Scott L. Friedman

Department of Medicine, Icahn School of Medicine at Mount Sinai

Affiliated withIcahn School of Medicine at Mount Sinai Icahn School of Medicine at Mount Sinai

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 62	2015

Other Publications

Article	Year
Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression. Journal of hepatology\| PubMed ID: 15763341	2005
Lhx2-/- mice develop liver fibrosis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15536133	2004
Mac the knife? Macrophages- the double-edged sword of hepatic fibrosis. The Journal of clinical investigation\| PubMed ID: 15630440	2005
Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 15728706	2005
A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk. Cancer research\| PubMed ID: 15735005	2005
Prevention of rat hepatocarcinogenesis by acyclic retinoid is accompanied by reduction in emergence of both TGF-alpha-expressing oval-like cells and activated hepatic stellate cells. Nutrition and cancer\| PubMed ID: 15860442	2005
Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1. The Journal of biological chemistry\| PubMed ID: 15917248	2005
Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread. Cancer research\| PubMed ID: 15994951	2005
Sex steroids have differential effects on growth and gene expression in primary human prostatic epithelial cell cultures derived from the peripheral versus transition zones. Carcinogenesis\| PubMed ID: 16123118	2006
BMP-7 opposes TGF-beta1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 16126788	2006
Enhanced oral tolerance in transgenic mice with hepatocyte secretion of IL-10. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16148101	2005
Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation. Cancer research\| PubMed ID: 16230382	2005
Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6. Blood\| PubMed ID: 16234353	2006
Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications. Nature clinical practice. Gastroenterology & hepatology\| PubMed ID: 16265071	2004
Reversal of hepatic fibrosis -- fact or fantasy? Hepatology (Baltimore, Md.)\| PubMed ID: 16447275	2006
Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo. Hepatology (Baltimore, Md.)\| PubMed ID: 16496318	2006
Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC. Journal of hepatology\| PubMed ID: 16515819	2006
Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16778100	2006
Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis. British journal of pharmacology\| PubMed ID: 16783407	2006
Stellate cell apoptosis by a soluble mediator from immortalized human hepatocytes. Apoptosis : an international journal on programmed cell death\| PubMed ID: 16830231	2006
Targeted and regulable expression of transgenes in hepatic stellate cells and myofibroblasts in culture and in vivo using an adenoviral Cre/loxP system to antagonise hepatic fibrosis. Gut\| PubMed ID: 16956920	2007
Transcriptional regulation of stellate cell activation. Journal of gastroenterology and hepatology\| PubMed ID: 16958680	2006
Beneficial effect of glatiramer acetate (Copaxone) on immune modulation of experimental hepatic fibrosis. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 17038628	2007
Molecular diagnosis of chronic liver disease and hepatocellular carcinoma: the potential of gene expression profiling. Seminars in liver disease\| PubMed ID: 17051451	2006
A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis. Gastroenterology\| PubMed ID: 17087938	2006
Reefer madness? Assessing the effects of cannabinoids with a less jaundiced eye. Journal of hepatology\| PubMed ID: 17107732	2007
KLF6 degradation after apoptotic DNA damage. FEBS letters\| PubMed ID: 17113081	2006
Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats. Gut\| PubMed ID: 17127702	2007
Diagnosis of hepatic fibrosis in patients with chronic hepatitis C. Clinics in liver disease\| PubMed ID: 17164119	2006
Hepatic fibrosis 2006: report of the Third AASLD Single Topic Conference. Hepatology (Baltimore, Md.)\| PubMed ID: 17187439	2007
Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation. Journal of hepatology\| PubMed ID: 17196295	2007
Genomics and signaling pathways in hepatocellular carcinoma. Seminars in liver disease\| PubMed ID: 17295177	2007
Reversibility of hepatic fibrosis and cirrhosis--is it all hype? Nature clinical practice. Gastroenterology & hepatology\| PubMed ID: 17476207	2007
Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma. International journal of cancer. Journal international du cancer\| PubMed ID: 17514651	2007
Immunopathogenesis of hepatitis C virus infection and hepatic fibrosis: New insights into antifibrotic therapy in chronic hepatitis C. Hepatology research : the official journal of the Japan Society of Hepatology\| PubMed ID: 17517074	2007
KLF6 allelic loss is associated with tumor recurrence and markedly decreased survival in head and neck squamous cell carcinoma. International journal of cancer. Journal international du cancer\| PubMed ID: 17621627	2007
Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats. Hepatology (Baltimore, Md.)\| PubMed ID: 17935226	2007
Hepatic fibrogenesis. Seminars in liver disease\| PubMed ID: 17979077	2007
A deer in the headlights: BAMBI meets liver fibrosis. Nature medicine\| PubMed ID: 17987019	2007
Regression of fibrosis after chronic stimulation of cannabinoid CB2 receptor in cirrhotic rats. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 18029545	2008
Liver fibrosis: from mechanisms to treatment. Gastroentérologie clinique et biologique\| PubMed ID: 18166858	2007
Insulin-like growth factor-i regulates Kruppel-like factor-6 gene expression in a p53-dependent manner. Endocrinology\| PubMed ID: 18174288	2008
Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiological reviews\| PubMed ID: 18195085	2008
Experimental models of hepatocellular carcinoma. Journal of hepatology\| PubMed ID: 18314222	2008
Cannabinoids provoke alcoholic steatosis through a conspiracy of neighbors. Cell metabolism\| PubMed ID: 18316020	2008
Targeting siRNA to arrest fibrosis. Nature biotechnology\| PubMed ID: 18392021	2008
The movement of aquatic mercury through terrestrial food webs. Science (New York, N.Y.)\| PubMed ID: 18420925	2008
Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma. Gastroenterology\| PubMed ID: 18471523	2008
Mechanisms of hepatic fibrogenesis. Gastroenterology\| PubMed ID: 18471545	2008
The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease. Gastroenterology\| PubMed ID: 18515091	2008
KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis. The Journal of clinical investigation\| PubMed ID: 18596922	2008
Hepatic fibrosis -- overview. Toxicology\| PubMed ID: 18662740	2008
Future trends in hepatology: challenges and opportunities. Hepatology (Baltimore, Md.)\| PubMed ID: 18666245	2008
Increased alternative splicing of the KLF6 tumour suppressor gene correlates with prognosis and tumour grade in patients with pancreatic cancer. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 18691883	2008
Focal gains of VEGFA and molecular classification of hepatocellular carcinoma. Cancer research\| PubMed ID: 18701503	2008
Activation of hepatic stellate cells after phagocytosis of lymphocytes: A novel pathway of fibrogenesis. Hepatology (Baltimore, Md.)\| PubMed ID: 18726940	2008
p38-MAPK- and caspase-3-mediated superoxide-induced apoptosis of rat hepatic stellate cells: reversal by retinoic acid. Journal of cellular physiology\| PubMed ID: 18792915	2009
Gene expression in fixed tissues and outcome in hepatocellular carcinoma. The New England journal of medicine\| PubMed ID: 18923165	2008
Pivotal role of mTOR signaling in hepatocellular carcinoma. Gastroenterology\| PubMed ID: 18929564	2008
Preface. Hepatic fibrosis: pathogenesis, diagnosis, and emerging therapies. Clinics in liver disease\| PubMed ID: 18984462	2008
TGF-beta regulates the expression of transcription factor KLF6 and its splice variants and promotes co-operative transactivation of common target genes through a Smad3-Sp1-KLF6 interaction. The Biochemical journal\| PubMed ID: 19076057	2009
Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of Toll-like receptor 4 to hepatic stellate cell responses. Hepatology (Baltimore, Md.)\| PubMed ID: 19085953	2009
Advances in antifibrotic therapy. Expert review of gastroenterology & hepatology\| PubMed ID: 19090740	2008
Commentary: Gastroenterology and hepatology: an evolving marriage, not an imminent divorce. The American journal of gastroenterology\| PubMed ID: 19098841	2009
Functional role of the KLF6 tumour suppressor gene in gastric cancer. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 19101139	2009
PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signaling. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 19114984	2009
