Andrew Tsourkas

Department of Bioengineering, University of Pennsylvania

Affiliated withUniversity of Pennsylvania

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2014

Other Publications

Article	Year
Structure-function relationships of shared-stem and conventional molecular beacons. Nucleic acids research\| PubMed ID: 12364599	2002
Hybridization of 2'-O-methyl and 2'-deoxy molecular beacons to RNA and DNA targets. Nucleic acids research\| PubMed ID: 12466541	2002
Hybridization kinetics and thermodynamics of molecular beacons. Nucleic acids research\| PubMed ID: 12582252	2003
Hybridization of 2'-O-methyl and 2'-deoxy molecular beacons to RNA and DNA targets. Nucleic acids research\| PubMed ID: 12669716	2003
Spectroscopic features of dual fluorescence/luminescence resonance energy-transfer molecular beacons. Analytical chemistry\| PubMed ID: 14572032	2003
Dual FRET molecular beacons for mRNA detection in living cells. Nucleic acids research\| PubMed ID: 15084672	2004
Magnetic relaxation switch immunosensors detect enantiomeric impurities. Angewandte Chemie (International ed. in English)\| PubMed ID: 15114571	2004
Shedding light on health and disease using molecular beacons. Briefings in functional genomics & proteomics\| PubMed ID: 15239884	2003
Detection of vascular adhesion molecule-1 expression using a novel multimodal nanoparticle. Circulation research\| PubMed ID: 15653572	2005
Detection of peroxidase/H2O2-mediated oxidation with enhanced yellow fluorescent protein. Analytical chemistry\| PubMed ID: 15859603	2005
In vivo imaging of activated endothelium using an anti-VCAM-1 magnetooptical probe. Bioconjugate chemistry\| PubMed ID: 15898724	2005
Superparamagnetic iron oxide nanoparticle probes for molecular imaging. Annals of biomedical engineering\| PubMed ID: 16496086	2006
Engineering nanostructured probes for sensitive intracellular gene detection. Mechanics & chemistry of biosystems : MCB\| PubMed ID: 16783944	2004
Suicide gene delivery by calcium phosphate nanoparticles: a novel method of targeted therapy for gastric cancer. Cancer biology & therapy\| PubMed ID: 17224632	2006
Avoiding false-positive signals with nuclease-vulnerable molecular beacons in single living cells. Nucleic acids research\| PubMed ID: 17702767	2007
Iron chelator-based amplification strategy for improved targeting of transferrin receptor with SPIO. Cancer biology & therapy\| PubMed ID: 18367876	2008
Efficient cytosolic delivery of molecular beacon conjugates and flow cytometric analysis of target RNA. Nucleic acids research\| PubMed ID: 18503086	2008
Size, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cells. Biomaterials\| PubMed ID: 18533252	2008
Paramagnetic porous polymersomes. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 18570445	2008
Assessing the sensitivity of commercially available fluorophores to the intracellular environment. Analytical chemistry\| PubMed ID: 18700780	2008
In vivo imaging of cancer biomarkers using activatable molecular probes. Cancer biomarkers : section A of Disease markers\| PubMed ID: 19126958	2008
Fluorescent probes for live-cell RNA detection. Annual review of biomedical engineering\| PubMed ID: 19400712	2009
Imaging individual microRNAs in single mammalian cells in situ. Nucleic acids research\| PubMed ID: 19515934	2009
Comparative analysis of nanoparticle-antibody conjugations: carbodiimide versus click chemistry. Molecular imaging\| PubMed ID: 19728976	2009
Sub-cellular trafficking and functionality of 2'-O-methyl and 2'-O-methyl-phosphorothioate molecular beacons. Nucleic acids research\| PubMed ID: 19820111	2009
Two-photon imaging of multicellular tumor spheroids: a novel method for evaluating the efficacy of CDC25 phosphatase inhibitors. Cancer biology & therapy\| PubMed ID: 19855193	2009
Gadolinium-conjugated dendrimer nanoclusters as a tumor-targeted T1 magnetic resonance imaging contrast agent. Angewandte Chemie (International ed. in English)\| PubMed ID: 19967688	2010
Imaging circulating cells and lymphoid tissues with iron oxide nanoparticles. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program\| PubMed ID: 20008258	2009
In vivo, multimodal imaging of B cell distribution and response to antibody immunotherapy in mice. PloS one\| PubMed ID: 20498725	2010
Ratiometric bimolecular beacons for the sensitive detection of RNA in single living cells. Nucleic acids research\| PubMed ID: 20507905	2010
Examination of folate-targeted liposomes with encapsulated poly(2-propylacrylic acid) as a pH-responsive nanoplatform for cytosolic drug delivery. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 20564486	2010
An intein-mediated site-specific click conjugation strategy for improved tumor targeting of nanoparticle systems. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 20925038	2010
