James Koropatnick

Microbiology and Immunology, Western University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2015

Other Publications

Article	Year
Reduction of copper and metallothionein in toxic milk mice by tetrathiomolybdate, but not deferiprone. Journal of inorganic biochemistry\| PubMed ID: 11803042	2002
The means to an end of tumor cell resistance to chemotherapeutic drugs targeting thymidylate synthase: shoot the messenger. Current drug targets\| PubMed ID: 12102601	2002
A sensitive time-resolved fluorescent immunoassay for metallothionein protein. Journal of immunological methods\| PubMed ID: 12505728	2003
A "combination oligonucleotide" antisense strategy to downregulate thymidylate synthase and decrease tumor cell growth and drug resistance. Cancer gene therapy\| PubMed ID: 12679800	2003
Signaling events for metallothionein induction. Mutation research\| PubMed ID: 14643422	2003
Metallothionein mediates the level and activity of nuclear factor kappa B in murine fibroblasts. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 15039454	2004
Use of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy in the treatment of locally advanced head and neck cancer patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15117987	2004
A flavonoid fraction from cranberry extract inhibits proliferation of human tumor cell lines. The Journal of nutrition\| PubMed ID: 15173424	2004
Toxicology of antisense therapeutics. Toxicology and applied pharmacology\| PubMed ID: 15519609	2004
Therapeutic potential of antisense oligodeoxynucleotides to down-regulate thymidylate synthase in mesothelioma. Molecular cancer therapeutics\| PubMed ID: 16818500	2006
Reinstalling antitumor immunity by inhibiting tumor-derived immunosuppressive molecule IDO through RNA interference. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17015752	2006
In vivo inhibition of growth of human tumor lines by flavonoid fractions from cranberry extract. Nutrition and cancer\| PubMed ID: 17176222	2006
Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells. Cancer letters\| PubMed ID: 17197076	2007
The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells. The Journal of biological chemistry\| PubMed ID: 17392272	2007
Combination silencer RNA (siRNA) targeting Bcl-2 antagonizes siRNA against thymidylate synthase in human tumor cell lines. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17452420	2007
Mouse monocytes (RAW CELLS) and the handling of cysteine and homocysteine S-conjugates of inorganic mercury and methylmercury. Journal of toxicology and environmental health. Part A\| PubMed ID: 17454556	2007
Induction of functional MT1 and MT2 isoforms by calcium in anaplastic thyroid carcinoma cells. FEBS letters\| PubMed ID: 17485079	2007
Antisense targeting of thymidylate synthase (TS) mRNA increases TS gene transcription and TS protein: effects on human tumor cell sensitivity to TS enzyme-inhibiting drugs. Gene expression\| PubMed ID: 17605297	2007
ODN 491, a novel antisense oligodeoxynucleotide that targets thymidylate synthase, exerts cell-specific effects in human tumor cell lines. DNA and cell biology\| PubMed ID: 18358073	2008
Exosomes as a tumor immune escape mechanism: possible therapeutic implications. Journal of translational medicine\| PubMed ID: 18644158	2008
Enhancement of cytotoxicity of natural product drugs against multidrug resistant variant cell lines of human head and neck squamous cell carcinoma and breast carcinoma by tesmilifene. Cancer letters\| PubMed ID: 18986763	2009
Expression of functional metallothionein isoforms in papillary thyroid cancer. Molecular and cellular endocrinology\| PubMed ID: 19356627	2009
Intravenous ascorbic acid to prevent and treat cancer-associated sepsis? Journal of translational medicine\| PubMed ID: 21375761	2011
Imaging of homeostatic, neoplastic, and injured tissues by HA-based probes. Biomacromolecules\| PubMed ID: 22066590	2012
Detection of circulating tumor cells in advanced head and neck cancer using the CellSearch system. Head & neck\| PubMed ID: 22076949	2012
Reduction of tumorigenicity by placental extracts. Anticancer research\| PubMed ID: 22493344	2012
Ki-67 expression predicts radiotherapy failure in early glottic cancer. Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale\| PubMed ID: 22569013	2012
Silencing IDO in dendritic cells: A novel approach to enhance cancer immunotherapy in a murine breast cancer model. International journal of cancer. Journal international du cancer\| PubMed ID: 22870862	2013
Frequent mutations in TP53 and CDKN2A found by next-generation sequencing of head and neck cancer cell lines. Archives of otolaryngology--head & neck surgery\| PubMed ID: 22911296	2012
A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing. ISRN oncology\| PubMed ID: 23304554	2012
Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined "Complementary Lethality". Molecular therapy. Nucleic acids\| PubMed ID: 23481354	2013
A case report and genetic characterization of a massive acinic cell carcinoma of the parotid with delayed distant metastases. Case reports in oncological medicine\| PubMed ID: 23653877	2013
Does HPV type affect outcome in oropharyngeal cancer? Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale\| PubMed ID: 23663293	2013
High frequency of activating PIK3CA mutations in human papillomavirus-positive oropharyngeal cancer. JAMA otolaryngology-- head & neck surgery\| PubMed ID: 23787421	2013
Imaging tumor growth non-invasively using expression of MagA or modified ferritin subunits to augment intracellular contrast for repetitive MRI. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 23836502	2014
Metallothionein-I- and -II-deficient mice display increased susceptibility to cadmium-induced fetal growth restriction. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 23880315	2013
Vaccinia virus outperforms a panel of other poxviruses as a potent oncolytic agent for the control of head and neck squamous cell carcinoma cell lines. Intervirology\| PubMed ID: 23942307	2014
Non-covalently functionalized single-walled carbon nanotube for topical siRNA delivery into melanoma. Biomaterials\| PubMed ID: 24424208	2014
Targeted siRNA silencing of indoleamine 2, 3-dioxygenase in antigen-presenting cells using mannose-conjugated liposomes: a novel strategy for treatment of melanoma. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 24509175	2014
Indoleamine 2,3-dioxygenase mediates immune-independent human tumor cell resistance to olaparib, gamma radiation, and cisplatin. Oncotarget\| PubMed ID: 24784564	2014
Intravenous ascorbic acid as an adjuvant to interleukin-2 immunotherapy. Journal of translational medicine\| PubMed ID: 24884532	2014
BRCA2 inhibition enhances cisplatin-mediated alterations in tumor cell proliferation, metabolism, and metastasis. Molecular oncology\| PubMed ID: 24974076	2014
Single-walled carbon nanotubes noncovalently functionalized with lipid modified polyethylenimine for siRNA delivery in vitro and in vivo. Bioconjugate chemistry\| PubMed ID: 25216445	2014