Detection of novel biomarkers of liver cirrhosis by proteomic analysis. Hepatology (Baltimore, Md.)\| PubMed ID: 19177598	2009
Resveratrol amplifies profibrogenic effects of free fatty acids on human hepatic stellate cells. Hepatology research : the official journal of the Japan Society of Hepatology\| PubMed ID: 19207580	2009
Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans. Gastroenterology\| PubMed ID: 19344719	2009
Hepatic fibrosis. Current opinion in gastroenterology\| PubMed ID: 19396960	2009
Detection of intracellular ADAMTS13, a secreted zinc-metalloprotease, via flow cytometry. Cytometry. Part A : the journal of the International Society for Analytical Cytology\| PubMed ID: 19526483	2009
Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection. Journal of hepatology\| PubMed ID: 19586676	2009
Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo. Journal of hepatology\| PubMed ID: 19665249	2009
Therapeutic targeting of the PDGF and TGF-beta-signaling pathways in hepatic stellate cells by PTK787/ZK22258. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 19668241	2009
Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma. Cancer research\| PubMed ID: 19723656	2009
Kupffer cell activation by ambient air particulate matter exposure may exacerbate non-alcoholic fatty liver disease. Journal of immunotoxicology\| PubMed ID: 19908945	2009
A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells. The Journal of biological chemistry\| PubMed ID: 20022962	2010
Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene. FEBS letters\| PubMed ID: 20116377	2010
Downregulation of hepatic stellate cell activation by retinol and palmitate mediated by adipose differentiation-related protein (ADRP). Journal of cellular physiology\| PubMed ID: 20143336	2010
Obesity, inflammatory signaling, and hepatocellular carcinoma-an enlarging link. Cancer cell\| PubMed ID: 20159605	2010
Klf6/copeb is required for hepatic outgrowth in zebrafish and for hepatocyte specification in mouse ES cells. Developmental biology\| PubMed ID: 20430021	2010
Loss of matrix metalloproteinase-2 amplifies murine toxin-induced liver fibrosis by upregulating collagen I expression. Digestive diseases and sciences\| PubMed ID: 20563750	2011
Evolving challenges in hepatic fibrosis. Nature reviews. Gastroenterology & hepatology\| PubMed ID: 20585339	2010
Characterization of the human Activin-A receptor type II-like kinase 1 (ACVRL1) promoter and its regulation by Sp1. BMC molecular biology\| PubMed ID: 20587022	2010
KLF6 Gene and early melanoma development in a collagen I-rich extracellular environment. Journal of the National Cancer Institute\| PubMed ID: 20660366	2010
Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation. Hepatology (Baltimore, Md.)\| PubMed ID: 20684020	2010
Reduced nicotinamide adenine dinucleotide phosphate oxidase 2 plays a key role in stellate cell activation and liver fibrogenesis in vivo. Gastroenterology\| PubMed ID: 20685364	2010
Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesis. Fibrogenesis & tissue repair\| PubMed ID: 20964825	2010
E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis. PloS one\| PubMed ID: 21049091	2010
Pathogenesis of liver fibrosis. Annual review of pathology\| PubMed ID: 21073339	2011
Fibrosis in the liver: acute protection and chronic disease. Progress in molecular biology and translational science\| PubMed ID: 21074733	2010
Platelets arrive at the scene of fibrosis……studies. Journal of hepatology\| PubMed ID: 21167890	2011
Focus. Journal of hepatology\| PubMed ID: 21232564	2011
Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib. Journal of hepatology\| PubMed ID: 21251937	2011
Dendritic cells in alcoholic liver injury and fibrosis. Alcoholism, clinical and experimental research\| PubMed ID: 21284665	2011
Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling. Fibrogenesis & tissue repair\| PubMed ID: 21288331	2011
SPARC downregulation attenuates the profibrogenic response of hepatic stellate cells induced by TGF-β1 and PDGF. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 21311029	2011
Reactive oxygen species and NADPH oxidase 4 induced by transforming growth factor β1 are the therapeutic targets of polyenylphosphatidylcholine in the suppression of human hepatic stellate c... Inflammation research : official journal of the European Histamine Research Society ... [et al.]\| PubMed ID: 21318733	2011
MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a. Gastroenterology\| PubMed ID: 21324318	2011
