Optogenetic Stimulation of the Auditory Nerve

Victor H. Hernandez; Anna Gehrt; Zhizi Jing; Gerhard Hoch; Marcus Jeschke; Nicola Strenzke; Tobias Moser

doi:10.3791/52069

Journal

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Neuroscience

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Optogenetic Stimulation of the Auditory Nerve

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

Optogenetic Stimulation of the Auditory Nerve

14,585 Views

•

10:53 min

•

October 08, 2014

DOI:

10.3791/52069-v

DOI:

10.3791/52069-v

•

10:53 min

October 08, 2014

•

14573 Views

Victor H. Hernandez^1,2,5, Anna Gehrt^1,3, Zhizi Jing³, Gerhard Hoch¹, Marcus Jeschke¹, Nicola Strenzke³, Tobias Moser^1,2,4

¹InnerEarLab, Department of Otolaryngology,University Medical Center Goettingen ²Bernstein Focus for Neurotechnology,University of Goettingen ³Auditory Systems Physiology Group, Department of Otolaryngology,University Medical Center Goettingen ⁴Center for Nanoscale Microscopy and Molecular Physiology of the Brain,University of Goettingen ⁵Department of Chemical, Electronic, and Biomedical Engineering,University of Guanajuato

Summary

Cochlear implants (CIs) enable hearing by direct electrical stimulation of the auditory nerve. However, poor frequency and intensity resolution limits the quality of hearing with CIs. Here we describe optogenetic stimulation of the auditory nerve in mice as an alternative strategy for auditory research and developing future CIs.