Journal
/
Medicine
/
Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia

Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia

DOI:
10.3791/52728-v

•

10:35 min

•

September 20, 2015

•

, , , , ,
1Department of Biomedical Engineering,University of California, Davis, 2Nuclear Magnetic Resonance Facility,University of California, Davis, 3Biomedical Imaging,Genentech, Inc, 4Department of Radiology,University of California, Davis

Chapters

  • 00:05Title
  • 01:16Unilateral Common Carotid Artery Ligation
  • 03:48Imaging Preparation
  • 06:20MRI Imaging
  • 09:06Results: Multimodal Imaging of Ischemic Insults
  • 10:11Conclusion

Summary

Automatic Translation

Automatic Translation

The method presented here uses simultaneous positron emission tomography and magnetic resonance imaging. In the cerebral hypoxia-ischemia model, dynamic changes in diffusion and glucose metabolism occur during and after injury. The evolving and irreproducible damage in this model necessitates simultaneous acquisition if meaningful multi-modal imaging data are to be acquired.

Tags

Keywords: PET/MRI ImagingCerebral Hypoxia-ischemiaDiffusion Weighted MRIGlucose Metabolism[18F]FDG PETBioenergetics DisturbanceVascular DifferencesSimultaneous Data Acquisition

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/52728?article_type=v

Mouse Model of Middle Cerebral Artery Occlusion
check_url/52728?article_type=v

The Application Of Permanent Middle Cerebral Artery Ligation in the Mouse
check_url/52728?article_type=v

Mouse Model of Intraluminal MCAO: Cerebral Infarct Evaluation by Cresyl Violet Staining
check_url/52728?article_type=v

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
check_url/52728?article_type=v

Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion
check_url/52728?article_type=v

In Vivo Dynamics of Retinal Microglial Activation During Neurodegeneration: Confocal Ophthalmoscopic Imaging and Cell Morphometry in Mouse Glaucoma
check_url/52728?article_type=v

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
check_url/52728?article_type=v

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
check_url/52728?article_type=v

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
check_url/52728?article_type=v

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Read Article