Mark S. Humayun

Biomedical Engineering, University of Southern California

Affiliated withUniversity of Southern California Keck School of Medicine of the University of Southern California

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2015
Publication title Cited by 1	2022

Other Publications

Article	Year
Inferior limited macular translocation for subfoveal choroidal neovascularization secondary to age-related macular degeneration: 1-year visual outcome and recurrence report. American journal of ophthalmology\| PubMed ID: 12095810	2002
Retinal prosthesis for the blind. Survey of ophthalmology\| PubMed ID: 12161210	2002
Ganglion cell responses to retinal light stimulation in the absence of photoreceptor outer segments from retinal degenerate rodents. Current eye research\| PubMed ID: 12187491	2002
Increased spontaneous retinal ganglion cell activity in rd mice after neural retinal transplantation. Investigative ophthalmology & visual science\| PubMed ID: 12202529	2002
Patient selection for macular translocation surgery using the scanning laser ophthalmoscope. Ophthalmology\| PubMed ID: 12208725	2002
A new 25-gauge instrument system for transconjunctival sutureless vitrectomy surgery. Ophthalmology\| PubMed ID: 12359598	2002
Initial experience using the transconjunctival sutureless vitrectomy system for vitreoretinal surgery. Ophthalmology\| PubMed ID: 12359600	2002
Limited macular translocation for the management of subfoveal choroidal neovascularization after photodynamic therapy. American journal of ophthalmology\| PubMed ID: 12504715	2003
Limited macular translocation: current concepts. Ophthalmology clinics of North America\| PubMed ID: 12515074	2002
In vitro electrical properties for iridium oxide versus titanium nitride stimulating electrodes. IEEE transactions on bio-medical engineering\| PubMed ID: 12549739	2002
Improvements after sheathotomy for branch retinal vein occlusion documented by optical coherence tomography and scanning laser ophthalmoscope. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye\| PubMed ID: 12570005	2003
Visual and electrical evoked response recorded from subdural electrodes implanted above the visual cortex in normal dogs under two methods of anesthesia. Journal of neuroscience methods\| PubMed ID: 12606062	2003
Heat effects on the retina. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye\| PubMed ID: 12665226	2003
Angiographic characteristics in patients undergoing macular translocation for subfoveal choroidal neovascularization secondary to age-related macular degeneration. Retina (Philadelphia, Pa.)\| PubMed ID: 12707592	2003
Advances in the development of visual prostheses. Current opinion in ophthalmology\| PubMed ID: 12777929	2003
Visual perception in a blind subject with a chronic microelectronic retinal prosthesis. Vision research\| PubMed ID: 13129543	2003
Facial recognition using simulated prosthetic pixelized vision. Investigative ophthalmology & visual science\| PubMed ID: 14578432	2003
Past, present, and future of artificial vision. Artificial organs\| PubMed ID: 14616514	2003
Visually guided performance of simple tasks using simulated prosthetic vision. Artificial organs\| PubMed ID: 14616520	2003
Characteristics of visual loss by scanning laser ophthalmoscope microperimetry in eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration. American journal of ophthalmology\| PubMed ID: 14644217	2003
The value of preoperative tests in the selection of blind patients for a permanent microelectronic implant. Transactions of the American Ophthalmological Society\| PubMed ID: 14971581	2003
Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: implications for ocular angiogenesis. American journal of ophthalmology\| PubMed ID: 15059706	2004
Effects of intravitreal indocyanine green injection in rabbits. Retina (Philadelphia, Pa.)\| PubMed ID: 15076947	2004
Effects of indocyanine green injection on the retinal surface and into the subretinal space in rabbits. Retina (Philadelphia, Pa.)\| PubMed ID: 15076948	2004
Retinal pigment epithelial abnormalities after internal limiting membrane peeling guided by indocyanine green staining. Retina (Philadelphia, Pa.)\| PubMed ID: 15076960	2004
