Canhui Li

Programme in Molecular Structure and Function, Hospital for Sick Children

Affiliated withHospital for Sick Children

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2015

Other Publications

Article	Year
Studies of the molecular basis for cystic fibrosis using purified reconstituted CFTR protein. Methods in molecular medicine\| PubMed ID: 11917519	2002
CFTR directly mediates nucleotide-regulated glutathione flux. The EMBO journal\| PubMed ID: 12727866	2003
Stable dimeric assembly of the second membrane-spanning domain of CFTR (cystic fibrosis transmembrane conductance regulator) reconstitutes a chloride-selective pore. The Biochemical journal\| PubMed ID: 12892562	2003
Phosphorylation-induced conformational changes of cystic fibrosis transmembrane conductance regulator monitored by attenuated total reflection-Fourier transform IR spectroscopy and fluoresce... The Journal of biological chemistry\| PubMed ID: 14660584	2004
Methods to study CFTR protein in vitro. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society\| PubMed ID: 15463933	2004
The patch-clamp and planar lipid bilayer techniques: powerful and versatile tools to investigate the CFTR Cl- channel. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society\| PubMed ID: 15463939	2004
Determination of CFTR chloride channel activity and pharmacology using radiotracer flux methods. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society\| PubMed ID: 15463942	2004
Evaluation of the membrane-spanning domain of ClC-2. The Biochemical journal\| PubMed ID: 16526942	2006
Nucleotides bind to the C-terminus of ClC-5. The Biochemical journal\| PubMed ID: 16686597	2006
The intact CFTR protein mediates ATPase rather than adenylate kinase activity. The Biochemical journal\| PubMed ID: 18241200	2008
Probing structure-function relationships and gating mechanisms in the CorA Mg2+ transport system. The Journal of biological chemistry\| PubMed ID: 18276588	2008
Evidence for a superoxide permeability pathway in endosomal membranes. Molecular and cellular biology\| PubMed ID: 18378695	2008
Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease. The Biochemical journal\| PubMed ID: 18945216	2009
A small-molecule modulator interacts directly with deltaPhe508-CFTR to modify its ATPase activity and conformational stability. Molecular pharmacology\| PubMed ID: 19339490	2009
Structural basis for alginate secretion across the bacterial outer membrane. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21778407	2011
Synthesis and properties of molecular probes for the rescue site on mutant cystic fibrosis transmembrane conductance regulator. Journal of medicinal chemistry\| PubMed ID: 22074181	2011
Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent m... The Journal of biological chemistry\| PubMed ID: 22942289	2012
VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface. Chemistry & biology\| PubMed ID: 24726831	2014