John H. Sampson

Duke Brain Tumor Immunotherapy Program, Duke University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 17	2015

Other Publications

Article	Year
Tumor-specific immunotherapy targeting the EGFRvIII mutation in patients with malignant glioma. Seminars in immunology\| PubMed ID: 18539480	2008
Dendritic cells pulsed with a tumor-specific peptide induce long-lasting immunity and are effective against murine intracerebral melanoma. Neurosurgery\| PubMed ID: 11844246	2002
Generation of anti-idiotypic reagents in the EGFRvIII tumor-associated antigen system. Cancer immunology, immunotherapy : CII\| PubMed ID: 11862416	2002
Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 11870184	2002
Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 11980998	2002
Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion. Cancer research\| PubMed ID: 12067969	2002
Intracanalicular meningioma mimicking vestibular schwannoma. AJNR. American journal of neuroradiology\| PubMed ID: 12372737	2002
Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa). Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 12429640	2002
Phase II trial of temozolomide in patients with progressive low-grade glioma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 12586801	2003
Viruses in the treatment of brain tumors. Neuroimaging clinics of North America\| PubMed ID: 12687911	2002
Clinical immunotherapy for brain tumors. Neuroimaging clinics of North America\| PubMed ID: 12687917	2002
The history, evolution, and clinical use of dendritic cell-based immunization strategies in the therapy of brain tumors. Journal of neuro-oncology\| PubMed ID: 12952297	2003
Adoptive immunotherapy for malignant glioma. Cancer journal (Sudbury, Mass.)\| PubMed ID: 12952301	2003
Epidermal growth factor receptor VIII peptide vaccination is efficacious against established intracerebral tumors. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 14519652	2003
Phase II trial of gefitinib in recurrent glioblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 14638850	2004
Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomon... Journal of neuro-oncology\| PubMed ID: 14649883	2003
Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 14654531	2003
Immunotherapy of surgical malignancies. Current problems in surgery\| PubMed ID: 14749625	2004
Microvascular decompression for glossopharyngeal neuralgia: long-term effectiveness and complication avoidance. Neurosurgery\| PubMed ID: 15046654	2004
Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15131063	2004
Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma. Neuro-oncology\| PubMed ID: 15134628	2004
Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma. Neuro-oncology\| PubMed ID: 15134629	2004
Treatment of intracerebral neoplasia and neoplastic meningitis with regional delivery of oncolytic recombinant poliovirus. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15269159	2004
Poliovirus receptor CD155-targeted oncolysis of glioma. Neuro-oncology\| PubMed ID: 15279713	2004
Sustained radiographic and clinical response in patient with bifrontal recurrent glioblastoma multiforme with intracerebral infusion of the recombinant targeted toxin TP-38: case study. Neuro-oncology\| PubMed ID: 15701286	2005
Surgical management of petroclival meningiomas: defining resection goals based on risk of neurological morbidity and tumor recurrence rates in 137 patients. Neurosurgery\| PubMed ID: 15730581	2005
Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 16192602	2005
Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 16361636	2005
Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16467100	2006
Targeted therapy for glioblastoma multiforme neoplastic meningitis with intrathecal delivery of an oncolytic recombinant poliovirus. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16489093	2006
Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma. Cancer research\| PubMed ID: 16540683	2006
Convection-enhanced delivery of therapeutics for brain disease, and its optimization. Neurosurgical focus\| PubMed ID: 16709017	2006
Comparison of intratumoral bolus injection and convection-enhanced delivery of radiolabeled antitenascin monoclonal antibodies. Neurosurgical focus\| PubMed ID: 16709019	2006
Safety of intraparenchymal convection-enhanced delivery of cintredekin besudotox in early-phase studies. Neurosurgical focus\| PubMed ID: 16709020	2006
Novel human IgG2b/murine chimeric antitenascin monoclonal antibody construct radiolabeled with 131I and administered into the surgically created resection cavity of patients with malignant g... Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 16741299	2006
Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16857805	2006
Preoperative functional MR imaging localization of language and motor areas: effect on therapeutic decision making in patients with potentially resectable brain tumors. Radiology\| PubMed ID: 16857981	2006
Treatment of neoplastic meningitis with intrathecal 9-nitro-camptothecin. Neurologia medico-chirurgica\| PubMed ID: 17062987	2006
Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity. Journal of neuroimmunology\| PubMed ID: 17137636	2007
Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals differential expression of the immunologic transcriptome compared with T cells from heal... Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17189402	2006
Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas. Journal of neuro-oncology\| PubMed ID: 17245623	2007
Intracerebral infusate distribution by convection-enhanced delivery in humans with malignant gliomas: descriptive effects of target anatomy and catheter positioning. Neurosurgery\| PubMed ID: 17297371	2007
Induction of hyperintense signal on T2-weighted MR images correlates with infusion distribution from intracerebral convection-enhanced delivery of a tumor-targeted cytotoxin. AJR. American journal of roentgenology\| PubMed ID: 17312057	2007
Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 17327604	2007
Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17404100	2007
Viruses in the treatment of malignant glioma. Expert review of neurotherapeutics\| PubMed ID: 17425484	2007
Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions. Neuro-oncology\| PubMed ID: 17435179	2007
EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells. Cancer immunology, immunotherapy : CII\| PubMed ID: 17634939	2008
Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma. Neuro-oncology\| PubMed ID: 17951512	2008
Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study. Neuro-oncology\| PubMed ID: 18079360	2008
Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study... Neurosurgery\| PubMed ID: 18091279	2007
Cholesterol granuloma of the lateral ventricle. Case report. Journal of neurosurgery\| PubMed ID: 18240934	2008
Immunotherapy of malignant brain tumors. Immunological reviews\| PubMed ID: 18363995	2008
Cryptococcal meningitis in patients with glioma: a report of two cases. Journal of neuro-oncology\| PubMed ID: 18398572	2008
Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors. Neuro-oncology\| PubMed ID: 18403491	2008
Selective modification of antigen-specific T cells by RNA electroporation. Human gene therapy\| PubMed ID: 18471037	2008
Immunotherapy against angiogenesis-associated targets: evidence and implications for the treatment of malignant glioma. Expert review of anticancer therapy\| PubMed ID: 18471045	2008
Combating immunosuppression in glioma. Future oncology (London, England)\| PubMed ID: 18518768	2008
Detection of humoral response in patients with glioblastoma receiving EGFRvIII-KLH vaccines. Journal of immunological methods\| PubMed ID: 18775433	2008
A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 18794085	2008
Stereotactic body radiotherapy for lesions of the spine and paraspinal regions. International journal of radiation oncology, biology, physics\| PubMed ID: 19004569	2009
Proteomic and immunologic analyses of brain tumor exosomes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 19109410	2009
Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19188181	2009
Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 19204199	2009
Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma. Neuro-oncology\| PubMed ID: 19289491	2009
Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma. Cancer\| PubMed ID: 19402172	2009
IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era. International journal of cancer. Journal international du cancer\| PubMed ID: 19408307	2009
Paraganglioma of the head and neck: long-term local control with radiotherapy. American journal of clinical oncology\| PubMed ID: 19433962	2009
A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas. Journal of neurochemistry\| PubMed ID: 19519779	2009
Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy. Journal of neuro-oncology\| PubMed ID: 19533023	2009
Toward effective immunotherapy for the treatment of malignant brain tumors. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 19560742	2009
Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma. Journal of neuro-oncology\| PubMed ID: 19562254	2010
The PEPvIII-KLH (CDX-110) vaccine in glioblastoma multiforme patients. Expert opinion on biological therapy\| PubMed ID: 19591631	2009
