Tobias Moser

InnerEarLab, University Medical Center Goettingen

Affiliated withUniversity Medical Center Goettingen University of Goettingen

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 23	2014

Other Publications

Article	Year
LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice. Human molecular genetics\| PubMed ID: 12620969	2003
Calcium regulates exocytosis at the level of single vesicles. Nature neuroscience\| PubMed ID: 12845327	2003
The afferent synapse of cochlear hair cells. Current opinion in neurobiology\| PubMed ID: 12965293	2003
CaV1.3 channels are essential for development and presynaptic activity of cochlear inner hair cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 14645476	2003
BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments. The Journal of cell biology\| PubMed ID: 15381686	2004
Hair cell synaptic ribbons are essential for synchronous auditory signalling. Nature\| PubMed ID: 15829963	2005
Few CaV1.3 channels regulate the exocytosis of a synaptic vesicle at the hair cell ribbon synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16354915	2005
Expression pattern and functional characterization of connexin29 in transgenic mice. Glia\| PubMed ID: 16435366	2006
Mice with altered KCNQ4 K+ channels implicate sensory outer hair cells in human progressive deafness. The EMBO journal\| PubMed ID: 16437162	2006
CSPalpha-deficiency causes massive and rapid photoreceptor degeneration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16477021	2006
Mechanisms underlying the temporal precision of sound coding at the inner hair cell ribbon synapse. The Journal of physiology\| PubMed ID: 16901948	2006
Hair cell ribbon synapses. Cell and tissue research\| PubMed ID: 16944206	2006
[Hearing loss -- can heat shock protein 70 be cited as prognostic marker?]. Laryngo- rhino- otologie\| PubMed ID: 17031759	2006
Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell\| PubMed ID: 17055430	2006
Intracavity generation of radially polarized CO2 laser beams based on a simple binary dielectric diffraction grating. Applied optics\| PubMed ID: 17086263	2006
Measurements of membrane patch capacitance using a software-based lock-in system. Pflügers Archiv : European journal of physiology\| PubMed ID: 17206448	2007
Maturation of ribbon synapses in hair cells is driven by thyroid hormone. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17376978	2007
Ca2+-binding proteins tune Ca2+-feedback to Cav1.3 channels in mouse auditory hair cells. The Journal of physiology\| PubMed ID: 17947313	2007
Probing the mechanism of exocytosis at the hair cell ribbon synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18032667	2007
Impairment of SLC17A8 encoding vesicular glutamate transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice. American journal of human genetics\| PubMed ID: 18674745	2008
Mechanisms contributing to synaptic Ca2+ signals and their heterogeneity in hair cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19246382	2009
Tuning of synapse number, structure and function in the cochlea. Nature neuroscience\| PubMed ID: 19270686	2009
Does a single session of theta-burst transcranial magnetic stimulation of inferior temporal cortex affect tinnitus perception? BMC neuroscience\| PubMed ID: 19480651	2009
Complexin-I is required for high-fidelity transmission at the endbulb of Held auditory synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19553439	2009
Neuroligin 2 controls the maturation of GABAergic synapses and information processing in the retina. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19553444	2009
The Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearing. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19710324	2009
Functional properties of synaptic transmission in primary sense organs. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19828792	2009
Onset coding is degraded in auditory nerve fibers from mutant mice lacking synaptic ribbons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20519533	2010
Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells. Nature neuroscience\| PubMed ID: 20562868	2010
A missense mutation in a highly conserved alternate exon of dynamin-1 causes epilepsy in fitful mice. PLoS genetics\| PubMed ID: 20700442	2010
Structure and function of cochlear afferent innervation. Current opinion in otolaryngology & head and neck surgery\| PubMed ID: 20802334	2010
The connexin26 S17F mouse mutant represents a model for the human hereditary keratitis-ichthyosis-deafness syndrome. Human molecular genetics\| PubMed ID: 20926451	2011
Bassoon and the synaptic ribbon organize Ca²+ channels and vesicles to add release sites and promote refilling. Neuron\| PubMed ID: 21092861	2010
The crystal structure of the C₂A domain of otoferlin reveals an unconventional top loop region. Journal of molecular biology\| PubMed ID: 21216247	2011
Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21282647	2011
Exocytosis at the hair cell ribbon synapse apparently operates without neuronal SNARE proteins. Nature neuroscience\| PubMed ID: 21378973	2011
Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21451027	2011
A synthetic prestin reveals protein domains and molecular operation of outer hair cell piezoelectricity. The EMBO journal\| PubMed ID: 21701557	2011
Connexin32 can restore hearing in connexin26 deficient mice. European journal of cell biology\| PubMed ID: 21813206	2011
Harmonin inhibits presynaptic Cav1.3 Ca²⁺ channels in mouse inner hair cells. Nature neuroscience\| PubMed ID: 21822269	2011
Spike encoding of neurotransmitter release timing by spiral ganglion neurons of the cochlea. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22492033	2012
The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative gene. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22787034	2012
Deletion of the presynaptic scaffold CAST reduces active zone size in rod photoreceptors and impairs visual processing. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22933801	2012
Otoferlin: a multi-C2 domain protein essential for hearing. Trends in neurosciences\| PubMed ID: 22959777	2012
A mutation in CABP2, expressed in cochlear hair cells, causes autosomal-recessive hearing impairment. American journal of human genetics\| PubMed ID: 22981119	2012
A Mutation in PNPT1, Encoding Mitochondrial-RNA-Import Protein PNPase, Causes Hereditary Hearing Loss. American journal of human genetics\| PubMed ID: 23084290	2012
A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system. Glia\| PubMed ID: 23322581	2013
Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells. Nature communications\| PubMed ID: 23385583	2013
Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23467361	2013
Harmonin enhances voltage-dependent facilitation of Cav1.3 channels and synchronous exocytosis in mouse inner hair cells. The Journal of physiology\| PubMed ID: 23613530	2013
Review of hair cell synapse defects in sensorineural hearing impairment. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology\| PubMed ID: 23628789	2013
Concurrent maturation of inner hair cell synaptic Ca2+ influx and auditory nerve spontaneous activity around hearing onset in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23804089	2013
Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24431429	2014
Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis. The EMBO journal\| PubMed ID: 24442635	2014
Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse. The EMBO journal\| PubMed ID: 24442636	2014
Optogenetic stimulation of the auditory pathway. The Journal of clinical investigation\| PubMed ID: 24509078	2014
ATP hydrolysis is critically required for function of CaV1.3 channels in cochlear inner hair cells via fueling Ca2+ clearance. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24828638	2014
A new probe for super-resolution imaging of membranes elucidates trafficking pathways. The Journal of cell biology\| PubMed ID: 24862576	2014
Uniquantal Release through a Dynamic Fusion Pore Is a Candidate Mechanism of Hair Cell Exocytosis. Neuron\| PubMed ID: 25199706	2014