Alexander Staruschenko

Departments of Physiology, Medical College of Wisconsin

Affiliated withMedical College of Wisconsin

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 4	Year
Publication title Cited by 5	2015
Publication title Cited by 25	2015
Publication title Cited by 15	2015
Publication title Cited by 12	2015

Other Publications

Article	Year
Fluorescence resonance energy transfer analysis of subunit stoichiometry of the epithelial Na+ channel. The Journal of biological chemistry\| PubMed ID: 15096495	2004
Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling. The Journal of biological chemistry\| PubMed ID: 15215250	2004
Rho small GTPases activate the epithelial Na(+) channel. The Journal of biological chemistry\| PubMed ID: 15448132	2004
Epithelial Na+ channel subunit stoichiometry. Biophysical journal\| PubMed ID: 15821171	2005
Actin cytoskeleton disassembly affects conductive properties of stretch-activated cation channels in leukaemia cells. Biochimica et biophysica acta\| PubMed ID: 15842999	2005
Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channel. Biochimica et biophysica acta\| PubMed ID: 15893513	2005
Identification of a functional phosphatidylinositol 3,4,5-trisphosphate binding site in the epithelial Na+ channel. The Journal of biological chemistry\| PubMed ID: 16154997	2005
Regulation of epithelial Na+ channel activity by conserved serine/threonine switches within sorting signals. The Journal of biological chemistry\| PubMed ID: 16203727	2005
Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides. American journal of physiology. Renal physiology\| PubMed ID: 16601296	2006
Rapid translocation and insertion of the epithelial Na+ channel in response to RhoA signaling. The Journal of biological chemistry\| PubMed ID: 16829523	2006
Magnesium permeation through mechanosensitive channels: single-current measurements. Cell research\| PubMed ID: 16871269	2006
Functional reconstitution of the human epithelial Na+ channel in a mammalian expression system. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 16929934	2006
Binding and direct activation of the epithelial Na+ channel (ENaC) by phosphatidylinositides. The Journal of physiology\| PubMed ID: 17272344	2007
Quantifying RhoA facilitated trafficking of the epithelial Na+ channel toward the plasma membrane with total internal reflection fluorescence-fluorescence recovery after photobleaching. The Journal of biological chemistry\| PubMed ID: 17376773	2007
Acute regulation of the epithelial Na+ channel by phosphatidylinositide 3-OH kinase signaling in native collecting duct principal cells. Journal of the American Society of Nephrology : JASN\| PubMed ID: 17442787	2007
Subunit-dependent cadmium and nickel inhibition of acid-sensing ion channels. Developmental neurobiology\| PubMed ID: 17443775	2007
Molecular determinants of PI(4,5)P2 and PI(3,4,5)P3 regulation of the epithelial Na+ channel. The Journal of general physiology\| PubMed ID: 17893193	2007
Ion channel regulation by Ras, Rho, and Rab small GTPases. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 17959838	2007
Mechanisms of non-steroid anti-inflammatory drugs action on ASICs expressed in hippocampal interneurons. Journal of neurochemistry\| PubMed ID: 18410516	2008
Insight toward epithelial Na+ channel mechanism revealed by the acid-sensing ion channel 1 structure. IUBMB life\| PubMed ID: 18459164	2008
Regulation of ENaC expression at the cell surface by Rab11. Biochemical and biophysical research communications\| PubMed ID: 18926797	2008
Intrinsic voltage dependence of the epithelial Na+ channel is masked by a conserved transmembrane domain tryptophan. The Journal of biological chemistry\| PubMed ID: 19620245	2009
Muscarinic M1 modulation of acid-sensing ion channels. Neuroreport\| PubMed ID: 19730136	2009
Peroxisome proliferator-activated receptor gamma antagonists decrease Na+ transport via the epithelial Na+ channel. Molecular pharmacology\| PubMed ID: 19752200	2009
EGF and its related growth factors mediate sodium transport in mpkCCDc14 cells via ErbB2 (neu/HER-2) receptor. Journal of cellular physiology\| PubMed ID: 20049896	2010
Intact cytoskeleton is required for small G protein dependent activation of the epithelial Na+ channel. PloS one\| PubMed ID: 20098689	2010
Contribution of TRPV1-TRPA1 interaction to the single channel properties of the TRPA1 channel. The Journal of biological chemistry\| PubMed ID: 20231274	2010
Endothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2. Journal of the American Society of Nephrology : JASN\| PubMed ID: 20338996	2010
Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors. PPAR research\| PubMed ID: 20613963	2010
The actin cytoskeleton and small G protein RhoA are not involved in flow-dependent activation of ENaC. BMC research notes\| PubMed ID: 20663206	2010