Virtual vitreoretinal surgical simulator as a training tool. Retina (Philadelphia, Pa.)\| PubMed ID: 15097883	2004
Use of rotational sutures for limited retinal translocation: a new technique for superior limited macular translocation. American journal of ophthalmology\| PubMed ID: 15126156	2004
Comparison of electrical stimulation thresholds in normal and retinal degenerated mouse retina. Japanese journal of ophthalmology\| PubMed ID: 15295659	2004
Macular translocation in patients with recurrent subfoveal choroidal neovascularization after laser photocoagulation for nonsubfoveal choroidal neovascularization. Ophthalmology\| PubMed ID: 15465552	2004
Retinal vein cannulation with prolonged infusion of tissue plasminogen activator (t-PA) for the treatment of experimental retinal vein occlusion in dogs. American journal of ophthalmology\| PubMed ID: 15531319	2004
Retinal thickness in normal and RCD1 dogs using optical coherence tomography. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye\| PubMed ID: 15580972	2004
Laser-induced changes in intraretinal oxygen distribution in pigmented rabbits. Investigative ophthalmology & visual science\| PubMed ID: 15728557	2005
Transvitreal limited arteriovenous-crossing manipulation without vitrectomy for complicated branch retinal vein occlusion using 25-gauge instrumentation. Retina (Philadelphia, Pa.)\| PubMed ID: 15805902	2005
Long-term stimulation by active epiretinal implants in normal and RCD1 dogs. Journal of neural engineering\| PubMed ID: 15876657	2005
Outcomes of 140 consecutive cases of 25-gauge transconjunctival surgery for posterior segment disease. Ophthalmology\| PubMed ID: 15878061	2005
Perceptual thresholds and electrode impedance in three retinal prosthesis subjects. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society\| PubMed ID: 16003900	2005
Retinal prosthesis. Annual review of biomedical engineering\| PubMed ID: 16004575	2005
Rapid recurrence of geographic atrophy after full macular translocation for nonexudative age-related macular degeneration. Ophthalmology\| PubMed ID: 16051364	2005
Implantation of an inactive epiretinal poly(dimethyl siloxane) electrode array in dogs. Experimental eye research\| PubMed ID: 16125701	2006
In vitro and in vivo evaluation of ultrananocrystalline diamond for coating of implantable retinal microchips. Journal of biomedical materials research. Part B, Applied biomaterials\| PubMed ID: 16245292	2006
Old idea, new technology. IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society\| PubMed ID: 16248112	2005
A biomimetic retinal stimulating array. IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society\| PubMed ID: 16248113	2005
Nanobiolistic delivery of indicators to the living mouse retina. Journal of neuroscience methods\| PubMed ID: 16290199	2006
Paragraph text reading using a pixelized prosthetic vision simulator: parameter dependence and task learning in free-viewing conditions. Investigative ophthalmology & visual science\| PubMed ID: 16505065	2006
Retinal prostheses for the blind. Annals of the Academy of Medicine, Singapore\| PubMed ID: 16625261	2006
Electrical stimulation in normal and retinal degeneration (rd1) isolated mouse retina. Vision research\| PubMed ID: 16723150	2006
Enucleated eye model for intraocular retinal prosthesis implantation. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye\| PubMed ID: 16898401	2006
Electrical stimulation in isolated rabbit retina. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society\| PubMed ID: 17009488	2006
Intraocular retinal prosthesis. Big steps to sight restoration. IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society\| PubMed ID: 17020200	2006
A novel method to oxygenate intraocular irrigation fluids with an in-line oxygenator. Retina (Philadelphia, Pa.)\| PubMed ID: 17218920	2007
Effect of oxygenated intraocular irrigation solutions on the electroretinogram after vitrectomy. Retina (Philadelphia, Pa.)\| PubMed ID: 17218921	2007
Intraocular impedance as a function of the position in the eye, electrode material and electrode size. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 17271221	2004
