Louis Schofield

Division of Infection and Immunity, Walter and Eliza Hall Institute of Medical Research

Affiliated withWalter and Eliza Hall Institute of Medical Research University of Melbourne Walter and Eliza Hall Institute of Medical Research

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 18	2014

Other Publications

Article	Year
Genes for glycosylphosphatidylinositol toxin biosynthesis in Plasmodium falciparum. Infection and immunity\| PubMed ID: 12117963	2002
Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Nature\| PubMed ID: 12181569	2002
Regulation of murine cerebral malaria pathogenesis by CD1d-restricted NKT cells and the natural killer complex. Immunity\| PubMed ID: 12648456	2003
The lack of suppressor of cytokine signalling-1 (SOCS1) protects mice from the development of cerebral malaria caused by Plasmodium berghei ANKA. Parasite immunology\| PubMed ID: 12911518	2003
CD1d-restricted NKT cells contribute to malarial splenomegaly and enhance parasite-specific antibody responses. European journal of immunology\| PubMed ID: 12938235	2003
MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and Toll-like receptor 2 signaling. European journal of immunology\| PubMed ID: 14515266	2003
Regulation of immunity and pathogenesis in infectious diseases by CD1d-restricted NKT cells. International journal for parasitology\| PubMed ID: 14711586	2004
Transcriptional profiling reveals suppressed erythropoiesis, up-regulated glycolysis, and interferon-associated responses in murine malaria. The Journal of infectious diseases\| PubMed ID: 15031794	2004
The natural killer complex regulates severe malarial pathogenesis and influences acquired immune responses to Plasmodium berghei ANKA. Infection and immunity\| PubMed ID: 15784573	2005
Influence of glycosylphosphatidylinositol anchorage on the efficacy of DNA vaccines encoding Plasmodium yoelii merozoite surface protein 4/5. Vaccine\| PubMed ID: 15964480	2005
Immunological processes in malaria pathogenesis. Nature reviews. Immunology\| PubMed ID: 16138104	2005
Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum. The Journal of biological chemistry\| PubMed ID: 16203726	2005
Severe malarial anemia of low parasite burden in rodent models results from accelerated clearance of uninfected erythrocytes. Blood\| PubMed ID: 16210332	2006
Clinical immunity to malaria. Current molecular medicine\| PubMed ID: 16515511	2006
Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum. Molecular & cellular proteomics : MCP\| PubMed ID: 16603573	2006
Preferential invasion of reticulocytes during late-stage Plasmodium berghei infection accounts for reduced circulating reticulocyte levels. International journal for parasitology\| PubMed ID: 16979643	2006
Fatty acids from Plasmodium falciparum down-regulate the toxic activity of malaria glycosylphosphatidylinositols. Infection and immunity\| PubMed ID: 16988223	2006
CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis. Infection and immunity\| PubMed ID: 17325053	2007
Intravascular infiltrates and organ-specific inflammation in malaria pathogenesis. Immunology and cell biology\| PubMed ID: 17344907	2007
Rational approaches to developing an anti-disease vaccine against malaria. Microbes and infection / Institut Pasteur\| PubMed ID: 17434329	2007
NK cells stimulate recruitment of CXCR3+ T cells to the brain during Plasmodium berghei-mediated cerebral malaria. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17442962	2007
Murine cerebral malaria development is independent of toll-like receptor signaling. The American journal of pathology\| PubMed ID: 17456769	2007
Inhibition of dendritic cell maturation by malaria is dose dependent and does not require Plasmodium falciparum erythrocyte membrane protein 1. Infection and immunity\| PubMed ID: 17470539	2007
The risk of malarial infections and disease in Papua New Guinean children. The American journal of tropical medicine and hygiene\| PubMed ID: 17556601	2007
gammadelta-T cells expressing NK receptors predominate over NK cells and conventional T cells in the innate IFN-gamma response to Plasmodium falciparum malaria. European journal of immunology\| PubMed ID: 17557374	2007
Host-pathogen interactions: pas de deux. Current opinion in immunology\| PubMed ID: 17702557	2007
The role of leukocytes bearing Natural Killer Complex receptors and Killer Immunoglobulin-like Receptors in the immunology of malaria. Current opinion in immunology\| PubMed ID: 17702559	2007
Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells. The Journal of experimental medicine\| PubMed ID: 17923506	2007
Plasmodium falciparum erythrocyte membrane protein-1 specifically suppresses early production of host interferon-gamma. Cell host & microbe\| PubMed ID: 18005727	2007
Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18799734	2008
Association of early interferon-gamma production with immunity to clinical malaria: a longitudinal study among Papua New Guinean children. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 18947328	2008
IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection. PLoS pathogens\| PubMed ID: 19343215	2009
Mechanisms underlying early interferon-gamma production in human Plasmodium falciparum malaria. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 19374562	2009
Cellular tumor necrosis factor, gamma interferon, and interleukin-6 responses as correlates of immunity and risk of clinical Plasmodium falciparum malaria in children from Papua New Guinea. Infection and immunity\| PubMed ID: 19380468	2009
Analysis of FOXP3+ regulatory T cells that display apparent viral antigen specificity during chronic hepatitis C virus infection. PLoS pathogens\| PubMed ID: 20041222	2009
Estimating the proportion of microarray probes expressed in an RNA sample. Nucleic acids research\| PubMed ID: 20056656	2010
Differential patterns of infection and disease with P. falciparum and P. vivax in young Papua New Guinean children. PloS one\| PubMed ID: 20140220	2010
Murine cerebral malaria: the whole story. Trends in parasitology\| PubMed ID: 20382078	2010
Natural regulatory T cells in malaria: host or parasite allies? PLoS pathogens\| PubMed ID: 20442856	2010
The role of age and exposure to Plasmodium falciparum in the rate of acquisition of naturally acquired immunity: a randomized controlled trial. PloS one\| PubMed ID: 22412865	2012
Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to Plasmodium falciparum and P. vivax: a randomized controlled trial. PLoS medicine\| PubMed ID: 22479155	2012
Effective adjunctive therapy by an innate defense regulatory peptide in a preclinical model of severe malaria. Science translational medicine\| PubMed ID: 22623740	2012
NK cells and conventional dendritic cells engage in reciprocal activation for the induction of inflammatory responses during Plasmodium berghei ANKA infection. Immunobiology\| PubMed ID: 22704523	2012
Efficient Measurement of Opsonising Antibodies to Plasmodium falciparum Merozoites. PloS one\| PubMed ID: 23300556	2012
Opsonising antibodies to P. falciparum merozoites associated with immunity to clinical malaria. PloS one\| PubMed ID: 24040299	2013
Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow. Blood\| PubMed ID: 24335496	2014
Severity of anaemia is associated with bone marrow haemozoin in children exposed to Plasmodium falciparum. British journal of haematology\| PubMed ID: 24386973	2014
γδ T cells and CD14+ Monocytes Are Predominant Cellular Sources of Cytokines and Chemokines Associated With Severe Malaria. The Journal of infectious diseases\| PubMed ID: 24523513	2014
The contribution of natural killer complex loci to the development of experimental cerebral malaria. PloS one\| PubMed ID: 24691125	2014
Evaluation of a novel magneto-optical method for the detection of malaria parasites. PloS one\| PubMed ID: 24824542	2014