V. Wee Yong

Department of Clinical Neurosciences, Hotchkiss Brain Institute at University of Calgary

Affiliated withHotchkiss Brain Institute at University of Calgary University of Calgary

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 78	2015
Publication title	2024

Other Publications

Article	Year
A dialog between glioma and microglia that promotes tumor invasiveness through the CCL2/CCR2/interleukin-6 axis. Carcinogenesis\| PubMed ID: 22159219	2012
A novel anti-EMMPRIN function-blocking antibody reduces T cell proliferation and neurotoxicity: relevance to multiple sclerosis. Journal of neuroinflammation\| PubMed ID: 22480370	2012
Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosis. Glia\| PubMed ID: 22499213	2012
Results of a phase II placebo-controlled randomized trial of minocycline in acute spinal cord injury. Brain : a journal of neurology\| PubMed ID: 22505632	2012
Kinetics of proinflammatory monocytes in a model of multiple sclerosis and its perturbation by laquinimod. The American journal of pathology\| PubMed ID: 22749771	2012
Immune cell infiltrates in atypical teratoid/rhabdoid tumors. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques\| PubMed ID: 22931701	2012
Prolactin in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 22933621	2013
Susceptibility-weighted imaging in the experimental autoimmune encephalomyelitis model of multiple sclerosis indicates elevated deoxyhemoglobin, iron deposition and demyelination. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 23027879	2013
Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination. Annals of neurology\| PubMed ID: 23034914	2012
Remyelination therapy for multiple sclerosis. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 23070731	2013
Cortical remyelination: a new target for repair therapies in multiple sclerosis. Annals of neurology\| PubMed ID: 23076662	2012
Review: Endocrine disrupting chemicals and immune responses: a focus on bisphenol-A and its potential mechanisms. Molecular immunology\| PubMed ID: 23123408	2013
Environmental factors and their regulation of immunity in multiple sclerosis. Journal of the neurological sciences\| PubMed ID: 23154080	2013
Reply: To PMID 23034914. Annals of neurology\| PubMed ID: 23424070	2013
Overcoming neurite-inhibitory chondroitin sulfate proteoglycans in the astrocyte matrix. Glia\| PubMed ID: 23554135	2013
Extracellular matrix metalloproteinase inducer shows active perivascular cuffs in multiple sclerosis. Brain : a journal of neurology\| PubMed ID: 23687119	2013
A prospective evaluation of the temporal matrix metalloproteinase response after severe traumatic brain injury in humans. Journal of neurotrauma\| PubMed ID: 23725031	2013
Resistance to oncolytic myxoma virus therapy in nf1(-/-)/trp53(-/-) syngeneic mouse glioma models is independent of anti-viral type-I interferon. PloS one\| PubMed ID: 23762429	2013
Association between the cerebral inflammatory and matrix metalloproteinase responses after severe traumatic brain injury in humans. Journal of neurotrauma\| PubMed ID: 23799281	2013
The benefits and detriments of macrophages/microglia in models of multiple sclerosis. Clinical & developmental immunology\| PubMed ID: 23840244	2013
Reduction of microglial activity in a model of multiple sclerosis by dipyridamole. Journal of neuroinflammation\| PubMed ID: 23866809	2013
Treatment trials in progressive MS--current challenges and future directions. Nature reviews. Neurology\| PubMed ID: 23897406	2013
Pathophysiology of the brain extracellular matrix: a new target for remyelination. Nature reviews. Neuroscience\| PubMed ID: 23985834	2013
Screening for inhibitors of microglia to reduce neuroinflammation. CNS & neurological disorders drug targets\| PubMed ID: 24047520	2013
High-resolution fluorescence microscopy of myelin without exogenous probes. NeuroImage\| PubMed ID: 24188810	2014
The regulation of reactive changes around multiple sclerosis lesions by phosphorylated signal transducer and activator of transcription. Journal of neuropathology and experimental neurology\| PubMed ID: 24226263	2013