Mechanisms of liver fibrosis associated with experimental Fasciola hepatica infection: roles of Fas2 proteinase and hepatic stellate cell activation. The Journal of parasitology\| PubMed ID: 21348611	2011
Focus. Journal of hepatology\| PubMed ID: 21396971	2011
Mechanisms of hepatic fibrogenesis. Best practice & research. Clinical gastroenterology\| PubMed ID: 21497738	2011
Scraping fibrosis: expressway to the core of fibrosis. Nature medicine\| PubMed ID: 21546973	2011
Carcinogen-induced hepatic tumors in KLF6+/- mice recapitulate aggressive human hepatocellular carcinoma associated with p53 pathway deregulation. Hepatology (Baltimore, Md.)\| PubMed ID: 21563203	2011
[Polymorphism of ornithine decarboxylase antizyme inhibitor 1 gene is associated with liver cirrhosis in Chinese hepatitis B patients]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology\| PubMed ID: 21586232	2011
Focus. Journal of hepatology\| PubMed ID: 21621571	2011
Gene-expression signature of vascular invasion in hepatocellular carcinoma. Journal of hepatology\| PubMed ID: 21703203	2011
Nature, natural and NAFLD. Journal of hepatology\| PubMed ID: 21767508	2011
A polymorphism that delays fibrosis in hepatitis C promotes alternative splicing of AZIN1, reducing fibrogenesis. Hepatology (Baltimore, Md.)\| PubMed ID: 21837750	2011
Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression. Hepatology (Baltimore, Md.)\| PubMed ID: 21898476	2012
Focus. Journal of hepatology\| PubMed ID: 21906568	2012
Human hepatic stellate cell line (LX-2) exhibits characteristics of bone marrow-derived mesenchymal stem cells. Experimental and molecular pathology\| PubMed ID: 21930125	2011
Loss of discoidin domain receptor 2 promotes hepatic fibrosis after chronic carbon tetrachloride through altered paracrine interactions between hepatic stellate cells and liver-associated ma... The American journal of pathology\| PubMed ID: 22019896	2011
Current status of novel antifibrotic therapies in patients with chronic liver disease. Therapeutic advances in gastroenterology\| PubMed ID: 22043231	2011
Discoidin domain receptor 2 deficiency predisposes hepatic tissue to colon carcinoma metastasis. Gut\| PubMed ID: 22071959	2012
Focus. An emerging conceptual scaffold for NASH. Journal of hepatology\| PubMed ID: 22075260	2012
Glucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease. Hepatology (Baltimore, Md.)\| PubMed ID: 22095588	2012
Genomics and proteomics in liver fibrosis and cirrhosis. Fibrogenesis & tissue repair\| PubMed ID: 22214245	2012
Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues. Gastroenterology\| PubMed ID: 22240484	2012
A silent partner no longer – sinusoidal endothelial cells in liver homeostasis and disease. Journal of hepatology\| PubMed ID: 22322233	2012
Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib. Journal of hepatology\| PubMed ID: 22322234	2012
Fibrosis-dependent mechanisms of hepatocarcinogenesis. Hepatology (Baltimore, Md.)\| PubMed ID: 22378017	2012
Anti-fibrotic activity and enhanced interleukin-6 production by hepatic stellate cells in response to imatinib mesylate. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 22507133	2012
Focus. Metchnikoff, macrophages and the metabolic syndrome. Journal of hepatology\| PubMed ID: 22522383	2012
Enhanced hepatocarcinogenesis in mouse models and human hepatocellular carcinoma by coordinate KLF6 depletion and increased messenger RNA splicing. Hepatology (Baltimore, Md.)\| PubMed ID: 22535637	2012
CD11b(+) Gr1(+) bone marrow cells ameliorate liver fibrosis by producing interleukin-10 in mice. Hepatology (Baltimore, Md.)\| PubMed ID: 22544759	2012
Autophagy fuels tissue fibrogenesis. Autophagy\| PubMed ID: 22617442	2012
Focus. Journal of hepatology\| PubMed ID: 22691572	2012
The role of chemokines in acute liver injury. Frontiers in physiology\| PubMed ID: 22723782	2012
Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 22811581	2012
High mobility group box 1 activates Toll like receptor 4 signaling in hepatic stellate cells. Life sciences\| PubMed ID: 22841886	2012
Hepatocyte growth factor enhances alternative splicing of the Kruppel-like factor 6 (KLF6) tumor suppressor to promote growth through SRSF1. Molecular cancer research : MCR\| PubMed ID: 22859706	2012
Antifibrotic activity of sorafenib in experimental hepatic fibrosis: refinement of inhibitory targets, dosing, and window of efficacy in vivo. Digestive diseases and sciences\| PubMed ID: 22918681	2013
