Reinhard Gruber

Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern

Affiliated withSchool of Dental Medicine, University of Bern

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 12	2015

Other Publications

Article	Year
Platelet-released supernatants stimulate formation of osteoclast-like cells through a prostaglandin/RANKL-dependent mechanism. Bone\| PubMed ID: 11996911	2002
Platelets stimulate proliferation of bone cells: involvement of platelet-derived growth factor, microparticles and membranes. Clinical oral implants research\| PubMed ID: 12453131	2002
The stable analog carbocyclic TXA2 but not platelet-released TXA2 induces osteoclast-like cell formation. Prostaglandins, leukotrienes, and essential fatty acids\| PubMed ID: 12628222	2003
Sinus grafting with autogenous platelet-rich plasma and bovine hydroxyapatite. A histomorphometric study in minipigs. Clinical oral implants research\| PubMed ID: 12869013	2003
Platelets are mitogenic for periosteum-derived cells. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 12919885	2003
BMP-6-induced osteogenic differentiation of mesenchymal cell lines is not modulated by sex steroids and resveratrol. Cytokine\| PubMed ID: 12967649	2003
Enhanced bone-to-implant contact by platelet-released growth factors in mandibular cortical bone: a histomorphometric study in minipigs. The International journal of oral & maxillofacial implants\| PubMed ID: 14579956	2003
Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions. Platelets\| PubMed ID: 14985174	2004
Effects of fibrin sealant protein concentrate with and without platelet-released growth factors on bony healing of cortical mandibular defects. An experimental study in minipigs. Clinical oral implants research\| PubMed ID: 15142092	2004
Effect of platelet-released growth factors and collagen type I on osseous regeneration of mandibular defects. A pilot study in minipigs. Journal of clinical periodontology\| PubMed ID: 15312102	2004
Porcine sinus mucosa holds cells that respond to bone morphogenetic protein (BMP)-6 and BMP-7 with increased osteogenic differentiation in vitro. Clinical oral implants research\| PubMed ID: 15355400	2004
Platelet-released supernatant increases matrix metalloproteinase-2 production, migration, proliferation, and tube formation of human umbilical vascular endothelial cells. Journal of periodontology\| PubMed ID: 15515342	2004
Bone formation following sinus grafting with autogenous bone-derived cells and bovine bone mineral in minipigs: preliminary findings. Clinical oral implants research\| PubMed ID: 15533135	2004
Proliferation and osteogenic differentiation of cells from cortical bone cylinders, bone particles from mill, and drilling dust. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons\| PubMed ID: 15690294	2005
Platelets can neutralize hydrogen peroxide in an acute toxicity model with cells involved in granulation tissue formation. Bone\| PubMed ID: 15784190	2005
Bone marrow stromal cells can provide a local environment that favors migration and formation of tubular structures of endothelial cells. Tissue engineering\| PubMed ID: 15998229	2005
Cathepsin K levels in the crevicular fluid of dental implants: a pilot study. Journal of clinical periodontology\| PubMed ID: 16553640	2006
Bone marrow stromal cells of young and adult rats respond similarly to platelet-released supernatant and bone morphogenetic protein-6 in vitro. Journal of periodontology\| PubMed ID: 16584353	2006
Osteogenic differentiation induced by bone morphogenetic proteins can be suppressed by platelet-released supernatant in vitro. Clinical oral implants research\| PubMed ID: 16584415	2006
Soluble RANKL in crevicular fluid of dental implants: a pilot study. Clinical implant dentistry and related research\| PubMed ID: 16919021	2006
Age-related changes of cell outgrowth from rat calvarial and mandibular bone in vitro. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery\| PubMed ID: 17055735	2006
Activated platelets retain their potential to induce osteoclast-like cell formation in murine bone marrow cultures. Platelets\| PubMed ID: 17074724	2006
Radiological and clinical follow-up of machined- and anodized-surface implants after mean functional loading for 33 months. Clinical oral implants research\| PubMed ID: 17092223	2006
Fracture healing in the elderly patient. Experimental gerontology\| PubMed ID: 17092679	2006
Plasminogen activation by fibroblasts from periodontal ligament and gingiva is not directly affected by chemokines in vitro. Archives of oral biology\| PubMed ID: 17296163	2007
The anti-angiogenic substance TNP-470 impairs peri-implant bone formation: a pilot study in the rabbit metaphysis model. Clinical oral implants research\| PubMed ID: 17298491	2007
Activated platelets positively regulate RANKL-mediated osteoclast differentiation. Journal of cellular biochemistry\| PubMed ID: 17957725	2007
Simultaneous in vivo comparison of bone substitutes in a guided bone regeneration model. Biomaterials\| PubMed ID: 18455786	2008
Osseointegration of a subperiosteal anchoring device in the minipig mandible. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics\| PubMed ID: 18456149	2008
