Lu Gan

Division of Biology, California Institute of Technology - Caltech

Affiliated withCalifornia Institute of Technology - Caltech

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 21	2010

Other Publications

Article	Year
HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain. The Journal of biological chemistry\| PubMed ID: 11889126	2002
HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis. Human molecular genetics\| PubMed ID: 12393793	2002
Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis. Biochemistry\| PubMed ID: 12403633	2002
Effects of selenium overexposure on glutathione peroxidase and thioredoxin reductase gene expressions and activities. Biological trace element research\| PubMed ID: 12449240	2002
The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase. Biochemistry\| PubMed ID: 12549902	2003
A polysaccharide-protein complex from Lycium barbarum upregulates cytokine expression in human peripheral blood mononuclear cells. European journal of pharmacology\| PubMed ID: 12826241	2003
Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking. The EMBO journal\| PubMed ID: 12839988	2003
Reversible anion exchanges between the layered organic-inorganic hybridized architectures: syntheses and structures of manganese(II) and copper(II) complexes containing novel tripodal ligand... Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 12916123	2003
IMP dehydrogenase: the dynamics of drug selectivity. Nucleic acids research. Supplement (2001)\| PubMed ID: 14510398	2003
Effects of gastric pacing on gastric emptying and plasma motilin. World journal of gastroenterology : WJG\| PubMed ID: 14760770	2004
Effect of surface chemistry on the rate of osseointegration of sintered porous-surfaced Ti-6Al-4V implants. The International journal of oral & maxillofacial implants\| PubMed ID: 14982351	2004
Enhanced expression of dopamine D(1) and glutamate NMDA receptors in dopamine D(4) receptor knockout mice. Journal of molecular neuroscience : MN\| PubMed ID: 14997010	2004
Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. International immunopharmacology\| PubMed ID: 15099534	2004
Calcium phosphate sol-gel-derived thin films on porous-surfaced implants for enhanced osteoconductivity. Part I: Synthesis and characterization. Biomaterials\| PubMed ID: 15110481	2004
Calcium phosphate sol-gel-derived thin films on porous-surfaced implants for enhanced osteoconductivity. Part II: Short-term in vivo studies. Biomaterials\| PubMed ID: 15110482	2004
Antagonistic effect of scutellarin on the toxicity of selenium in rat livers. Biological trace element research\| PubMed ID: 15131321	2004
Control of crosslinking by quaternary structure changes during bacteriophage HK97 maturation. Molecular cell\| PubMed ID: 15175152	2004
Evaluating interface strength of calcium phosphate sol-gel-derived thin films to Ti6Al4V substrate. Biomaterials\| PubMed ID: 15207465	2005
Evidence that a local refolding event triggers maturation of HK97 bacteriophage capsid. Journal of molecular biology\| PubMed ID: 15210344	2004
Huntingtin interacting protein 1 (HIP1) regulates clathrin assembly through direct binding to the regulatory region of the clathrin light chain. The Journal of biological chemistry\| PubMed ID: 15533941	2005
Effects of surface gastric pacing on gastric myoelectrical activity and plasma motilin in a canine model of gastric motility disorders. Chinese journal of digestive diseases\| PubMed ID: 15612658	2004
Membrane toxicity accounts for apoptosis induced by realgar nanoparticles in promyelocytic leukemia HL-60 cells. Biological trace element research\| PubMed ID: 15772436	2005
Huntingtin phosphorylation on serine 421 is significantly reduced in the striatum and by polyglutamine expansion in vivo. Human molecular genetics\| PubMed ID: 15843398	2005
Inhibitory effects of thioredoxin reductase antisense RNA on the growth of human hepatocellular carcinoma cells. Journal of cellular biochemistry\| PubMed ID: 16088946	2005
Pharmocokinetics and pharmacodynamics of single-dose triazolam: electroencephalography compared with the Digit-Symbol Substitution Test. British journal of clinical pharmacology\| PubMed ID: 16120062	2005
Membrane-associated cytotoxicity induced by realgar in promyelocytic leukemia HL-60 cells. Journal of ethnopharmacology\| PubMed ID: 16174554	2006
Repeated antipsychotic drug exposure in developing rats: dopamine receptor effects. Synapse (New York, N.Y.)\| PubMed ID: 16270300	2006
