Eric S. Lander

Eric S. Lander

Broad Institute of Harvard and Massachusetts Institute of Technology

Affiliated withBroad Institute of Harvard and Massachusetts Institute of TechnologyHarvard Medical SchoolMassachusetts Institute of Technology

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1
Year
Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
Publication title

Cited by 504

2010

Other Publications

Article
Year
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia.

Nature genetics| PubMed ID: 11731795

2002
ARACHNE: a whole-genome shotgun assembler.

Genome research| PubMed ID: 11779843

2002
2002
Human macrophage activation programs induced by bacterial pathogens.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 11805289

2002
2002
On the sequencing of the human genome.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 11880605

2002
The structure of haplotype blocks in the human genome.

Science (New York, N.Y.)| PubMed ID: 12029063

2002
2002
2002
2002
2002
Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 12235366

2002
2002
Detection of regulatory variation in mouse genes.

Nature genetics| PubMed ID: 12410233

2002
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 12438646

2002
2002
2002
2002
2003
2003
2003
Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 12529507

2003
More on the sequencing of the human genome.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 12631699

2003
2003
2003
2003
2003
2003
2003
An integrated haplotype map of the human major histocompatibility complex.

American journal of human genetics| PubMed ID: 12920676

2003
2003
2003
2003
2004
2004
2004
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 15100410

2004
2004
2004
Methods in comparative genomics: genome correspondence, gene identification and regulatory motif discovery.

Journal of computational biology : a journal of computational molecular cell biology| PubMed ID: 15285895

2004
2004
2004
Eric S. Lander.

Nature reviews. Drug discovery| PubMed ID: 15368656

2004
2005
2004
2004
2004
2005
2005
2005
An initial strategy for the systematic identification of functional elements in the human genome by low-redundancy comparative sequencing.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 15778292

2005
2005
A high-density screen for linkage in multiple sclerosis.

American journal of human genetics| PubMed ID: 16080120

2005
2005
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16199517

2005
2005
The case for selection at CCR5-Delta32.

PLoS biology| PubMed ID: 16248677

2005
2005
2006
2006
A large family of ancient repeat elements in the human genome is under strong selection.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16477033

2006
2006
2006
2006
2006
2006
2006
2006
2006
A family of conserved noncoding elements derived from an ancient transposable element.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16864796

2006
2006
2006
2006
2006
2006
2007
2007
The mammalian epigenome.

Cell| PubMed ID: 17320505

2007
2007
Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 17442748

2007
2007
2007
2007
2007
2007
Risk alleles for multiple sclerosis identified by a genomewide study.

The New England journal of medicine| PubMed ID: 17660530

2007
2007
2007
2007
2007
2007
Distinguishing protein-coding and noncoding genes in the human genome.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 18040051

2007
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 18077431

2007
2008
2008
2008
2008
2008
2008
2008
Genetic mapping in human disease.

Science (New York, N.Y.)| PubMed ID: 18988837

2008
2008
2009
Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19066216

2008
2008
2009
Highly parallel identification of essential genes in cancer cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19091943

2008
2009
2009
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19571010

2009
2009
2009
2009
2009
2009
2009
2010
2010
2010
Genetic resistance to diet-induced obesity in chromosome substitution strains of mice.

Mammalian genome : official journal of the International Mammalian Genome Society| PubMed ID: 20127486

2010
2010
Integrative analysis of the melanoma transcriptome.

Genome research| PubMed ID: 20179022

2010
2010
2010
A draft sequence of the Neandertal genome.

Science (New York, N.Y.)| PubMed ID: 20448178

2010
2010
2010
2010
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20713713

2010
2010
Prepare and inspire.

Science (New York, N.Y.)| PubMed ID: 20929738

2010
The NIH Roadmap Epigenomics Mapping Consortium.

Nature biotechnology| PubMed ID: 20944595

2010
2010
Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21098263

2010
High-quality draft assemblies of mammalian genomes from massively parallel sequence data.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21187386

2011
MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21205891

2011
Integrative genomics viewer.

Nature biotechnology| PubMed ID: 21221095

2011
2011
2011
2011
Genome-sequencing anniversary. The accelerator.

Science (New York, N.Y.)| PubMed ID: 21350161

2011
2011
2011
QnAs with Eric S. Lander. Interview by Prashant Nair.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21606349

2011
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21746896

2011
The mutational landscape of head and neck squamous cell carcinoma.

Science (New York, N.Y.)| PubMed ID: 21798893

2011
2011
2011
2011
2011
2011
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia.

The New England journal of medicine| PubMed ID: 22150006

2011
Detecting novel associations in large data sets.

Science (New York, N.Y.)| PubMed ID: 22174245

2011
The mystery of missing heritability: Genetic interactions create phantom heritability.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22223662

2012
Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22315421

2012