Leandro Castellano

Department of Surgery and Cancer, Imperial College London

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 114	2015

Other Publications

Article	Year
Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia. Blood\| PubMed ID: 17327404	2007
Bendamustine as a model for the activity of alkylating agents. Future oncology (London, England)\| PubMed ID: 18518757	2008
CK1delta modulates the transcriptional activity of ERalpha via AIB1 in an estrogen-dependent manner and regulates ERalpha-AIB1 interactions. Nucleic acids research\| PubMed ID: 19339517	2009
The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19706389	2009
No evidence for a viral association or aetiology in pancreatic cancer. Molecular immunology\| PubMed ID: 19932507	2010
No evidence for a polyomavirus association or aetiology in AIDS-associated nonsmall cell lung cancer. AIDS (London, England)\| PubMed ID: 20400884	2010
Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer. Nature medicine\| PubMed ID: 21602804	2011
Determination of cut-offs for circulating tumor cell measurement in metastatic cancer. Expert review of anticancer therapy\| PubMed ID: 21929309	2011
microRNAs as markers of survival and chemoresistance in pancreatic ductal adenocarcinoma. Expert review of anticancer therapy\| PubMed ID: 22117151	2011
Integrated analysis of miRNA and mRNA profiles enables target acquisition in human cancers. Expert review of anticancer therapy\| PubMed ID: 22369323	2012
MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors. PloS one\| PubMed ID: 22384141	2012
The clinico-pathologic role of microRNAs miR-9 and miR-151-5p in breast cancer metastasis. Molecular diagnosis & therapy\| PubMed ID: 22489664	2012
miRNAs in breast cancer: ready for real time? Pharmacogenomics\| PubMed ID: 22515613	2012
Transcriptome-level microarray expression profiling implicates IGF-1 and Wnt signalling dysregulation in the pathogenesis of thyroid-associated orbitopathy. Journal of clinical pathology\| PubMed ID: 22554965	2012
Retinoblastoma protein determines aggressiveness in triple-negative breast cancer. Expert review of anticancer therapy\| PubMed ID: 22594893	2012
The role of miR-10b in metastatic pancreatic ductal adenocarcinoma. Surgery\| PubMed ID: 22682079	2012
Loss of miR-126 is crucial to pancreatic cancer progression. Expert review of anticancer therapy\| PubMed ID: 22845403	2012
Breast cancer treatment and adverse cardiac events: what are the molecular mechanisms?. Cardiology\| PubMed ID: 22907032	2012
Defining a prognostic molecular profile for ductal adenocarcinoma of the pancreas highlights known key signaling pathways. Expert review of anticancer therapy\| PubMed ID: 23176615	2012
Towards a clinical use of miRNAs in pancreatic cancer biopsies. Expert review of molecular diagnostics\| PubMed ID: 23256701	2013
Altered expression of the miRNA processing endoribonuclease Dicer has prognostic significance in human cancers. Expert review of anticancer therapy\| PubMed ID: 23259424	2013
Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues. Nucleic acids research\| PubMed ID: 23325850	2013
Circulating molecular markers in pancreatic cancer: ready for clinical use? Future oncology (London, England)\| PubMed ID: 23414463	2013
Blood-based miRNAs as noninvasive diagnostic and surrogative biomarkers in colorectal cancer. Expert review of molecular diagnostics\| PubMed ID: 23477554	2013
miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts. Nucleic acids research\| PubMed ID: 23580553	2013
Distinct miRNA profiles are associated with malignant transformation of pancreatic cystic tumors revealing potential biomarkers for clinical use. Expert review of molecular diagnostics\| PubMed ID: 23638815	2013
Circulating peripheral blood mononuclear cells exhibit altered miRNA expression patterns in pancreatic cancer. Expert review of molecular diagnostics\| PubMed ID: 23782250	2013
The p53 miRNA interactome and its potential role in the cancer clinic. Epigenomics\| PubMed ID: 23895654	2013
Emerging roles of competing endogenous RNAs in cancer: insights from the regulation of PTEN. Molecular and cellular biology\| PubMed ID: 23918803	2013
Downregulation of microRNA-515-5p by the estrogen receptor modulates sphingosine kinase 1 and breast cancer cell proliferation. Cancer research\| PubMed ID: 23928990	2013
MicroRNA-23b regulates cellular architecture and impairs motogenic and invasive phenotypes during cancer progression. Bioarchitecture\| PubMed ID: 24002530	2013
MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression. Gastroenterology\| PubMed ID: 24120476	2014
Cell-free DNA for the detection of pancreatic, liver and upper gastrointestinal cancers: has progress been made? Future oncology (London, England)\| PubMed ID: 24295416	2013
A microRNA meta-signature for pancreatic ductal adenocarcinoma. Expert review of molecular diagnostics\| PubMed ID: 24575833	2014
Reduced dissemination of circulating tumor cells with no-touch isolation surgical technique in patients with pancreatic cancer. JAMA surgery\| PubMed ID: 24599353	2014
miR-15b and miR-17 Are Tumor-Derived Plasma MicroRNAs Dysregulated in Colorectal Neoplasia. Annals of surgery\| PubMed ID: 24646542	2014
Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets. PloS one\| PubMed ID: 24670416	2014
Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer. PloS one\| PubMed ID: 24926850	2014
miR-211 modulates gemcitabine activity through downregulation of ribonucleotide reductase and inhibits the invasive behavior of pancreatic cancer cells. Nucleosides, nucleotides & nucleic acids\| PubMed ID: 24940696	2014
5' isomiR variation is of functional and evolutionary importance. Nucleic acids research\| PubMed ID: 25056318	2014
Noncoding RNAs and the control of hormonal signaling via nuclear receptor regulation. Journal of molecular endocrinology\| PubMed ID: 25062739	2014
The germline of the malaria mosquito produces abundant miRNAs, endo-siRNAs, piRNAs and 29-nt small RNAs. BMC genomics\| PubMed ID: 25766668	2015