Jan Marik

Biomedical Imaging, Genentech, Inc

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2015

Other Publications

Article	Year
A novel peptide-based encoding system for "one-bead one-compound" peptidomimetic and small molecule combinatorial libraries. Journal of the American Chemical Society\| PubMed ID: 12083920	2002
Synthesis of hydrophilic and flexible linkers for peptide derivatization in solid phase. Bioorganic & medicinal chemistry letters\| PubMed ID: 14684320	2004
Design, synthesis, screening, and decoding of encoded one-bead one-compound peptidomimetic and small molecule combinatorial libraries. Methods in enzymology\| PubMed ID: 14722959	2003
Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15128836	2004
Novel peptide ligands for integrin alpha 4 beta 1 overexpressed in cancer cells. Molecular cancer therapeutics\| PubMed ID: 15486200	2004
Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15845458	2005
Identification of novel targeting peptides for human ovarian cancer cells using "one-bead one-compound" combinatorial libraries. Molecular cancer therapeutics\| PubMed ID: 15897245	2005
Near-infrared optical imaging of ovarian cancer xenografts with novel alpha 3-integrin binding peptide "OA02". Molecular imaging\| PubMed ID: 16285906	2005
Peptide and small-molecule microarrays. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 16353378	2005
Peptide ligands targeting integrin alpha3beta1 in non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 16635537	2006
Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging. Nature chemical biology\| PubMed ID: 16767086	2006
Solid-phase synthesis of 2-[18F]fluoropropionyl peptides. Bioconjugate chemistry\| PubMed ID: 16848410	2006
Fully automated preparation of n.c.a. 4-[18F]fluorobenzoic acid and N-succinimidyl 4-[18F]fluorobenzoate using a Siemens/CTI chemistry process control unit (CPCU). Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine\| PubMed ID: 16935516	2007
The minimum element of a synthetic peptide required to block prostate tumor cell migration. Cancer biology & therapy\| PubMed ID: 17102593	2006
Long-circulating liposomes radiolabeled with [18F]fluorodipalmitin ([18F]FDP). Nuclear medicine and biology\| PubMed ID: 17307124	2007
Use of a peptide derived from foot-and-mouth disease virus for the noninvasive imaging of human cancer: generation and evaluation of 4-[18F]fluorobenzoyl A20FMDV2 for in vivo imaging of inte... Cancer research\| PubMed ID: 17699789	2007
From combinatorial chemistry to cancer-targeting peptides. Molecular pharmaceutics\| PubMed ID: 17880166	2007
Evaluation of ketone-oxime method for developing therapeutic on-demand cleavable immunoconjugates. Bioconjugate chemistry\| PubMed ID: 18494516	2008
Dynamic microPET imaging of ultrasound contrast agents and lipid delivery. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 18718854	2008
In vivo positron emission tomography (PET) imaging with an alphavbeta6 specific peptide radiolabeled using 18F-"click" chemistry: evaluation and comparison with the corresponding 4-[18F]fluo... Journal of medicinal chemistry\| PubMed ID: 18785727	2008
Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method. Journal of medicinal chemistry\| PubMed ID: 19055415	2009
PET of glial metabolism using 2-18F-fluoroacetate. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 19443600	2009
Targeted in vivo imaging of integrin alphavbeta6 with an improved radiotracer and its relevance in a pancreatic tumor model. Cancer research\| PubMed ID: 19549907	2009
A modular platform for the rapid site-specific radiolabeling of proteins with 18F exemplified by quantitative positron emission tomography of human epidermal growth factor receptor 2. Journal of medicinal chemistry\| PubMed ID: 19736996	2009
High-throughput in vivo screening of targeted molecular imaging agents. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19815497	2009
Site-specifically 89Zr-labeled monoclonal antibodies for ImmunoPET. Nuclear medicine and biology\| PubMed ID: 20346868	2010
Development and evaluation of a novel method for preclinical measurement of tissue vascular volume. Molecular pharmaceutics\| PubMed ID: 20704296	2010
Emerging role of immunoPET in receptor targeted cancer therapy. Current drug delivery\| PubMed ID: 21034420	2011
The development of peptide-based tools for the analysis of angiogenesis. Chemistry & biology\| PubMed ID: 21802005	2011
Preparation of 18F-labeled peptides using the copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition. Nature protocols\| PubMed ID: 22011654	2011
Immuno-PET of the hepatocyte growth factor receptor Met using the 1-armed antibody onartuzumab. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 22917884	2012
ImmunoPET imaging of phosphatidylserine in pro-apoptotic therapy treated tumor models. Nuclear medicine and biology\| PubMed ID: 23062948	2013
Enhanced tumor retention of a radiohalogen label for site-specific modification of antibodies. Journal of medicinal chemistry\| PubMed ID: 24131491	2013
Evaluation of 2-[¹⁸F]fluoroacetate kinetics in rodent models of cerebral hypoxia-ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 24517980	2014
New imaging paradigms in drug development: the PET imaging approach. Drug discovery today. Technologies\| PubMed ID: 24990264	2011