Active inflammation increases the heterogeneity of MRI texture in mice with relapsing experimental allergic encephalomyelitis. Magnetic resonance imaging\| PubMed ID: 24246391	2014
Using magnetic resonance imaging in animal models to guide drug development in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 24263386	2014
Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells. Nature neuroscience\| PubMed ID: 24316889	2014
Toll-like receptor 2-mediated alternative activation of microglia is protective after spinal cord injury. Brain : a journal of neurology\| PubMed ID: 24369381	2014
Remyelination after spinal cord injury: is it a target for repair? Progress in neurobiology\| PubMed ID: 24582777	2014
Patrolling monocytes play a critical role in CX3CR1-mediated neuroprotection during excitotoxicity. Brain structure & function\| PubMed ID: 24706067	2014
Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome. Journal of neurology, neurosurgery, and psychiatry\| PubMed ID: 24935984	2015
Understanding disease processes in multiple sclerosis through magnetic resonance imaging studies in animal models. NeuroImage. Clinical\| PubMed ID: 24936425	2014
Iron in multiple sclerosis: roles in neurodegeneration and repair. Nature reviews. Neurology\| PubMed ID: 25002107	2014
Interactions between microglia and T cells in multiple sclerosis pathobiology. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research\| PubMed ID: 25084178	2014
Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells. Annals of neurosciences\| PubMed ID: 25206040	2013
Changes in tissue directionality reflect differences in myelin content after demyelination in mice spinal cords. Journal of structural biology\| PubMed ID: 25281497	2014
Cellular factors promoting resistance to effective treatment of glioma with oncolytic myxoma virus. Cancer research\| PubMed ID: 25336188	2014
The battle for the brain: Brain tumor-initiating cells vs. microglia/macrophages. Oncoimmunology\| PubMed ID: 25340004	2014
Laquinimod reduces neuroaxonal injury through inhibiting microglial activation. Annals of clinical and translational neurology\| PubMed ID: 25356411	2014
Stimulation of monocytes, macrophages, and microglia by amphotericin B and macrophage colony-stimulating factor promotes remyelination. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25609628	2015
EMMPRIN, an upstream regulator of MMPs, in CNS biology. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 25644103	2015
ADAM-9 is a novel mediator of tenascin-C-stimulated invasiveness of brain tumor-initiating cells. Neuro-oncology\| PubMed ID: 25646025	2015
The promise of futility trials in neurological diseases. Nature reviews. Neurology\| PubMed ID: 25776824	2015
Inefficient clearance of myelin debris by microglia impairs remyelinating processes. The Journal of experimental medicine\| PubMed ID: 25779633	2015
Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 10493747	1999
Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression. Molecular and cellular biology\| PubMed ID: 10848585	2000
Metalloproteinases in biology and pathology of the nervous system. Nature reviews. Neuroscience\| PubMed ID: 11433375	2001
P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11549724	2001
The expression of matrix metalloproteinase-12 by oligodendrocytes regulates their maturation and morphological differentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15342725	2004
Myelin formation during development of the CNS is delayed in matrix metalloproteinase-9 and -12 null mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16495447	2006
White matter plasticity and enhanced remyelination in the maternal CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17314279	2007
Targeting MMPs in acute and chronic neurological conditions. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 17920539	2007
Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19158301	2009
