Peter B. Jahrling

Integrated Research Facility at Frederick, National Institutes of Health (NIH)

Affiliated withNational Institutes of Health (NIH)

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 4	Year
Publication title Cited by 21	2016
Publication title Cited by 7	2016
Publication title Cited by 8	2016
Publication title Cited by 9	2016

Other Publications

Article	Year
Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily. Immunology letters\| PubMed ID: 11803049	2002
Evidence against an important role for infectivity-enhancing antibodies in Ebola virus infections. Virology\| PubMed ID: 11853394	2002
Hemorrhagic fever viruses as biological weapons: medical and public health management. JAMA\| PubMed ID: 11988060	2002
Hemorrhagic fever occurs after intravenous, but not after intragastric, inoculation of rhesus macaques with lymphocytic choriomeningitis virus. Journal of medical virology\| PubMed ID: 11992578	2002
Evaluation in nonhuman primates of vaccines against Ebola virus. Emerging infectious diseases\| PubMed ID: 11996686	2002
Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody. Journal of virology\| PubMed ID: 12021376	2002
Smallpox research activities: U.S. interagency collaboration, 2001. Emerging infectious diseases\| PubMed ID: 12095449	2002
Detection of antibodies against the four subtypes of ebola virus in sera from any species using a novel antibody-phage indicator assay. Virology\| PubMed ID: 12350354	2002
Comparison of the protective efficacy of DNA and baculovirus-derived protein vaccines for EBOLA virus in guinea pigs. Virus research\| PubMed ID: 12686428	2003
Commentary on Dr. Alan zelicoff's Analysis of the Aralsk outbreak (No. 4). Critical reviews in microbiology\| PubMed ID: 12901683	2003
Real-time PCR assay to detect smallpox virus. Journal of clinical microbiology\| PubMed ID: 12904397	2003
Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates. Nature\| PubMed ID: 12904795	2003
Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14569023	2003
Detection and identification of Variola virus in fixed human tissue after prolonged archival storage. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 14631381	2004
Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection. The American journal of pathology\| PubMed ID: 14633608	2003
Pathogenesis of Ebola hemorrhagic fever in primate models: evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells. The American journal of pathology\| PubMed ID: 14633609	2003
Mechanisms underlying coagulation abnormalities in ebola hemorrhagic fever: overexpression of tissue factor in primate monocytes/macrophages is a key event. The Journal of infectious diseases\| PubMed ID: 14639531	2003
Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys. Lancet (London, England)\| PubMed ID: 14683653	2003
Towards a vaccine against Ebola virus. Expert review of vaccines\| PubMed ID: 14711361	2003
Smallpox and pan-orthopox virus detection by real-time 3'-minor groove binder TaqMan assays on the roche LightCycler and the Cepheid smart Cycler platforms. Journal of clinical microbiology\| PubMed ID: 14766823	2004
Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox. Nature\| PubMed ID: 15014500	2004
Interferon-beta 1a and SARS coronavirus replication. Emerging infectious diseases\| PubMed ID: 15030704	2004
Depletion of peripheral blood T lymphocytes and NK cells during the course of ebola hemorrhagic Fever in cynomolgus macaques. Viral immunology\| PubMed ID: 15357905	2004
Exploring the potential of variola virus infection of cynomolgus macaques as a model for human smallpox. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15477589	2004
The host response to smallpox: analysis of the gene expression program in peripheral blood cells in a nonhuman primate model. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15477590	2004
Trigger events: enviroclimatic coupling of Ebola hemorrhagic fever outbreaks. The American journal of tropical medicine and hygiene\| PubMed ID: 15569802	2004
Exotic emerging viral diseases: progress and challenges. Nature medicine\| PubMed ID: 15577929	2004
Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses. Nature medicine\| PubMed ID: 15937495	2005
Development of a new vaccine for the prevention of Lassa fever. PLoS medicine\| PubMed ID: 15971954	2005
Virulence differences between monkeypox virus isolates from West Africa and the Congo basin. Virology\| PubMed ID: 16023693	2005
Analysis of the expressed heavy chain variable-region genes of Macaca fascicularis and isolation of monoclonal antibodies specific for the Ebola virus' soluble glycoprotein. Immunogenetics\| PubMed ID: 16215733	2005