Treatment of HER2-positive breast carcinomatous meningitis with intrathecal administration of alpha-particle-emitting (211)At-labeled trastuzumab. Nuclear medicine and biology\| PubMed ID: 19647172	2009
EGFRvIII-targeted vaccination therapy of malignant glioma. Brain pathology (Zurich, Switzerland)\| PubMed ID: 19744042	2009
An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme. Molecular cancer therapeutics\| PubMed ID: 19825799	2009
Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1. Journal of neuro-oncology\| PubMed ID: 19898744	2010
Clinical applications of a peptide-based vaccine for glioblastoma. Neurosurgery clinics of North America\| PubMed ID: 19944970	2010
The role of tregs in glioma-mediated immunosuppression: potential target for intervention. Neurosurgery clinics of North America\| PubMed ID: 19944972	2010
Bevacizumab fails to treat temporal paraganglioma: discussion and case illustration. Journal of neuro-oncology\| PubMed ID: 20020179	2010
Poor drug distribution as a possible explanation for the results of the PRECISE trial. Journal of neurosurgery\| PubMed ID: 20020841	2010
Long-term safety of combined intracerebral delivery of free gadolinium and targeted chemotherapeutic agent PRX321. Neurological research\| PubMed ID: 20021739	2010
The role of tregs in human glioma patients and their inhibition with a novel STAT-3 inhibitor. Clinical neurosurgery\| PubMed ID: 20214040	2009
Immunotherapy approaches for malignant glioma from 2007 to 2009. Current neurology and neuroscience reports\| PubMed ID: 20424975	2010
Stereotactic radiosurgery in the treatment of a dural carotid-cavernous fistula. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society\| PubMed ID: 20431489	2010
Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma. Journal of neuro-oncology\| PubMed ID: 20443129	2011
Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study. Journal of neuro-oncology\| PubMed ID: 20563833	2011
Low-grade glioma. Journal of neurosurgery\| PubMed ID: 20635855	2011
A comprehensive outlook on intracerebral therapy of malignant gliomas. Critical reviews in oncology/hematology\| PubMed ID: 20888252	2011
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 20921459	2010
Immunotherapy coming of age: what will it take to make it standard of care for glioblastoma? Neuro-oncology\| PubMed ID: 21149252	2011
Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma. Neuro-oncology\| PubMed ID: 21149254	2011
Resection of vestibular schwannomas. Journal of neurosurgery\| PubMed ID: 21250806	2011
A novel method for volumetric MRI response assessment of enhancing brain tumors. PloS one\| PubMed ID: 21298088	2011
Clinical trial end points for high-grade glioma: the evolving landscape. Neuro-oncology\| PubMed ID: 21310734	2011
Colocalization of gadolinium-diethylene triamine pentaacetic acid with high-molecular-weight molecules after intracerebral convection-enhanced delivery in humans. Neurosurgery\| PubMed ID: 21430586	2011
Bispecific antibodies engage T cells for antitumor immunotherapy. Expert opinion on biological therapy\| PubMed ID: 21449821	2011
A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma. Journal of the National Comprehensive Cancer Network : JNCCN\| PubMed ID: 21464146	2011
Safety and efficacy of stereotactic radiosurgery and adjuvant bevacizumab in patients with recurrent malignant gliomas. International journal of radiation oncology, biology, physics\| PubMed ID: 21489708	2012
Epidemiology. Journal of neurosurgery\| PubMed ID: 21529133	2011
The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide, and irinotecan for newly diagnosed glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21531816	2011
Our failure to advance new treatments for glioma to market. Journal of neurosurgery\| PubMed ID: 21568655	2011
Phase 2 study of carboplatin, irinotecan, and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy. Cancer\| PubMed ID: 21590689	2011
Application of novel response/progression measures for surgically delivered therapies for gliomas: Response Assessment in Neuro-Oncology (RANO) Working Group. Neurosurgery\| PubMed ID: 21593697	2012
Convection-enhanced delivery. Journal of neurosurgery\| PubMed ID: 21619413	2011
Is cytomegalovirus a therapeutic target in glioblastoma? Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21632859	2011
Disparities in care. Journal of neurosurgery\| PubMed ID: 21740120	2012
Monoclonal antibody blockade of IL-2 receptor Î± during lymphopenia selectively depletes regulatory T cells in mice and humans. Blood\| PubMed ID: 21768296	2011
