Marc E. Rothenberg

Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine

Affiliated withCincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2015

Other Publications

Article	Year
The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity. Nature medicine\| PubMed ID: 23334847	2013
Anti-interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes. The Journal of allergy and clinical immunology\| PubMed ID: 14699394	2004
Eosinophilic gastrointestinal disorders (EGID). The Journal of allergy and clinical immunology\| PubMed ID: 14713902	2004
Transcript signatures in experimental asthma: identification of STAT6-dependent and -independent pathways. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14734765	2004
Foxa2 regulates alveolarization and goblet cell hyperplasia. Development (Cambridge, England)\| PubMed ID: 14757645	2004
Negative regulation of eosinophil recruitment to the lung by the chemokine monokine induced by IFN-gamma (Mig, CXCL9). Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14769916	2004
Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma. American journal of respiratory cell and molecular biology\| PubMed ID: 15087305	2004
Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 15224281	2004
T helper-2 immunity regulates bronchial hyperresponsiveness in eosinophil-associated gastrointestinal disease in mice. Gastroenterology\| PubMed ID: 15236177	2004
Eosinophilic esophagitis. The New England journal of medicine\| PubMed ID: 15329438	2004
VEGF obstructs the lungs. Nature medicine\| PubMed ID: 15459700	2004
Arginine in asthma and lung inflammation. The Journal of nutrition\| PubMed ID: 15465795	2004
Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15585884	2004
Eotaxin-1-regulated eosinophils have a critical role in innate immunity against experimental Brugia malayi infection. European journal of immunology\| PubMed ID: 15593125	2005
Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation. The Journal of biological chemistry\| PubMed ID: 15647285	2005
Expression and regulation of small proline-rich protein 2 in allergic inflammation. American journal of respiratory cell and molecular biology\| PubMed ID: 15731505	2005
Molecular mechanisms of anaphylaxis: lessons from studies with murine models. The Journal of allergy and clinical immunology\| PubMed ID: 15753886	2005
CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism. Blood\| PubMed ID: 15802529	2005
Analysis of the CCR3 promoter reveals a regulatory region in exon 1 that binds GATA-1. BMC immunology\| PubMed ID: 15807893	2005
Suppressive effect of IL-4 on IL-13-induced genes in mouse lung. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15814686	2005
Anti-IL-5 and hypereosinophilic syndromes. Clinical immunology (Orlando, Fla.)\| PubMed ID: 15870021	2005
Eliminating eosinophilic esophagitis. Clinical immunology (Orlando, Fla.)\| PubMed ID: 15885634	2005
Prevalence and outcome of allergic colitis in healthy infants with rectal bleeding: a prospective cohort study. Journal of pediatric gastroenterology and nutrition\| PubMed ID: 15990624	2005
Epicutaneous antigen exposure primes for experimental eosinophilic esophagitis in mice. Gastroenterology\| PubMed ID: 16143136	2005
The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16210640	2005
Transgenic expression of bean alpha-amylase inhibitor in peas results in altered structure and immunogenicity. Journal of agricultural and food chemistry\| PubMed ID: 16277398	2005
Eosinophilic esophagitis. Current opinion in pediatrics\| PubMed ID: 16282772	2005
The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease. Blood\| PubMed ID: 16418325	2006
Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. The Journal of clinical investigation\| PubMed ID: 16453027	2006
The arginine-arginase balance in asthma and lung inflammation. European journal of pharmacology\| PubMed ID: 16458291	2006
Eosinophil Function in Eosinophil-associated Gastrointestinal Disorders. Current allergy and asthma reports\| PubMed ID: 16476198	2006
IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts. The Journal of allergy and clinical immunology\| PubMed ID: 16522458	2006
The eosinophil. Annual review of immunology\| PubMed ID: 16551246	2006
Persistent effects induced by IL-13 in the lung. American journal of respiratory cell and molecular biology\| PubMed ID: 16645178	2006
Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16648267	2006
ICAM-1-dependent pathways regulate colonic eosinophilic inflammation. Journal of leukocyte biology\| PubMed ID: 16731772	2006
Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report. The Journal of allergy and clinical immunology\| PubMed ID: 16750989	2006