Puerarin protects rat pancreatic islets from damage by hydrogen peroxide. European journal of pharmacology\| PubMed ID: 16321378	2006
Large-scale purification and characterization of human parathyroid hormone-1 receptor stably expressed in HEK293S GnTI- cells. Protein expression and purification\| PubMed ID: 16376105	2006
Time-resolved molecular dynamics of bacteriophage HK97 capsid maturation interpreted by electron cryo-microscopy and X-ray crystallography. Journal of structural biology\| PubMed ID: 16427314	2006
Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: comparison with ritonavir. Clinical pharmacology and therapeutics\| PubMed ID: 16513448	2006
Reducing video-quality fluctuations for streaming scalable video using unequal error protection, retransmission, and interleaving. IEEE transactions on image processing : a publication of the IEEE Signal Processing Society\| PubMed ID: 16579371	2006
Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function. Nature neuroscience\| PubMed ID: 16699508	2006
RACK1, a novel hPER1-interacting protein. Journal of molecular neuroscience : MN\| PubMed ID: 16757810	2006
Studies on the interactions between DNA and PAMAM with fluorescent probe [Ru(phen)2 dppz]2+. Journal of pharmaceutical and biomedical analysis\| PubMed ID: 16872783	2007
IMP dehydrogenase: structural schizophrenia and an unusual base. Current opinion in chemical biology\| PubMed ID: 16919497	2006
Capsid conformational sampling in HK97 maturation visualized by X-ray crystallography and cryo-EM. Structure (London, England : 1993)\| PubMed ID: 17098191	2006
Regulations and roles of the interleukin-1 receptor associated kinases (IRAKs) in innate and adaptive immunity. Immunologic research\| PubMed ID: 17172653	2006
Low-power laser stimulation of tissue engineered cartilage tissue formed on a porous calcium polyphosphate scaffold. Lasers in surgery and medicine\| PubMed ID: 17252579	2007
In vitro cartilage tissue formation by Co-culture of primary and passaged chondrocytes. Tissue engineering\| PubMed ID: 17253927	2007
Undersampled boundary pre-/postfilters for low bit-rate DCT-based block coders. IEEE transactions on image processing : a publication of the IEEE Signal Processing Society\| PubMed ID: 17269636	2007
Wiener filter-based error resilient time-domain lapped transform. IEEE transactions on image processing : a publication of the IEEE Signal Processing Society\| PubMed ID: 17269641	2007
NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17329427	2007
Electron cryotomography sample preparation using the Vitrobot. Nature protocols\| PubMed ID: 17406539	2006
[Assessment of preclinical cognition impairment in hypertension patients with functional magnetic resonance imaging]. Zhonghua yi xue za zhi\| PubMed ID: 17425847	2007
Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth. Molecular immunology\| PubMed ID: 17477969	2007
Solution NMR studies of the maturation intermediates of a 13 MDa viral capsid. Journal of the American Chemical Society\| PubMed ID: 17536799	2007
[A study on the association of obstructive sleep apnea hypopnea syndrome with coronary atherosclerosis and coronary heart disease]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases\| PubMed ID: 17572995	2007
Activation of large-conductance calcium-activated potassium channels by puerarin: the underlying mechanism of puerarin-mediated vasodilation. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 17652634	2007
3-D ultrastructure of O. tauri: electron cryotomography of an entire eukaryotic cell. PloS one\| PubMed ID: 17710148	2007
[Identification of RACK1-PER1 protein interaction sites]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition\| PubMed ID: 17718421	2007
Correlation among obstructive sleep apnea syndrome, coronary atherosclerosis and coronary heart disease. Chinese medical journal\| PubMed ID: 17908485	2007
Monitoring bioaccumulation and toxic effects of hexachlorobenzene using the polyurethane foam unit method in the microbial communities of the Fuhe River, Wuhan. Journal of environmental sciences (China)\| PubMed ID: 17969649	2007
[Association of galectin-3 and E-cadherin expressions with lymph node metastasis of colon cancer]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University\| PubMed ID: 18024302	2007
Involvement of transcription factor activator protein-2alpha in doxazosin-induced HeLa cell apoptosis. Acta pharmacologica Sinica\| PubMed ID: 18358093	2008