Bevacizumab-induced reversible posterior leukoencephalopathy syndrome and successful retreatment in a patient with glioblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 21900098	2011
Phase II study of GleevecÂ® plus hydroxyurea (HU) in adults with progressive or recurrent meningioma. Journal of neuro-oncology\| PubMed ID: 21938530	2012
Phase II study of carboplatin, irinotecan, and bevacizumab for bevacizumab naÃ¯ve, recurrent glioblastoma. Journal of neuro-oncology\| PubMed ID: 21986722	2012
Avastin: more questions than answers. . . Journal of neurosurgery\| PubMed ID: 22035270	2012
Clinical data simplified. Journal of neurosurgery\| PubMed ID: 22054209	2012
Monitoring radiographic brain tumor progression. Toxins\| PubMed ID: 22069705	2011
Imaging of convection enhanced delivery of toxins in humans. Toxins\| PubMed ID: 22069706	2011
Immunotherapy with tumor vaccines for the treatment of malignant gliomas. Current drug discovery technologies\| PubMed ID: 22339070	2012
Convection enhanced delivery of macromolecules for brain tumors. Current drug discovery technologies\| PubMed ID: 22339074	2012
A pilot study of IL-2RÎ± blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma. PloS one\| PubMed ID: 22383993	2012
Toxin-based targeted therapy for malignant brain tumors. Clinical & developmental immunology\| PubMed ID: 22400035	2012
Phase 1 trial of dasatinib plus erlotinib in adults with recurrent malignant glioma. Journal of neuro-oncology\| PubMed ID: 22407177	2012
Resection and survival. Journal of neurosurgery\| PubMed ID: 22424561	2012
The use of motor mapping to aid resection of eloquent gliomas. Neurosurgery clinics of North America\| PubMed ID: 22440865	2012
Stereotactic radiosurgery and bevacizumab for recurrent glioblastoma multiforme. Journal of the National Comprehensive Cancer Network : JNCCN\| PubMed ID: 22679114	2012
Therapeutic approaches for HER2-positive brain metastases: circumventing the blood-brain barrier. Cancer treatment reviews\| PubMed ID: 22727691	2013
Editorial: Convection-enhanced delivery. Journal of neurosurgery\| PubMed ID: 22998062	2012
Enzyme redesign guided by cancer-derived IDH1 mutations. Nature chemical biology\| PubMed ID: 23001033	2012
Contemporary surgical management of vestibular schwannomas: analysis of complications and lessons learned over the past decade. Neurosurgery\| PubMed ID: 23037828	2013
Subarachnoid hemorrhage trials. Journal of neurosurgery\| PubMed ID: 23039153	2013
Regulatory T cells move in when gliomas say "I Do". Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23052252	2012
The limitations of imaging response criteria. The Lancet. Oncology\| PubMed ID: 23116995	2012
Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23248284	2013
Thickness of subcutaneous fat as a risk factor for infection in cervical spine fusion surgery. The Journal of bone and joint surgery. American volume\| PubMed ID: 23426766	2013
Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice. PloS one\| PubMed ID: 23527092	2013
Isocitrate dehydrogenase 1: what it means to the neurosurgeon: a review. Journal of neurosurgery\| PubMed ID: 23581583	2013
BLyS levels correlate with vaccine-induced antibody titers in patients with glioblastoma lymphodepleted by therapeutic temozolomide. Cancer immunology, immunotherapy : CII\| PubMed ID: 23591978	2013
Radiotherapy and radiosurgery for tumors of the central nervous system. Surgical oncology clinics of North America\| PubMed ID: 23622073	2013
Clinicopathological characteristics and treatment of rhabdoid glioblastoma. Journal of neurosurgery\| PubMed ID: 23641829	2013
Concurrent stereotactic radiosurgery and bevacizumab in recurrent malignant gliomas: a prospective trial. International journal of radiation oncology, biology, physics\| PubMed ID: 23725997	2013
A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system. Oncoimmunology\| PubMed ID: 23734318	2013
An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma. Expert review of vaccines\| PubMed ID: 23750791	2013
Complete response to steroids in dural inflammatory pseudotumor associated with Still's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia\| PubMed ID: 23768965	2013
Rational design and generation of recombinant control reagents for bispecific antibodies through CDR mutagenesis. Journal of immunological methods\| PubMed ID: 23806556	2013
Antibody, T-cell and dendritic cell immunotherapy for malignant brain tumors. Future oncology (London, England)\| PubMed ID: 23837761	2013
An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma. Expert review of clinical pharmacology\| PubMed ID: 23927666	2013