Matrix metalloproteinase-12 deficiency worsens relapsing-remitting experimental autoimmune encephalomyelitis in association with cytokine and chemokine dysregulation. The American journal of pathology\| PubMed ID: 19218336	2009
Multiexponential T2 and magnetization transfer MRI of demyelination and remyelination in murine spinal cord. NeuroImage\| PubMed ID: 19349232	2009
Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19815532	2009
Taking advantage of the systemic immune system to cure brain diseases. Neuron\| PubMed ID: 19840549	2009
Reduction of protein kinase C delta attenuates tenascin-C stimulated glioma invasion in three-dimensional matrix. Carcinogenesis\| PubMed ID: 19965895	2010
The interplay between the immune and central nervous systems in neuronal injury. Neurology\| PubMed ID: 20038767	2010
Improving outcomes of neuroprotection by minocycline: guides from cell culture and intracerebral hemorrhage in mice. The American journal of pathology\| PubMed ID: 20110416	2010
Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties. Neuro-oncology\| PubMed ID: 20308313	2010
Reduction of PrP(C) in human cerebrospinal fluid after spinal cord injury. Prion\| PubMed ID: 20418657	2010
Neuroinflammation and demyelination in multiple sclerosis after allogeneic hematopoietic stem cell transplantation. Archives of neurology\| PubMed ID: 20558390	2010
Cleavage of osteopontin by matrix metalloproteinase-12 modulates experimental autoimmune encephalomyelitis disease in C57BL/6 mice. The American journal of pathology\| PubMed ID: 20651245	2010
The many faces of EMMPRIN - roles in neuroinflammation. Biochimica et biophysica acta\| PubMed ID: 20674741	2011
EMMPRIN: a novel regulator of leukocyte transmigration into the CNS in multiple sclerosis and experimental autoimmune encephalomyelitis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21228176	2011
Analysis of the mitochondrial proteome in multiple sclerosis cortex. Biochimica et biophysica acta\| PubMed ID: 21295140	2011
Predominance of Th2 polarization by vitamin D through a STAT6-dependent mechanism. Journal of neuroinflammation\| PubMed ID: 21605467	2011
The good, the bad and the ugly. Macrophages/microglia with a focus on myelin repair. Frontiers in bioscience (Scholar edition)\| PubMed ID: 21622236	2011
Chondroitin sulphate proteoglycans: extracellular matrix proteins that regulate immunity of the central nervous system. Autoimmunity reviews\| PubMed ID: 21664302	2011
[Promoting remyelination by reducing an inhibitory microenvironment]. Rinsho shinkeigaku = Clinical neurology\| PubMed ID: 21921479	2010
Prolactin in combination with interferon-β reduces disease severity in an animal model of multiple sclerosis. Journal of neuroinflammation\| PubMed ID: 25889599	2015
The role of EMMPRIN in T cell biology and immunological diseases. Journal of leukocyte biology\| PubMed ID: 25977287	2015
Detecting deoxyhemoglobin in spinal cord vasculature of the experimental autoimmune encephalomyelitis mouse model of multiple sclerosis using susceptibility MRI and hyperoxygenation. PloS one\| PubMed ID: 25992667	2015
Fluorescent Phosphorus Dendrimer as a Spectral Nanosensor for Macrophage Polarization and Fate Tracking in Spinal Cord Injury. Macromolecular bioscience\| PubMed ID: 26175127	2015
1,25-Dihydroxyvitamin D3 Protects against Immune-Mediated Killing of Neurons in Culture and in Experimental Autoimmune Encephalomyelitis. PloS one\| PubMed ID: 26679341	2015
Multi-scale MRI spectrum detects differences in myelin integrity between MS lesion types. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 26754802	2016
Monocytes increase human cardiac myofibroblast-mediated extracellular matrix remodeling through TGF-β1. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26801303	2016
Expanding antigen-specific regulatory networks to treat autoimmunity. Nature\| PubMed ID: 26886799	2016
Immunosenescence of microglia and macrophages: impact on the ageing central nervous system. Brain : a journal of neurology\| PubMed ID: 26912633	2016
Activity-Dependent and Experience-Driven Myelination Provide New Directions for the Management of Multiple Sclerosis. Trends in neurosciences\| PubMed ID: 27113322	2016
