Jeremy Nathans

Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine

Affiliated withHoward Hughes Medical Institute, Johns Hopkins University School of Medicine

Research Area

Neuroscience

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 25	2014

Other Publications

Article	Year
Role of a locus control region in the mutually exclusive expression of human red and green cone pigment genes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11773636	2002
The vitelliform macular dystrophy protein defines a new family of chloride channels. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11904445	2002
Frizzled-3 is required for the development of major fiber tracts in the rostral CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12351730	2002
A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12657690	2003
Structure-function analysis of the bestrophin family of anion channels. The Journal of biological chemistry\| PubMed ID: 12907679	2003
Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14500905	2003
A strabismus susceptibility locus on chromosome 7p. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14519848	2003
Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science (New York, N.Y.)\| PubMed ID: 14671310	2003
Proximal and distal sequences control UV cone pigment gene expression in transgenic zebrafish. The Journal of biological chemistry\| PubMed ID: 14966125	2004
An outer segment localization signal at the C terminus of the photoreceptor-specific retinol dehydrogenase. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15028754	2004
Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell\| PubMed ID: 15035989	2004
Frizzled6 controls hair patterning in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15169958	2004
Proteolytic shedding of the extracellular domain of photoreceptor cadherin. Implications for outer segment assembly. The Journal of biological chemistry\| PubMed ID: 15284225	2004
Quantitative analysis of neuronal morphologies in the mouse retina visualized by using a genetically directed reporter. The Journal of comparative neurology\| PubMed ID: 15558785	2004
The rod photoreceptor-specific nuclear receptor Nr2e3 represses transcription of multiple cone-specific genes. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15634773	2005
The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15872101	2005
Written in our genes? Science (New York, N.Y.)\| PubMed ID: 15961653	2005
Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16407530	2006
An evolutionary perspective on the photoreceptor damage response. American journal of ophthalmology\| PubMed ID: 16490507	2006
The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16495441	2006
Ca2+-activated Cl- current from human bestrophin-4 in excised membrane patches. The Journal of general physiology\| PubMed ID: 16702355	2006
Effects of L1 retrotransposon insertion on transcript processing, localization and accumulation: lessons from the retinal degeneration 7 mouse and implications for the genomic ecology of L1 ... Human molecular genetics\| PubMed ID: 16723373	2006
Macular degeneration: recent advances and therapeutic opportunities. Nature reviews. Neuroscience\| PubMed ID: 17033682	2006
Mutational analysis of Norrin-Frizzled4 recognition. The Journal of biological chemistry\| PubMed ID: 17158104	2007
Order from disorder: Self-organization in mammalian hair patterning. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17172440	2006
Tissue/planar cell polarity in vertebrates: new insights and new questions. Development (Cambridge, England)\| PubMed ID: 17259302	2007
Emergence of novel color vision in mice engineered to express a human cone photopigment. Science (New York, N.Y.)\| PubMed ID: 17379811	2007
Genetic ablation of cone photoreceptors eliminates retinal folds in the retinal degeneration 7 (rd7) mouse. Investigative ophthalmology & visual science\| PubMed ID: 17525215	2007
Estrogen-related receptor beta/NR3B2 controls epithelial cell fate and endolymph production by the stria vascularis. Developmental cell\| PubMed ID: 17765677	2007
The optokinetic reflex as a tool for quantitative analyses of nervous system function in mice: application to genetic and drug-induced variation. PloS one\| PubMed ID: 18446207	2008
An essential role for Frizzled5 in neuronal survival in the parafascicular nucleus of the thalamus. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18509025	2008
The genomic response of the retinal pigment epithelium to light damage and retinal detachment. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18815272	2008
An essential role for frizzled 5 in mammalian ocular development. Development (Cambridge, England)\| PubMed ID: 18832390	2008
Genetically-directed, cell type-specific sparse labeling for the analysis of neuronal morphology. PloS one\| PubMed ID: 19116659	2008
Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells. Neuron\| PubMed ID: 19323995	2009
The evolution of Primate color vision. Scientific American\| PubMed ID: 19363921	2009
Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell\| PubMed ID: 19837032	2009
New mouse lines for the analysis of neuronal morphology using CreER(T)/loxP-directed sparse labeling. PloS one\| PubMed ID: 19924248	2009
An MRI-based atlas and database of the developing mouse brain. NeuroImage\| PubMed ID: 20656042	2011
The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease. Trends in molecular medicine\| PubMed ID: 20688566	2010
Morphologies of mouse retinal ganglion cells expressing transcription factors Brn3a, Brn3b, and Brn3c: analysis of wild type and mutant cells using genetically-directed sparse labeling. Vision research\| PubMed ID: 20826176	2011
Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes. Development (Cambridge, England)\| PubMed ID: 20940229	2010
Expression of the Norrie disease gene (Ndp) in developing and adult mouse eye, ear, and brain. Gene expression patterns : GEP\| PubMed ID: 21055480	2011
When whorls collide: the development of hair patterns in frizzled 6 mutant mice. Development (Cambridge, England)\| PubMed ID: 21062866	2010
China's plan flawed but courageous. Science (New York, N.Y.)\| PubMed ID: 21163997	2010
Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney. Development (Cambridge, England)\| PubMed ID: 21343368	2011
Preclinical assessment of CNS drug action using eye movements in mice. The Journal of clinical investigation\| PubMed ID: 21821912	2011
Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron\| PubMed ID: 21835343	2011
Signaling by sensory receptors. Cold Spring Harbor perspectives in biology\| PubMed ID: 22110046	2012
Combinatorial expression of Brn3 transcription factors in somatosensory neurons: genetic and morphologic analysis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22262898	2012
Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes. Development (Cambridge, England)\| PubMed ID: 23095888	2012
Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity. Cell\| PubMed ID: 23217714	2012
Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling. eLife\| PubMed ID: 23256042	2012
Responses of hair follicle-associated structures to loss of planar cell polarity signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23431170	2013
How to draw the line in biomedical research. eLife\| PubMed ID: 23538852	2013
Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24043815	2013
Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons. eLife\| PubMed ID: 24347548	2013
Cellular resolution maps of X chromosome inactivation: implications for neural development, function, and disease. Neuron\| PubMed ID: 24411735	2014
Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24799694	2014
Complete morphologies of basal forebrain cholinergic neurons in the mouse. eLife\| PubMed ID: 24894464	2014