Simon Alford

Biological Sciences, University of Illinois at Chicago

Affiliated withUniversity of Illinois at Chicago University of Illinois at Chicago College of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 1	2014
Publication title	2019
Publication title Cited by 3	2019

Other Publications

Article	Year
Gbetagamma acts at the C terminus of SNAP-25 to mediate presynaptic inhibition. Nature neuroscience\| PubMed ID: 15834421	2005
Computational analysis in vitro: dynamics and plasticity of a neuro-robotic system. Journal of neural engineering\| PubMed ID: 16135888	2005
Calcium influx-independent depression of transmitter release by 5-HT at lamprey spinal cord synapses. The Journal of physiology\| PubMed ID: 11306653	2001
The requirement of presynaptic metabotropic glutamate receptors for the maintenance of locomotion. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11978845	2002
Presynaptic GABAA and GABAB Receptor-mediated Phasic Modulation in Axons of Spinal Motor Interneurons. The European journal of neuroscience\| PubMed ID: 12106209	1991
Dynamical dimension of a hybrid neurorobotic system. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society\| PubMed ID: 12899261	2003
The pharmacology of vertebrate spinal central pattern generators. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry\| PubMed ID: 15065817	2003
Quantitative investigation of calcium signals for locomotor pattern generation in the lamprey spinal cord. Journal of neurophysiology\| PubMed ID: 15140901	2004
5-HT prolongs ventral root bursting via presynaptic inhibition of synaptic activity during fictive locomotion in lamprey. Journal of neurophysiology\| PubMed ID: 15456802	2005
G protein betagamma directly regulates SNARE protein fusion machinery for secretory granule exocytosis. Nature neuroscience\| PubMed ID: 15778713	2005
Location and function of vesicle clusters, active zones and Ca2+ channels in the lamprey presynaptic terminal. The Journal of physiology\| PubMed ID: 16141275	2005
G protein betagamma-subunits activated by serotonin mediate presynaptic inhibition by regulating vesicle fusion properties. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16537522	2006
Presynaptic G-protein-coupled receptors regulate synaptic cleft glutamate via transient vesicle fusion. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17537956	2007
Gbetagamma interferes with Ca2+-dependent binding of synaptotagmin to the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex. Molecular pharmacology\| PubMed ID: 17715396	2007
Brain-machine interactions for assessing the dynamics of neural systems. Frontiers in neurorobotics\| PubMed ID: 19430593	2009
Presynaptic G-protein-coupled receptors dynamically modify vesicle fusion, synaptic cleft glutamate concentrations, and motor behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19692597	2009
A parallel cholinergic brainstem pathway for enhancing locomotor drive. Nature neuroscience\| PubMed ID: 20473293	2010
New Perspectives on the Dialogue between Brains and Machines. Frontiers in neuroscience\| PubMed ID: 20589094	2010
Phosphorylation-state-dependent regulation of NMDA receptor short-term plasticity modifies hippocampal dendritic Ca2+ transients. Journal of neurophysiology\| PubMed ID: 20719921	2010
Spotlight on the active zone. Cellular logistics\| PubMed ID: 21922071	2011
Extracellular pH dynamics of retinal horizontal cells examined using electrochemical and fluorometric methods. Journal of neurophysiology\| PubMed ID: 22090459	2012
Dual pools of actin at presynaptic terminals. Journal of neurophysiology\| PubMed ID: 22457456	2012
Role of presynaptic metabotropic glutamate receptors in the induction of long-term synaptic plasticity of vesicular release. Neuropharmacology\| PubMed ID: 22626985	2013
Gβγ inhibits exocytosis via interaction with critical residues on soluble N-ethylmaleimide-sensitive factor attachment protein-25. Molecular pharmacology\| PubMed ID: 22962332	2012
Differential regulation of synaptic transmission by pre- and postsynaptic SK channels in the spinal locomotor network. Journal of neurophysiology\| PubMed ID: 23554432	2013
Synaptic NMDA receptor-dependent Ca²⁺ entry drives membrane potential and Ca²⁺ oscillations in spinal ventral horn neurons. PloS one\| PubMed ID: 23646190	2013
Forebrain dopamine neurons project down to a brainstem region controlling locomotion. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23918379	2013
Fluorescent imaging reports an extracellular alkalinization induced by glutamatergic activation of isolated retinal horizontal cells. Journal of neurophysiology\| PubMed ID: 24335210	2014
Modulation of neurotransmission by GPCRs is dependent upon the microarchitecture of the primed vesicle complex. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24381287	2014
The NHS health check programme in England: a qualitative study. Health promotion international\| PubMed ID: 25073761	2014
A synaptic mechanism for network synchrony. Frontiers in cellular neuroscience\| PubMed ID: 25278839	2014
Sensory Activation of Command Cells for Locomotion and Modulatory Mechanisms: Lessons from Lampreys. Frontiers in neural circuits\| PubMed ID: 27047342	2016
A descending dopamine pathway conserved from basal vertebrates to mammals. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27071118	2016
Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes. The Journal of biological chemistry\| PubMed ID: 28515322	2017
Gβγ SNARE Interactions and Their Behavioral Effects. Neurochemical research\| PubMed ID: 29752624	2019
Disabling the Gβγ-SNARE interaction disrupts GPCR-mediated presynaptic inhibition, leading to physiological and behavioral phenotypes. Science signaling\| PubMed ID: 30783011	2019
Extracellular and intracellular sphingosine-1-phosphate distinctly regulates exocytosis in chromaffin cells. Journal of neurochemistry\| PubMed ID: 30963576	2019
Physiological roles for neuromodulation via G GPCRs working through Gβγ-SNARE interaction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 31477818	2019
Quantitation and simulation of single action potential-evoked Ca signals in CA1 pyramidal neuron presynaptic terminals. eNeuro\| PubMed ID: 31551250	2019