Ebola and Marburg viruses: pathogenesis and development of countermeasures. Current molecular medicine\| PubMed ID: 16375711	2005
Countermeasures to the bioterrorist threat of smallpox. Current molecular medicine\| PubMed ID: 16375715	2005
Cynomolgus macaque as an animal model for severe acute respiratory syndrome. PLoS medicine\| PubMed ID: 16605302	2006
Postexposure protection against Marburg haemorrhagic fever with recombinant vesicular stomatitis virus vectors in non-human primates: an efficacy assessment. Lancet\| PubMed ID: 16650649	2006
Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs. PLoS medicine\| PubMed ID: 16683867	2006
Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference. The Journal of infectious diseases\| PubMed ID: 16703508	2006
MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fever. Emerging infectious diseases\| PubMed ID: 16704825	2006
Viral hemorrhagic fevers. Clinics in laboratory medicine\| PubMed ID: 16815457	2006
Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys. PLoS pathogens\| PubMed ID: 17238286	2007
Panmicrobial oligonucleotide array for diagnosis of infectious diseases. Emerging infectious diseases\| PubMed ID: 17370518	2007
The temporal program of peripheral blood gene expression in the response of nonhuman primates to Ebola hemorrhagic fever. Genome biology\| PubMed ID: 17725815	2007
Dynamics of oliveros virus infection in rodents in central Argentina. Vector borne and zoonotic diseases (Larchmont, N.Y.)\| PubMed ID: 17760514	2007
Pathologic findings associated with delayed death in nonhuman primates experimentally infected with Zaire Ebola virus. The Journal of infectious diseases\| PubMed ID: 17940967	2007
Recombinant human activated protein C for the postexposure treatment of Ebola hemorrhagic fever. The Journal of infectious diseases\| PubMed ID: 17940975	2007
Ebola hemorrhagic fever: evaluation of passive immunotherapy in nonhuman primates. The Journal of infectious diseases\| PubMed ID: 17940976	2007
Framework for leadership and training of Biosafety Level 4 laboratory workers. Emerging infectious diseases\| PubMed ID: 18976549	2008
Vesicular stomatitis virus-based ebola vaccine is well-tolerated and protects immunocompromised nonhuman primates. PLoS pathogens\| PubMed ID: 19043556	2008
Potential impact of a 2-person security rule on BioSafety Level 4 laboratory workers. Emerging infectious diseases\| PubMed ID: 19624910	2009
Inhibition of monkeypox virus replication by RNA interference. Virology journal\| PubMed ID: 19889227	2009
Clarification and guidance on the proper usage of virus and virus species names. Archives of virology\| PubMed ID: 20204430	2010
Demonstration of cross-protective vaccine immunity against an emerging pathogenic Ebolavirus Species. PLoS pathogens\| PubMed ID: 20502688	2010
A proposal to change existing virus species names to non-Latinized binomials. Archives of virology\| PubMed ID: 20953644	2010
Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations. Archives of virology\| PubMed ID: 21046175	2010
Comparative analysis of monkeypox virus infection of cynomolgus macaques by the intravenous or intrabronchial inoculation route. Journal of virology\| PubMed ID: 21147922	2011
Crimean-Congo hemorrhagic fever: current and future prospects of vaccines and therapies. Antiviral research\| PubMed ID: 21362441	2011
Molecular imaging of influenza and other emerging respiratory viral infections. The Journal of infectious diseases\| PubMed ID: 21422476	2011
Development and characterization of rabbit and mouse antibodies against ebolavirus envelope glycoproteins. Journal of virological methods\| PubMed ID: 21513741	2011
Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry. Journal of virology\| PubMed ID: 21697477	2011
Cowpox virus infection of cynomolgus macaques as a model of hemorrhagic smallpox. Virology\| PubMed ID: 21840027	2011
Inactivated or live-attenuated bivalent vaccines that confer protection against rabies and Ebola viruses. Journal of virology\| PubMed ID: 21849459	2011
CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates. Nature medicine\| PubMed ID: 21857654	2011
Intrabronchial inoculation of cynomolgus macaques with cowpox virus. The Journal of general virology\| PubMed ID: 21940414	2012
Progression of pathogenic events in cynomolgus macaques infected with variola virus. PloS one\| PubMed ID: 21998632	2011
Evaluation of monkeypox disease progression by molecular imaging. The Journal of infectious diseases\| PubMed ID: 22013221	2011
Simian hemorrhagic fever virus infection of rhesus macaques as a model of viral hemorrhagic fever: clinical characterization and risk factors for severe disease. Virology\| PubMed ID: 22014505	2011