Epidermal growth factor-mediated proliferation and sodium transport in normal and PKD epithelial cells. Biochimica et biophysica acta\| PubMed ID: 20959142	2011
Novel role of Rac1/WAVE signaling mechanism in regulation of the epithelial Na+ channel. Hypertension\| PubMed ID: 21464391	2011
NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli. Biochemical and biophysical research communications\| PubMed ID: 21473850	2011
Cortical actin binding protein cortactin mediates ENaC activity via Arp2/3 complex. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 21536685	2011
Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC). American journal of physiology. Renal physiology\| PubMed ID: 21697242	2011
Angiotensin II increases activity of the epithelial Na+ channel (ENaC) in distal nephron additively to aldosterone. The Journal of biological chemistry\| PubMed ID: 22086923	2012
Role of βPix in the Kidney. Frontiers in physiology\| PubMed ID: 22654768	2012
ROS production as a common mechanism of ENaC regulation by EGF, insulin, and IGF-1. American journal of physiology. Cell physiology\| PubMed ID: 23135700	2013
Direct activation of ENaC by angiotensin II: recent advances and new insights. Current hypertension reports\| PubMed ID: 23180052	2013
Regulation of transport in the connecting tubule and cortical collecting duct. Comprehensive Physiology\| PubMed ID: 23227301	2012
G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23236168	2012
Recording ion channels in isolated, split-opened tubules. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23529443	2013
Single-channel analysis of TRPC channels in the podocytes of freshly isolated Glomeruli. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23529444	2013
Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23558339	2013
Detection of endogenous substances with enzymatic microelectrode biosensors in the kidney. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 23594609	2013
Real-time electrochemical detection of ATP and H₂O₂ release in freshly isolated kidneys. American journal of physiology. Renal physiology\| PubMed ID: 23594827	2013
Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension. Journal of the American Society of Nephrology : JASN\| PubMed ID: 23599382	2013
Epidermal growth factors in the kidney and relationship to hypertension. American journal of physiology. Renal physiology\| PubMed ID: 23637204	2013
Aldosterone-dependent trans-activation and epigenetic derepression of ENaC: where is the balance? American journal of physiology. Renal physiology\| PubMed ID: 23842778	2013
Orally active epoxyeicosatrienoic acid analog attenuates kidney injury in hypertensive Dahl salt-sensitive rat. Hypertension\| PubMed ID: 23980070	2013
Direct inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamine. American journal of physiology. Renal physiology\| PubMed ID: 23986512	2013
Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells. Cell and tissue research\| PubMed ID: 24036843	2013
Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. American journal of physiology. Cell physiology\| PubMed ID: 24048730	2013
PC and PKC: in vivo vs. in vitro. American journal of physiology. Renal physiology\| PubMed ID: 24370588	2014
Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli. Kidney international\| PubMed ID: 24646854	2014
Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition. Clinical science (London, England : 1979)\| PubMed ID: 24707975	2014
To cleave or not to cleave: role of ADAM17 in cell proliferation in PKD. American journal of physiology. Renal physiology\| PubMed ID: 25056345	2014
Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25136115	2014
Role of Rho GDP dissociation inhibitor α in control of epithelial sodium channel (ENaC)-mediated sodium reabsorption. The Journal of biological chemistry\| PubMed ID: 25164814	2014
Impaired epithelial Na+ channel activity contributes to cystogenesis and development of autosomal recessive polycystic kidney disease in PCK rats. Pediatric research\| PubMed ID: 25279988	2015
Cross-talk between insulin and IGF-1 receptors in the cortical collecting duct principal cells: implication for ENaC-mediated Na+ reabsorption. American journal of physiology. Renal physiology\| PubMed ID: 25651558	2015
Acetylation stimulates the epithelial sodium channel by reducing its ubiquitination and degradation. The Journal of biological chemistry\| PubMed ID: 25787079	2015
Inhibition of ENaC by endothelin-1. Vitamins and hormones\| PubMed ID: 25817869	2015
TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases. American journal of physiology. Renal physiology\| PubMed ID: 26084930	2015
S&R Foundation 15th Anniversary. The Physiologist\| PubMed ID: 26442383	2015