Petra Boukamp

Genetics of Skin Carcinogenesis, German Cancer Research Center (DKFZ)

Affiliated withGerman Cancer Research Center (DKFZ)

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 15	2015

Other Publications

Article	Year
Dual regulation of telomerase activity through c-Myc-dependent inhibition and alternative splicing of hTERT. Journal of cell science\| PubMed ID: 11884529	2002
Human dermal fibroblasts escape from the long-term phenocopy of senescence induced by psoralen photoactivation. Experimental cell research\| PubMed ID: 11900490	2002
UV-B-type mutations and chromosomal imbalances indicate common pathways for the development of Merkel and skin squamous cell carcinomas. International journal of cancer. Journal international du cancer\| PubMed ID: 11992403	2002
The E6 and E7 proteins of the cutaneous human papillomavirus type 38 display transforming properties. Journal of virology\| PubMed ID: 12525654	2003
Constitutive overexpression of human telomerase reverse transcriptase but not c-myc blocks terminal differentiation in human HaCaT skin keratinocytes. The Journal of investigative dermatology\| PubMed ID: 12839571	2003
The three-dimensional organization of telomeres in the nucleus of mammalian cells. BMC biology\| PubMed ID: 15176976	2004
Authentic fibroblast matrix in dermal equivalents normalises epidermal histogenesis and dermoepidermal junction in organotypic co-culture. European journal of cell biology\| PubMed ID: 15679108	2004
Cell cycle-dependent 3D distribution of telomeres and telomere repeat-binding factor 2 (TRF2) in HaCaT and HaCaT-myc cells. European journal of cell biology\| PubMed ID: 15679112	2004
HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration. European journal of cell biology\| PubMed ID: 15679122	2004
Non-melanoma skin cancer: what drives tumor development and progression? Carcinogenesis\| PubMed ID: 15905207	2005
UV-induced skin cancer: similarities--variations. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG\| PubMed ID: 15967008	2005
Skin aging: a role for telomerase and telomere dynamics? Current molecular medicine\| PubMed ID: 15974870	2005
c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15983382	2005
Automatic telomere length measurements in interphase nuclei by IQ-FISH. Cytometry. Part A : the journal of the International Society for Analytical Cytology\| PubMed ID: 16228977	2005
Telomere-dependent chromosomal instability. The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research\| PubMed ID: 16358816	2005
Confocal reflection imaging of 3D fibrin polymers. Blood cells, molecules & diseases\| PubMed ID: 16488165	2006
Lack of nidogen-1 and -2 prevents basement membrane assembly in skin-organotypic coculture. The Journal of investigative dermatology\| PubMed ID: 17008882	2007
Reversion of tumor phenotype in surface transplants of skin SCC cells by scaffold-induced stroma modulation. Carcinogenesis\| PubMed ID: 17056607	2007
Epidermal homeostasis in long-term scaffold-enforced skin equivalents. The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research\| PubMed ID: 17069016	2006
Junctional basement membrane anomalies of skin and mucosa in lipoid proteinosis (hyalinosis cutis et mucosae). Journal of dermatological science\| PubMed ID: 17175139	2007
Telomeres rather than telomerase a key target for anti-cancer therapy? Experimental dermatology\| PubMed ID: 17181645	2007
A novel regulator of telomerase. S100A8 mediates differentiation-dependent and calcium-induced inhibition of telomerase activity in the human epidermal keratinocyte line HaCaT. The Journal of biological chemistry\| PubMed ID: 17197440	2007
The multi-step process of human skin carcinogenesis: a role for p53, cyclin D1, hTERT, p16, and TSP-1. European journal of cell biology\| PubMed ID: 17198740	2007
Effects of fibroblasts and microenvironment on epidermal regeneration and tissue function in long-term skin equivalents. European journal of cell biology\| PubMed ID: 17292509	2007
Improved alkaline comet assay protocol for adherent HaCaT keratinocytes to study UVA-induced DNA damage. Mutation research\| PubMed ID: 17509930	2007
Cathepsin B is essential for regeneration of scratch-wounded normal human epidermal keratinocytes. European journal of cell biology\| PubMed ID: 17651862	2007
