Lei Fang

Department of Ophthalmology, University of Basel

Affiliated withUniversity of Basel Medical School of Nanjing University

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 23	2015
Publication title Cited by 2	2020

Other Publications

Article	Year
PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy. Cell research\| PubMed ID: 29934616	2018
Zhonghua wai ke za zhi [Chinese journal of surgery]\| PubMed ID: 23157949	2012
[A fast non-local means algorithm for denoising of computed tomography images]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University\| PubMed ID: 23174586	2012
TNF-α impairs differentiation and function of TGF-β-induced Treg cells in autoimmune diseases through Akt and Smad3 signaling pathway. Journal of molecular cell biology\| PubMed ID: 23243069	2013
Occurrence of glycerol uptake in Dunaliella tertiolecta under hyperosmotic stress. The FEBS journal\| PubMed ID: 23279806	2013
Inactivation of MARCH5 prevents mitochondrial fragmentation and interferes with cell death in a neuronal cell model. PloS one\| PubMed ID: 23285122	2012
Current progresses of novel natural products and their derivatives/ analogs as anti-Alzheimer candidates: an update. Mini reviews in medicinal chemistry\| PubMed ID: 23305400	2013
Propylene glycol-linked amino acid/dipeptide diester prodrugs of oleanolic acid for PepT1-mediated transport: synthesis, intestinal permeability, and pharmacokinetics. Molecular pharmaceutics\| PubMed ID: 23339520	2013
Synthesis of cationic polylactides with tunable charge densities as nanocarriers for effective gene delivery. Molecular pharmaceutics\| PubMed ID: 23339525	2013
Design and synthesis of dimethylaminomethyl-substituted curcumin derivatives/analogues: potent antitumor and antioxidant activity, improved stability and aqueous solubility compared with cur... Bioorganic & medicinal chemistry letters\| PubMed ID: 23357628	2013
Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis. Nature medicine\| PubMed ID: 23396208	2013
Scalable and selective dispersion of semiconducting arc-discharged carbon nanotubes by dithiafulvalene/thiophene copolymers for thin film transistors. ACS nano\| PubMed ID: 23402644	2013
Integrated materials design of organic semiconductors for field-effect transistors. Journal of the American Chemical Society\| PubMed ID: 23557391	2013
Continual production of glycerol from carbon dioxide by Dunaliella tertiolecta. Bioresource technology\| PubMed ID: 23567730	2013
Secondary metabolites from the endophytic fungi Penicillium polonicum and Aspergillus fumigatus. Journal of Asian natural products research\| PubMed ID: 23600807	2013
Meningothelial cells as part of the central nervous system host defense. Biology of the cell / under the auspices of the European Cell Biology Organization\| PubMed ID: 23634770	2013
A universal pedicle screw and V-rod system for lumbar isthmic spondylolysis: a retrospective analysis of 21 cases. PloS one\| PubMed ID: 23691090	2013
Cigarette smoke component acrolein modulates chromatin assembly by inhibiting histone acetylation. The Journal of biological chemistry\| PubMed ID: 23770671	2013
Improved heterologous erythromycin A production through expression plasmid re-design. Biotechnology progress\| PubMed ID: 23804312	2013
Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine. The Biochemical journal\| PubMed ID: 23849058	2013
Evaluation of the effects of food on the single-dose pharmacokinetics of trametinib, a first-in-class MEK inhibitor, in patients with cancer. Journal of clinical pharmacology\| PubMed ID: 23893461	2013
Large-scale separation of alkaloids from Gelsemium elegans by pH-zone-refining counter-current chromatography with a new solvent system screening method. Journal of chromatography. A\| PubMed ID: 23915643	2013
Adult Hirschsprung's disease: report of four cases. International journal of clinical and experimental pathology\| PubMed ID: 23923081	2013
Pneumocystis jiroveci pneumonia in patients with non-Hodgkin's lymphoma after Rituximab-containing regimen: two cases of report and literature review. Journal of thoracic disease\| PubMed ID: 23991330	2013
Synthesis and anticancer activity of some novel 2-phenazinamine derivatives. European journal of medicinal chemistry\| PubMed ID: 23995213	2013
Substrate selectivity of high-activity mutants of human butyrylcholinesterase. Organic & biomolecular chemistry\| PubMed ID: 24077614	2013
Degradation of atenolol by UV/peroxymonosulfate: kinetics, effect of operational parameters and mechanism. Chemosphere\| PubMed ID: 24083900	2013
Fundamental reaction pathway for peptide metabolism by proteasome: insights from first-principles quantum mechanical/molecular mechanical free energy calculations. The journal of physical chemistry. B\| PubMed ID: 24111489	2013
Platinum(II) complexes with N-monoalkyl 1R,2R-diaminocyclohexane derivatives as carrier ligands and 3-hydroxycyclobutane-1,1-dicarboxylate as a leaving group: potent cytotoxicity and DNA bin... European journal of medicinal chemistry\| PubMed ID: 24121235	2013
MARCH5 inactivation supports mitochondrial function during neurodegenerative stress. Frontiers in cellular neuroscience\| PubMed ID: 24133412	2013