DSP based image processing for retinal prosthesis. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference\| PubMed ID: 17271974	2004
Electrical properties of retinal-electrode interface. Journal of neural engineering\| PubMed ID: 17325413	2007
Visual performance using a retinal prosthesis in three subjects with retinitis pigmentosa. American journal of ophthalmology\| PubMed ID: 17362868	2007
PMN-PT single crystal, high-frequency ultrasonic needle transducers for pulsed-wave Doppler application. IEEE transactions on ultrasonics, ferroelectrics, and frequency control\| PubMed ID: 17375836	2007
Evaluation of a stereoscopic camera-based three-dimensional viewing workstation for ophthalmic surgery. American journal of ophthalmology\| PubMed ID: 17452184	2007
Evaluation of lens hardness in cataract surgery using high-frequency ultrasonic parameters in vitro. Ultrasound in medicine & biology\| PubMed ID: 17618041	2007
Determining the acoustic properties of the lens using a high-frequency ultrasonic needle transducer. Ultrasound in medicine & biology\| PubMed ID: 17673358	2007
Evaluation of ultrasound-assisted thrombolysis using custom liposomes in a model of retinal vein occlusion. Investigative ophthalmology & visual science\| PubMed ID: 22969076	2012
Performance analysis of new-generation vitreous cutters. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie\| PubMed ID: 17876598	2008
A dual band wireless power and data telemetry for retinal prosthesis. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference\| PubMed ID: 17946243	2006
A transcutaneous data telemetry system tolerant to power telemetry interference. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference\| PubMed ID: 17946345	2006
The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits. Investigative ophthalmology & visual science\| PubMed ID: 18055823	2007
Intravitreal and subretinal injection of tissue plasminogen activator (tPA) in the treatment of experimentally created retinal vein occlusion in rabbits. Retina (Philadelphia, Pa.)\| PubMed ID: 18301042	2008
Factors affecting perceptual thresholds in epiretinal prostheses. Investigative ophthalmology & visual science\| PubMed ID: 18515576	2008
The efficacy of retrobulbar block anesthesia only in pars plana vitrectomy and transconjunctival sutureless vitrectomy. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye\| PubMed ID: 18556938	2008
A refillable microfabricated drug delivery device for treatment of ocular diseases. Lab on a chip\| PubMed ID: 18584074	2008
Natural course of experimental retinal vein occlusion in rabbit; arterial occlusion following venous photothrombosis. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie\| PubMed ID: 18642023	2008
An in vitro model of a retinal prosthesis. IEEE transactions on bio-medical engineering\| PubMed ID: 18714839	2008
Predicting visual sensitivity in retinal prosthesis patients. Investigative ophthalmology & visual science\| PubMed ID: 19098313	2009
Immunocytochemical analysis of retinal neurons under electrical stimulation. Brain research\| PubMed ID: 19103179	2009
Metabolic prosthesis for oxygenation of ischemic tissue. IEEE transactions on bio-medical engineering\| PubMed ID: 19304479	2009
Feasibility study of a retinal prosthesis: spatial vision with a 16-electrode implant. Archives of ophthalmology\| PubMed ID: 19365014	2009
A passive MEMS drug delivery pump for treatment of ocular diseases. Biomedical microdevices\| PubMed ID: 19396548	2009
Feasibility of rotational scan ultrasound imaging by an angled high frequency transducer for the posterior segment of the eye. IEEE transactions on ultrasonics, ferroelectrics, and frequency control\| PubMed ID: 19411226	2009
Selective labeling of retinal ganglion cells with calcium indicators by retrograde loading in vitro. Journal of neuroscience methods\| PubMed ID: 19428523	2009
Toward a wide-field retinal prosthesis. Journal of neural engineering\| PubMed ID: 19458405	2009
Brightness as a function of current amplitude in human retinal electrical stimulation. Investigative ophthalmology & visual science\| PubMed ID: 19608533	2009
