Michael R. Holbrook

Integrated Research Facility at Frederick, National Institutes of Health (NIH)

Affiliated withNational Institutes of Health (NIH)

Research Area

Biography

Michael R. Holbrook has not added Biography.
If you are Michael R. Holbrook and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 4	Year
Publication title Cited by 21	2016
Publication title Cited by 7	2016
Publication title Cited by 8	2016
Publication title Cited by 9	2016

Other Publications

Article	Year
Crystallization and preliminary X-ray diffraction analysis of Langat virus envelope protein domain III. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 12777770	2003
Analysis of the complete genome of the tick-borne flavivirus Omsk hemorrhagic fever virus. Virology\| PubMed ID: 12951023	2003
Molecular determinants of antigenicity of two subtypes of the tick-borne flavivirus Omsk haemorrhagic fever virus. The Journal of general virology\| PubMed ID: 15166446	2004
Use of a recombinant envelope protein subunit antigen for specific serological diagnosis of West Nile virus infection. Journal of clinical microbiology\| PubMed ID: 15184463	2004
Solution structure and antibody binding studies of the envelope protein domain III from the New York strain of West Nile virus. The Journal of biological chemistry\| PubMed ID: 15190071	2004
1H, 13C and 15N resonance assignments for domain III of the West Nile virus envelope protein. Journal of biomolecular NMR\| PubMed ID: 15213461	2004
Solution structure and structural dynamics of envelope protein domain III of mosquito- and tick-borne flaviviruses. Biochemistry\| PubMed ID: 15248774	2004
Use of recombinant E protein domain III-based enzyme-linked immunosorbent assays for differentiation of tick-borne encephalitis serocomplex flaviviruses from mosquito-borne flaviviruses. Journal of clinical microbiology\| PubMed ID: 15364996	2004
An animal model for the tickborne flavivirus--Omsk hemorrhagic fever virus. The Journal of infectious diseases\| PubMed ID: 15593010	2005
Yellow fever virus strains Asibi and 17D-204 infect human umbilical cord endothelial cells and induce novel changes in gene expression. Virology\| PubMed ID: 16150475	2005
Structure of the envelope protein domain III of Omsk hemorrhagic fever virus. Virology\| PubMed ID: 16647096	2006
Animal models of highly pathogenic RNA viral infections: encephalitis viruses. Antiviral research\| PubMed ID: 18031836	2008
Animal models of highly pathogenic RNA viral infections: hemorrhagic fever viruses. Antiviral research\| PubMed ID: 18036672	2008
Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/Vietnam/1203/04 (H5N1). Virology\| PubMed ID: 18234269	2008
Three-dimensional organization of Rift Valley fever virus revealed by cryoelectron tomography. Journal of virology\| PubMed ID: 18715915	2008
Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus. PLoS pathogens\| PubMed ID: 18769720	2008
Sub-genomic replicon and virus-like particles of Omsk hemorrhagic fever virus. Archives of virology\| PubMed ID: 19277843	2009
Single-particle cryo-electron microscopy of Rift Valley fever virus. Virology\| PubMed ID: 19304307	2009
Clinical evaluation of highly pathogenic tick-borne flavivirus infection in the mouse model. Journal of medical virology\| PubMed ID: 19475605	2009
Potential impact of a 2-person security rule on BioSafety Level 4 laboratory workers. Emerging infectious diseases\| PubMed ID: 19624910	2009
A catalytically and genetically optimized beta-lactamase-matrix based assay for sensitive, specific, and higher throughput analysis of native henipavirus entry characteristics. Virology journal\| PubMed ID: 19646266	2009
A complex adenovirus-vectored vaccine against Rift Valley fever virus protects mice against lethal infection in the presence of preexisting vector immunity. Clinical and vaccine immunology : CVI\| PubMed ID: 19776190	2009
Combined chloroquine and ribavirin treatment does not prevent death in a hamster model of Nipah and Hendra virus infection. The Journal of general virology\| PubMed ID: 19889926	2010
A replication-incompetent Rift Valley fever vaccine: chimeric virus-like particles protect mice and rats against lethal challenge. Virology\| PubMed ID: 19932911	2010
The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling. Journal of virology\| PubMed ID: 20106931	2010
A broad-spectrum antiviral targeting entry of enveloped viruses. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20133606	2010
gammadelta T cells promote the maturation of dendritic cells during West Nile virus infection. FEMS immunology and medical microbiology\| PubMed ID: 20337718	2010