Focus. Journal of hepatology\| PubMed ID: 22922569	2012
Protect thee from the sins of thy fathers? Nature medicine\| PubMed ID: 22961157	2012
A novel murine model to deplete hepatic stellate cells uncovers their role in amplifying liver damage in mice. Hepatology (Baltimore, Md.)\| PubMed ID: 22961591	2013
Reduced hepatic stellate cell expression of Kruppel-like factor 6 tumor suppressor isoforms amplifies fibrosis during acute and chronic rodent liver injury. Hepatology (Baltimore, Md.)\| PubMed ID: 22961688	2013
Vascular injury triggers Krüppel-like factor 6 mobilization and cooperation with specificity protein 1 to promote endothelial activation through upregulation of the activin receptor-like kin... Circulation research\| PubMed ID: 23048070	2013
Focus. Journal of hepatology\| PubMed ID: 23085646	2013
The expression patterns and clinical significance of microRNAs in liver diseases and hepatocellular carcinoma. Current pharmaceutical design\| PubMed ID: 23092345	2013
Autophagy and mesenchymal cell fibrogenesis. Biochimica et biophysica acta\| PubMed ID: 23142802	2012
Focus. Journal of hepatology\| PubMed ID: 23247068	2013
Cellular basis of hepatic fibrosis and its role in inflammation and cancer. Frontiers in bioscience (Scholar edition)\| PubMed ID: 23277047	2013
A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor-β and vascular endothelial growth factor signalling. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 23279742	2013
Liver fibrosis in 2012: Convergent pathways that cause hepatic fibrosis in NASH. Nature reviews. Gastroenterology & hepatology\| PubMed ID: 23296246	2013
Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis. Hepatology (Baltimore, Md.)\| PubMed ID: 23299969	2013
Therapy for fibrotic diseases: nearing the starting line. Science translational medicine\| PubMed ID: 23303606	2013
Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma. Gastroenterology\| PubMed ID: 23313965	2013
Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis. Gastroenterology\| PubMed ID: 23333348	2013
Hepatitis Outreach Network: a practical strategy for hepatitis screening with linkage to care in foreign-born communities. Journal of hepatology\| PubMed ID: 23333446	2013
Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis. Journal of hepatology\| PubMed ID: 23353867	2013
Focus. Journal of hepatology\| PubMed ID: 23376365	2013
Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy. Journal of hepatology\| PubMed ID: 23485523	2013
Preface to BBA issue devoted to fibrosis. Biochimica et biophysica acta\| PubMed ID: 23507143	2013
Focus. Journal of hepatology\| PubMed ID: 23583274	2013
Focus. Journal of hepatology\| PubMed ID: 23770255	2013
Functions of autophagy in normal and diseased liver. Autophagy\| PubMed ID: 23774882	2013
CXCL12 induces hepatic stellate cell contraction through a calcium-independent pathway. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 23812037	2013
Genome-wide Transcriptome Analysis Identifies Novel Gene Signatures Implicated in Human Chronic Liver Disease. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 23812039	2013
A candidate gene study for the association of host single nucleotide polymorphisms with liver cirrhosis risk in chinese hepatitis B patients. Genetic testing and molecular biomarkers\| PubMed ID: 23844940	2013
Focus. Journal of hepatology\| PubMed ID: 23958934	2013
β-Catenin signaling in hepatocellular cancer: Implications in inflammation, fibrosis, and proliferation. Cancer letters\| PubMed ID: 24071572	2014
Genetic characteristics of the human hepatic stellate cell line LX-2. PloS one\| PubMed ID: 24116068	2013
Focus. Journal of hepatology\| PubMed ID: 24121095	2014
Regression of fibrosis and reversal of cirrhosis in rats by galectin inhibitors in thioacetamide-induced liver disease. PloS one\| PubMed ID: 24130706	2013
Hepatic stellate cells and liver fibrosis. Comprehensive Physiology\| PubMed ID: 24265236	2013
Contributions of metabolic dysregulation and inflammation to nonalcoholic steatohepatitis, hepatic fibrosis, and cancer. Current opinion in oncology\| PubMed ID: 24275855	2014
"There are decades where nothing happens; and there are weeks where decades happen"--Vladimir Ilyich Lenin. Journal of hepatology\| PubMed ID: 24333649	2014
Replacing a crystal ball with a calculator in predicting liver disease outcomes. Journal of hepatology\| PubMed ID: 24486331	2014
Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24591364	2014
Transporting pharmacogenomics into clinical practice. Journal of hepatology\| PubMed ID: 24703955	2014
Reversal, maintenance or progression: what happens to the liver after a virologic cure of hepatitis C? Antiviral research\| PubMed ID: 24726738	2014
Association of genetic variants with rapid fibrosis: progression after liver transplantation for hepatitis C. Transplantation\| PubMed ID: 24770613	2014
Hepatic fibrosis and the microenvironment: fertile soil for hepatocellular carcinoma development. Gene expression\| PubMed ID: 24801168	2014
NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity. Nature communications\| PubMed ID: 24849286	2014
LAP degradation product reflects plasma kallikrein-dependent TGF-β activation in patients with hepatic fibrosis. SpringerPlus\| PubMed ID: 24877031	2014
Tracking HCC pathogenesis but not the tumor cells after biopsy. Journal of hepatology\| PubMed ID: 24915611	2014
A genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deterioration. Gut\| PubMed ID: 25143343	2015
Final and future frontiers. Journal of hepatology\| PubMed ID: 25149111	2014
Inhibition of the CXCL12/CXCR4 chemokine axis with AMD3100, a CXCR4 small molecule inhibitor, worsens murine hepatic injury. Hepatology research : the official journal of the Japan Society of Hepatology\| PubMed ID: 25163538	2015
Focusing on the past, present, and future of hepatology. Journal of hepatology\| PubMed ID: 25195549	2014
IL-17A enhances the expression of profibrotic genes through upregulation of the TGF-β receptor on hepatic stellate cells in a JNK-dependent manner. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25210118	2014
The past 10 years of gastroenterology and hepatology-reflections and predictions. Nature reviews. Gastroenterology & hepatology\| PubMed ID: 25291429	2014
Alcohol and inflammatory responses: summary of the 2013 Alcohol and Immunology Research Interest Group (AIRIG) meeting. Alcohol (Fayetteville, N.Y.)\| PubMed ID: 25468277	2015
Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: findings and recommendations from an American Association for the Study of Liver Diseases-U.S... Hepatology (Baltimore, Md.)\| PubMed ID: 25557690	2015
Strategies and endpoints of antifibrotic drug trials: Summary and recommendations from the AASLD Emerging Trends Conference, Chicago, June 2014. Hepatology (Baltimore, Md.)\| PubMed ID: 25626988	2015
Principles on the path to a hepatologist's enlightenment. Hepatology (Baltimore, Md.)\| PubMed ID: 25645892	2015
β-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis. Journal of hepatology\| PubMed ID: 25678385	2015
Pathobiology of liver fibrosis: a translational success story. Gut\| PubMed ID: 25681399	2015
Epithelial Xbp1 is required for cellular proliferation and differentiation during mammary gland development. Molecular and cellular biology\| PubMed ID: 25713103	2015
Preserved Expression of mRNA Coding von Willebrand Factor-Cleaving Protease ADAMTS13 by Selenite and Activated Protein C. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 25860876	2015
Weight Loss Through Lifestyle Modification Significantly Reduces Features of Nonalcoholic Steatohepatitis. Gastroenterology\| PubMed ID: 25865049	2015
Hepatic fibrosis: Concept to treatment. Journal of hepatology\| PubMed ID: 25920084	2015
Granulocyte macrophage colony-stimulating factor is required for aortic dissection/intramural haematoma. Nature communications\| PubMed ID: 25923510	2015
Emerging and disease-specific mechanisms of hepatic stellate cell activation. Seminars in liver disease\| PubMed ID: 25974897	2015
Modulation of cardiac fibrosis by Krüppel-like factor 6 through transcriptional control of thrombospondin 4 in cardiomyocytes. Cardiovascular research\| PubMed ID: 25987545	2015
A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection. Gut\| PubMed ID: 26045137	2015
Hepatic Fibrosis: Emerging Therapies. Digestive diseases (Basel, Switzerland)\| PubMed ID: 26159266	2015
Induction and contribution of beta platelet-derived growth factor signalling by hepatic stellate cells to liver regeneration after partial hepatectomy in mice. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 26256287	2015
L(59) TGF-β LAP degradation products serve as a promising blood biomarker for liver fibrogenesis in mice. Fibrogenesis & tissue repair\| PubMed ID: 26379781	2015