The role of Th2 cytokines, chemokines and parasite products in eosinophil recruitment to the gastrointestinal mucosa during helminth infection. European journal of immunology\| PubMed ID: 16783848	2006
CD48 is an allergen and IL-3-induced activation molecule on eosinophils. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16785501	2006
Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses. The Journal of allergy and clinical immunology\| PubMed ID: 16815139	2006
Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility. The Journal of allergy and clinical immunology\| PubMed ID: 16815164	2006
Experimental gastrointestinal allergy enhances pulmonary responses to specific and unrelated allergens. The Journal of allergy and clinical immunology\| PubMed ID: 16890767	2006
Quantity and distribution of eosinophils in the gastrointestinal tract of children. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society\| PubMed ID: 16944979	2006
Cationic amino acid transporter 2 regulates inflammatory homeostasis in the lung. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17003120	2006
Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17015747	2006
Potential of blood eosinophils, eosinophil-derived neurotoxin, and eotaxin-3 as biomarkers of eosinophilic esophagitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 17059896	2006
A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17060636	2006
Eosinophilic esophagitis: pathogenesis, genetics, and therapy. The Journal of allergy and clinical immunology\| PubMed ID: 17088129	2006
A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis. Gastroenterology\| PubMed ID: 17101314	2006
Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling. The American journal of pathology\| PubMed ID: 17148674	2006
Anti-IL-5 (mepolizumab) therapy for eosinophilic esophagitis. The Journal of allergy and clinical immunology\| PubMed ID: 17157662	2006
Allergen induced TFF2 is expressed by mucus-producing airway epithelial cells but is not a major regulator of inflammatory responses in the murine lung. Experimental lung research\| PubMed ID: 17169855	2006
Critical role for adaptive T cell immunity in experimental eosinophilic esophagitis in mice. Journal of leukocyte biology\| PubMed ID: 17194734	2007
Pediatric patients with eosinophilic esophagitis: an 8-year follow-up. The Journal of allergy and clinical immunology\| PubMed ID: 17258309	2007
CD48 is critically involved in allergic eosinophilic airway inflammation. American journal of respiratory and critical care medicine\| PubMed ID: 17290046	2007
Influence of cigarette smoke on the arginine pathway in asthmatic airways: increased expression of arginase I. The Journal of allergy and clinical immunology\| PubMed ID: 17291856	2007
Regulation of carcinogenesis by IL-5 and CCL11: a potential role for eosinophils in tumor immune surveillance. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17371978	2007
Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation. The Journal of clinical investigation\| PubMed ID: 17415415	2007
Eosinophils in the new millennium. The Journal of allergy and clinical immunology\| PubMed ID: 17451795	2007
Resistin-like molecule-beta is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 17545488	2007
Interplay of adaptive th2 immunity with eotaxin-3/c-C chemokine receptor 3 in eosinophilic esophagitis. Journal of pediatric gastroenterology and nutrition\| PubMed ID: 17592361	2007
Gastrointestinal eosinophilia. Immunology and allergy clinics of North America\| PubMed ID: 17868858	2007
Summary of the First International Gastrointestinal Eosinophil Research Symposium. Journal of pediatric gastroenterology and nutrition\| PubMed ID: 17873754	2007
An eosinophil hypothesis for functional dyspepsia. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 17916543	2007
Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. Gastroenterology\| PubMed ID: 17919504	2007
Basic pathogenesis of eosinophilic esophagitis. Gastrointestinal endoscopy clinics of North America\| PubMed ID: 18061107	2008
IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids. The Journal of allergy and clinical immunology\| PubMed ID: 18073124	2007
Esophageal remodeling develops as a consequence of tissue specific IL-5-induced eosinophilia. Gastroenterology\| PubMed ID: 18166354	2008
A dual activation and inhibition role for the paired immunoglobulin-like receptor B in eosinophils. Blood\| PubMed ID: 18316626	2008
Treatment of patients with the hypereosinophilic syndrome with mepolizumab. The New England journal of medicine\| PubMed ID: 18344568	2008
