Irma Joosten

Laboratory of Medical Immunology, Radboud university medical centre

Affiliated withRadboud university medical centre

Research Area

Biography

Irma Joosten has not added Biography.
If you are Irma Joosten and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2016

Other Publications

Article	Year
Amniotic fluid soluble human leukocyte antigen G is markedly decreased in offspring with neural tube defects. Early human development\| PubMed ID: 11872314	2002
Altered phenotype of HLA-G expressing trophoblast and decidual natural killer cells in pathological pregnancies. Human reproduction (Oxford, England)\| PubMed ID: 11925408	2002
Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosi... Transplantation\| PubMed ID: 12792519	2003
The proportion of follicular fluid CD16+CD56DIM NK cells is increased in IVF patients with idiopathic infertility. Journal of reproductive immunology\| PubMed ID: 14568679	2003
IL-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory CD4+ T cells that require antigen-specific activation for suppression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14662842	2003
Shift in expression of HLA-G mRNA spliceforms in pregnancies complicated by preeclampsia. Journal of the Society for Gynecologic Investigation\| PubMed ID: 15120695	2004
A novel bispecific antihuman CD40/CD86 fusion protein with t-cell tolerizing potential. Transplantation\| PubMed ID: 15599306	2004
Tolerizing effects of co-stimulation blockade rest on functional dominance of CD4+CD25+ regulatory T cells. Transplantation\| PubMed ID: 15665762	2005
CD27/CFSE-based ex vivo selection of highly suppressive alloantigen-specific human regulatory T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15944257	2005
Cyclosporine preserves the anergic state of human T cells induced by costimulation blockade in vitro. Transplantation\| PubMed ID: 16123728	2005
Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells. Blood\| PubMed ID: 16210336	2006
Activation of NK cells by an endocytosed receptor for soluble HLA-G. PLoS biology\| PubMed ID: 16366734	2006
KIR and Human Leukocyte Antigen Genotype Associated Risk of Cytomegalovirus Disease in Renal Transplant Patients. Transplantation\| PubMed ID: 25427165	2015
CTLA-4 engagement and regulatory CD4+CD25+ T cells independently control CD8+-mediated responses under costimulation blockade. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16621989	2006
Ex vivo expansion of human CD4+ CD25high regulatory T cells from transplant recipients permits functional analysis of small blood samples. Journal of immunological methods\| PubMed ID: 16860335	2006
The immunosuppressive drug FK778 induces regulatory activity in stimulated human CD4+ CD25- T cells. Blood\| PubMed ID: 16902146	2007
Antigen-specific regulatory T-cell subsets in transplantation tolerance regulatory T-cell subset quality reduces the need for quantity. Human immunology\| PubMed ID: 17002896	2006
Allogeneic stimulation of naturally occurring CD4+CD25+ T cells induces strong regulatory capacity with increased donor-reactivity. Transplant immunology\| PubMed ID: 17493525	2007
KIR gene and KIR ligand analysis to predict graft rejection after renal transplantation. Transplantation\| PubMed ID: 17989611	2007
The presence of donor-specific human leukocyte antigen antibodies does not preclude successful withdrawal of tacrolimus in stable renal transplant recipients. Transplantation\| PubMed ID: 17998862	2007
A novel (Leu183Pro-)mutation in the HFE-gene co-inherited with the Cys282Tyr mutation in two unrelated Dutch hemochromatosis patients. Blood cells, molecules & diseases\| PubMed ID: 18042412	2008
Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy. PloS one\| PubMed ID: 18493605	2008
KIR2DS5 is associated with leukemia free survival after HLA identical stem cell transplantation in chronic myeloid leukemia patients. Molecular immunology\| PubMed ID: 18555529	2008
Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood\| PubMed ID: 18617638	2008
Immunological monitoring of renal transplant recipients to predict acute allograft rejection following the discontinuation of tacrolimus. PloS one\| PubMed ID: 18628993	2008
Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation. PloS one\| PubMed ID: 18776930	2008
Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis. Nature genetics\| PubMed ID: 19169253	2009
Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19318472	2009
The macrophage mannose receptor induces IL-17 in response to Candida albicans. Cell host & microbe\| PubMed ID: 19380112	2009
The inhibitory Fc gamma IIb receptor dampens TLR4-mediated immune responses and is selectively up-regulated on dendritic cells from rheumatoid arthritis patients with quiescent disease. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19734236	2009
High log-scale expansion of functional human natural killer cells from umbilical cord blood CD34-positive cells for adoptive cancer immunotherapy. PloS one\| PubMed ID: 20169160	2010
DNA-PKcs controls an endosomal signaling pathway for a proinflammatory response by natural killer cells. Science signaling\| PubMed ID: 20179272	2010
Liver grafts contain a unique subset of natural killer cells that are transferred into the recipient after liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 20583081	2010
Immunotherapy with regulatory T cells in transplantation. Immunotherapy\| PubMed ID: 20636028	2009
1,25-dihydroxyvitamin D3 modulates cytokine production induced by Candida albicans: impact of seasonal variation of immune responses. The Journal of infectious diseases\| PubMed ID: 21148505	2011
Anaphylaxis from passive transfer of peanut allergen in a blood product. The New England journal of medicine\| PubMed ID: 21591965	2011
Vitamin D(3) down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production. Cytokine\| PubMed ID: 21592820	2011
Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin. The Journal of investigative dermatology\| PubMed ID: 21654831	2011
Donor and recipient HLA/KIR genotypes do not predict liver transplantation outcome. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 21672051	2011
1,25-Dihydroxyvitamin D3 inhibits proliferation but not the suppressive function of regulatory T cells in the absence of antigen-presenting cells. Immunology\| PubMed ID: 22044285	2011
Koebner phenomenon in psoriasis is not associated with deletion of late cornified envelope genes LCE3B and LCE3C. The Journal of investigative dermatology\| PubMed ID: 22048733	2012
Seasonal variation in vitamin D₃ levels is paralleled by changes in the peripheral blood human T cell compartment. PloS one\| PubMed ID: 22235276	2012
Analyzing the homeostasis of signaling proteins by a combination of Western blot and fluorescence correlation spectroscopy. Biophysical journal\| PubMed ID: 22261070	2011
Translating the role of vitamin D3 in infectious diseases. Critical reviews in microbiology\| PubMed ID: 22304022	2012
Defining early human NK cell developmental stages in primary and secondary lymphoid tissues. PloS one\| PubMed ID: 22319595	2012
Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling. BMC immunology\| PubMed ID: 22413885	2012
Rho kinase inhibitor Y-27632 prolongs the life span of adult human keratinocytes, enhances skin equivalent development, and facilitates lentiviral transduction. Tissue engineering. Part A\| PubMed ID: 22519508	2012
Humoral anti-KLH responses in cancer patients treated with dendritic cell-based immunotherapy are dictated by different vaccination parameters. Cancer immunology, immunotherapy : CII\| PubMed ID: 22527252	2012
High-dose vitamin D3 supplementation is a requisite for modulation of skin-homing markers on regulatory T cells in HIV-infected patients. AIDS research and human retroviruses\| PubMed ID: 22720723	2013
Storage-induced changes in erythrocyte membrane proteins promote recognition by autoantibodies. PloS one\| PubMed ID: 22879923	2012
Humanized mouse model of skin inflammation is characterized by disturbed keratinocyte differentiation and influx of IL-17A producing T cells. PloS one\| PubMed ID: 23094018	2012
Co-culture of healthy human keratinocytes and T-cells promotes keratinocyte chemokine production and RORγt-positive IL-17 producing T-cell populations. Journal of dermatological science\| PubMed ID: 23127421	2013
CD19 is a useful B cell marker after treatment with rituximab: comment on the article by Jones et al. Arthritis and rheumatism\| PubMed ID: 23335076	2013
Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis. The Journal of clinical investigation\| PubMed ID: 23348739	2013
Iron status and systemic inflammation, but not gut inflammation, strongly predict gender-specific concentrations of serum hepcidin in infants in rural Kenya. PloS one\| PubMed ID: 23460869	2013
The effects of in vivo B-cell depleting therapy on ex-vivo cytokine production. Transplant immunology\| PubMed ID: 23651756	2013
Human secondary lymphoid organs typically contain polyclonally-activated proliferating regulatory T cells. Blood\| PubMed ID: 23950176	2013
Gateway to understanding microparticles: standardized isolation and identification of plasma membrane-derived vesicles. Nanomedicine (London, England)\| PubMed ID: 24074388	2013
Phosphatidylserine exposure on stored red blood cells as a parameter for donor-dependent variation in product quality. Blood transfusion = Trasfusione del sangue\| PubMed ID: 24120596	2014
Crosstalk between keratinocytes and T cells in a 3D microenvironment: a model to study inflammatory skin diseases. The Journal of investigative dermatology\| PubMed ID: 24121402	2014
Targeting PKC in human T cells using sotrastaurin (AEB071) preserves regulatory T cells and prevents IL-17 production. The Journal of investigative dermatology\| PubMed ID: 24192715	2014
Selective expansion of human natural killer cells leads to enhanced alloreactivity. Cellular & molecular immunology\| PubMed ID: 24240123	2014
Immune responses to stress after stress management training in patients with rheumatoid arthritis. Arthritis research & therapy\| PubMed ID: 24274618	2013
In vivo induction of cutaneous inflammation results in the accumulation of extracellular trap-forming neutrophils expressing RORγt and IL-17. The Journal of investigative dermatology\| PubMed ID: 24317395	2014
The impact of exercise on the variation of serum free light chains. Clinical chemistry and laboratory medicine\| PubMed ID: 24803612	2014
Immune responses to stress in rheumatoid arthritis and psoriasis. Rheumatology (Oxford, England)\| PubMed ID: 24850878	2014
Cellular sources of IL-17 in psoriasis: a paradigm shift? Experimental dermatology\| PubMed ID: 25039885	2014
Redefining Strategies to Introduce Tolerance-Inducing Cellular Therapy in Human beings to Combat Autoimmunity and Transplantation Reactions. Frontiers in immunology\| PubMed ID: 25177323	2014
The interplay between antiviral immunity and allo-immune reactivity after renal transplantation: consortium between the Centres Amsterdam, Leiden and Nijmegen (ALLOVIR). Transplant immunology\| PubMed ID: 25239648	2014
Balance of Treg versus T-effector cells during systemic treatment with adalimumab and topical treatment with calcipotriol-betamethasone dipropionate ointment. Experimental dermatology\| PubMed ID: 25355140	2015
Longitudinal analysis of T and B cell phenotype and function in renal transplant recipients with or without rituximab induction therapy. PloS one\| PubMed ID: 25393622	2014
Soluble CD30 does not predict late acute rejection or safe tapering of immunosuppression in renal transplantation. Transplant immunology\| PubMed ID: 25446808	2015
The number of CCR5 expressing CD4+ T lymphocytes is lower in HIV-infected long-term non-progressors with viral control compared to normal progressors: a cross-sectional study. BMC infectious diseases\| PubMed ID: 25495598	2014
Cytokine Release After Treatment With Rituximab in Renal Transplant Recipients. Transplantation\| PubMed ID: 25675201	2015
Prominent HLA-G Expression in Liver Disease But Not After Liver Transplantation. Transplantation\| PubMed ID: 25961490	2015
Low-affinity TCR engagement drives IL-2-dependent post-thymic maintenance of naive CD4+ T cells in aged humans. Aging cell\| PubMed ID: 26010129	2015
Quantitative measurement of immunoglobulins and free light chains using mass spectrometry. Analytical chemistry\| PubMed ID: 26168337	2015
The role of interleukin-1 beta in the pathophysiology of Schnitzler's syndrome. Arthritis research & therapy\| PubMed ID: 26198339	2015
Platelet-derived microparticles inhibit IL-17 production by regulatory T cells through P-selectin. Blood\| PubMed ID: 26903549	2016