Vivien R. Sutton

Cancer Immunology Program, Peter MacCallum Cancer Centre

Affiliated withPeter MacCallum Cancer Centre

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2014

Other Publications

Article	Year
A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death. The Journal of cell biology\| PubMed ID: 12538642	2003
Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors. Immunity\| PubMed ID: 12648450	2003
Purification of natural killer cell cytotoxic granules for assaying target cell apoptosis. Journal of immunological methods\| PubMed ID: 12738359	2003
Granzyme B: pro-apoptotic, antiviral and antitumor functions. Current opinion in immunology\| PubMed ID: 14499262	2003
A central role for Bid in granzyme B-induced apoptosis. The Journal of biological chemistry\| PubMed ID: 15574417	2005
A critical role for granzyme B, in addition to perforin and TNFalpha, in alloreactive CTL-induced mouse pancreatic beta cell death. Transplantation\| PubMed ID: 16436955	2006
Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis. The Journal of cell biology\| PubMed ID: 16606695	2006
Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid. Diabetes\| PubMed ID: 16873683	2006
Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis. The Journal of cell biology\| PubMed ID: 17283185	2007
Perforin activity and immune homeostasis: the common A91V polymorphism in perforin results in both presynaptic and postsynaptic defects in function. Blood\| PubMed ID: 17475905	2007
Measuring cell death mediated by cytotoxic lymphocytes or their granule effector molecules. Methods (San Diego, Calif.)\| PubMed ID: 18314055	2008
Dihydrofuro[3,4-c]pyridinones as inhibitors of the cytolytic effects of the pore-forming glycoprotein perforin. Journal of medicinal chemistry\| PubMed ID: 19007200	2008
Cathepsin H is an additional convertase of pro-granzyme B. The Journal of biological chemistry\| PubMed ID: 20435891	2010
Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L. Immunology\| PubMed ID: 20497254	2010
Proteases in lymphocyte killer function: redundancy, polymorphism and questions remaining. Biological chemistry\| PubMed ID: 20731542	2010
Cathepsin C limits acute viral infection independently of NK cell and CD8+ T-cell cytolytic function. Immunology and cell biology\| PubMed ID: 20975734	2011
A critical role for granzymes in antigen cross-presentation through regulating phagocytosis of killed tumor cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21709155	2011
Activated mouse B cells lack expression of granzyme B. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22427643	2012
A novel role for granzymes in anti-tumor immunity. Oncoimmunology\| PubMed ID: 22720248	2012
Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack. Blood\| PubMed ID: 23377437	2013
Granzyme h is a novel protease expressed by human mast cells. International archives of allergy and immunology\| PubMed ID: 25342632	2014