Shane R. Thomas

Centre for Vascular Research, University of New South Wales

Affiliated withUniversity of New South Wales

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2015

Other Publications

Article	Year
Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway. The Journal of biological chemistry\| PubMed ID: 11744698	2002
Vitamin E oxidation in human atherosclerotic lesions. Circulation research\| PubMed ID: 11861423	2002
The heme environment of recombinant human indoleamine 2,3-dioxygenase. Structural properties and substrate-ligand interactions. The Journal of biological chemistry\| PubMed ID: 11867636	2002
Regulation of angiogenesis by glycogen synthase kinase-3beta. The Journal of biological chemistry\| PubMed ID: 12167628	2002
Measurements of redox control of nitric oxide bioavailability. Methods in enzymology\| PubMed ID: 12481573	2002
Oxidative stress and endothelial nitric oxide bioactivity. Antioxidants & redox signaling\| PubMed ID: 12716478	2003
Beyond LDL oxidation: ROS in vascular signal transduction. Free radical biology & medicine\| PubMed ID: 12853068	2003
L-Homocysteine and L-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells. Free radical biology & medicine\| PubMed ID: 14980706	2004
Determination of the nature of the heme environment in nitrosyl indoleamine 2,3-dioxygenase using Multiple-scattering analyses of X-ray absorption fine structure. Biochemistry\| PubMed ID: 15109246	2004
Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling. The Journal of biological chemistry\| PubMed ID: 15180991	2004
Hypochlorous acid impairs endothelium-derived nitric oxide bioactivity through a superoxide-dependent mechanism. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 15331437	2004
Activation of endothelial nitric-oxide synthase by the p38 MAPK in response to black tea polyphenols. The Journal of biological chemistry\| PubMed ID: 15333638	2004
Processes involved in the site-specific effect of probucol on atherosclerosis in apolipoprotein E gene knockout mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 15961704	2005
Hydrogen peroxide restrains endothelium-derived nitric oxide bioactivity -- role for iron-dependent oxidative stress. Free radical biology & medicine\| PubMed ID: 16864001	2006
Molecules in focus: indoleamine 2,3-dioxygenase. The international journal of biochemistry & cell biology\| PubMed ID: 17320464	2007
Post-translational regulation of human indoleamine 2,3-dioxygenase activity by nitric oxide. The Journal of biological chemistry\| PubMed ID: 17535808	2007
Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells. The Journal of biological chemistry\| PubMed ID: 18299324	2008
Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities. Antioxidants & redox signaling\| PubMed ID: 18707220	2008
Suppression of the JNK pathway by induction of a metabolic stress response prevents vascular injury and dysfunction. Circulation\| PubMed ID: 18809807	2008
The selenazal drug ebselen potently inhibits indoleamine 2,3-dioxygenase by targeting enzyme cysteine residues. Biochemistry\| PubMed ID: 20000778	2010
Kynurenine is an endothelium-derived relaxing factor produced during inflammation. Nature medicine\| PubMed ID: 20190767	2010
Urate as a physiological substrate for myeloperoxidase: implications for hyperuricemia and inflammation. The Journal of biological chemistry\| PubMed ID: 21266577	2011
Flavivirus infection induces indoleamine 2,3-dioxygenase in human monocyte-derived macrophages via tumor necrosis factor and NF-ÎºB. Journal of leukocyte biology\| PubMed ID: 22301793	2012
Sustained expression of heme oxygenase-1 alters iron homeostasis in nonerythroid cells. Free radical biology & medicine\| PubMed ID: 22579918	2012
Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells. Free radical biology & medicine\| PubMed ID: 23059132	2012
Human indoleamine 2,3-dioxygenase is a catalyst of physiological heme peroxidase reactions: implications for the inhibition of dioxygenase activity by hydrogen peroxide. The Journal of biological chemistry\| PubMed ID: 23209301	2013
Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter... Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 23989929	2013
Indoleamine-2,3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans. Free radical biology & medicine\| PubMed ID: 24145120	2014
Mechanism and regulation of peroxidase-catalyzed nitric oxide consumption in physiological fluids: critical protective actions of ascorbate and thiocyanate. Free radical biology & medicine\| PubMed ID: 24704973	2014
The freestyle aortic bioprosthesis: a systematic review. Heart, lung & circulation\| PubMed ID: 25047283	2014
Apolipoprotein A-I increases insulin secretion and production from pancreatic β-cells via a G-protein-cAMP-PKA-FoxO1-dependent mechanism. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 25147338	2014
Phenazine virulence factor binding to extracellular DNA is important for Pseudomonas aeruginosa biofilm formation. Scientific reports\| PubMed ID: 25669133	2015