IL-4R alpha expression by bone marrow-derived cells is necessary and sufficient for host protection against acute schistosomiasis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18354220	2008
Surfactant protein D alters allergic lung responses in mice and human subjects. The Journal of allergy and clinical immunology\| PubMed ID: 18355911	2008
IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity. The Journal of experimental medicine\| PubMed ID: 18378796	2008
Eosinophils: biological properties and role in health and disease. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology\| PubMed ID: 18384431	2008
Anti-IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels. The Journal of allergy and clinical immunology\| PubMed ID: 18410960	2008
2007 E. Mead Johnson award: scientific pursuit of the allergy problem. Pediatric research\| PubMed ID: 18414146	2008
Clinical, pathologic, and molecular characterization of familial eosinophilic esophagitis compared with sporadic cases. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association\| PubMed ID: 18434257	2008
Origin, regulation and physiological function of intestinal oeosinophils. Best practice & research. Clinical gastroenterology\| PubMed ID: 18492563	2008
Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein. Journal of leukocyte biology\| PubMed ID: 18519743	2008
FIP1L1/PDGFRalpha synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome. Blood\| PubMed ID: 18539901	2008
Allergy and eosinophil-associated gastrointestinal disorders (EGID). Current opinion in immunology\| PubMed ID: 18721876	2008
Mitochondrial missile defense. Nature medicine\| PubMed ID: 18776879	2008
Intestinal macrophage/epithelial cell-derived CCL11/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18981162	2008
Targeting IL-4/IL-13 signaling to alleviate oral allergen-induced diarrhea. The Journal of allergy and clinical immunology\| PubMed ID: 18996576	2009
Resistin-like molecule alpha enhances myeloid cell activation and promotes colitis. The Journal of allergy and clinical immunology\| PubMed ID: 19084112	2008
Chemotactic factors associated with eosinophilic gastrointestinal diseases. Immunology and allergy clinics of North America\| PubMed ID: 19141349	2009
Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade. International immunology\| PubMed ID: 19147836	2009
Dissociation between symptoms and histological severity in pediatric eosinophilic esophagitis. Journal of pediatric gastroenterology and nutrition\| PubMed ID: 19179876	2009
Resistin-like molecule alpha decreases glucose tolerance during intestinal inflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19201890	2009
Biology of the eosinophil. Advances in immunology\| PubMed ID: 19231593	2009
Molecular diagnostics and treatment of patients with the hypereosinophilic syndrome. Clinical advances in hematology & oncology : H&O\| PubMed ID: 19274040	2009
MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19342679	2009
Eosinophilic esophagitis: concepts, controversies, and evidence. Current gastroenterology reports\| PubMed ID: 19463222	2009
Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mi... BMC immunology\| PubMed ID: 19486531	2009
Murine model of hypereosinophilic syndromes/chronic eosinophilic leukemia. International archives of allergy and immunology\| PubMed ID: 19494514	2009
CCR3 is a target for age-related macular degeneration diagnosis and therapy. Nature\| PubMed ID: 19525930	2009
Biology and treatment of eosinophilic esophagitis. Gastroenterology\| PubMed ID: 19596009	2009
Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner. Blood\| PubMed ID: 19641187	2009
Hypersensitivity and allergy: from mice to men. Current opinion in immunology\| PubMed ID: 19879743	2009
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. The Journal of allergy and clinical immunology\| PubMed ID: 19910029	2009
Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection. The Journal of experimental medicine\| PubMed ID: 19995957	2009
Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma. European journal of human genetics : EJHG\| PubMed ID: 20087405	2010
Persistent rotavirus vaccine shedding in a new case of severe combined immunodeficiency: A reason to screen. The Journal of allergy and clinical immunology\| PubMed ID: 20109754	2010
Health-related quality of life across pediatric chronic conditions. The Journal of pediatrics\| PubMed ID: 20117793	2010
Importance of cytokines in murine allergic airway disease and human asthma. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20130218	2010
Key advances in mechanisms of asthma, allergy, and immunology in 2009. The Journal of allergy and clinical immunology\| PubMed ID: 20159240	2010
