Akiko Mammoto

Vascular Biology Program, Boston Children's Hospital and Harvard Medical School

Affiliated withBoston Children's Hospital and Harvard Medical School

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2014

Other Publications

Article	Year
Infiltration anesthetic lidocaine inhibits cancer cell invasion by modulating ectodomain shedding of heparin-binding epidermal growth factor-like growth factor (HB-EGF). Journal of cellular physiology\| PubMed ID: 12124780	2002
Intravenous anesthetic, propofol inhibits invasion of cancer cells. Cancer letters\| PubMed ID: 12127688	2002
Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. The Journal of cell biology\| PubMed ID: 14597771	2003
Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition. The Journal of biological chemistry\| PubMed ID: 15096506	2004
Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts. Journal of cell science\| PubMed ID: 17227794	2007
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood\| PubMed ID: 17392504	2007
Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo. The Journal of biological chemistry\| PubMed ID: 17562701	2007
Rho signaling and mechanical control of vascular development. Current opinion in hematology\| PubMed ID: 18391790	2008
ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells. The Journal of biological chemistry\| PubMed ID: 18660502	2008
Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18685096	2008
Methods for studying mechanical control of angiogenesis by the cytoskeleton and extracellular matrix. Methods in enzymology\| PubMed ID: 18772019	2008
A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature\| PubMed ID: 19242469	2009
TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circulation research\| PubMed ID: 19359599	2009
Discovery of potent and practical antiangiogenic agents inspired by cortistatin A. Journal of the American Chemical Society\| PubMed ID: 19469509	2009
Cytoskeletal control of growth and cell fate switching. Current opinion in cell biology\| PubMed ID: 19740640	2009
Paper-supported 3D cell culture for tissue-based bioassays. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19846768	2009
Reconstituting organ-level lung functions on a chip. Science (New York, N.Y.)\| PubMed ID: 20576885	2010
Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 20725677	2010
Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion. The Journal of experimental medicine\| PubMed ID: 20937704	2010
Multizone paper platform for 3D cell cultures. PloS one\| PubMed ID: 21573103	2011
Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation. Developmental cell\| PubMed ID: 21924961	2011
Wnt signaling mediates pathological vascular growth in proliferative retinopathy. Circulation\| PubMed ID: 21969016	2011
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. The Journal of clinical investigation\| PubMed ID: 22182838	2012
Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning. PloS one\| PubMed ID: 22194823	2011
A combined micromagnetic-microfluidic device for rapid capture and culture of rare circulating tumor cells. Lab on a chip\| PubMed ID: 22453808	2012
Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix. Nano letters\| PubMed ID: 22554317	2012
Mechanosensitive mechanisms in transcriptional regulation. Journal of cell science\| PubMed ID: 22797927	2012
LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway. PloS one\| PubMed ID: 22848540	2012
Paxillin controls directional cell motility in response to physical cues. Cell adhesion & migration\| PubMed ID: 23076140	2012
Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein. The Journal of biological chemistry\| PubMed ID: 23195957	2013
Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics. Nature communications\| PubMed ID: 23612300	2013
Platelet rich plasma extract promotes angiogenesis through the angiopoietin1-Tie2 pathway. Microvascular research\| PubMed ID: 23660186	2013
Low urine vascular endothelial growth factor levels are associated with mechanical ventilation, bronchopulmonary dysplasia and retinopathy of prematurity. Neonatology\| PubMed ID: 23711562	2013
Breast cancer normalization induced by embryonic mesenchyme is mediated by extracellular matrix biglycan. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 23817524	2013
Extracellular matrix structure and tissue stiffness control postnatal lung development through the lipoprotein receptor-related protein 5/Tie2 signaling system. American journal of respiratory cell and molecular biology\| PubMed ID: 23841513	2013
GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2. Angiogenesis\| PubMed ID: 23892628	2013
Epoxyeicosanoids promote organ and tissue regeneration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23898174	2013
Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression. The American journal of pathology\| PubMed ID: 23928381	2013
Twist1 controls lung vascular permeability and endotoxin-induced pulmonary edema by altering Tie2 expression. PloS one\| PubMed ID: 24023872	2013
Mechanobiology and developmental control. Annual review of cell and developmental biology\| PubMed ID: 24099083	2013
Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression. Journal of cell science\| PubMed ID: 24522185	2014
Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 24550068	2014
Mechanotransduction of fluid stresses governs 3D cell migration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24550267	2014
Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro. Nature methods\| PubMed ID: 24793454	2014
Netrin-1 promotes medulloblastoma cell invasiveness and angiogenesis, and demonstrates elevated expression in tumor tissue and urine of patients with pediatric medulloblastoma. Cancer research\| PubMed ID: 24812271	2014
RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity. The Journal of clinical investigation\| PubMed ID: 24837431	2014
Platelet-rich-plasma Extract Prevents Pulmonary Edema through Angiopoietin-Tie2 Signaling. American journal of respiratory cell and molecular biology\| PubMed ID: 24960457	2014
An extracorporeal blood-cleansing device for sepsis therapy. Nature medicine\| PubMed ID: 25216635	2014
Endothelial TWIST1 promotes pathological ocular angiogenesis. Investigative ophthalmology & visual science\| PubMed ID: 25414194	2014