Demyelination induces transport of ribosome-containing vesicles from glia to axons: evidence from animal models and MS patient brains. Molecular biology reports\| PubMed ID: 27115494	2016
An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination. Nature communications\| PubMed ID: 27115988	2016
Regenerative Capacity of Macrophages for Remyelination. Frontiers in cell and developmental biology\| PubMed ID: 27243011	2016
Myeloid cells - targets of medication in multiple sclerosis. Nature reviews. Neurology\| PubMed ID: 27514287	2016
MRI monitoring of monocytes to detect immune stimulating treatment response in brain tumor. Neuro-oncology\| PubMed ID: 27571884	2017
Evaluating Soluble EMMPRIN as a Marker of Disease Activity in Multiple Sclerosis: Studies of Serum and Cerebrospinal Fluid. PloS one\| PubMed ID: 27727297	2016
Impact of Minocycline on Extracellular Matrix Metalloproteinase Inducer, a Factor Implicated in Multiple Sclerosis Immunopathogenesis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 27733550	2016
T Cell Exhaustion in Glioblastoma: Intricacies of Immune Checkpoints. Trends in immunology\| PubMed ID: 27964820	2017
Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis. The Journal of cell biology\| PubMed ID: 28264914	2017
Glioblastoma-associated microglia and macrophages: targets for therapies to improve prognosis. Brain : a journal of neurology\| PubMed ID: 28334886	2017
Activation of NOTCH Signaling by Tenascin-C Promotes Growth of Human Brain Tumor-Initiating Cells. Cancer research\| PubMed ID: 28416488	2017
Gestational bisphenol-A exposure lowers the threshold for autoimmunity in a model of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28439012	2017
Stop inflammation and you stop neurodegeneration in MS - YES. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 28463075	2017
Remyelination therapies: a new direction and challenge in multiple sclerosis. Nature reviews. Drug discovery\| PubMed ID: 28685761	2017
Unexpected additive effects of minocycline and hydroxychloroquine in models of multiple sclerosis: Prospective combination treatment for progressive disease? Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 28857721	2018
Mechanisms of lysophosphatidylcholine-induced demyelination: A primary lipid disrupting myelinopathy. Glia\| PubMed ID: 29068088	2018
Systematic screening of generic drugs for progressive multiple sclerosis identifies clomipramine as a promising therapeutic. Nature communications\| PubMed ID: 29259169	2017
Deficient Surveillance and Phagocytic Activity of Myeloid Cells Within Demyelinated Lesions in Aging Mice Visualized by Live Multiphoton Imaging. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 29363580	2018
Chondroitin sulfate proteoglycans as novel drivers of leucocyte infiltration in multiple sclerosis. Brain : a journal of neurology\| PubMed ID: 29506186	2018
The extracellular matrix: Focus on oligodendrocyte biology and targeting CSPGs for remyelination therapies. Glia\| PubMed ID: 29603376	2018
Pro-inflammatory roles of chondroitin sulfate proteoglycans in disorders of the central nervous system. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 29702175	2018
MR Imaging of Tumor-Associated Macrophages: The Next Frontier in Cancer Imaging. Magnetic resonance insights\| PubMed ID: 29780249	2018
Expanding the Potential Therapeutic Options for Remote Ischemic Preconditioning: Use in Multiple Sclerosis. Frontiers in neurology\| PubMed ID: 29971043	2018
Cerebrospinal Fluid Biomarkers in Human Spinal Cord Injury from a Phase II Minocycline Trial. Journal of neurotrauma\| PubMed ID: 30074872	2018
Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1α. Cell reports\| PubMed ID: 30232000	2018
Brain tumor-initiating cells export tenascin-C associated with exosomes to suppress T cell activity. Oncoimmunology\| PubMed ID: 30288344	2018
Focus on the gut-brain axis: Multiple sclerosis, the intestinal barrier and the microbiome. World journal of gastroenterology\| PubMed ID: 30310254	2018
