Philip Norris

Blood Systems Research Institute

Affiliated withBlood Systems Research Institute University of California, San Francisco

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 31	2015

Other Publications

Article	Year
Agreement among HLA antibody detection assays is higher in ever-pregnant donors and improved using a consensus cutoff. Transfusion\| PubMed ID: 21087285	2011
CD4(+) T helper cells and the role they play in viral control. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 12110945	2002
Labeling antigen-specific CD4(+) T cells with class II MHC oligomers. Journal of immunological methods\| PubMed ID: 12213343	2002
Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides. Journal of virology\| PubMed ID: 15078927	2004
Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells. AIDS research and human retroviruses\| PubMed ID: 15117455	2004
Heat shock protein-mediated cross-presentation of exogenous HIV antigen on HLA class I and class II. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15265933	2004
Beyond help: direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells. Journal of virology\| PubMed ID: 15280492	2004
A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15331779	2004
Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope. Molecular immunology\| PubMed ID: 16216327	2006
The effects of early antiretroviral therapy and its discontinuation on the HIV-specific antibody response. AIDS research and human retroviruses\| PubMed ID: 16831088	2006
The antigenic determinants on HIV p24 for CD4+ T cell inhibiting antibodies as determined by limited proteolysis, chemical modification, and mass spectrometry. Journal of the American Society for Mass Spectrometry\| PubMed ID: 16875837	2006
Elevations in IL-10, TNF-alpha, and IFN-gamma from the earliest point of HIV Type 1 infection. AIDS research and human retroviruses\| PubMed ID: 16910831	2006
Transfusion-associated microchimerism: a new complication of blood transfusions in severely injured patients. Seminars in hematology\| PubMed ID: 17198844	2007
Influenza viremia and the potential for blood-borne transmission. Transfusion\| PubMed ID: 17524100	2007
Nanoparticle-Based biobarcode amplification assay (BCA) for sensitive and early detection of human immunodeficiency type 1 capsid (p24) antigen. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 17693896	2007
Loss of T cell responses following long-term cryopreservation. Journal of immunological methods\| PubMed ID: 17707394	2007
Comprehensive analysis of west nile virus-specific T cell responses in humans. The Journal of infectious diseases\| PubMed ID: 18422442	2008
Suppression of HIV-1 plasma viral load below detection preserves IL-17 producing T cells in HIV-1 infection. AIDS (London, England)\| PubMed ID: 18453860	2008
Interferon and interferon-induced chemokine expression is associated with control of acute viremia in West Nile virus-infected blood donors. The Journal of infectious diseases\| PubMed ID: 18729779	2008
Virus and antibody dynamics in acute west nile virus infection. The Journal of infectious diseases\| PubMed ID: 18729783	2008
Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18802085	2008
Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy. Journal of virology\| PubMed ID: 18945778	2009
Long-term in vitro reactivity for human leukocyte antigen antibodies and comparison of detection using serum versus plasma. Transfusion\| PubMed ID: 18980615	2009
Induction of a striking systemic cytokine cascade prior to peak viremia in acute human immunodeficiency virus type 1 infection, in contrast to more modest and delayed responses in acute hepa... Journal of virology\| PubMed ID: 19176632	2009
The effect of previous pregnancy and transfusion on HLA alloimmunization in blood donors: implications for a transfusion-related acute lung injury risk reduction strategy. Transfusion\| PubMed ID: 19453983	2009
Understanding loss of donor white blood cell immunogenicity after pathogen reduction: mechanisms of action in ultraviolet illumination and riboflavin treatment. Transfusion\| PubMed ID: 19682337	2009
Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain. Immunity\| PubMed ID: 19833088	2009
