Alfred Fahr

Department of Pharmaceutical Technology, Friedrich-Schiller-University Jena

Affiliated withFriedrich-Schiller-University Jena

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2015

Other Publications

Article	Year
Interactions of cyclosporines with lipid membranes as studied by solid-state nuclear magnetic resonance spectroscopy and high-sensitivity titration calorimetry. Journal of pharmaceutical sciences\| PubMed ID: 11920770	2002
Sustained-release injectables formed in situ and their potential use for veterinary products. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 12480306	2002
Encapsulation of gadobutrol in AVE-based liposomal carriers for MR detectability. Magnetic resonance imaging\| PubMed ID: 15120167	2004
Efficient gene delivery with serum into human cancer cells using targeted anionic liposomes. Journal of drug targeting\| PubMed ID: 15203907	2004
Novel lipid nanotubes in dispersions of DMPC. Chemphyschem : a European journal of chemical physics and physical chemistry\| PubMed ID: 15446752	2004
Transfer of lipophilic drugs between liposomal membranes and biological interfaces: consequences for drug delivery. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 16112849	2005
Generation of immunoliposomes using recombinant single-chain Fv fragments bound to Ni-NTA-liposomes. Journal of drug targeting\| PubMed ID: 16308208	2005
Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons. RNA (New York, N.Y.)\| PubMed ID: 16699166	2006
Electrostatic model for mixed cationic-zwitterionic lipid bilayers. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 16700604	2006
Adaptive neuro-fuzzy modeling of poorly soluble drug formulations. Pharmaceutical research\| PubMed ID: 16715373	2006
Lipophilic drug transfer between liposomal and biological membranes: what does it mean for parenteral and oral drug delivery? Journal of liposome research\| PubMed ID: 16952882	2006
In vitro characterization of binding and stability of single-chain Fv Ni-NTA-liposomes. Journal of drug targeting\| PubMed ID: 17050123	2006
Physicochemical characterization of solid dispersions of three antiepileptic drugs prepared by solvent evaporation method. The Journal of pharmacy and pharmacology\| PubMed ID: 17524229	2007
Drug delivery strategies for poorly water-soluble drugs. Expert opinion on drug delivery\| PubMed ID: 17683253	2007
Using a modified shepards method for optimization of a nanoparticulate cyclosporine a formulation prepared by a static mixer technique. Journal of pharmaceutical sciences\| PubMed ID: 17853428	2008
Interaction of lipid nanoparticles with human epidermis and an organotypic cell culture model. International journal of pharmaceutics\| PubMed ID: 17920216	2008
A novel gene delivery system for stable transfection of thiopurine-S-methyltransferase gene in versatile cell types. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 17988843	2008
Temoporfin-loaded invasomes: development, characterization and in vitro skin penetration studies. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 18281119	2008
Permeability changes in response to NONOate and NONOate prodrug derived nitric oxide in a blood-brain barrier model formed by primary porcine endothelial cells. Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society\| PubMed ID: 18284923	2008
Topical application of temoporfin-loaded invasomes for photodynamic therapy of subcutaneously implanted tumours in mice: a pilot study. Journal of photochemistry and photobiology. B, Biology\| PubMed ID: 18316200	2008
Efficiency of cytoplasmic delivery by non-cationic liposomes to cells in vitro: a confocal laser scanning microscopy study. Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)\| PubMed ID: 18590977	2009
Fluorescent liposomes as contrast agents for in vivo optical imaging of edemas in mice. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 18666163	2008
Lipophilicity measurement of drugs by reversed phase HPLC over Wide pH range using an alkaline-resistant silica-based stationary phase, XBridge Shield RP(18). Chemical & pharmaceutical bulletin\| PubMed ID: 18827381	2008
Development of different temoporfin-loaded invasomes-novel nanocarriers of temoporfin: characterization, stability and in vitro skin penetration studies. Colloids and surfaces. B, Biointerfaces\| PubMed ID: 19188048	2009
Temoporfin-loaded liposomal gels: viscoelastic properties and in vitro skin penetration. International journal of pharmaceutics\| PubMed ID: 19429291	2009
Preservation of liquid drug preparations for oral administration. Journal of pharmaceutical sciences\| PubMed ID: 19499567	2010
Stability evaluation of temoporfin-loaded liposomal gels for topical application. Journal of liposome research\| PubMed ID: 19558347	2010