Microglia induces Gas1 expression in human brain tumor-initiating cells to reduce tumorigenecity. Scientific reports\| PubMed ID: 30327548	2018
Efficacy of Minocycline in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Rodent and Clinical Studies. Frontiers in neurology\| PubMed ID: 30619060	2018
The benefits of neuroinflammation for the repair of the injured central nervous system. Cellular & molecular immunology\| PubMed ID: 30874626	2019
Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis. The Journal of clinical investigation\| PubMed ID: 31112527	2019
Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma. Oncotarget\| PubMed ID: 31139325	2019
Domperidone-induced elevation of serum prolactin levels and immune response in multiple sclerosis. Journal of neuroimmunology\| PubMed ID: 31174092	2019
Central nervous system targeted autoimmunity causes regional atrophy: a 9.4T MRI study of the EAE mouse model of Multiple Sclerosis. Scientific reports\| PubMed ID: 31186441	2019
Biomarkers of intestinal barrier function in multiple sclerosis are associated with disease activity. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 31317818	2020
Progressive multiple sclerosis: from pathophysiology to therapeutic strategies. Nature reviews. Drug discovery\| PubMed ID: 31399729	2019
Targeting the Chondroitin Sulfate Proteoglycans: Evaluating Fluorinated Glucosamines and Xylosides in Screens Pertinent to Multiple Sclerosis. ACS central science\| PubMed ID: 31404231	2019
Exercise in multiple sclerosis and its models: Focus on the central nervous system outcomes. Journal of neuroscience research\| PubMed ID: 31486115	2020
When encephalitogenic T cells collaborate with microglia in multiple sclerosis. Nature reviews. Neurology\| PubMed ID: 31527807	2019
2-arachidonoylglycerol reduces chondroitin sulphate proteoglycan production by astrocytes and enhances oligodendrocyte differentiation under inhibitory conditions. Glia\| PubMed ID: 31894889	2020
Microglia and macrophage phenotypes in intracerebral haemorrhage injury: therapeutic opportunities. Brain : a journal of neurology\| PubMed ID: 31919518	2020
Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion. Science advances\| PubMed ID: 31998844	2020
Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. Acta neuropathologica\| PubMed ID: 32030468	2020
Demeclocycline Reduces the Growth of Human Brain Tumor-Initiating Cells: Direct Activity and Through Monocytes. Frontiers in immunology\| PubMed ID: 32153581	2020
Correction to: Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. Acta neuropathologica\| PubMed ID: 32211925	2020
Control of brain tumor growth by reactivating myeloid cells with niacin. Science translational medicine\| PubMed ID: 32238578	2020
The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination. Journal of neuroinflammation\| PubMed ID: 32703234	2020
Author Correction: Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy. Nature communications\| PubMed ID: 32769982	2020
Beyond barrier functions: Roles of pericytes in homeostasis and regulation of neuroinflammation. Journal of neuroscience research\| PubMed ID: 32815569	2020
Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression. Nature communications\| PubMed ID: 33020472	2020
Metabolic needs of brain-infiltrating leukocytes and microglia in multiple sclerosis. Journal of neurochemistry\| PubMed ID: 33025576	2021
Aging-Exacerbated Acute Axon and Myelin Injury Is Associated with Microglia-Derived Reactive Oxygen Species and Is Alleviated by the Generic Medication Indapamide. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 33060175	2020
Exercise and the brain in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 33124511	2022
Neuroinflammation in intracerebral haemorrhage: immunotherapies with potential for translation. The Lancet. Neurology\| PubMed ID: 33212054	2020
Neuregulin-1 beta 1 is implicated in pathogenesis of multiple sclerosis. Brain : a journal of neurology\| PubMed ID: 33313801	2021
