Natalie L. Trevaskis

Drug Delivery, Monash University (Parkville Campus)

Affiliated withMonash University (Parkville Campus)

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 48	2015

Other Publications

Article	Year
Profiling the Role of Deacylation-Reacylation in the Lymphatic Transport of a Triglyceride-Mimetic Prodrug. Pharmaceutical research\| PubMed ID: 25446770	2014
Bile increases intestinal lymphatic drug transport in the fasted rat. Pharmaceutical research\| PubMed ID: 16132351	2005
Tissue uptake of DDT is independent of chylomicron metabolism. Archives of toxicology\| PubMed ID: 16180009	2006
The lymph lipid precursor pool is a key determinant of intestinal lymphatic drug transport. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 16249368	2006
An examination of the interplay between enterocyte-based metabolism and lymphatic drug transport in the rat. Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 16467133	2006
An acute and coincident increase in FABP expression and lymphatic lipid and drug transport occurs during intestinal infusion of lipid-based drug formulations to rats. Pharmaceutical research\| PubMed ID: 16858652	2006
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs. Nature reviews. Drug discovery\| PubMed ID: 17330072	2007
Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update. Advanced drug delivery reviews\| PubMed ID: 18155316	2008
Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism. Pharmaceutical research\| PubMed ID: 19280324	2009
The role of the intestinal lymphatics in the absorption of two highly lipophilic cholesterol ester transfer protein inhibitors (CP524,515 and CP532,623). Pharmaceutical research\| PubMed ID: 20221896	2010
The mechanism of lymphatic access of two cholesteryl ester transfer protein inhibitors (CP524,515 and CP532,623) and evaluation of their impact on lymph lipoprotein profiles. Pharmaceutical research\| PubMed ID: 20635194	2010
Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation? Molecular pharmaceutics\| PubMed ID: 20958081	2010
Fatty acid binding proteins: potential chaperones of cytosolic drug transport in the enterocyte? Pharmaceutical research\| PubMed ID: 21523511	2011
Acute hypertriglyceridemia promotes intestinal lymphatic lipid and drug transport: a positive feedback mechanism in lipid and drug absorption. Molecular pharmaceutics\| PubMed ID: 21604764	2011
Correction to "targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?". Molecular pharmaceutics\| PubMed ID: 21995681	2011
Intravenous dosing conditions may affect systemic clearance for highly lipophilic drugs: implications for lymphatic transport and absolute bioavailability studies. Journal of pharmaceutical sciences\| PubMed ID: 22623170	2012
Strategies to address low drug solubility in discovery and development. Pharmacological reviews\| PubMed ID: 23383426	2013
A mouse model to evaluate the impact of species, sex, and lipid load on lymphatic drug transport. Pharmaceutical research\| PubMed ID: 23430484	2013
Intestinal bile secretion promotes drug absorption from lipid colloidal phases via induction of supersaturation. Molecular pharmaceutics\| PubMed ID: 23480483	2013
The impact of lymphatic transport on the systemic disposition of lipophilic drugs. Journal of pharmaceutical sciences\| PubMed ID: 23696002	2013
The potential for drug supersaturation during intestinal processing of lipid-based formulations may be enhanced for basic drugs. Molecular pharmaceutics\| PubMed ID: 23697606	2013
Lipid absorption triggers drug supersaturation at the intestinal unstirred water layer and promotes drug absorption from mixed micelles. Pharmaceutical research\| PubMed ID: 23793990	2013
Lipid-based formulations and drug supersaturation: harnessing the unique benefits of the lipid digestion/absorption pathway. Pharmaceutical research\| PubMed ID: 23824582	2013
Recent advances in lipid-based formulation technology. Pharmaceutical research\| PubMed ID: 24158727	2013
Targeted delivery of a model immunomodulator to the lymphatic system: comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 24398334	2014
In vitro-in vivo evaluation of lipid based formulations of the CETP inhibitors CP-529,414 (torcetrapib) and CP-532,623. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 25152213	2014
Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumour-burdened lymph nodes after intravenous and subcutaneous administration in rats. Molecular pharmaceutics\| PubMed ID: 25485615	2014