Development of liposomes containing ethanol for skin delivery of temoporfin: characterization and in vitro penetration studies. Colloids and surfaces. B, Biointerfaces\| PubMed ID: 19651496	2009
Supercooled smectic nanoparticles: influence of the matrix composition and in vitro cytotoxicity. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 19664705	2009
Surface charged temoporfin-loaded flexible vesicles: in vitro skin penetration studies and stability. International journal of pharmaceutics\| PubMed ID: 19819321	2010
Micro-structured smart hydrogels with enhanced protein loading and release efficiency. Acta biomaterialia\| PubMed ID: 19913647	2010
Utilization of liposomes for studying drug transfer and uptake. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20013385	2010
Flow cytometry as a new approach to investigate drug transfer between lipid particles. Molecular pharmaceutics\| PubMed ID: 20063898	2010
Temoporfin-loaded liposomes: physicochemical characterization. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 20412853	2010
Polymersomes containing iron sulfide (FeS) as primordial cell model : for the investigation of energy providing redox reactions. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life\| PubMed ID: 20697814	2011
Kinetics of aspartic acid isomerization and enantiomerization in model aspartyl tripeptides under forced conditions. Journal of pharmaceutical sciences\| PubMed ID: 20737625	2010
Efficacy of temoporfin-loaded invasomes in the photodynamic therapy in human epidermoid and colorectal tumour cell lines. Journal of photochemistry and photobiology. B, Biology\| PubMed ID: 20797872	2010
Spontaneous protein crowding in liposomes: a new vista for the origin of cellular metabolism. Chembiochem : a European journal of chemical biology\| PubMed ID: 20806308	2010
DHPC strongly affects the structure and oligomerization propensity of Alzheimer's Aβ(1-40) peptide. Journal of molecular biology\| PubMed ID: 20851128	2010
Transfer mechanism of temoporfin between liposomal membranes. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 20888878	2011
Cellular uptake and degradation behaviour of biodegradable poly(ethylene glycol-graft-methyl methacrylate) nanoparticles crosslinked with dimethacryloyl hydroxylamine. International journal of pharmaceutics\| PubMed ID: 20969936	2011
Lipophilicity and its relationship with passive drug permeation. Pharmaceutical research\| PubMed ID: 21052797	2011
Skin penetration and deposition of carboxyfluorescein and temoporfin from different lipid vesicular systems: In vitro study with finite and infinite dosage application. International journal of pharmaceutics\| PubMed ID: 21316430	2011
Skin delivery of ferulic acid from different vesicular systems. Journal of biomedical nanotechnology\| PubMed ID: 21329050	2010
Linear free energy relationship analysis of retention factors in cerasome electrokinetic chromatography intended for predicting drug skin permeation. Journal of pharmaceutical sciences\| PubMed ID: 21455982	2011
The physical state of lipid nanoparticles influences their effect on in vitro cell viability. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 21458564	2011
Lecithin-based novel cationic nanocarriers (Leciplex) II: improving therapeutic efficacy of quercetin on oral administration. Molecular pharmaceutics\| PubMed ID: 21480639	2011
Assessment of fluidity of different invasomes by electron spin resonance and differential scanning calorimetry. International journal of pharmaceutics\| PubMed ID: 21527323	2011
Fast high-throughput screening of temoporfin-loaded liposomal formulations prepared by ethanol injection method. Journal of liposome research\| PubMed ID: 21682653	2012
[Non-viral gene transfer medicinal products. Therapy with synthetic vectors]. Pharmazie in unserer Zeit\| PubMed ID: 21698610	2011
Modeling the release kinetics of poorly water-soluble drug molecules from liposomal nanocarriers. Journal of drug delivery\| PubMed ID: 21773045	2011
Antimicrobial peptide-modified liposomes for bacteria targeted delivery of temoporfin in photodynamic antimicrobial chemotherapy. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology\| PubMed ID: 21773628	2011
Spontaneous crowding of ribosomes and proteins inside vesicles: a possible mechanism for the origin of cell metabolism. Chembiochem : a European journal of chemical biology\| PubMed ID: 21830290	2011
Wheat germ agglutinin modified liposomes for the photodynamic inactivation of bacteria. Photochemistry and photobiology\| PubMed ID: 21834868	2012
Drug delivery strategies for poorly water-soluble drugs: the industrial perspective. Expert opinion on drug delivery\| PubMed ID: 21895540	2011