Intracerebral haemorrhage: from clinical settings to animal models. Stroke and vascular neurology\| PubMed ID: 33376200	2020
Combination of Hydroxychloroquine and Indapamide Attenuates Neurodegeneration in Models Relevant to Multiple Sclerosis. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 33410109	2021
Multimodal peripheral fluid biomarker analysis in clinically isolated syndrome and early multiple sclerosis. Multiple sclerosis and related disorders\| PubMed ID: 33581614	2021
Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia. Nature neuroscience\| PubMed ID: 33603230	2021
Circadian disruption in mice through chronic jet lag-like conditions modulates molecular profiles of cancer in nucleus accumbens and prefrontal cortex. Carcinogenesis\| PubMed ID: 33608694	2021
Fibrinogen in the glioblastoma microenvironment contributes to the invasiveness of brain tumor-initiating cells. Brain pathology (Zurich, Switzerland)\| PubMed ID: 33694259	2021
Harnessing the Benefits of Neuroinflammation: Generation of Macrophages/Microglia with Prominent Remyelinating Properties. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 33712513	2021
Exercise rapidly alters proteomes in mice following spinal cord demyelination. Scientific reports\| PubMed ID: 33790323	2021
The extracellular matrix as modifier of neuroinflammation and remyelination in multiple sclerosis. Brain : a journal of neurology\| PubMed ID: 33889940	2021
Repurposing Domperidone in Secondary Progressive Multiple Sclerosis: A Simon 2-Stage Phase 2 Futility Trial. Neurology\| PubMed ID: 34038379	2021
The combination of deferoxamine and minocycline strengthens neuroprotective effect on acute intracerebral hemorrhage in rats. Neurological research\| PubMed ID: 34107863	2021
Obesity in acute ischaemic stroke patients treated with intravenous thrombolysis therapy. Neurological research\| PubMed ID: 34112057	2023
An X-ray for myelin. Trends in neurosciences\| PubMed ID: 34148671	2021
Susceptibility weighted imaging detects prominent veins that precede or coincide with maximal motor disability in a model of multiple sclerosis: A pilot study. Multiple sclerosis and related disorders\| PubMed ID: 34243102	2021
Does chronic jet lag increase risk of cancer? Aging\| PubMed ID: 34586082	2021
Hydroxychloroquine for Primary Progressive Multiple Sclerosis. Annals of neurology\| PubMed ID: 34590328	2021
Studying the microglia response to oxidized phosphatidylcholine in primary mouse neuron culture and mouse spinal cord. STAR protocols\| PubMed ID: 34622221	2021
Neuroprotection of minocycline by inhibition of extracellular matrix metalloproteinase inducer expression following intracerebral hemorrhage in mice. Neuroscience letters\| PubMed ID: 34666120	2021
Central Nervous System Tissue Regeneration after Intracerebral Hemorrhage: The Next Frontier. Cells\| PubMed ID: 34685493	2021
MedXercise: a promising strategy to promote remyelination. Current opinion in pharmacology\| PubMed ID: 34688996	2021
The Canadian prospective cohort study to understand progression in multiple sclerosis (CanProCo): rationale, aims, and study design. BMC neurology\| PubMed ID: 34706670	2021
Mechanism-based criteria to improve therapeutic outcomes in progressive multiple sclerosis. Nature reviews. Neurology\| PubMed ID: 34732831	2022
PD-1 independent of PD-L1 ligation promotes glioblastoma growth through the NFκB pathway. Science advances\| PubMed ID: 34739319	2021
Quantitative analysis of spinal cord neuropathology in experimental autoimmune encephalomyelitis. Journal of neuroimmunology\| PubMed ID: 34823122	2022
B cells in central nervous system disease: diversity, locations and pathophysiology. Nature reviews. Immunology\| PubMed ID: 34903877	2022
Gap Junctions and Hemichannels Composed of Connexins and Pannexins Mediate the Secondary Brain Injury Following Intracerebral Hemorrhage. Biology\| PubMed ID: 35053024	2021
Remyelination trial failures: Repercussions of ignoring neurorehabilitation and exercise in repair. Multiple sclerosis and related disorders\| PubMed ID: 35066276	2022