Bone cell responsiveness to growth and differentiation factors under hypoxia in vitro. The International journal of oral & maxillofacial implants\| PubMed ID: 18700363	2008
[Bisphosphonate-associated osteonecrosis of the jaw]. Wiener klinische Wochenschrift\| PubMed ID: 18820850	2008
Activated platelets increase fibrinolysis of mesenchymal progenitor cells. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 19030175	2009
Are culture-expanded autogenous bone cells a clinically reliable option for sinus grafting? Clinical oral implants research\| PubMed ID: 19077153	2009
Long-term effects of magnetron-sputtered calcium phosphate coating on osseointegration of dental implants in non-human primates. Clinical oral implants research\| PubMed ID: 19191794	2009
Age-related efficacy of parathyroid hormone on osseointegration in the rat. Clinical oral implants research\| PubMed ID: 19298294	2009
Sinus augmentation analysis revised: the gradient of graft consolidation. Clinical oral implants research\| PubMed ID: 19519790	2009
Development of an in vitro model on cellular adhesion on granular natural bone mineral under dynamic seeding conditions--a pilot study. Journal of biomedical materials research. Part B, Applied biomaterials\| PubMed ID: 19582840	2009
Paste-like inorganic bone matrix: preclinical testing of a prototype preparation in the porcine calvaria. Clinical oral implants research\| PubMed ID: 19681965	2009
Neutrophil elastase activity and concentrations of interleukin 1-beta in crevicular fluid after immediate replacement and immediate loading of implants. The British journal of oral & maxillofacial surgery\| PubMed ID: 19913336	2010
Collagen barrier membranes decrease osteoclastogenesis in murine bone marrow cultures. Clinical oral implants research\| PubMed ID: 20337667	2010
Review of dental implant rat research models simulating osteoporosis or diabetes. The International journal of oral & maxillofacial implants\| PubMed ID: 20556250	2010
Effects of carboxymethylcellulose and hydroxypropylmethylcellulose on the differentiation and activity of osteoclasts and osteoblasts. Journal of biomedical materials research. Part A\| PubMed ID: 20665677	2010
Cell biology of osteoimmunology. Wiener medizinische Wochenschrift (1946)\| PubMed ID: 20714814	2010
Mechanisms involved in the inhibition of osteoclast generation by the benzothiophene SERM LY117018. Wiener klinische Wochenschrift\| PubMed ID: 20938747	2010
Cortical porosity of the mandible in an osteoporotic sheep model. Clinical oral implants research\| PubMed ID: 21087316	2011
The impact of ovariectomy and hyperglycemia on graft consolidation in rat calvaria. Clinical oral implants research\| PubMed ID: 21244496	2011
Intermittent parathyroid hormone fails to stimulate osseointegration in diabetic rats. Clinical oral implants research\| PubMed ID: 21251075	2011
The effect of BMP-2 on the osteoconductive properties of β-tricalcium phosphate in rat calvaria defects. Biomaterials\| PubMed ID: 21376389	2011
Resorption of deproteinized bovine bone mineral in a porcine calvaria augmentation model. Clinical oral implants research\| PubMed ID: 21554404	2012
The impact of Er,Cr:YSGG laser on the shear strength of the bond between dentin and ceramic is dependent on the adhesive material. Lasers in medical science\| PubMed ID: 21773765	2012
Peri-implantitis and late implant failures in postmenopausal women: a cross-sectional study. Journal of clinical periodontology\| PubMed ID: 21777269	2011
Impact of dietary vitamin D on osseointegration in the ovariectomized rat. Clinical oral implants research\| PubMed ID: 22151621	2012
Impact of bone harvesting techniques on cell viability and the release of growth factors of autografts. Clinical implant dentistry and related research\| PubMed ID: 22375920	2013
Bone healing around titanium implants in two rat colitis models. Clinical oral implants research\| PubMed ID: 22509782	2013
Resonance frequency analysis: a new diagnostic tool for dental ankylosis. European journal of oral sciences\| PubMed ID: 22607343	2012
Osteocyte lacunar density and area in newly formed bone of the augmented sinus. Clinical oral implants research\| PubMed ID: 22784394	2013
Reader's digest of the pathophysiology of bone metastases. Wiener medizinische Wochenschrift (1946)\| PubMed ID: 22797871	2012
Prolyl hydroxylase inhibitors increase the production of vascular endothelial growth factor in dental pulp-derived cells. Journal of endodontics\| PubMed ID: 23063224	2012
Acid and alkali etching of grit blasted zirconia: Impact on adhesion and osteogenic differentiation of MG63 cells in vitro. Dental materials journal\| PubMed ID: 23207221	2012
In vitro evaluation of demineralized freeze-dried bone allograft in combination with enamel matrix derivative. Journal of periodontology\| PubMed ID: 23347347	2013
Immediate shear bond strengths of a composite, a compomer and a glass ionomer to a ceramic substrate. The journal of adhesive dentistry\| PubMed ID: 23534021	2013
Acid and alkaline etching of sandblasted zirconia implants: a histomorphometric study in miniature pigs. Clinical implant dentistry and related research\| PubMed ID: 23574426	2014