Impairment of the telomere/telomerase system and genomic instability are associated with keratinocyte immortalization induced by the skin human papillomavirus type 38. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17898088	2008
Tumor immune escape by the loss of homeostatic chemokine expression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18025475	2007
A stable niche supports long-term maintenance of human epidermal stem cells in organotypic cultures. Stem cells (Dayton, Ohio)\| PubMed ID: 18653773	2008
Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1. Nucleic acids research\| PubMed ID: 18835851	2008
Dynamics of telomeres and promyelocytic leukemia nuclear bodies in a telomerase-negative human cell line. Molecular biology of the cell\| PubMed ID: 19211845	2009
Tissue context-activated telomerase in human epidermis correlates with little age-dependent telomere loss. Biochimica et biophysica acta\| PubMed ID: 19419690	2009
Aging and replicative senescence have related effects on human stem and progenitor cells. PloS one\| PubMed ID: 19513108	2009
Ewing's sarcoma cells with CD57-associated increase of tumorigenicity and with neural crest-like differentiation capacity. International journal of cancer. Journal international du cancer\| PubMed ID: 20104521	2010
Irradiation with heavy-ion particles changes the cellular distribution of human histone acetyltransferase HAT1. Molecular and cellular biochemistry\| PubMed ID: 20148353	2010
An inducible Tet-Off-H2B-GFP lentiviral reporter vector for detection and in vivo isolation of label-retaining cells. Experimental cell research\| PubMed ID: 20171964	2010
3D geometry-based quantification of colocalizations in multichannel 3D microscopy images of human soft tissue tumors. IEEE transactions on medical imaging\| PubMed ID: 20562043	2010
A decisive function of transforming growth factor-β/Smad signaling in tissue morphogenesis and differentiation of human HaCaT keratinocytes. Molecular biology of the cell\| PubMed ID: 21289094	2011
Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors. Cancer cell\| PubMed ID: 21397862	2011
UVA-induced epigenetic regulation of P16(INK4a) in human epidermal keratinocytes and skin tumor derived cells. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology\| PubMed ID: 21986889	2012
Stem cells of the human epidermis and their niche: composition and function in epidermal regeneration and carcinogenesis. Carcinogenesis\| PubMed ID: 22461521	2012
Different domains in nidogen-1 and nidogen-2 drive basement membrane formation in skin organotypic cocultures. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22623588	2012
Mechanism of the antiproliferative activity of some naphthalene diimide G-quadruplex ligands. Molecular pharmacology\| PubMed ID: 23188717	2013
An organotypic coculture model supporting proliferation and differentiation of medullary thymic epithelial cells and promiscuous gene expression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23269248	2013
WIF1 is expressed by stem cells of the human interfollicular epidermis and acts to suppress keratinocyte proliferation. The Journal of investigative dermatology\| PubMed ID: 23358094	2013
The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres. EMBO reports\| PubMed ID: 23797874	2013
The hallmarks of fibroblast ageing. Mechanisms of ageing and development\| PubMed ID: 24686308	2014
Frailty and telomere length: cross-sectional analysis in 3537 older adults from the ESTHER cohort. Experimental gerontology\| PubMed ID: 25150678	2014
Reproducibility of telomere length assessment: an international collaborative study. International journal of epidemiology\| PubMed ID: 25239152	2014
Wnt-3a-activated human fibroblasts promote human keratinocyte proliferation and matrix destruction. International journal of cancer. Journal international du cancer\| PubMed ID: 25403422	2015
Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin. The Journal of investigative dermatology\| PubMed ID: 25815425	2015
Three-Dimensional In Vitro Skin and Skin Cancer Models Based on Human Fibroblast-Derived Matrix. Tissue engineering. Part C, Methods\| PubMed ID: 25837604	2015
Subcellular Raman Microspectroscopy Imaging of Nucleic Acids and Tryptophan for Distinction of Normal Human Skin Cells and Tumorigenic Keratinocytes. Analytical chemistry\| PubMed ID: 25984831	2015