Stephanie W. Watts

Department of Pharmacology and Toxicology, Michigan State University

Affiliated withMichigan State University

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 68	2015
Publication title Cited by 5	2017

Other Publications

Article	Year
Upregulation of arterial serotonin 1B and 2B receptors in deoxycorticosterone acetate-salt hypertension. Hypertension\| PubMed ID: 11882579	2002
Serotonin-induced contraction in mesenteric resistance arteries: signaling and changes in deoxycorticosterone acetate-salt hypertension. Hypertension\| PubMed ID: 11897772	2002
Endothelin receptor function in mesenteric veins from deoxycorticosterone acetate salt-hypertensive rats. Journal of hypertension\| PubMed ID: 11910302	2002
Endothelin-1-induced venous contraction is maintained in DOCA-salt hypertension; studies with receptor agonists. British journal of pharmacology\| PubMed ID: 12183332	2002
Phosphoinositide 3-kinase mediates enhanced spontaneous and agonist-induced contraction in aorta of deoxycorticosterone acetate-salt hypertensive rats. Circulation research\| PubMed ID: 12193470	2002
5-Hydroxytryptamine(2B) receptor function is enhanced in the N(omega)-nitro-L-arginine hypertensive rat. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 12235249	2002
Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension. Circulation\| PubMed ID: 12600921	2003
PI3-kinase-induced hyperreactivity in DOCA-salt hypertension is independent of GSK-3 activity. Hypertension\| PubMed ID: 12629035	2003
NADPH oxidase-derived superoxide augments endothelin-1-induced venoconstriction in mineralocorticoid hypertension. Hypertension\| PubMed ID: 12885792	2003
Arterial expression of 5-HT2B and 5-HT1B receptors during development of DOCA-salt hypertension. BMC pharmacology\| PubMed ID: 12974983	2003
Low [Mg2+]e enhances arterial spontaneous tone via phosphatidylinositol 3-kinase in DOCA-salt hypertension. Hypertension\| PubMed ID: 14638620	2004
Characterization of the contractile 5-hydroxytryptamine receptor in the renal artery of the normotensive rat. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 14724222	2004
The fenfluramine metabolite (+)-norfenfluramine is vasoactive. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 14752059	2004
Rho/Rho kinase and phosphoinositide 3-kinase are parallel pathways in the development of spontaneous arterial tone in deoxycorticosterone acetate-salt hypertension. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 14982964	2004
PI3-kinase upregulation and involvement in spontaneous tone in arteries from DOCA-salt rats: is p110delta the culprit? Hypertension\| PubMed ID: 14993194	2004
Increased O2*- production and upregulation of ETB receptors by sympathetic neurons in DOCA-salt hypertensive rats. Hypertension\| PubMed ID: 15051669	2004
Arteries and veins desensitize differently to endothelin. Journal of cardiovascular pharmacology\| PubMed ID: 15076222	2004
Increased vascular sensitivity and connexin43 expression after sympathetic denervation. Cardiovascular research\| PubMed ID: 15094358	2004
C3 or not C3: that is the question. Hypertension\| PubMed ID: 15123574	2004
The serotonin transporter is present and functional in peripheral arterial smooth muscle. Journal of cardiovascular pharmacology\| PubMed ID: 15167270	2004
Effects of PPAR-gamma ligands on vascular smooth muscle marker expression in hypertensive and normal arteries. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15345487	2005
Endothelin in the splanchnic vascular bed of DOCA-salt hypertensive rats. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15471983	2005
Preserving and promoting our discipline: pharmacology students speak out. Molecular interventions\| PubMed ID: 15731498	2005
5-HT in systemic hypertension: foe, friend or fantasy? Clinical science (London, England : 1979)\| PubMed ID: 15831089	2005
(+)-Norfenfluramine-induced arterial contraction is not dependent on endogenous 5-hydroxytryptamine or 5-hydroxytryptamine transporter. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 15901794	2005
Endothelin-1-induced contraction in veins is independent of hydrogen peroxide. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15908460	2005
Upregulated function of phosphatidylinositol-3-kinase in genetically hypertensive rats: a moderator of arterial hypercontractility. Clinical and experimental pharmacology & physiology\| PubMed ID: 16173947	2005
Activation of vascular BK channel by tempol in DOCA-salt hypertensive rats. Hypertension\| PubMed ID: 16216988	2005
Vasoconstriction caused by the ATP synthase subunit-coupling factor 6: a new function for a historical enzyme. Hypertension\| PubMed ID: 16230522	2005
Pleiotropic effects of hydrogen peroxide in arteries and veins from normotensive and hypertensive rats. Hypertension\| PubMed ID: 16432037	2006
Arterial 5-hydroxytryptamine transporter function is impaired in deoxycorticosterone acetate and Nomega-nitro-L-arginine but not spontaneously hypertensive rats. Hypertension\| PubMed ID: 16754787	2006
5-hydroxytryptamine in the cardiovascular system: focus on the serotonin transporter (SERT). Clinical and experimental pharmacology & physiology\| PubMed ID: 16789923	2006
Mechanisms of hypertension induced by nitric oxide (NO) deficiency: focus on venous function. Journal of cardiovascular pharmacology\| PubMed ID: 16810074	2006
A new signaling paradigm for serotonin: use of Crk-associated substrate in arterial contraction. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16861698	2006