VIPR: A probabilistic algorithm for analysis of microbial detection microarrays. BMC bioinformatics\| PubMed ID: 20646301	2010
Novel suspension cell-based vaccine production systems for Rift Valley fever virus-like particles. Journal of virological methods\| PubMed ID: 20655330	2010
Construction of an infectious cDNA clone for Omsk hemorrhagic fever virus, and characterization of mutations in NS2A and NS5. Virus research\| PubMed ID: 20817056	2011
Comparative analysis of immune responses to Russian spring-summer encephalitis and Omsk hemorrhagic fever viruses in mouse models. Virology\| PubMed ID: 20875909	2010
Identification of novel cellular targets for therapeutic intervention against Ebola virus infection by siRNA screening. Drug development research\| PubMed ID: 20930947	2009
A proposal to change existing virus species names to non-Latinized binomials. Archives of virology\| PubMed ID: 20953644	2010
Antiviral activities of ISG20 in positive-strand RNA virus infections. Virology\| PubMed ID: 21036379	2011
Ubiquitin-regulated nuclear-cytoplasmic trafficking of the Nipah virus matrix protein is important for viral budding. PLoS pathogens\| PubMed ID: 21085610	2010
T-705 (favipiravir) inhibition of arenavirus replication in cell culture. Antimicrobial agents and chemotherapy\| PubMed ID: 21115797	2011
Differential cytokine responses from primary human Kupffer cells following infection with wild-type or vaccine strain yellow fever virus. Virology\| PubMed ID: 21277609	2011
Infection of hepatocytes with 17-D vaccine-strain yellow fever virus induces a strong pro-inflammatory host response. The Journal of general virology\| PubMed ID: 21697351	2011
Inactivated or live-attenuated bivalent vaccines that confer protection against rabies and Ebola viruses. Journal of virology\| PubMed ID: 21849459	2011
Recombinant Rift Valley fever vaccines induce protective levels of antibody in baboons and resistance to lethal challenge in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21873194	2011
Chemotactic and inflammatory responses in the liver and brain are associated with pathogenesis of Rift Valley fever virus infection in the mouse. PLoS neglected tropical diseases\| PubMed ID: 22389738	2012
An assembly model of rift valley Fever virus. Frontiers in microbiology\| PubMed ID: 22837754	2012
Kyasanur forest disease. Antiviral research\| PubMed ID: 23110991	2012
Japanese Encephalitis Vaccines. Journal of bioterrorism & biodefense\| PubMed ID: 23125946	2011
Release of dengue virus genome induced by a peptide inhibitor. PloS one\| PubMed ID: 23226444	2012
Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes. Virus research\| PubMed ID: 23639427	2013
Tick-borne Encephalitis Vaccines. Journal of bioterrorism & biodefense\| PubMed ID: 23997980	2011
Interferon-β and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays. The Journal of general virology\| PubMed ID: 24323636	2014
A critical determinant of neurological disease associated with highly pathogenic tick-borne flavivirus in mice. Journal of virology\| PubMed ID: 24574402	2014
Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection. Antimicrobial agents and chemotherapy\| PubMed ID: 24841273	2014
Comparative pathogenesis of Alkhumra hemorrhagic fever and Kyasanur forest disease viruses in a mouse model. PLoS neglected tropical diseases\| PubMed ID: 24922308	2014
Animal models of viral hemorrhagic fever. Antiviral research\| PubMed ID: 25448088	2014
Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis. Antimicrobial agents and chemotherapy\| PubMed ID: 25487801	2015
Cytokine response in mouse bone marrow derived macrophages after infection with pathogenic and non-pathogenic Rift Valley fever virus. The Journal of general virology\| PubMed ID: 25759029	2015
Possible sexual transmission of Ebola virus - Liberia, 2015. MMWR. Morbidity and mortality weekly report\| PubMed ID: 25950255	2015
Inactivation and safety testing of Middle East Respiratory Syndrome Coronavirus. Journal of virological methods\| PubMed ID: 26190637	2015
Intratracheal exposure of common marmosets to MERS-CoV Jordan-n3/2012 or MERS-CoV EMC/2012 isolates does not result in lethal disease. Virology\| PubMed ID: 26342468	2015
3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012. Virology\| PubMed ID: 26828465	2016
Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. Science translational medicine\| PubMed ID: 26888429	2016
Characterization of Yellow Fever Virus Infection of Human and Non-human Primate Antigen Presenting Cells and Their Interaction with CD4+ T Cells. PLoS neglected tropical diseases\| PubMed ID: 27191161	2016