A cytokine cocktail directly modulates the phenotype of DC-enriched anti-tumor T cells to convey potent anti-tumor activities in a murine model. Cancer immunology, immunotherapy : CII\| PubMed ID: 23982483	2013
Intracerebral delivery of a third generation EGFRvIII-specific chimeric antigen receptor is efficacious against human glioma. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia\| PubMed ID: 24054399	2014
Enhanced oncolytic virotherapy through oxidative stress inhibition. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 24201213	2013
SEER insights. Journal of neurosurgery\| PubMed ID: 24286150	2014
EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 24352643	2014
Impact of PhD training on scholarship in a neurosurgical career. Journal of neurosurgery\| PubMed ID: 24359004	2014
Editorial on "heat shock protein peptide complex-96 (HSPPC-96) vaccination for recurrent glioblastoma: a phase II, single arm trial". Neuro-oncology\| PubMed ID: 24443362	2014
Methodology and reporting of meta-analyses in the neurosurgical literature. Journal of neurosurgery\| PubMed ID: 24460491	2014
Regulatory T cells are redirected to kill glioblastoma by an EGFRvIII-targeted bispecific antibody. Oncoimmunology\| PubMed ID: 24475376	2013
Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody. Cancer immunology research\| PubMed ID: 24570975	2013
Recognition and killing of autologous, primary glioblastoma tumor cells by human cytomegalovirus pp65-specific cytotoxic T cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 24658154	2014
EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma. PloS one\| PubMed ID: 24722266	2014
Response. Journal of neurosurgery\| PubMed ID: 24724172	2014
Worse outcomes for patients undergoing brain tumor and cerebrovascular procedures following the ACGME resident duty-hour restrictions. Journal of neurosurgery\| PubMed ID: 24926647	2014
Oncolytic polio virotherapy of cancer. Cancer\| PubMed ID: 24939611	2014
A novel, reproducible, and objective method for volumetric magnetic resonance imaging assessment of enhancing glioblastoma. Journal of neurosurgery\| PubMed ID: 25036205	2014
Immunological targeting of cytomegalovirus for glioblastoma therapy. Oncoimmunology\| PubMed ID: 25101224	2014
Standard of care and future pharmacological treatment options for malignant glioma: an urgent need for screening and identification of novel tumor-specific antigens. Expert opinion on pharmacotherapy\| PubMed ID: 25139628	2014
Antibody-based immunotherapy for malignant glioma. Seminars in oncology\| PubMed ID: 25173142	2014
Rindopepimut: a promising immunotherapeutic for the treatment of glioblastoma multiforme. Immunotherapy\| PubMed ID: 25186601	2014
Immunotherapy advances for glioblastoma. Neuro-oncology\| PubMed ID: 25190673	2014
Recurrent malignant gliomas. Seminars in radiation oncology\| PubMed ID: 25219814	2014
Enhancing dendritic cell-based vaccination for highly aggressive glioblastoma. Expert opinion on biological therapy\| PubMed ID: 25327832	2015
Epidermal growth factor receptor and variant III targeted immunotherapy. Neuro-oncology\| PubMed ID: 25342601	2014
Targeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression. The Journal of clinical investigation\| PubMed ID: 25347474	2014
Severe Adverse Immunologic Reaction in a Patient with Glioblastoma Receiving Autologous Dendritic Cell Vaccines Combined with GM-CSF and Dose-Intensified Temozolomide. Cancer immunology research\| PubMed ID: 25387895	2014
Immunotherapy for primary brain tumors: no longer a matter of privilege. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 25398845	2014
Defining the Optimal Planning Target Volume in Image-Guided Stereotactic Radiosurgery of Brain Metastases: Results of a Randomized Trial. International journal of radiation oncology, biology, physics\| PubMed ID: 25442342	2014
Peptide vaccines for the treatment of glioblastoma. Journal of neuro-oncology\| PubMed ID: 25491947	2014
Increased proportion of FoxP3+ regulatory T cells in tumor infiltrating lymphocytes is associated with tumor recurrence and reduced survival in patients with glioblastoma. Cancer immunology, immunotherapy : CII\| PubMed ID: 25555571	2015
A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study. Neuro-oncology\| PubMed ID: 25586468	2015
Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: Implications for drug development. Journal of neurochemistry\| PubMed ID: 25598002	2015
Leveraging chemotherapy-induced lymphopenia to potentiate cancer immunotherapy. Oncoimmunology\| PubMed ID: 25610727	2014
Chimeric antigen receptor engineered T cells can eliminate brain tumors and initiate long-term protection against recurrence. Oncoimmunology\| PubMed ID: 25610729	2014