Lecithin-based novel cationic nanocarriers (LeciPlex) I: fabrication, characterization and evaluation. Nanomedicine (London, England)\| PubMed ID: 22026377	2011
Interfacial concentrations of chloride and bromide in zwitterionic micelles with opposite dipoles: experimental determination by chemical trapping and a theoretical description. Journal of colloid and interface science\| PubMed ID: 22305573	2012
Human skin permeation of neutral species and ionic species: extended linear free-energy relationship analyses. Journal of pharmaceutical sciences\| PubMed ID: 22415339	2012
Selective partitioning of cholesterol and a model drug into liposomes of varying size. Chemistry and physics of lipids\| PubMed ID: 22534024	2012
Liposomes in topical photodynamic therapy. Expert opinion on drug delivery\| PubMed ID: 22731896	2012
Elastic vesicles for transdermal drug delivery of hydrophilic drugs: a comparison of important physicochemical characteristics of different vesicle types. Journal of biomedical nanotechnology\| PubMed ID: 22852471	2012
Analysis of liposomes using asymmetrical flow field-flow fractionation: separation conditions and drug/lipid recovery. Journal of separation science\| PubMed ID: 22865761	2012
Degradation kinetics of an aspartyl-tripeptide-derived diketopiperazine under forced conditions. Journal of pharmaceutical sciences\| PubMed ID: 22899465	2012
Encapsulation of ferritin, ribosomes, and ribo-peptidic complexes inside liposomes: insights into the origin of metabolism. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life\| PubMed ID: 23080007	2012
Pharmacokinetics of temoporfin-loaded liposome formulations: correlation of liposome and temoporfin blood concentration. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 23313962	2013
Transfer of a lipophilic drug (temoporfin) between small unilamellar liposomes and human plasma proteins: influence of membrane composition on vesicle integrity and release characteristics. Journal of liposome research\| PubMed ID: 23590339	2013
Liposomal encapsulation of a near-infrared fluorophore enhances fluorescence quenching and reliable whole body optical imaging upon activation in vivo. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 23650267	2013
Analysis of immobilized artificial membrane retention factors for both neutral and ionic species. Journal of chromatography. A\| PubMed ID: 23726245	2013
Non-invasive depth profile imaging of the stratum corneum using confocal Raman microscopy: first insights into the method. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 23764946	2013
Comparative SAXS and DSC study on stratum corneum structural organization in an epidermal cell culture model (ROC): impact of cultivation time. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 23770376	2013
Lipid colloidal carriers for improvement of anticancer activity of orally delivered quercetin: formulation, characterization and establishing in vitro-in vivo advantage. Journal of biomedical nanotechnology\| PubMed ID: 23909137	2013
Novel insights into appropriate encapsulation methods for bioactive compounds into polymers: a study with peptides and HDAC inhibitors. Macromolecular bioscience\| PubMed ID: 23966296	2014
[FeFe]-hydrogenase models assembled into vesicular structures. Journal of liposome research\| PubMed ID: 24006843	2014
A remarkable self-organization process as the origin of primitive functional cells. Angewandte Chemie (International ed. in English)\| PubMed ID: 24130192	2013
Influence of massage and occlusion on the ex vivo skin penetration of rigid liposomes and invasomes. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 24252713	2014
Study of pK values and effective dielectric constants of ionizable residues in pentapeptides and in staphylococcal nuclease (SNase) using a mean-field approach. The journal of physical chemistry. B\| PubMed ID: 24708515	2014
Asymmetric flow field-flow fractionation in the field of nanomedicine. Analytical chemistry\| PubMed ID: 24802650	2014
In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-immunoliposomes. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 24810115	2014
Photodynamic killing of Enterococcus faecalis in dentinal tubules using mTHPC incorporated in liposomes and invasomes. Clinical oral investigations\| PubMed ID: 24950607	2014
Electron microscopy and theoretical modeling of cochleates. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 25318049	2014
Spontaneous encapsulation and concentration of biological macromolecules in liposomes: an intriguing phenomenon and its relevance in origins of life. Journal of molecular evolution\| PubMed ID: 25416509	2014