Michael Chorny

Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania

Affiliated withThe Children's Hospital of Philadelphia, University of Pennsylvania

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2014

Other Publications

Article	Year
Lipophilic drug loaded nanospheres prepared by nanoprecipitation: effect of formulation variables on size, drug recovery and release kinetics. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 12387947	2002
Study of the drug release mechanism from tyrphostin AG-1295-loaded nanospheres by in situ and external sink methods. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 12387948	2002
Inhibition of aortic allograft vasculopathy by local delivery of platelet-derived growth factor receptor tyrosine-kinase blocker AG-1295. Transplantation\| PubMed ID: 12451275	2002
Development and validation of a stability-indicating high performance liquid chromatographic assay for benoxinate. Journal of pharmaceutical and biomedical analysis\| PubMed ID: 12852462	2003
Long-term stability study of L-adrenaline injections: Kinetics of sulfonation and racemization pathways of drug degradation. Journal of pharmaceutical sciences\| PubMed ID: 14999733	2004
Locally delivered nanoencapsulated tyrphostin (AGL-2043) reduces neointima formation in balloon-injured rat carotid and stented porcine coronary arteries. Biomaterials\| PubMed ID: 15275819	2005
Tyrphostin AGL-2043 eluting stent reduces neointima formation in porcine coronary arteries. Cardiovascular research\| PubMed ID: 15364624	2004
Site-specific delivery of dexamethasone from biodegradable implants reduces formation of pericardial adhesions in rabbits. Journal of biomedical materials research. Part A\| PubMed ID: 16628712	2006
Adenoviral gene vector tethering to nanoparticle surfaces results in receptor-independent cell entry and increased transgene expression. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 16807119	2006
Magnetically driven plasmid DNA delivery with biodegradable polymeric nanoparticles. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17403937	2007
High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18182491	2008
Single and double emulsion manufacturing techniques of an amphiphilic drug in PLGA nanoparticles: formulations of mithramycin and bioactivity. Journal of pharmaceutical sciences\| PubMed ID: 18704956	2009
A new double emulsion solvent diffusion technique for encapsulating hydrophilic molecules in PLGA nanoparticles. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 18848962	2009
Predicting in vivo efficacy of potential restenosis therapies by cell culture studies: species-dependent susceptibility of vascular smooth muscle cells. The open cardiovascular medicine journal\| PubMed ID: 18949101	2008
Site-specific analgesia with sustained release liposomes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19416926	2009
Magnetically responsive biodegradable nanoparticles enhance adenoviral gene transfer in cultured smooth muscle and endothelial cells. Molecular pharmaceutics\| PubMed ID: 19496618	2009
Site-specific gene therapy for cardiovascular disease. Current opinion in drug discovery & development\| PubMed ID: 20205054	2010
Targeting stents with local delivery of paclitaxel-loaded magnetic nanoparticles using uniform fields. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20404175	2010
Endothelial delivery of antioxidant enzymes loaded into non-polymeric magnetic nanoparticles. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 20483366	2010
Magnetic nanoparticles for targeted vascular delivery. IUBMB life\| PubMed ID: 21721100	2011
Formulation and in vitro characterization of composite biodegradable magnetic nanoparticles for magnetically guided cell delivery. Pharmaceutical research\| PubMed ID: 22274555	2012
Magnetically targeted delivery of therapeutic agents to injured blood vessels for prevention of in-stent restenosis. Methodist DeBakey cardiovascular journal\| PubMed ID: 22891107	2012
Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 23241403	2013
Site-specific gene delivery to stented arteries using magnetically guided zinc oleate-based nanoparticles loaded with adenoviral vectors. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23407712	2013
Adenoviral vector tethering to metal surfaces via hydrolyzable cross-linkers for the modulation of vector release and transduction. Biomaterials\| PubMed ID: 23777912	2013
Modulation of NO and ROS production by AdiNOS transduced vascular cells through supplementation with L-Arg and BH4: implications for gene therapy of restenosis. Atherosclerosis\| PubMed ID: 23958248	2013
Endothelial targeting of nanocarriers loaded with antioxidant enzymes for protection against vascular oxidative stress and inflammation. Biomaterials\| PubMed ID: 24480537	2014
Real-time analysis of composite magnetic nanoparticle disassembly in vascular cells and biomimetic media. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24591603	2014
Targeting to endothelial cells augments the protective effect of novel dual bioactive antioxidant/anti-inflammatory nanoparticles. Molecular pharmaceutics\| PubMed ID: 24877560	2014