Evaluation of perceived threat differences posed by filovirus variants. Biosecurity and bioterrorism : biodefense strategy, practice, and science\| PubMed ID: 22070137	2011
Inhibition of cowpox virus and monkeypox virus infection by mitoxantrone. Antiviral research\| PubMed ID: 22182595	2012
Systems kinomics demonstrates Congo Basin monkeypox virus infection selectively modulates host cell signaling responses as compared to West African monkeypox virus. Molecular & cellular proteomics : MCP\| PubMed ID: 22205724	2012
Antiviral activity of the EB peptide against zoonotic poxviruses. Virology journal\| PubMed ID: 22225618	2012
Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses. Expert opinion on drug discovery\| PubMed ID: 22607481	2012
Further characterization of the immune response in mice to inactivated and live rabies vaccines expressing Ebola virus glycoprotein. Vaccine\| PubMed ID: 22884661	2012
A replication-deficient rabies virus vaccine expressing Ebola virus glycoprotein is highly attenuated for neurovirulence. Virology\| PubMed ID: 22889613	2012
The International Code of Virus Classification and Nomenclature (ICVCN): proposal to delete Rule 3.41. Archives of virology\| PubMed ID: 22932924	2013
Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae. Archives of virology\| PubMed ID: 23001720	2013
Clinical management of filovirus-infected patients. Viruses\| PubMed ID: 23170178	2012
Ebola virus genome plasticity as a marker of its passaging history: a comparison of in vitro passaging to non-human primate infection. PloS one\| PubMed ID: 23209706	2012
Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae. Archives of virology\| PubMed ID: 23358612	2013
The International Code of Virus Classification and Nomenclature (ICVCN): proposal for text changes for improved differentiation of viral taxa and viruses. Archives of virology\| PubMed ID: 23417351	2013
Poxvirus antigen staining of immune cells as a biomarker to predict disease outcome in monkeypox and cowpox virus infection in non-human primates. PloS one\| PubMed ID: 23577120	2013
Nyamiviridae: proposal for a new family in the order Mononegavirales. Archives of virology\| PubMed ID: 23636404	2013
Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system. PLoS pathogens\| PubMed ID: 23874198	2013
Nonhuman transferrin receptor 1 is an efficient cell entry receptor for Ocozocoautla de Espinosa virus. Journal of virology\| PubMed ID: 24109228	2013
Monkeypox virus infection of rhesus macaques induces massive expansion of natural killer cells but suppresses natural killer cell functions. PloS one\| PubMed ID: 24147080	2013
Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA. Archives of virology\| PubMed ID: 24190508	2014
Characterizing monkeypox virus specific CD8+ T cell epitopes in rhesus macaques. Virology\| PubMed ID: 24210113	2013
Interferon-β and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays. The Journal of general virology\| PubMed ID: 24323636	2014
ABSL-4 aerobiology biosafety and technology at the NIH/NIAID integrated research facility at Fort Detrick. Viruses\| PubMed ID: 24402304	2014
Systems kinomics for characterizing host responses to high-consequence pathogens at the NIH/NIAID Integrated Research Facility-Frederick. Pathogens and disease\| PubMed ID: 24585711	2014
The NIAID Integrated Research Facility at Frederick, Maryland: a unique international resource to facilitate medical countermeasure development for BSL-4 pathogens. Pathogens and disease\| PubMed ID: 24687975	2014
Variola virus archives: a new century, a new approach. Lancet (London, England)\| PubMed ID: 24792843	2014
Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection. Antimicrobial agents and chemotherapy\| PubMed ID: 24841273	2014
Ebola virus modulates transforming growth factor β signaling and cellular markers of mesenchyme-like transition in hepatocytes. Journal of virology\| PubMed ID: 24942569	2014
Two novel simian arteriviruses in captive and wild baboons (Papio spp.). Journal of virology\| PubMed ID: 25187550	2014
Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names. Viruses\| PubMed ID: 25256396	2014
Genome Sequences of Simian Hemorrhagic Fever Virus Variant NIH LVR42-0/M6941 Isolates (Arteriviridae: Arterivirus). Genome announcements\| PubMed ID: 25301647	2014
Simian hemorrhagic fever virus cell entry is dependent on CD163 and uses a clathrin-mediated endocytosis-like pathway. Journal of virology\| PubMed ID: 25355889	2015
CD26/DPP4 cell-surface expression in bat cells correlates with bat cell susceptibility to Middle East respiratory syndrome coronavirus (MERS-CoV) infection and evolution of persistent infect... PloS one\| PubMed ID: 25409519	2014
Reidentification of Ebola Virus E718 and ME as Ebola Virus/H.sapiens-tc/COD/1976/Yambuku-Ecran. Genome announcements\| PubMed ID: 25414499	2014
Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014. Viruses\| PubMed ID: 25421896	2014
Taxonomic reorganization of the family Bornaviridae. Archives of virology\| PubMed ID: 25449305	2015
Controlled viral glycoprotein expression as a safety feature in a bivalent rabies-ebola vaccine. Virus research\| PubMed ID: 25481284	2015
Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis. Antimicrobial agents and chemotherapy\| PubMed ID: 25487801	2015
Characterization of the host response to pichinde virus infection in the Syrian golden hamster by species-specific kinome analysis. Molecular & cellular proteomics : MCP\| PubMed ID: 25573744	2015
Lack of effect of lamivudine on Ebola virus replication. Emerging infectious diseases\| PubMed ID: 25695153	2015
Small particle aerosol inoculation of cowpox Brighton Red in rhesus monkeys results in a severe respiratory disease. Virology\| PubMed ID: 25776759	2015
Middle East respiratory syndrome: obstacles and prospects for vaccine development. Expert review of vaccines\| PubMed ID: 25864502	2015
State-of-the-Art Workshops on Medical Countermeasures Potentially Available for Human Use Following Accidental Exposures to Ebola Virus. The Journal of infectious diseases\| PubMed ID: 25957962	2015
Generation and characterization of large-particle aerosols using a center flow tangential aerosol generator with a non-human-primate, head-only aerosol chamber. Inhalation toxicology\| PubMed ID: 25970823	2015
Historical Outbreaks of Simian Hemorrhagic Fever in Captive Macaques Were Caused by Distinct Arteriviruses. Journal of virology\| PubMed ID: 25972539	2015
The effect of volume of interest definition on quantification of lymph node immune response to a monkeypox virus infection assessed by (18)F-FDG-PET. EJNMMI research\| PubMed ID: 26116113	2014
Inactivation and safety testing of Middle East Respiratory Syndrome Coronavirus. Journal of virological methods\| PubMed ID: 26190637	2015
Intratracheal exposure of common marmosets to MERS-CoV Jordan-n3/2012 or MERS-CoV EMC/2012 isolates does not result in lethal disease. Virology\| PubMed ID: 26342468	2015
Use of Existing Diagnostic Reverse-Transcription Polymerase Chain Reaction Assays for Detection of Ebola Virus RNA in Semen. The Journal of infectious diseases\| PubMed ID: 26374912	2016
Modeling [(18)F]-FDG lymphoid tissue kinetics to characterize nonhuman primate immune response to Middle East respiratory syndrome-coronavirus aerosol challenge. EJNMMI research\| PubMed ID: 26573211	2015
Reorganization and expansion of the nidoviral family Arteriviridae. Archives of virology\| PubMed ID: 26608064	2016
3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012. Virology\| PubMed ID: 26828465	2016
Divergent Simian Arteriviruses Cause Simian Hemorrhagic Fever of Differing Severities in Macaques. mBio\| PubMed ID: 26908578	2016
Influenza A and methicillin-resistant Staphylococcus aureus co-infection in rhesus macaques - A model of severe pneumonia. Antiviral research\| PubMed ID: 26923881	2016
Specific Detection of Two Divergent Simian Arteriviruses Using RNAscope In Situ Hybridization. PloS one\| PubMed ID: 26963736	2016
Ebola virus disease candidate vaccines under evaluation in clinical trials. Expert review of vaccines\| PubMed ID: 27160784	2016
Exposure of rhesus monkeys to cowpox virus Brighton Red by large-particle aerosol droplets results in an upper respiratory tract disease. The Journal of general virology\| PubMed ID: 27166137	2016
Characterization of Yellow Fever Virus Infection of Human and Non-human Primate Antigen Presenting Cells and Their Interaction with CD4+ T Cells. PLoS neglected tropical diseases\| PubMed ID: 27191161	2016
Development, Evaluation, and Integration of a Quantitative Reverse-Transcription Polymerase Chain Reaction Diagnostic Test for Ebola Virus on a Molecular Diagnostics Platform. The Journal of infectious diseases\| PubMed ID: 27247341	2016
Neglected filoviruses. FEMS microbiology reviews\| PubMed ID: 27268907	2016
Genomic Characterization of the Genus Nairovirus (Family Bunyaviridae). Viruses\| PubMed ID: 27294949	2016
Essentials of filoviral load quantification. The Lancet. Infectious diseases\| PubMed ID: 27296694	2016
Reduced evolutionary rate in reemerged Ebola virus transmission chains. Science advances\| PubMed ID: 27386513	2016
An Inactivated Rabies Virus-Based Ebola Vaccine, FILORAB1, Adjuvanted With Glucopyranosyl Lipid A in Stable Emulsion Confers Complete Protection in Nonhuman Primate Challenge Models. The Journal of infectious diseases\| PubMed ID: 27456709	2016
Overlooking the importance of immunoassays - Authors' reply. The Lancet. Infectious diseases\| PubMed ID: 27676345	2016