An optimal exposure strategy for cryoprotected virus crystals with lattice constants greater than 1000 A. Journal of synchrotron radiation\| PubMed ID: 18421144	2008
Cartilage tissue formation using redifferentiated passaged chondrocytes in vitro. Tissue engineering. Part A\| PubMed ID: 18783319	2009
Role of NADPH-cytochrome P450 reductase and cytochrome-b5/NADH-b5 reductase in variability of CYP3A activity in human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals\| PubMed ID: 18838505	2009
Virus capsid expansion driven by the capture of mobile surface loops. Structure (London, England : 1993)\| PubMed ID: 18940605	2008
Nidus vespae protein inhibiting proliferation of HepG2 hepatoma cells through extracellular signal-regulated kinase signaling pathways and inducing G1 cell cycle arrest. Acta biochimica et biophysica Sinica\| PubMed ID: 18989579	2008
Molecular organization of Gram-negative peptidoglycan. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19033194	2008
A simple DNA extraction method for PCR amplification from dry seeds of Brassica napus. Pakistan journal of biological sciences: PJBS\| PubMed ID: 19070063	2007
A transcription-independent function of FOXO1 in inhibition of androgen-independent activation of the androgen receptor in prostate cancer cells. Cancer research\| PubMed ID: 19074897	2008
The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation. Journal of cellular biochemistry\| PubMed ID: 19115315	2009
An unexpected twist in viral capsid maturation. Nature\| PubMed ID: 19204733	2009
[Mode of intermediate and small enterprises employing occupational hygiene experts for supervision of the occupational work]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases\| PubMed ID: 19351482	2009
Improvement of neovascularization capacity of bone marrow mononuclear cells from diabetic mice by ex vivo pretreatment with resveratrol. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 19444278	2009
Dissociation of FKBP12.6 from ryanodine receptor type 2 is regulated by cyclic ADP-ribose but not beta-adrenergic stimulation in mouse cardiomyocytes. Cardiovascular research\| PubMed ID: 19578067	2009
An adenovirus-delivered peptide aptamer C1-1 targeting the core protein of hepatitis B virus inhibits viral DNA replication and production in vitro and in vivo. Peptides\| PubMed ID: 19619601	2009
Enhancement of BK(Ca) channel activity induced by hydrogen peroxide: involvement of lipid phosphatase activity of PTEN. Biochimica et biophysica acta\| PubMed ID: 19646416	2009
Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells. BMC cancer\| PubMed ID: 19671168	2009
Proteoglycan and collagen accumulation by passaged chondrocytes can be enhanced through side-by-side culture with primary chondrocytes. Tissue engineering. Part A\| PubMed ID: 19754222	2010
Inhibition of the androgen receptor as a novel mechanism of taxol chemotherapy in prostate cancer. Cancer research\| PubMed ID: 19826044	2009
IRAK-1 contributes to lipopolysaccharide-induced reactive oxygen species generation in macrophages by inducing NOX-1 transcription and Rac1 activation and suppressing the expression of antio... The Journal of biological chemistry\| PubMed ID: 19850916	2009
[Effects of temperature, moisture and forest succession on nitrogen mineralization in hillside red soils in mid-subtropical region, China]. Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban\| PubMed ID: 19899447	2009
Interleukin-1 Receptor-Associated Kinase-1 (IRAK-1) functionally associates with PKCepsilon and VASP in the regulation of macrophage migration. Molecular immunology\| PubMed ID: 20044140	2010
[Experimental research on biological responses of productive dusts from pottery factories and tungsten mines]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases\| PubMed ID: 20137385	2009
Relationship of daytime blood pressure and severity of obstructive sleep apnea among Chinese: a multi-center investigation in China. Chinese medical journal\| PubMed ID: 20137569	2010
The effect of oxidative stress in myocardial cell injury in mice exposed to chronic intermittent hypoxia. Chinese medical journal\| PubMed ID: 20137579	2010
Epigallocatechin-3-gallate (EGCG) attenuates inflammation in MRL/lpr mouse mesangial cells. Cellular & molecular immunology\| PubMed ID: 20140007	2010
Anti-inflammatory properties of bioactive titanium metals. Journal of biomedical materials research. Part A\| PubMed ID: 20205239	2010
Small Rho GTPase Rac1 determines human epidermal stem cell fate in vitro. International journal of molecular medicine\| PubMed ID: 20372815	2010