Effect of multiple injections of small divided doses vs single injection of intravitreal bevacizumab on retinal neovascular model in rabbits. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie\| PubMed ID: 19644699	2010
Artificial vision: needs, functioning, and testing of a retinal electronic prosthesis. Progress in brain research\| PubMed ID: 19660665	2009
Measurements of attenuation coefficient for evaluating the hardness of a cataract lens by a high-frequency ultrasonic needle transducer. Physics in medicine and biology\| PubMed ID: 19759408	2009
A comparison of retinal prosthesis electrode array substrate materials. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference\| PubMed ID: 19963811	2009
Preliminary 6 month results from the Argus II epiretinal prosthesis feasibility study. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 19963839	2009
Biomimetic image processing for retinal prostheses: peripheral saliency cues. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference\| PubMed ID: 19963840	2009
Mini drug pump for ophthalmic use. Transactions of the American Ophthalmological Society\| PubMed ID: 20126483	2009
Mini drug pump for ophthalmic use. Current eye research\| PubMed ID: 20373877	2010
A new dual port cutter system for vitrectomy surgery. Retina (Philadelphia, Pa.)\| PubMed ID: 20924265	2010
Modeling and percept of transcorneal electrical stimulation in humans. IEEE transactions on bio-medical engineering\| PubMed ID: 20952323	2011
Vitreal oxygenation in retinal ischemia reperfusion. Investigative ophthalmology & visual science\| PubMed ID: 21051734	2011
Morphometric analysis of optic nerves and retina from an end-stage retinitis pigmentosa patient with an implanted active epiretinal array. Investigative ophthalmology & visual science\| PubMed ID: 21296811	2011
Both electrical stimulation thresholds and SMI-32-immunoreactive retinal ganglion cell density correlate with age in S334ter line 3 rat retina. Journal of neurophysiology\| PubMed ID: 21411561	2011
Resolution of the epiretinal prosthesis is not limited by electrode size. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society\| PubMed ID: 21511569	2011
Hyperspectral computed tomographic imaging spectroscopy of vascular oxygen gradients in the rabbit retina in vivo. PloS one\| PubMed ID: 21931729	2011
Impedance as a method to sense proximity at the electrode-retina interface. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society\| PubMed ID: 21984523	2011
Retinal prostheses: current clinical results and future needs. Ophthalmology\| PubMed ID: 22047893	2011
Frequency and amplitude modulation have different effects on the percepts elicited by retinal stimulation. Investigative ophthalmology & visual science\| PubMed ID: 22110084	2012
Interim results from the international trial of Second Sight's visual prosthesis. Ophthalmology\| PubMed ID: 22244176	2012
Assessment of MRI issues for the Argus II retinal prosthesis. Magnetic resonance imaging\| PubMed ID: 22260934	2012
Mesh-supported submicron parylene-C membranes for culturing retinal pigment epithelial cells. Biomedical microdevices\| PubMed ID: 22391881	2012
Fluorescein angiography, optical coherence tomography, and histopathologic findings in a VEGF(165) animal model of retinal angiogenesis. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie\| PubMed ID: 22427240	2012
Preservation of retinotopic map in retinal degeneration. Experimental eye research\| PubMed ID: 22685713	2012
A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic research\| PubMed ID: 22868580	2012
Fluidics in a dual pneumatic ultra high-speed vitreous cutter system. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde\| PubMed ID: 23108417	2013
Acute variations in retinal vascular oxygen content in a rabbit model of retinal venous occlusion. PloS one\| PubMed ID: 23185567	2012
Imaging the response of the retina to electrical stimulation with genetically encoded calcium indicators. Journal of neurophysiology\| PubMed ID: 23343890	2013
High-resolution OCT: an innovative tool for posterior segment imaging. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye\| PubMed ID: 23357319	2012