A Distinct Extract Prevents Iron Neurotoxicity, a Driver of Multiple Sclerosis Pathology. Cells\| PubMed ID: 35159249	2022
Modes of Brain Cell Death Following Intracerebral Hemorrhage. Frontiers in cellular neuroscience\| PubMed ID: 35185473	2022
Vildagliptin improves neurological function by inhibiting apoptosis and ferroptosis following intracerebral hemorrhage in mice. Neuroscience letters\| PubMed ID: 35304193	2022
Exercise training in multiple sclerosis. The Lancet. Neurology\| PubMed ID: 35305335	2022
Oxidative Stress Following Intracerebral Hemorrhage: From Molecular Mechanisms to Therapeutic Targets. Frontiers in immunology\| PubMed ID: 35355999	2022
Matrix Metalloproteinase-9 as an Important Contributor to the Pathophysiology of Depression. Frontiers in neurology\| PubMed ID: 35370878	2022
Oxidized phospholipids as novel mediators of neurodegeneration. Trends in neurosciences\| PubMed ID: 35393134	2022
Revisiting Minocycline in Intracerebral Hemorrhage: Mechanisms and Clinical Translation. Frontiers in immunology\| PubMed ID: 35401553	2022
Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination. Nature communications\| PubMed ID: 35508608	2022
EMMPRIN Promotes the Expression of MMP-9 and Exacerbates Neurological Dysfunction in a Mouse Model of Intracerebral Hemorrhage. Neurochemical research\| PubMed ID: 35608790	2022
Microglia in multiple sclerosis - pathogenesis and imaging. Current opinion in neurology\| PubMed ID: 35674072	2022
Thermoregulatory dynamics reveal sex-specific inflammatory responses to experimental autoimmune encephalomyelitis in mice: Implications for multiple sclerosis-induced fatigue in females. Brain, behavior, & immunity - health\| PubMed ID: 35677535	2022
Necrosulfonamide Alleviates Acute Brain Injury of Intracerebral Hemorrhage Inhibiting Inflammation and Necroptosis. Frontiers in molecular neuroscience\| PubMed ID: 35721316	2022
Iron Neurotoxicity and Protection by Deferoxamine in Intracerebral Hemorrhage. Frontiers in molecular neuroscience\| PubMed ID: 35782383	2022
Neuroprotection by Ozanimod Following Intracerebral Hemorrhage in Mice. Frontiers in molecular neuroscience\| PubMed ID: 35782389	2022
Minocycline treatment in clinically isolated syndrome and serum NfL, GFAP, and metalloproteinase levels. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 35848622	2022
Microglia in multiple sclerosis: Protectors turn destroyers. Neuron\| PubMed ID: 35882229	2022
Expression of antioxidant enzymes in lesions of multiple sclerosis and its models. Scientific reports\| PubMed ID: 35882921	2022
Neuroprotective Effects of Chlorogenic Acid in a Mouse Model of Intracerebral Hemorrhage Associated with Reduced Extracellular Matrix Metalloproteinase Inducer. Biomolecules\| PubMed ID: 35892330	2022
Microglia-T cell conversations in brain cancer progression. Trends in molecular medicine\| PubMed ID: 36075812	2022
Extracellular matrix metalloproteinase inducer in brain ischemia and intracerebral hemorrhage. Frontiers in immunology\| PubMed ID: 36119117	2022
Aging microglia: old friends greet new enemies. Aging\| PubMed ID: 36173626	2022
Detecting monocyte trafficking in an animal model of glioblastoma using R* and quantitative susceptibility mapping. Cancer immunology, immunotherapy : CII\| PubMed ID: 36194288	2023
Bladder dysfunction in experimental autoimmune encephalomyelitis reflects clinical severity: A pilot study. Journal of neuroimmunology\| PubMed ID: 36209613	2022
Serum neurofilament-light and glial fibrillary acidic protein levels in hydroxychloroquine-treated primary progressive multiple sclerosis. European journal of neurology\| PubMed ID: 36214614	2023
Therapeutic strategies for intracerebral hemorrhage. Frontiers in neurology\| PubMed ID: 36408517	2022
Multiple sclerosis progression: time for a new mechanism-driven framework. The Lancet. Neurology\| PubMed ID: 36410373	2023
The Important Role of Zinc in Neurological Diseases. Biomolecules\| PubMed ID: 36671413	2022
Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor-Initiating Cells. Cancer research\| PubMed ID: 37067922	2023