The importance of Foxp3 antibody and fixation/permeabilization buffer combinations in identifying CD4+CD25+Foxp3+ regulatory T cells. Cytometry. Part A : the journal of the International Society for Analytical Cytology\| PubMed ID: 19845018	2009
Tregs control the development of symptomatic West Nile virus infection in humans and mice. The Journal of clinical investigation\| PubMed ID: 19855131	2009
A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties. European journal of immunology\| PubMed ID: 19877008	2010
HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection. Journal of clinical microbiology\| PubMed ID: 19906903	2010
Prevalence of HLA antibodies in remotely transfused or alloexposed volunteer blood donors. Transfusion\| PubMed ID: 20070615	2010
Identification of specificities of antibodies against human leukocyte antigens in blood donors. Transfusion\| PubMed ID: 20158682	2010
HIV+ elite controllers have low HIV-specific T-cell activation yet maintain strong, polyfunctional T-cell responses. AIDS (London, England)\| PubMed ID: 20400885	2010
Elevated caspase-3 expression and T-cell activation in elite suppressors. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 20418727	2010
Human T cell leukemia virus type 1 infection drives spontaneous proliferation of natural killer cells. Virulence\| PubMed ID: 20640055	2010
Evidence of persistent low-level viremia in long-term HAART-suppressed, HIV-infected individuals. AIDS (London, England)\| PubMed ID: 20651585	2010
Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. Journal of virology\| PubMed ID: 20686016	2010
CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset. Blood\| PubMed ID: 20733159	2010
The frequency and specificity of human neutrophil antigen antibodies in a blood donor population. Transfusion\| PubMed ID: 20977484	2011
Effects of blood sample age at time of separation on measured cytokine concentrations in human plasma. Clinical and vaccine immunology : CVI\| PubMed ID: 21159926	2011
A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers. PloS one\| PubMed ID: 21305005	2011
Establishing assay cutoffs for HLA antibody screening of apheresis donors. Transfusion\| PubMed ID: 21332726	2011
Properties of stored red blood cells: understanding immune and vascular reactivity. Transfusion\| PubMed ID: 21496052	2011
[West Nile virus - I. conquest of the West]. Médecine sciences : M/S\| PubMed ID: 21524401	2011
[West Nile virus. II. Immunopathophysiology in humans]. Médecine sciences : M/S\| PubMed ID: 21524402	2011
Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. Science translational medicine\| PubMed ID: 21543722	2011
The effect of HIV infection and HAART on inflammatory biomarkers in a population-based cohort of women. AIDS (London, England)\| PubMed ID: 21572306	2011
Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy. PloS one\| PubMed ID: 21573003	2011
Multisite comparison of high-sensitivity multiplex cytokine assays. Clinical and vaccine immunology : CVI\| PubMed ID: 21697338	2011
Identifying the early post-HIV antibody seroconversion period. The Journal of infectious diseases\| PubMed ID: 21791654	2011
Association between HLA class I and class II alleles and the outcome of West Nile virus infection: an exploratory study. PloS one\| PubMed ID: 21829673	2011
Transfusion-related acute lung injury: incidence and risk factors. Blood\| PubMed ID: 22117051	2012
Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity. Blood\| PubMed ID: 22134167	2012
Sensitive detection assays for influenza RNA do not reveal viremia in US blood donors. The Journal of infectious diseases\| PubMed ID: 22293429	2012
Distinct roles of trauma and transfusion in induction of immune modulation after injury. Transfusion\| PubMed ID: 22452342	2012
Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection. The Journal of general virology\| PubMed ID: 22535775	2012
Potential cardiovascular disease risk markers among HIV-infected women initiating antiretroviral treatment. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 22592585	2012
Soluble mediators of inflammation in HIV and their implications for therapeutics and vaccine development. Cytokine & growth factor reviews\| PubMed ID: 22743035	2012
Lower-sensitivity and avidity modifications of the vitros anti-HIV 1+2 assay for detection of recent HIV infections and incidence estimation. Journal of clinical microbiology\| PubMed ID: 23035182	2012
