J. Marie Hardwick

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health

Affiliated withJohns Hopkins University Bloomberg School of Public Health

Research Area

Biology

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 32	2015
Publication title Cited by 5	2016

Other Publications

Article	Year
Epstein-Barr virus BALF1 is a BCL-2-like antagonist of the herpesvirus antiapoptotic BCL-2 proteins. Journal of virology\| PubMed ID: 11836425	2002
Inhibitor specificity of recombinant and endogenous caspase-9. The Biochemical journal\| PubMed ID: 12067274	2002
BCL-2 and BAX protect adult mice from lethal Sindbis virus infection but do not protect spinal cord motor neurons or prevent paralysis. Journal of virology\| PubMed ID: 12239316	2002
Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature. The Journal of biological chemistry\| PubMed ID: 12381734	2002
Bax, along with lipid conspirators, allows cytochrome c to escape mitochondria. Molecular cell\| PubMed ID: 12453403	2002
BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development. Developmental cell\| PubMed ID: 12689595	2003
Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins. The Journal of clinical investigation\| PubMed ID: 12840065	2003
Enhancing DNA vaccine potency by combining a strategy to prolong dendritic cell life with intracellular targeting strategies. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12960321	2003
Modulation of synaptic transmission by the BCL-2 family protein BCL-xL. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12968005	2003
Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper. Molecular biology of the cell\| PubMed ID: 14517326	2003
A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures. Metabolic engineering\| PubMed ID: 14642351	2003
Viral modulators of cell death provide new links to old pathways. Current opinion in cell biology\| PubMed ID: 14644194	2003
Regulation of cell death in the lymphoid system by Bcl-2 family proteins. Acta haematologica\| PubMed ID: 14646344	2004
Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold. Proteins\| PubMed ID: 14705031	2004
Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions. Biotechnology and bioengineering\| PubMed ID: 14966800	2004
Viral Bcl-2 homologs and their role in virus replication and associated diseases. Biochimica et biophysica acta\| PubMed ID: 14996505	2004
Neuronal apoptosis pathways in Sindbis virus encephalitis. Progress in molecular and subcellular biology\| PubMed ID: 15171608	2004
BAD is a pro-survival factor prior to activation of its pro-apoptotic function. The Journal of biological chemistry\| PubMed ID: 15231831	2004
Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15342906	2004
Mitochondrial fission proteins regulate programmed cell death in yeast. Genes & development\| PubMed ID: 15520274	2004
Mitochondrial programmed cell death pathways in yeast. Developmental cell\| PubMed ID: 15525523	2004
Exposure to hypoxia rapidly induces mitochondrial channel activity within a living synapse. The Journal of biological chemistry\| PubMed ID: 15561723	2005
Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. The Journal of biological chemistry\| PubMed ID: 15590628	2005
Modification of professional antigen-presenting cells with small interfering RNA in vivo to enhance cancer vaccine potency. Cancer research\| PubMed ID: 15665308	2005
Magnetic resonance diffusion tensor microimaging reveals a role for Bcl-x in brain development and homeostasis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15728827	2005
Viruses activate a genetically conserved cell death pathway in a unicellular organism. The Journal of cell biology\| PubMed ID: 16061692	2005
Actions of BAX on mitochondrial channel activity and on synaptic transmission. Antioxidants & redox signaling\| PubMed ID: 16115013	2005
Combining caspase and mitochondrial dysfunction inhibitors of apoptosis to limit cell death in mammalian cell cultures. Biotechnology and bioengineering\| PubMed ID: 16598795	2006
Zinc-dependent multi-conductance channel activity in mitochondria isolated from ischemic brain. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16793892	2006
Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells. Biotechnology and bioengineering\| PubMed ID: 17099908	2007
Upgrading the BCL-2 network. Nature cell biology\| PubMed ID: 17139279	2006
A Bcl-xL timer sets platelet life span. Cell\| PubMed ID: 17382877	2007
A quorum on bacterial programmed cell death. Molecular cell\| PubMed ID: 18042446	2007
Bcl-xL inhibitor ABT-737 reveals a dual role for Bcl-xL in synaptic transmission. Journal of neurophysiology\| PubMed ID: 18160428	2008
Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels. The Journal of biological chemistry\| PubMed ID: 18171672	2008
Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18250306	2008
Mitochondrial death pathways in yeast and mammalian cells. Biochimica et biophysica acta\| PubMed ID: 18477482	2008
Unravelling the bcl-2 apoptosis code with a simple model system. PLoS biology\| PubMed ID: 18563968	2008
Aven-dependent activation of ATM following DNA damage. Current biology : CB\| PubMed ID: 18571408	2008
Bcl-2 turns deadly. Nature chemical biology\| PubMed ID: 19008882	2008
Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons. The Journal of cell biology\| PubMed ID: 19255249	2009
Reliable method for detection of programmed cell death in yeast. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19609767	2009
SnapShot: BCL-2 proteins. Cell\| PubMed ID: 19632186	2009
The apoptosome at high resolution. Cell\| PubMed ID: 20434981	2010
Seizure tests distinguish intermittent fasting from the ketogenic diet. Epilepsia\| PubMed ID: 20477852	2010
Mitochondrial involvement in cell death of non-mammalian eukaryotes. Biochimica et biophysica acta\| PubMed ID: 20950655	2011
Flying to a halt: Drosophila Aven arrests the cell cycle. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21487234	2011
Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase. Nature cell biology\| PubMed ID: 21926988	2011
Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential. The Journal of cell biology\| PubMed ID: 21987637	2011
N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death. Nature neuroscience\| PubMed ID: 22366758	2012
Multipolar functions of BCL-2 proteins link energetics to apoptosis. Trends in cell biology\| PubMed ID: 22560661	2012
The mTOR inhibitor rapamycin has limited acute anticonvulsant effects in mice. PloS one\| PubMed ID: 22984623	2012
A new view of the lethal apoptotic pore. PLoS biology\| PubMed ID: 23049484	2012
Evolution of Bcl-2 homology motifs: homology versus homoplasy. Trends in cell biology\| PubMed ID: 23199982	2013
The N-terminal helix of Bcl-xL targets mitochondria. Mitochondrion\| PubMed ID: 23333404	2013
Unlatched BAX pairs for death. Cell\| PubMed ID: 23374333	2013
Multiple functions of BCL-2 family proteins. Cold Spring Harbor perspectives in biology\| PubMed ID: 23378584	2013
Quantification of genetically controlled cell death in budding yeast. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23733576	2013
Genome-wide consequences of deleting any single gene. Molecular cell\| PubMed ID: 24211263	2013
Cell death in genome evolution. Seminars in cell & developmental biology\| PubMed ID: 25725369	2015
In vivo CaspaseTracker biosensor system for detecting anastasis and non-apoptotic caspase activity. Scientific reports\| PubMed ID: 25757939	2015
Potent anti-seizure effects of D-leucine. Neurobiology of disease\| PubMed ID: 26054437	2015
Redefining the BH3 Death Domain as a 'Short Linear Motif'. Trends in biochemical sciences\| PubMed ID: 26541461	2015