Biphasic effects of H(2)O(2) on BK(Ca) channels. Free radical research\| PubMed ID: 20560834	2010
Shikonin protects mouse brain against cerebral ischemia/reperfusion injury through its antioxidant activity. European journal of pharmacology\| PubMed ID: 20599918	2010
Mouse embryonic fibroblasts from CD38 knockout mice are resistant to oxidative stresses through inhibition of reactive oxygen species production and Ca(2+) overload. Biochemical and biophysical research communications\| PubMed ID: 20638362	2010
Transcription factor activator protein-2beta accelerates lipid accumulation in macrophages via enhancing the transcription of CD36. FEBS letters\| PubMed ID: 20659467	2010
Genome duplication effects on pollen development and the interrelated physiological substances in tetraploid rice with polyploid meiosis stability. Planta\| PubMed ID: 20717831	2010
[Promotion effect of stromal cell-derived factor 1 on the migration of epidermal stem cells in the healing process of frostbite-wound model ex vivo]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns\| PubMed ID: 20723424	2010
Chitosan as a condensing agent induces high gene transfection efficiency and low cytotoxicity of liposome. Journal of bioscience and bioengineering\| PubMed ID: 20851670	2011
Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2. Nature cell biology\| PubMed ID: 20935635	2010
Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20980587	2010
Effects of lysophosphatidic acid and its receptors LPAâ…“ on radiation pneumonitis. Oncology reports\| PubMed ID: 21042747	2010
In vivo assembly of an archaeal virus studied with whole-cell electron cryotomography. Structure (London, England : 1993)\| PubMed ID: 21134637	2010
Resistance to docetaxel-induced apoptosis in prostate cancer cells by p38/p53/p21 signaling. The Prostate\| PubMed ID: 21229560	2011
Low-dose endotoxin induces inflammation by selectively removing nuclear receptors and activating CCAAT/enhancer-binding protein Î´. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21357541	2011
Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases. Arthritis research & therapy\| PubMed ID: 21521520	2011
Blockade of lysophosphatidic acid receptors LPAR1/3 ameliorates lung fibrosis induced by irradiation. Biochemical and biophysical research communications\| PubMed ID: 21545790	2011
Role of cellular uptake in the reversal of multidrug resistance by PEG-b-PLA polymeric micelles. Biomaterials\| PubMed ID: 21546083	2011
Distribution of microfossils within polymetallic nodules: biogenic clusters within manganese layers. Marine biotechnology (New York, N.Y.)\| PubMed ID: 21626367	2012
Resistance to docetaxel-induced apoptosis in prostate cancer cells by p38/p53/p21 signaling. The Prostate\| PubMed ID: 21656826	2011
[Modulatory effect of Rac1 protein on epidermal stem cells migration during wound healing]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns\| PubMed ID: 21781463	2011
Disruption of CD38 gene enhances cardiac functions by elevating serum testosterone in the male null mice. Life sciences\| PubMed ID: 21840325	2011
Laparoscopic radical correction combined with extensive lymphadenectomy and pelvic autonomic nerve preservation for mid-to-low rectal cancer. Clinical colorectal cancer\| PubMed ID: 21855040	2011
The Unique Invention of the Siliceous Sponges: Their Enzymatically Made Bio-Silica Skeleton. Progress in molecular and subcellular biology\| PubMed ID: 21877269	2011
State of the art: what we know about infectious agents and myositis. Current opinion in rheumatology\| PubMed ID: 21885972	2011
Organization of the smallest eukaryotic spindle. Current biology : CB\| PubMed ID: 21906950	2011
The largest Bio-Silica Structure on Earth: The Giant Basal Spicule from the Deep-Sea Glass Sponge Monorhaphis chuni. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 21941585	2011
Plasma proteomic profiles from disease-discordant monozygotic twins suggest that molecular pathways are shared in multiple systemic autoimmune diseases* Arthritis research & therapy\| PubMed ID: 22044644	2011
Electron tomography of cells. Quarterly reviews of biophysics\| PubMed ID: 22082691	2011
The incorporation of a zone of calcified cartilage improves the interfacial shear strength between in vitro-formed cartilage and the underlying substrate. Acta biomaterialia\| PubMed ID: 22222151	2011
Vigabatrin versus carbamazepine monotherapy for epilepsy. Cochrane database of systematic reviews (Online)\| PubMed ID: 22258989	2012