The Promise of Niacin in Neurology. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 37084148	2023
Single-cell and spatial RNA sequencing identify perturbators of microglial functions with aging. Nature aging\| PubMed ID: 37118444	2022
Single Cell Analysis of High-Parameter Histology Images Using Histoflow Cytometry. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 37133337	2023
Enhanced liver X receptor signalling reduces brain injury and promotes tissue regeneration following experimental intracerebral haemorrhage: roles of microglia/macrophages. Stroke and vascular neurology\| PubMed ID: 37137522	2023
Elevated Galectin-3 Is Associated with Aging, Multiple Sclerosis, and Oxidized Phosphatidylcholine-Induced Neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 37208177	2023
Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice. Journal of inflammation research\| PubMed ID: 37342770	2023
Iron in multiple sclerosis - Neuropathology, immunology, and real-world considerations. Multiple sclerosis and related disorders\| PubMed ID: 37579645	2023
Distinct characteristics and severity of brain magnetic resonance imaging lesions in women and men with multiple sclerosis assessed using verified texture analysis measures. Frontiers in neurology\| PubMed ID: 37638198	2023
Omarigliptin inhibits brain cell ferroptosis after intracerebral hemorrhage. Scientific reports\| PubMed ID: 37658227	2023
The extracellular matrix as modifier of neuroinflammation and recovery in ischemic stroke and intracerebral hemorrhage. Neurobiology of disease\| PubMed ID: 37683956	2023
Ion Channel Dysregulation Following Intracerebral Hemorrhage. Neuroscience bulletin\| PubMed ID: 37755675	2024
Tolerability of subcutaneous ofatumumab with long-term exposure in relapsing multiple sclerosis. Multiple sclerosis journal - experimental, translational and clinical\| PubMed ID: 37829441	2023
Anti-oxidant effects of cannabidiol relevant to intracerebral hemorrhage. Frontiers in pharmacology\| PubMed ID: 37841923	2023
Early life stress aggravates disease pathogenesis in mice with experimental autoimmune encephalomyelitis: Support for a two-hit hypothesis of multiple sclerosis etiology. Journal of neuroimmunology\| PubMed ID: 37951203	2023
Prominent elevation of extracellular matrix molecules in intracerebral hemorrhage. Frontiers in molecular neuroscience\| PubMed ID: 38025264	2023
Crosstalk Between Matrix Metalloproteinases and Their Inducer EMMPRIN/CD147: a Promising Therapeutic Target for Intracerebral Hemorrhage. Translational stroke research\| PubMed ID: 38100014	2023
Towards improving the prognosis of stroke through targeting the circadian clock system. International journal of biological sciences\| PubMed ID: 38169640	2024
Uncovering Novel Extracellular Matrix Transcriptome Alterations in Lesions of Multiple Sclerosis. International journal of molecular sciences\| PubMed ID: 38279239	2024
Feasibility study to assess lesion repair in relapsing-remitting multiple sclerosis: A randomized controlled pilot clinical trial of domperidone add-on treatment. Multiple sclerosis and related disorders\| PubMed ID: 38461731	2024
Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice. International immunopharmacology\| PubMed ID: 38565042	2024
Biology of neurofibrosis with focus on multiple sclerosis. Frontiers in immunology\| PubMed ID: 38596673	2024
Genetically predicted hypotaurine levels mediate the relationship between immune cells and intracerebral hemorrhage. International immunopharmacology\| PubMed ID: 38608476	2024
LXR agonism for CNS diseases: promises and challenges. Journal of neuroinflammation\| PubMed ID: 38627787	2024
The cerebroprotection and prospects of FNDC5/irisin in stroke. Neuropharmacology\| PubMed ID: 38705569	2024
From progression to progress: The future of multiple sclerosis. Journal of central nervous system disease\| PubMed ID: 38711957	2024
Fibulin-2 is an extracellular matrix inhibitor of oligodendrocytes relevant to multiple sclerosis. The Journal of clinical investigation\| PubMed ID: 38743490	2024