Abnormal response to stress and impaired NPS-induced hyperlocomotion, anxiolytic effect and corticosterone increase in mice lacking NPSR1. Psychoneuroendocrinology\| PubMed ID: 20171785	2010
Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20208004	2010
Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nature genetics\| PubMed ID: 20208534	2010
Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51. The Journal of allergy and clinical immunology\| PubMed ID: 20371398	2010
Interleukin-15 expression is increased in human eosinophilic esophagitis and mediates pathogenesis in mice. Gastroenterology\| PubMed ID: 20381491	2010
Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract. The Journal of allergy and clinical immunology\| PubMed ID: 20392477	2010
Paired immunoglobulin-like receptor B (PIR-B) negatively regulates macrophage activation in experimental colitis. Gastroenterology\| PubMed ID: 20398663	2010
Indoor insect allergens are potent inducers of experimental eosinophilic esophagitis in mice. Journal of leukocyte biology\| PubMed ID: 20413729	2010
Hypereosinophilic syndromes and new therapeutic approaches including anti-IL-5. Expert review of clinical immunology\| PubMed ID: 20477604	2005
Arginase I suppresses IL-12/IL-23p40-driven intestinal inflammation during acute schistosomiasis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20483789	2010
IL-5 pathway inhibition in the treatment of asthma and Churg-Strauss syndrome. The Journal of allergy and clinical immunology\| PubMed ID: 20513522	2010
Involvement of mast cells in eosinophilic esophagitis. The Journal of allergy and clinical immunology\| PubMed ID: 20538331	2010
IL-13 induces esophageal remodeling and gene expression by an eosinophil-independent, IL-13R alpha 2-inhibited pathway. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20543112	2010
The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis. Respiratory research\| PubMed ID: 20576117	2010
Identification, epidemiology, and chronicity of pediatric esophageal eosinophilia, 1982-1999. The Journal of allergy and clinical immunology\| PubMed ID: 20620567	2010
Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. The Journal of allergy and clinical immunology\| PubMed ID: 20620568	2010
Refining the definition of hypereosinophilic syndrome. The Journal of allergy and clinical immunology\| PubMed ID: 20639008	2010
Innate sensing of nickel. Nature immunology\| PubMed ID: 20720584	2010
Acquired coenzyme Q10 deficiency in children with recurrent food intolerance and allergies. Mitochondrion\| PubMed ID: 20817046	2011
IL-13Rα2 has a protective role in a mouse model of cutaneous inflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20971924	2010
TGF-β1: Mediator of a feedback loop in eosinophilic esophagitis--or should we really say mastocytic esophagitis? The Journal of allergy and clinical immunology\| PubMed ID: 21134572	2010
The role of neuropeptide S and neuropeptide S receptor 1 in regulation of respiratory function in mice. Peptides\| PubMed ID: 21167892	2011
A striking local esophageal cytokine expression profile in eosinophilic esophagitis. The Journal of allergy and clinical immunology\| PubMed ID: 21211656	2011
Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion. The Journal of biological chemistry\| PubMed ID: 21303908	2011
Epigenetic regulation of the IL-13-induced human eotaxin-3 gene by CREB-binding protein-mediated histone 3 acetylation. The Journal of biological chemistry\| PubMed ID: 21325281	2011
Advances in mechanisms of asthma, allergy, and immunology in 2010. The Journal of allergy and clinical immunology\| PubMed ID: 21377038	2011
Differences in candidate gene association between European ancestry and African American asthmatic children. PloS one\| PubMed ID: 21387019	2011
Eosinophilic esophagitis: updated consensus recommendations for children and adults. The Journal of allergy and clinical immunology\| PubMed ID: 21477849	2011
Colonic eosinophilic inflammation in experimental colitis is mediated by Ly6C(high) CCR2(+) inflammatory monocyte/macrophage-derived CCL11. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21498668	2011
Psychological Functioning of Children and Adolescents With Eosinophil-Associated Gastrointestinal Disorders. Children's health care : journal of the Association for the Care of Children's Health\| PubMed ID: 21532963	2010
Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies. The Journal of allergy and clinical immunology\| PubMed ID: 21570716	2011
Agonist activation of f-actin-mediated eosinophil shape change and mediator release is dependent on Rac2. International archives of allergy and immunology\| PubMed ID: 21576984	2011