Quantification of miRNA abundance in single cells using locked nucleic acid-FISH and enzyme-labeled fluorescence. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21153374	2011
Delivery of molecular beacons for live-cell imaging and analysis of RNA. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21431740	2011
Superparamagnetic iron oxide-enhanced magnetic resonance imaging of neuroinflammation in a rat model of radicular pain. Molecular imaging\| PubMed ID: 21496449	2011
Firefly luciferase and RLuc8 exhibit differential sensitivity to oxidative stress in apoptotic cells. PloS one\| PubMed ID: 21603648	2011
Improved tumor targeting of polymer-based nanovesicles using polymer-lipid blends. Bioconjugate chemistry\| PubMed ID: 21899335	2011
pH-titratable superparamagnetic iron oxide for improved nanoparticle accumulation in acidic tumor microenvironments. ACS nano\| PubMed ID: 22035454	2011
ICP-MS analysis of lanthanide-doped nanoparticles as a non-radiative, multiplex approach to quantify biodistribution and blood clearance. Biomaterials\| PubMed ID: 22100983	2012
Xanthine oxidase-generated hydrogen peroxide is a consequence, not a mediator of cell death. The FEBS journal\| PubMed ID: 22230240	2012
Effect of ligand density, receptor density, and nanoparticle size on cell targeting. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 22687896	2013
Emerging role of radiolabeled nanoparticles as an effective diagnostic technique. EJNMMI research\| PubMed ID: 22809406	2012
Improving nanoparticle delivery with anti-angiogenesis therapy. Nanomedicine (London, England)\| PubMed ID: 22846089	2012
Simultaneous quantification of tumor uptake for targeted and nontargeted liposomes and their encapsulated contents by ICPMS. Analytical chemistry\| PubMed ID: 22882145	2012
Synergizing radiation therapy with drug-loaded nanovectors. Nanomedicine (London, England)\| PubMed ID: 23019671	2012
Enhancing the cell uptake of nanoparticles within tumors. Nanomedicine (London, England)\| PubMed ID: 23019672	2012
Targeted and drug-loaded micelles. Nanomedicine (London, England)\| PubMed ID: 23019673	2012
Biodegradable polydisulfide dendrimer nanoclusters as MRI contrast agents. ACS nano\| PubMed ID: 23098069	2012
Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities. Science (New York, N.Y.)\| PubMed ID: 23161990	2012
Porous Polymersomes with Encapsulated Gd-labeled Dendrimers as Highly Efficient MRI Contrast Agents. Advanced functional materials\| PubMed ID: 23293575	2009
Gd-based macromolecules and nanoparticles as magnetic resonance contrast agents for molecular imaging. Current topics in medicinal chemistry\| PubMed ID: 23432004	2013
Selective targeting of brain tumors with gold nanoparticle-induced radiosensitization. PloS one\| PubMed ID: 23638079	2013
Quantitative assessment of ratiometric bimolecular beacons as a tool for imaging single engineered RNA transcripts and measuring gene expression in living cells. Nucleic acids research\| PubMed ID: 23814183	2013
Gd-labeled glycol chitosan as a pH-responsive magnetic resonance imaging agent for detecting acidic tumor microenvironments. Journal of medicinal chemistry\| PubMed ID: 24044414	2013
Sortase-tag expressed protein ligation: combining protein purification and site-specific bioconjugation into a single step. Analytical chemistry\| PubMed ID: 24111659	2013
Assessment of global cardiac uptake of radiolabeled iron oxide nanoparticles in apolipoprotein-E-deficient mice: implications for imaging cardiovascular inflammation. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 24297372	2014
Gold-loaded polymeric micelles for computed tomography-guided radiation therapy treatment and radiosensitization. ACS nano\| PubMed ID: 24377302	2014
Imaging the directed transport of single engineered RNA transcripts in real-time using ratiometric bimolecular beacons. PloS one\| PubMed ID: 24454933	2014
Stabilized porous liposomes with encapsulated Gd-labeled dextran as a highly efficient MRI contrast agent. Chemical communications (Cambridge, England)\| PubMed ID: 24457826	2014
Theranostic gold nanoparticles modified for durable systemic circulation effectively and safely enhance the radiation therapy of human sarcoma cells and tumors. Translational oncology\| PubMed ID: 24466375	2013
Facile Method for the Site-Specific, Covalent Attachment of Full-Length IgG onto Nanoparticles. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 24729432	2014
A Novel Chitosan-Hydrogel-Based Nanoparticle Delivery System for Local Inner Ear Application. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology\| PubMed ID: 24836592	2014
Exploring silver as a contrast agent for contrast-enhanced dual-energy x-ray breast imaging. The British journal of radiology\| PubMed ID: 24998157	2014
Quantitative Comparison of Tumor Delivery for Multiple Targeted Nanoparticles Simultaneously by Multiplex ICP-MS. Scientific reports\| PubMed ID: 25068300	2014