Cyclooxygenase, p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase MAPK, Rho kinase, and Src mediate hydrogen peroxide-induced contraction of rat thoracic aor... The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17003231	2007
A comparison of arteries and veins in oxidative stress: producers, destroyers, function, and disease. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 17202583	2007
Morphological and biochemical characterization of remodeling in aorta and vena cava of DOCA-salt hypertensive rats. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17237246	2007
The 5-hydroxytryptamine2A receptor is involved in (+)-norfenfluramine-induced arterial contraction and blood pressure increase in deoxycorticosterone acetate-salt hypertension. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17289838	2007
Preferential myosin heavy chain isoform B Expression may contribute to the faster velocity of contraction in veins versus arteries. Journal of vascular research\| PubMed ID: 17377397	2007
Methyl-beta-cyclodextrin prevents angiotensin II-induced tachyphylactic contractile responses in rat aorta. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17636007	2007
Serotonin (5-HT) in veins: not all in vain. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17671100	2007
The cytochrome p450 inhibitor ketoconazole potentiates 5-hydroxytryptamine-induced contraction in rat aorta. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17687070	2007
Big ET-1 processing into vasoactive peptides in arteries and veins. Vascular pharmacology\| PubMed ID: 17904426	2007
Vascular reactivity, 5-HT uptake, and blood pressure in the serotonin transporter knockout rat. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 18263707	2008
Role of redox signaling and poly (adenosine diphosphate-ribose) polymerase activation in vascular smooth muscle cell growth inhibition by nitric oxide and peroxynitrite. Journal of vascular surgery\| PubMed ID: 18295111	2008
5-Hydroxytryptamine lowers blood pressure in normotensive and hypertensive rats. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 18305011	2008
A serotonergic system in veins: serotonin transporter-independent uptake. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 18322152	2008
Pharmacological endothelin receptor interaction does not occur in veins from ET(B) receptor deficient rats. Vascular pharmacology\| PubMed ID: 18485831	2008
Lack of the serotonin transporter does not prevent mineralocorticoid hypertension in rat and mouse. European journal of pharmacology\| PubMed ID: 18573249	2008
A comparison of reactive oxygen species metabolism in the rat aorta and vena cava: focus on xanthine oxidase. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 18660442	2008
The love of a lifetime: 5-HT in the cardiovascular system. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 18753260	2009
The beginning of a fantastic, unanswered question: is 5-HT involved in systemic hypertension? American journal of physiology. Heart and circulatory physiology\| PubMed ID: 18775854	2008
Body distribution of infused serotonin in rats. Clinical and experimental pharmacology & physiology\| PubMed ID: 19207716	2009
Endothelin ET(B) receptors in arteries and veins: multiple actions in the vein. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 19297422	2009
Serotonylation of vascular proteins important to contraction. PloS one\| PubMed ID: 19479059	2009
Differential expression of pancreatitis-associated protein and thrombospondins in arterial versus venous tissues. Journal of vascular research\| PubMed ID: 19571575	2009
Endothelin receptors: what's new and what do we need to know? American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 19907001	2010
Uric acid does not affect the acetylcholine-induced relaxation of aorta from normotensive and deoxycorticosterone acetate-salt hypertensive rats. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 20215410	2010
Whole grape intake impacts cardiac peroxisome proliferator-activated receptor and nuclear factor kappaB activity and cytokine expression in rats with diastolic dysfunction. Hypertension\| PubMed ID: 20231522	2010
Serotonin receptors in rat jugular vein: presence and involvement in the contraction. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 20378714	2010
5-hydroxtryptamine receptors in systemic hypertension: an arterial focus. Cardiovascular therapeutics\| PubMed ID: 20433685	2011
The interdependence of endothelin-1 and calcium: a review. Clinical science (London, England : 1979)\| PubMed ID: 20662769	2010
Allopurinol does not decrease blood pressure or prevent the development of hypertension in the deoxycorticosterone acetate-salt rat model. Journal of cardiovascular pharmacology\| PubMed ID: 20881613	2010
Serotonin transporter interacts with the PDGFβ receptor in PDGF-BB-induced signaling and mitogenesis in pulmonary artery smooth muscle cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 21186266	2011
Comparison of the function of the serotonin transporter in the vasculature of male and female rats. Clinical and experimental pharmacology & physiology\| PubMed ID: 21371073	2011
Characterization of vabicaserin (SCA-136), a selective 5-hydroxytryptamine 2C receptor agonist. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 21402690	2011