Long-term outcomes in pediatric-onset esophageal eosinophilia. The Journal of allergy and clinical immunology\| PubMed ID: 21636117	2011
MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21849676	2011
IL-13 receptor α1 differentially regulates aeroallergen-induced lung responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21957151	2011
Eosinophilic esophagitis: rapidly advancing insights. Annual review of medicine\| PubMed ID: 22034864	2012
Treatment adherence in pediatric eosinophilic gastrointestinal disorders. Journal of pediatric psychology\| PubMed ID: 22080457	2012
Development of a validated patient-reported symptom metric for pediatric eosinophilic esophagitis: qualitative methods. BMC gastroenterology\| PubMed ID: 22099448	2011
The pan-B cell marker CD22 is expressed on gastrointestinal eosinophils and negatively regulates tissue eosinophilia. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22190185	2012
Reslizumab in children and adolescents with eosinophilic esophagitis: results of a double-blind, randomized, placebo-controlled trial. The Journal of allergy and clinical immunology\| PubMed ID: 22206777	2012
Resistin-like molecule-α regulates IL-13-induced chemokine production but not allergen-induced airway responses. American journal of respiratory cell and molecular biology\| PubMed ID: 22246861	2012
Advances in mechanisms of asthma, allergy, and immunology in 2011. The Journal of allergy and clinical immunology\| PubMed ID: 22284930	2012
MicroRNA signature in patients with eosinophilic esophagitis, reversibility with glucocorticoids, and assessment as disease biomarkers. The Journal of allergy and clinical immunology\| PubMed ID: 22391115	2012
Behavioral functioning and treatment adherence in pediatric eosinophilic gastrointestinal disorders. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology\| PubMed ID: 22435992	2012
Comparative dietary therapy effectiveness in remission of pediatric eosinophilic esophagitis. The Journal of allergy and clinical immunology\| PubMed ID: 22541246	2012
The Greater Cincinnati Pediatric Clinic Repository: A Novel Framework for Childhood Asthma and Allergy Research. Pediatric allergy, immunology, and pulmonology\| PubMed ID: 22768387	2012
Behavioral feeding problems and parenting stress in eosinophilic gastrointestinal disorders in children. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology\| PubMed ID: 22882380	2012
Novel targeted therapies for eosinophilic disorders. The Journal of allergy and clinical immunology\| PubMed ID: 22935585	2012
Workshop report from the National Institutes of Health Taskforce on the Research Needs of Eosinophil-Associated Diseases (TREAD). The Journal of allergy and clinical immunology\| PubMed ID: 22935587	2012
Working with the US Food and Drug Administration: progress and timelines in understanding and treating patients with eosinophilic esophagitis. The Journal of allergy and clinical immunology\| PubMed ID: 22935588	2012
Development of the Pediatric Quality of Life Inventory™ Eosinophilic Esophagitis module items: qualitative methods. BMC gastroenterology\| PubMed ID: 23009120	2012
Long-term safety of mepolizumab for the treatment of hypereosinophilic syndromes. The Journal of allergy and clinical immunology\| PubMed ID: 23040887	2013
Reply: To PMID 22541246. The Journal of allergy and clinical immunology\| PubMed ID: 23127828	2013
Commentary on "Markers of Antigen Presentation And Activation On Eosinophils And T-Cells in the Esophageal Tissue of Patients With Eosinophilic Esophagitis" Journal of pediatric gastroenterology and nutrition\| PubMed ID: 23132165	2012
The Child Health Research Centers: twenty-one years of promoting the development of pediatrician scientists from 1990-2011. The Journal of pediatrics\| PubMed ID: 23171484	2012
ICON: Eosinophil Disorders. The World Allergy Organization journal\| PubMed ID: 23282419	2012
MiR-223 deficiency increases eosinophil progenitor proliferation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23325891	2013
Targeting eosinophils in allergy, inflammation and beyond. Nature reviews. Drug discovery\| PubMed ID: 23334207	2013
Advances in mechanisms of allergy and clinical immunology in 2012. The Journal of allergy and clinical immunology\| PubMed ID: 23352632	2013
PedsQL eosinophilic esophagitis module: feasibility, reliability, and validity. Journal of pediatric gastroenterology and nutrition\| PubMed ID: 23478422	2013
Targeted ablation of miR-21 decreases murine eosinophil progenitor cell growth. PloS one\| PubMed ID: 23533623	2013
Eosinophil adoptive transfer system to directly evaluate pulmonary eosinophil trafficking in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23536294	2013