Association of subclinical atherosclerosis with lipid levels amongst antiretroviral-treated and untreated HIV-infected women in the Women's Interagency HIV study. Atherosclerosis\| PubMed ID: 23089369	2012
IL-1β signaling promotes CNS-intrinsic immune control of West Nile virus infection. PLoS pathogens\| PubMed ID: 23209411	2012
Lot-to-lot variability in HLA antibody screening using a multiplexed bead-based assay. Transfusion\| PubMed ID: 23305156	2013
Low-level HLA antibodies do not predict platelet transfusion failure in TRAP study participants. Blood\| PubMed ID: 23393051	2013
Treatment-related changes in serum lipids and inflammation: clinical relevance remains unclear. Analyses from the Women's Interagency HIV study. AIDS (London, England)\| PubMed ID: 23435295	2013
Immune modulation and lack of alloimmunization following transfusion with pathogen-reduced platelets in mice. Transfusion\| PubMed ID: 23451715	2013
CD57 expression and cytokine production by T cells in lesional and unaffected skin from patients with psoriasis. PloS one\| PubMed ID: 23468834	2013
Fetal production of growth factors and inflammatory mediators predicts pulmonary hypertension in congenital diaphragmatic hernia. Pediatric research\| PubMed ID: 23770923	2013
Leukoreduction and ultraviolet treatment reduce both the magnitude and the duration of the HLA antibody response. Transfusion\| PubMed ID: 23808544	2014
In vitro measures of membrane changes reveal differences between red blood cells stored in saline-adenine-glucose-mannitol and AS-1 additive solutions: a paired study. Transfusion\| PubMed ID: 23869602	2014
Plasma monocyte chemoattractant protein-1 and tumor necrosis factor-α levels predict the presence of coronary artery calcium in HIV-infected individuals independent of traditional cardiovasc... AIDS research and human retroviruses\| PubMed ID: 23984974	2014
IL-1Β enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular dis... PloS one\| PubMed ID: 24086545	2013
Cytokine and chemokine responses in the acute phase of hepatitis B virus replication in naive and previously vaccinated blood and plasma donors. The Journal of infectious diseases\| PubMed ID: 24158960	2014
HIV RNA levels in plasma and cervical-vaginal lavage fluid in elite controllers and HAART recipients. AIDS (London, England)\| PubMed ID: 24326356	2014
Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro. Blood\| PubMed ID: 24335232	2014
Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adul... Atherosclerosis\| PubMed ID: 24401216	2014
Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV. PloS one\| PubMed ID: 24587328	2014
Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection. PloS one\| PubMed ID: 24642562	2014
Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*. Critical care medicine\| PubMed ID: 24776608	2014
Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers. AIDS research and human retroviruses\| PubMed ID: 24786365	2014
West Nile virus nucleic acid persistence in whole blood months after clearance in plasma: implication for transfusion and transplantation safety. Transfusion\| PubMed ID: 24965017	2014
A CD4+ T cell antagonist epitope down-regulates activating signaling proteins, up-regulates inhibitory signaling proteins and abrogates HIV-specific T cell function. Retrovirology\| PubMed ID: 24996903	2014
Albuminuria is associated with elevated acute phase reactants and proinflammatory markers in HIV-infected patients receiving suppressive combination antiretroviral therapy. AIDS research and human retroviruses\| PubMed ID: 25205472	2014
Role of microRNA modulation in the interferon-α/ribavirin suppression of HIV-1 in vivo. PloS one\| PubMed ID: 25275557	2014
Downregulation of Cytokines and Chemokines by GB Virus C After Transmission Via Blood Transfusion in HIV-Positive Blood Recipients. The Journal of infectious diseases\| PubMed ID: 25425697	2014
Recipient clinical risk factors predominate in possible transfusion-related acute lung injury. Transfusion\| PubMed ID: 25488517	2014
Soluble T Cell Immunoglobulin Mucin Domain 3 Is Shed from CD8+ T Cells by the Sheddase ADAM10, Is Increased in Plasma during Untreated HIV Infection, and Correlates with HIV Disease Progress... Journal of virology\| PubMed ID: 25609823	2015