Quantitative analysis of retinal structures using spectral domain optical coherence tomography in normal rabbits. Current eye research\| PubMed ID: 23373715	2013
Performance analysis of ultrahigh-speed vitreous cutter system. Retina (Philadelphia, Pa.)\| PubMed ID: 23416511	2013
Analysis of a 23-gauge ultra high-speed cutter with duty cycle control. Retina (Philadelphia, Pa.)\| PubMed ID: 23416512	2013
Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer. Investigative ophthalmology & visual science\| PubMed ID: 23833067	2013
Elastic properties of human posterior eye. Journal of biomedical materials research. Part A\| PubMed ID: 23852923	2014
A system verification platform for high-density epiretinal prostheses. IEEE transactions on biomedical circuits and systems\| PubMed ID: 23853332	2013
In vivo detection of hESC-RPE cells via confocal near-infrared fundus reflectance. Ophthalmic surgery, lasers & imaging retina\| PubMed ID: 23883533	2013
A fully intraocular high-density self-calibrating epiretinal prosthesis. IEEE transactions on biomedical circuits and systems\| PubMed ID: 24473540	2013
Interphase gap as a means to reduce electrical stimulation thresholds for epiretinal prostheses. Journal of neural engineering\| PubMed ID: 24654269	2014
Retinal prosthesis. IEEE transactions on bio-medical engineering\| PubMed ID: 24710817	2014
Noninvasive assessment of retinal vascular oxygen content among normal and diabetic human subjects: a study using hyperspectral computed tomographic imaging spectroscopy. Retina (Philadelphia, Pa.)\| PubMed ID: 24732694	2014
Microdevice-based cell therapy for age-related macular degeneration. Developments in ophthalmology\| PubMed ID: 24732769	2014
Profile of ocriplasmin and its potential in the treatment of vitreomacular adhesion. Clinical ophthalmology (Auckland, N.Z.)\| PubMed ID: 24851038	2014
Comparison of reaction response time between hand and foot controlled devices in simulated microsurgical testing. BioMed research international\| PubMed ID: 25136619	2014
In vivo Sonothrombolysis of Ear Marginal Vein of Rabbits Monitored with High-frequency Ultrasound Needle Transducer. Journal of medical and biological engineering\| PubMed ID: 25356073	2013
Fluidics comparison between dual pneumatic and spring return high-speed vitrectomy systems. Ophthalmic surgery, lasers & imaging retina\| PubMed ID: 25559512	2015
Stem cell based therapies for age-related macular degeneration: The promises and the challenges. Progress in retinal and eye research\| PubMed ID: 26113213	2015
Ten-Year Follow-up of a Blind Patient Chronically Implanted with Epiretinal Prosthesis Argus I. Ophthalmology\| PubMed ID: 26386850	2015
OPTOMAP WIDEFIELD IMAGING OF THE ARGUS II RETINAL PROSTHESIS IN PATIENTS WITH RETINITIS PIGMENTOSA. Retinal cases & brief reports\| PubMed ID: 26705237	2016
THE SECOND BLIND SPOT: SMALL RETINAL VESSEL VASCULOPATHY AFTER VACCINATION AGAINST NEISSERIA MENINGITIDIS AND YELLOW FEVER. Retinal cases & brief reports\| PubMed ID: 27599107	2017
A Novel Racing Array Transducer for Noninvasive Ultrasonic Retinal Stimulation: A Simulation Study. Sensors (Basel, Switzerland)\| PubMed ID: 30999576	2019
Enhanced Depth Navigation Through Augmented Reality Depth Mapping in Patients with Low Vision. Scientific reports\| PubMed ID: 31375713	2019
Sympathetic Effects of Internal Carotid Nerve Manipulation on Choroidal Vascularity and Related Measures. Investigative ophthalmology & visual science\| PubMed ID: 31618767	2019
Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study. Ophthalmology. Retina\| PubMed ID: 31786135	2020
Subretinal Implantation of a Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium Monolayer in a Porcine Model. Advances in experimental medicine and biology\| PubMed ID: 31884672	2019
Novel probabilistic model of core vitreous traction using microsurgical vitrectomy tools. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie\| PubMed ID: 32809071	2021
Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo. Scientific reports\| PubMed ID: 33737600	2021
Advanced Retina Implants. Ophthalmology. Retina\| PubMed ID: 35436597	2022