Modification of proteins by norepinephrine is important for vascular contraction. Frontiers in physiology\| PubMed ID: 21423373	2010
Lack of the serotonin transporter (SERT) reduces the ability of 5-hydroxytryptamine to lower blood pressure. Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 21448568	2011
Indoleamine 2,3-diooxygenase in periaortic fat: mechanisms of inhibition of contraction. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 21841011	2011
Drug Delivery: Enabling Technology for Drug Discovery and Development. iPRECIO Micro Infusion Pump: Programmable, Refillable, and Implantable. Frontiers in pharmacology\| PubMed ID: 21863140	2011
Vena Cava and Aortic Smooth Muscle Cells Express Transglutaminases 1 and 4 in addition to Transglutaminase 2. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 22307675	2012
Smooth muscle pharmacology in the isolated virgin and pregnant rat uterus and cervix. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 22366660	2012
Serotonin and blood pressure regulation. Pharmacological reviews\| PubMed ID: 22407614	2012
5-hydroxytryptamine (5-HT) reduces total peripheral resistance during chronic infusion: direct arterial mesenteric relaxation is not involved. BMC pharmacology\| PubMed ID: 22559843	2012
Reverse-mode Na+/Ca2+ exchange is an important mediator of venous contraction. Pharmacological research : the official journal of the Italian Pharmacological Society\| PubMed ID: 22974823	2012
One-Month Serotonin Infusion Results in a Prolonged Fall in Blood Pressure in the Deoxycorticosterone Acetate (DOCA) Salt Hypertensive Rat. ACS chemical neuroscience\| PubMed ID: 23336053	2013
Long-Term Inhibition of Xanthine Oxidase by Febuxostat Does Not Decrease Blood Pressure in Deoxycorticosterone Acetate (DOCA)-Salt Hypertensive Rats. PloS one\| PubMed ID: 23393607	2013
Chemerin connects fat to arterial contraction. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 23559624	2013
Divergent signaling mechanisms for venous versus arterial contraction as revealed by endothelin-1. Journal of vascular surgery\| PubMed ID: 24726828	2014
The persistence of active smooth muscle in the female rat cervix through pregnancy. American journal of obstetrics and gynecology\| PubMed ID: 25108144	2014
Serotonin and sensory nerves: meeting in the cardiovascular system. Vascular pharmacology\| PubMed ID: 25181552	2014
Elimination of vitamin D receptor in vascular endothelial cells alters vascular function. Hypertension\| PubMed ID: 25201890	2014
Tissue transglutaminase promotes serotonin-induced AKT signaling and mitogenesis in pulmonary vascular smooth muscle cells. Cellular signalling\| PubMed ID: 25218191	2014
Transglutaminase activity is decreased in large arteries from hypertensive rats compared with normotensive controls. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 25599570	2015
5-HT is a potent relaxant in rat superior mesenteric veins. Pharmacology research & perspectives\| PubMed ID: 25692021	2015
5-Hydroxytryptamine does not reduce sympathetic nerve activity or neuroeffector function in the splanchnic circulation. European journal of pharmacology\| PubMed ID: 25732865	2015
Trash Talk by Fat: Chemerin as a Reactive Oxygen Species Provocateur in the Vasculature. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 26150433	2015
Chemerin: A comprehensive review elucidating the need for cardiovascular research. Pharmacological research\| PubMed ID: 26211950	2015
An immunohistochemical analysis of SERT in the blood-brain barrier of the male rat brain. Histochemistry and cell biology\| PubMed ID: 26223876	2015
Organic cation transporter 3 contributes to norepinephrine uptake into perivascular adipose tissue. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26432838	2015
Introducing a checklist for manuscript submission to Pharmacological Research. Pharmacological research\| PubMed ID: 26523875	2015
Pharmacological research and precision cancer medicine: A call for manuscripts. Pharmacological research\| PubMed ID: 26542638	2015
Serial Measurements of Splanchnic Vein Diameters in Rats Using High-Frequency Ultrasound. Frontiers in pharmacology\| PubMed ID: 27199758	2016
The adipokine chemerin amplifies electrical field-stimulated contraction in the isolated rat superior mesenteric artery. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 27371688	2016
Oh, the places you'll go! My many colored serotonin (apologies to Dr. Seuss). American journal of physiology. Heart and circulatory physiology\| PubMed ID: 27663771	2016
The distribution and adipogenic potential of perivascular adipose tissue adipocyte progenitors is dependent on sexual dimorphism and vessel location. Physiological reports\| PubMed ID: 27738018	2016
New actions of an old friend: perivascular adipose tissue's adrenergic mechanisms. British journal of pharmacology\| PubMed ID: 27813085	2016
Chemerin-induced arterial contraction is Gi- and calcium-dependent. Vascular pharmacology\| PubMed ID: 27890480	2017
3T3-L1 cells and perivascular adipocytes are not equivalent in amine transporter expression. FEBS letters\| PubMed ID: 27926779	2017
Regulator of G Protein Signaling 6 Protects the Heart from Ischemic Injury. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 28035008	2017
Perivascular Adipose Tissue's Impact on Norepinephrine-Induced Contraction of Mesenteric Resistance Arteries. Frontiers in physiology\| PubMed ID: 28228728	2017
5-HT causes splanchnic venodilation. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 28626072	2017