Dawn E. Bowles

Department of Surgery, Duke University Medical Center

Affiliated withDuke University Medical Center Duke University

Research Area

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JoVE Journal Publications

ArticleTotal : 4	Year
Publication title Cited by 22	2014
Publication title Cited by 4	2018
Publication title Cited by 11	2022
Publication title Cited by 2	2025

Other Publications

Article	Year
Marker rescue of adeno-associated virus (AAV) capsid mutants: a novel approach for chimeric AAV production. Journal of virology\| PubMed ID: 12477847	2003
Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups. Journal of virology\| PubMed ID: 15078923	2004
Adeno-associated virus vectors: potential applications for cancer gene therapy. Cancer gene therapy\| PubMed ID: 15962012	2005
Utility of telomerase-pot1 fusion protein in vascular tissue engineering. Cell transplantation\| PubMed ID: 19878625	2010
Adaptation in a mouse colony monoassociated with Escherichia coli K-12 for more than 1,000 days. Applied and environmental microbiology\| PubMed ID: 20472724	2010
Short-lived alpha-helical intermediates in the folding of beta-sheet proteins. Biochemistry\| PubMed ID: 20515035	2010
Osteopontin and protein kinase C regulate PDLIM2 activation and STAT1 ubiquitination in LPS-treated murine macrophages. The Journal of biological chemistry\| PubMed ID: 20889505	2010
Reproducibility of left atrial ablation with high-intensity focused ultrasound energy in a calf model. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 20934725	2010
AMPK and substrate availability regulate creatine transport in cultured cardiomyocytes. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 21364119	2011
Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21896730	2011
Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 22068425	2012
X-Linked Inhibitor of Apoptosis Protein-Mediated Attenuation of Apoptosis, Using a Novel Cardiac-Enhanced Adeno-Associated Viral Vector. Human gene therapy\| PubMed ID: 22339372	2012
Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles. Journal of virology\| PubMed ID: 22593151	2012
Adeno-associated viral vectors based on serotype 3b use components of the fibroblast growth factor receptor signaling complex for efficient transduction. Human gene therapy\| PubMed ID: 22680698	2012
Gene therapy for the prevention of vein graft disease. Translational research : the journal of laboratory and clinical medicine\| PubMed ID: 23274305	2013
Proteomic analysis of the NOS2 interactome in human airway epithelial cells. Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society\| PubMed ID: 23438482	2013
Phosphoproteomic profiling of human myocardial tissues distinguishes ischemic from non-ischemic end stage heart failure. PloS one\| PubMed ID: 25117565	2014
Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens. Addiction biology\| PubMed ID: 25123018	2016
Effects of left ventricular assist device support on biomarkers of cardiovascular stress, fibrosis, fluid homeostasis, inflammation, and renal injury. JACC. Heart failure\| PubMed ID: 25447345	2015
RNA-Mediated Reprogramming of Primary Adult Human Dermal Fibroblasts into c-kit(+) Cardiac Progenitor Cells. Stem cells and development\| PubMed ID: 26176491	2015
Elevated Cardiac Troponin I in Preservation Solution Is Associated With Primary Graft Dysfunction. Journal of cardiac failure\| PubMed ID: 26365053	2016
Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support. Journal of the American College of Cardiology\| PubMed ID: 26796394	2016
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection. Scientific reports\| PubMed ID: 27670941	2016
Plasma Levels of MicroRNA-155 Are Upregulated with Long-Term Left Ventricular Assist Device Support. ASAIO journal (American Society for Artificial Internal Organs : 1992)\| PubMed ID: 28319523	2017
Hypoxia decreases creatine uptake in cardiomyocytes, while creatine supplementation enhances HIF activation. Physiological reports\| PubMed ID: 28821596	2017
Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling. JCI insight\| PubMed ID: 28878120	2017
S-Nitrosylation of β-Arrestins Biases Receptor Signaling and Confers Ligand Independence. Molecular cell\| PubMed ID: 29727618	2018
The nuclear receptor RORα protects against angiotensin II-induced cardiac hypertrophy and heart failure. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 30387679	2019
NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase. Antioxidants & redox signaling\| PubMed ID: 30450923	2019
A mole rat's gut microbiota suggests selective influence of diet on microbial niche space and evolution. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 30760029	2019
A normothermic ex vivo organ perfusion delivery method for cardiac transplantation gene therapy. Scientific reports\| PubMed ID: 31142753	2019
The use of an inexpensive processing aid device (the Mouse PAD) to facilitate rodent tissue banking. BioTechniques\| PubMed ID: 32418443	2020
Evolution of bacteria in the human gut in response to changing environments: An invisible player in the game of health. Computational and structural biotechnology journal\| PubMed ID: 33552447	2021
Consequences of space radiation on the brain and cardiovascular system. Journal of environmental science and health. Part C, Toxicology and carcinogenesis\| PubMed ID: 33902387	2021
Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure. Cell death discovery\| PubMed ID: 34689154	2021
Targeted Delivery for Cardiac Regeneration: Comparison of Intra-coronary Infusion and Intra-myocardial Injection in Porcine Hearts. Frontiers in cardiovascular medicine\| PubMed ID: 35224061	2022
Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure. iScience\| PubMed ID: 35378858	2022
Ex Vivo Delivery of Viral Vectors by Organ Perfusion for Cardiac Transplantation Gene Therapy. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 36040600	2022
Transvenous Endomyocardial Biopsy Technique for Intra-abdominal Heterotopic Cardiac Grafts. Journal of cardiovascular translational research\| PubMed ID: 36344902	2023
An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair. Cell stem cell\| PubMed ID: 36516837	2023
Gene Delivery to Porcine Cardiac Allografts Using a Myocardial-Enhanced Adeno-Associated Viral Vector. Human gene therapy\| PubMed ID: 36927038	2023
Video analysis of beating hearts during preservation on the TransMedics® organ care system. Frontiers in cardiovascular medicine\| PubMed ID: 37408655	2023
Metabolomic profiling during ex situ normothermic perfusion before heart transplantation defines patterns of substrate utilization and correlates with markers of allograft injury. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 38065238	2024
GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis. Nature communications\| PubMed ID: 38081847	2023
Gene Therapy in Organ Transplantation: Considerations and Clinical Translation. Human gene therapy\| PubMed ID: 38131288	2024
GRAF1 Acts as a Downstream Mediator of Parkin to Regulate Mitophagy in Cardiomyocytes. Cells\| PubMed ID: 38474413	2024
Proteomic and phosphoproteomic characterization of cardiovascular tissues after long term exposure to simulated space radiation. Frontiers in physiology\| PubMed ID: 38699144	2024
Cardiac magnetic resonance imaging characterization of acute rejection in a porcine heterotopic heart transplantation model. PloS one\| PubMed ID: 38829911	2024
Deep Learning Resolves Myovascular Dynamics in the Failing Human Heart. JACC. Basic to translational science\| PubMed ID: 38984052	2024
Comprehensive Flow Cytometric, Immunohistologic, and Molecular Assessment of Thymus Function in Rhesus Macaques. ImmunoHorizons\| PubMed ID: 39018546	2024
Editorial: Graft preservation. Frontiers in cardiovascular medicine\| PubMed ID: 39526188	2024
Current approaches to optimize the donor heart for transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 39730081	2025