In vitro characterization of a synthetic calcium phosphate bone graft on periodontal ligament cell and osteoblast behavior and its combination with an enamel matrix derivative. Clinical oral investigations\| PubMed ID: 23620149	2014
Platelets increase while serum reduces the differentiation and activity of osteoclasts in vitro. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 23703957	2013
L-mimosine and dimethyloxaloylglycine decrease plasminogen activation in periodontal fibroblasts. Journal of periodontology\| PubMed ID: 23826644	2014
Enamel matrix derivative inhibits adipocyte differentiation of 3T3-L1 cells via activation of TGF-βRI kinase activity. PloS one\| PubMed ID: 23951076	2013
Early bone apposition to hydrophilic and hydrophobic titanium implant surfaces: a histologic and histomorphometric study in minipigs. Clinical oral implants research\| PubMed ID: 24118429	2014
TGF-βRI kinase activity mediates Emdogain-stimulated in vitro osteoclastogenesis. Clinical oral investigations\| PubMed ID: 24221580	2014
In vitro adhesion of fibroblastic cells to titanium alloy discs treated with sodium hydroxide. Clinical oral implants research\| PubMed ID: 24372935	2015
Bone-Conditioned Medium Inhibits Osteogenic and Adipogenic Differentiation of Mesenchymal Cells In Vitro. Clinical implant dentistry and related research\| PubMed ID: 24461197	2014
Impact of bone graft harvesting techniques on bone formation and graft resorption: a histomorphometric study in the mandibles of minipigs. Clinical oral implants research\| PubMed ID: 24547966	2015
Soft tissue wound healing around teeth and dental implants. Journal of clinical periodontology\| PubMed ID: 24641001	2014
Osteoclast-like cells on deproteinized bovine bone mineral and biphasic calcium phosphate: light and transmission electron microscopical observations. Clinical oral implants research\| PubMed ID: 24665833	2015
Dental and periodontal phenotype in sclerostin knockout mice. International journal of oral science\| PubMed ID: 24699186	2014
Clinical study on survival rate of short implants placed in the posterior mandibular region: resonance frequency analysis. Clinical oral implants research\| PubMed ID: 24735480	2014
Removal of fractured endodontic instruments using an Nd:YAG laser. Quintessence international (Berlin, Germany : 1985)\| PubMed ID: 24847495	2014
Migration background is associated with caries in Viennese school children, even if parents have received a higher education. BMC oral health\| PubMed ID: 24886105	2014
Human bone chips release of sclerostin and FGF-23 into the culture medium: an in vitro pilot study. Clinical oral implants research\| PubMed ID: 24888411	2014
In vitro release of dimethyloxaloylglycine and l-mimosine from bovine bone mineral. Archives of oral biology\| PubMed ID: 24960117	2014
Long-term stability of contour augmentation in the esthetic zone: histologic and histomorphometric evaluation of 12 human biopsies 14 to 80 months after augmentation. Journal of periodontology\| PubMed ID: 25008214	2014
Sterile-filtered saliva is a strong inducer of IL-6 and IL-8 in oral fibroblasts. Clinical oral investigations\| PubMed ID: 25115993	2015
Dimethyloxalylglycine lyophilized onto bone substitutes increase vessel area in rat calvarial defects. Clinical oral implants research\| PubMed ID: 25196581	2015
Emdogain-regulated gene expression in palatal fibroblasts requires TGF-βRI kinase signaling. PloS one\| PubMed ID: 25197981	2014
Proteomic analysis of porcine bone-conditioned medium. The International journal of oral & maxillofacial implants\| PubMed ID: 25216150	2014
Molecular and cellular basis of bone resorption. Wiener medizinische Wochenschrift (1946)\| PubMed ID: 25223736	2015
Long-term storage affects adhesion between titanium and zirconia using resin cements. The journal of adhesive dentistry\| PubMed ID: 25264548	2014
Bone substitute materials supplemented with prolyl hydroxylase inhibitors decrease osteoclastogenesis in vitro. Journal of biomedical materials research. Part B, Applied biomaterials\| PubMed ID: 25312707	2014
Alveolar bone regeneration in response to local application of calcitriol in vitamin D deficient rats. Journal of clinical periodontology\| PubMed ID: 25469560	2015
Conditioned medium from fresh and demineralized bone enhances osteoclastogenesis in murine bone marrow cultures. Clinical oral implants research\| PubMed ID: 25754222	2015
The in vitro impact of toothpaste extracts on cell viability. European journal of oral sciences\| PubMed ID: 25782087	2015
Conditioned medium of demineralized freeze-dried bone activates gene expression in periodontal fibroblasts in vitro. Journal of periodontology\| PubMed ID: 25786563	2015
Immediate implant placement with simultaneous guided bone regeneration in the esthetic zone: 10-year clinical and radiographic outcomes. Clinical oral implants research\| PubMed ID: 25906924	2015
Salivary Pellicle vs Whole Saliva: The Response of Oral Fibroblasts Based on a Genome-Wide Microarray. The International journal of oral & maxillofacial implants\| PubMed ID: 26009907	2015
The Effect of Parathyroid Hormone on Osseointegration in Insulin-Treated Diabetic Rats. Implant dentistry\| PubMed ID: 26126148	2015