Emerging concepts of dietary therapy for pediatric and adult eosinophilic esophagitis. Expert review of clinical immunology\| PubMed ID: 23557262	2013
High prevalence of eosinophilic esophagitis in patients with inherited connective tissue disorders. The Journal of allergy and clinical immunology\| PubMed ID: 23608731	2013
Current concepts on the pathogenesis of the hypereosinophilic syndrome/chronic eosinophilic leukemia. Translational oncogenomics\| PubMed ID: 23662039	2006
Expanding the paradigm of eosinophilic esophagitis: mast cells and IL-9. The Journal of allergy and clinical immunology\| PubMed ID: 23726533	2013
Diagnostic, functional, and therapeutic roles of microRNA in allergic diseases. The Journal of allergy and clinical immunology\| PubMed ID: 23735656	2013
Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations. Human genomics\| PubMed ID: 23829686	2013
Molecular diagnosis of eosinophilic esophagitis by gene expression profiling. Gastroenterology\| PubMed ID: 23978633	2013
IL-33 markedly activates murine eosinophils by an NF-κB-dependent mechanism differentially dependent upon an IL-4-driven autoinflammatory loop. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24043894	2013
Eosinophilic asthma: insights into the effects of reducing IL-5 receptor-positive cell levels. The Journal of allergy and clinical immunology\| PubMed ID: 24094543	2013
Paired immunoglobulin-like receptor A is an intrinsic, self-limiting suppressor of IL-5-induced eosinophil development. Nature immunology\| PubMed ID: 24212998	2014
Correlation of increased PARP14 and CCL26 expression in biopsies from children with eosinophilic esophagitis. The Journal of allergy and clinical immunology\| PubMed ID: 24238647	2014
Demethylation of the human eotaxin-3 gene promoter leads to the elevated expression of eotaxin-3. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24323578	2014
Increased prevalence of eosinophilic gastrointestinal disorders in pediatric PTEN hamartoma tumor syndromes. Journal of pediatric gastroenterology and nutrition\| PubMed ID: 24345843	2014
Mendelian inheritance of elevated serum tryptase associated with atopy and connective tissue abnormalities. The Journal of allergy and clinical immunology\| PubMed ID: 24472624	2014
The management of eosinophilic esophagitis. The journal of allergy and clinical immunology. In practice\| PubMed ID: 24565538	2013
Rab5 is a novel regulator of mast cell secretory granules: impact on size, cargo, and exocytosis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24696234	2014
Efficacy, dose reduction, and resistance to high-dose fluticasone in patients with eosinophilic esophagitis. Gastroenterology\| PubMed ID: 24768678	2014
Eosinophils and cancer. Cancer immunology research\| PubMed ID: 24778159	2014
Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease. Inflammatory bowel diseases\| PubMed ID: 24788216	2014
Carbonic anhydrase IV is expressed on IL-5-activated murine eosinophils. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24808371	2014
Genetic and epigenetic underpinnings of eosinophilic esophagitis. Gastroenterology clinics of North America\| PubMed ID: 24813515	2014
Murine models of eosinophilic leukemia: a model of FIP1L1-PDGFRα initiated chronic eosinophilic leukemia/systemic mastocytosis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24986627	2014
Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. Nature genetics\| PubMed ID: 25017104	2014
Roles and regulation of gastrointestinal eosinophils in immunity and disease. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25049430	2014
Intravenous anti-IL-13 mAb QAX576 for the treatment of eosinophilic esophagitis. The Journal of allergy and clinical immunology\| PubMed ID: 25226850	2014
IL-5 triggers a cooperative cytokine network that promotes eosinophil precursor maturation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25230753	2014
Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome. The Journal of allergy and clinical immunology\| PubMed ID: 25234644	2014
Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis. The Journal of allergy and clinical immunology\| PubMed ID: 25258143	2014
Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation. The Journal of allergy and clinical immunology\| PubMed ID: 25441638	2015
Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis. Frontiers in genetics\| PubMed ID: 25477900	2014
Making it big in allergy. The Journal of allergy and clinical immunology\| PubMed ID: 25567041	2015
Resistin-like Molecule Alpha in Allergen-induced Pulmonary Vascular Remodeling. American journal of respiratory cell and molecular biology\| PubMed ID: 25569618	2015