Characterization of substituted piperazines able to reverse MDR in Escherichia coli strains overexpressing resistance-nodulation-cell division (RND) efflux pumps. The Journal of antimicrobial chemotherapy\| PubMed ID: 34747445	2022
Combining Optogenetic Stimulation and Motor Training Improves Functional Recovery and Perilesional Cortical Activity. Neurorehabilitation and neural repair\| PubMed ID: 34761714	2022
Comparison of Different Tissue Clearing Methods for Three-Dimensional Reconstruction of Human Brain Cellular Anatomy Using Advanced Imaging Techniques. Frontiers in neuroanatomy\| PubMed ID: 34867215	2021
Quantification of Myocyte Disarray in Human Cardiac Tissue. Frontiers in physiology\| PubMed ID: 34867455	2021
Efficient Inactivation of SARS-CoV-2 and Other RNA or DNA Viruses with Blue LED Light. Pathogens (Basel, Switzerland)\| PubMed ID: 34959545	2021
Power-effective scanning with AODs for 3D optogenetic applications. Journal of biophotonics\| PubMed ID: 35000289	2022
Structural and Biochemical Changes in Pericardium upon Genipin Cross-Linking Investigated Using Nondestructive and Label-Free Imaging Techniques. Analytical chemistry\| PubMed ID: 35015512	2022
Novel Pixelwise Co-Registered Hematoxylin-Eosin and Multiphoton Microscopy Image Dataset for Human Colon Lesion Diagnosis. Journal of pathology informatics\| PubMed ID: 35223136	2022
Fast whole-brain imaging of seizures in zebrafish larvae by two-photon light-sheet microscopy. Biomedical optics express\| PubMed ID: 35414999	2022
Neurophotonic tools for microscopic measurements and manipulation: status report. Neurophotonics\| PubMed ID: 35493335	2022
3D molecular phenotyping of cleared human brain tissues with light-sheet fluorescence microscopy. Communications biology\| PubMed ID: 35551498	2022
Design, synthesis and evaluation of RGD peptidomimetic - Gold nanostar conjugates as M21 cell adhesion inhibitors. Bioorganic chemistry\| PubMed ID: 35598570	2022
Tracking the Effect of Therapy With Single-Trial Based Classification After Stroke. Frontiers in systems neuroscience\| PubMed ID: 35602972	2022
Multimodal Characterization of Seizures in Zebrafish Larvae. Biomedicines\| PubMed ID: 35625689	2022
Design and Synthesis of Novel Raman Reporters for Bioorthogonal SERS Nanoprobes Engineering. International journal of molecular sciences\| PubMed ID: 35628383	2022
Latency correction in sparse neuronal spike trains. Journal of neuroscience methods\| PubMed ID: 36075286	2022
Fluorescent Labeling of Lignin Nanocapsules with Fluorol Yellow 088. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 36152265	2023
Blue-LED-Light Photobiomodulation of Inflammatory Responses and New Tissue Formation in Mouse-Skin Wounds. Life (Basel, Switzerland)\| PubMed ID: 36295000	2022
Large-scale all-optical dissection of motor cortex connectivity shows a segregated organization of mouse forelimb representations. Cell reports\| PubMed ID: 36351410	2022
Particle Localization Using Local Gradients and Its Application to Nanometer Stabilization of a Microscope. ACS nano\| PubMed ID: 36383436	2022
Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 36421008	2022
KHz-rate volumetric voltage imaging of the whole Zebrafish heart. Biophysical reports\| PubMed ID: 36425080	2022
Photothrombotic Middle Cerebral Artery Occlusion in Mice: A Novel Model of Ischemic Stroke. eNeuro\| PubMed ID: 36650068	2023
In Vivo Imaging of the Structural Plasticity of Cortical Neurons After Stroke. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 36715929	2023
Fiber enhancement and 3D orientation analysis in label-free two-photon fluorescence microscopy. Scientific reports\| PubMed ID: 36914673	2023
Dysplasia and tumor discrimination in brain tissues by combined fluorescence, Raman, and diffuse reflectance spectroscopies. Biomedical optics express\| PubMed ID: 36950232	2023
A Guide to Perform 3D Histology of Biological Tissues with Fluorescence Microscopy. International journal of molecular sciences\| PubMed ID: 37047724	2023
APP and Bace1: Differential effect of cholesterol enrichment on processing and plasma membrane mobility. iScience\| PubMed ID: 37128606	2023
Fiber-Based SERS-Fluidic Polymeric Platforms for Improved Optical Analysis of Liquids. Bioengineering (Basel, Switzerland)\| PubMed ID: 37370607	2023
Imaging Approaches to Investigate Pathophysiological Mechanisms of Brain Disease in Zebrafish. International journal of molecular sciences\| PubMed ID: 37372981	2023
Brain-wide neuron quantification toolkit reveals strong sexual dimorphism in the evolution of fear memory. Cell reports\| PubMed ID: 37516963	2023
Nogo-A antibody delivery through the olfactory mucosa mitigates experimental autoimmune encephalomyelitis in the mouse CNS. Cell death discovery\| PubMed ID: 37558696	2023
Multilayered Bioorthogonal SERS Nanoprobes Selectively Aggregating in Human Fluids: A Smart Optical Assay for β-Amyloid Peptide Quantification. ACS sensors\| PubMed ID: 37758234	2023
A cellular resolution atlas of Broca's area. Science advances\| PubMed ID: 37824623	2023
Segmentation of supragranular and infragranular layers in ultra-high resolution 7T MRI of the human cerebral cortex. bioRxiv : the preprint server for biology\| PubMed ID: 38106176	2023
Microplastics reach the brain and interfere with honey bee cognition. The Science of the total environment\| PubMed ID: 38128669	2024
A modular and adaptable analysis pipeline to compare slow cerebral rhythms across heterogeneous datasets. Cell reports methods\| PubMed ID: 38183979	2024