De novo transcriptome profiling uncovers a drastic downregulation of photosynthesis upon nitrogen deprivation in the nonmodel green alga Botryosphaerella sudeticus. BMC genomics\| PubMed ID: 24138407	2013
Shuang-Huang-Lian exerts anti-inflammatory and anti-oxidative activities in lipopolysaccharide-stimulated murine alveolar macrophages. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 24192210	2014
Bisindole alkaloids with neural anti-inflammatory activity from Gelsemium elegans. Journal of natural products\| PubMed ID: 24256496	2013
Curcumol exhibits anti-inflammatory properties by interfering with the JNK-mediated AP-1 pathway in lipopolysaccharide-activated RAW264.7 cells. European journal of pharmacology\| PubMed ID: 24269960	2014
A model of glycosylated human butyrylcholinesterase. Molecular bioSystems\| PubMed ID: 24327294	2014
Ruthmycin, a new tetracyclic polyketide from Streptomyces sp. RM-4-15. Organic letters\| PubMed ID: 24341358	2014
Design, synthesis and anti-Alzheimer properties of dimethylaminomethyl-substituted curcumin derivatives. Bioorganic & medicinal chemistry letters\| PubMed ID: 24342238	2014
TLR2 mediates phagocytosis and autophagy through JNK signaling pathway in Staphylococcus aureus-stimulated RAW264.7 cells. Cellular signalling\| PubMed ID: 24412754	2014
Combination of amino acid/dipeptide with nitric oxide donating oleanolic acid derivatives as PepT1 targeting antitumor prodrugs. Journal of medicinal chemistry\| PubMed ID: 24422538	2014
Comparison of Uv/PDS and UV/H2O2 processes for the degradation of atenolol in water. Journal of environmental sciences (China)\| PubMed ID: 24520689	2013
Anti-inflammatory response following uptake of apoptotic bodies by meningothelial cells. Journal of neuroinflammation\| PubMed ID: 24565420	2014
Amino-acid mutations to extend the biological half-life of a therapeutically valuable mutant of human butyrylcholinesterase. Chemico-biological interactions\| PubMed ID: 24582612	2014
Design, synthesis and biological evaluation of D-ring opened galantamine analogs as multifunctional anti-Alzheimer agents. European journal of medicinal chemistry\| PubMed ID: 24594525	2014
Author Correction: PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy. Cell research\| PubMed ID: 30038297	2018
Concomitant oral and intravenous pharmacokinetics of trametinib, a MEK inhibitor, in subjects with solid tumours. British journal of clinical pharmacology\| PubMed ID: 24606567	2014
DNA microarray analysis reveals that antibiotic resistance-gene diversity in human gut microbiota is age related. Scientific reports\| PubMed ID: 24618772	2014
High performance all-polymer solar cell via polymer side-chain engineering. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 24664632	2014
Transmigration and phagocytosis of macrophages in an airway infection model using four-dimensional techniques. American journal of respiratory cell and molecular biology\| PubMed ID: 24678629	2014
Rhein exerts pro- and anti-inflammatory actions by targeting IKKβ inhibition in LPS-activated macrophages. Free radical biology & medicine\| PubMed ID: 24721152	2014
Suppressive effects of irisflorentin on LPS-induced inflammatory responses in RAW 264.7 macrophages. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 24740875	2014
Transcriptomic analysis of fiber strength in upland cotton chromosome introgression lines carrying different Gossypium barbadense chromosomal segments. PloS one\| PubMed ID: 24762562	2014
Integration of modeling and simulation to support changes to ondansetron dosing following a randomized, double-blind, placebo-, and active-controlled thorough QT study. Journal of clinical pharmacology\| PubMed ID: 24782199	2014
Genkwanin inhibits proinflammatory mediators mainly through the regulation of miR-101/MKP-1/MAPK pathway in LPS-activated macrophages. PloS one\| PubMed ID: 24800851	2014
Expression and effects of JMJD2A histone demethylase in endometrial carcinoma. Asian Pacific journal of cancer prevention : APJCP\| PubMed ID: 24815446	2014
Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification. ACS chemical biology\| PubMed ID: 24919140	2014
[Mechanism of signal molecule high mobility group box protein 1 mediated by Toll-like receptor 2 in murine asthma]. Zhonghua yi xue za zhi\| PubMed ID: 24924884	2014
Heat shock protein 70 from Trichinella spiralis induces protective immunity in BALB/c mice by activating dendritic cells. Vaccine\| PubMed ID: 24962751	2014
AR-regulated TWEAK-FN14 pathway promotes prostate cancer bone metastasis. Cancer research\| PubMed ID: 24970477	2014
High fever as an initial symptom of primary gastric inflammatory myofibroblastic tumor in an adult woman. International journal of clinical and experimental medicine\| PubMed ID: 24995114	2014
Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance. Oncotarget\| PubMed ID: 25004126	2014
Comparison of the endothelial toxicity induced by short-term amiodarone and diazepam exposure in a human umbilical vein endothelial cell line (EVC304). Pharmaceutical biology\| PubMed ID: 25026356	2014
Environmental-stress-induced Chromatin Regulation and its Heritability. Journal of carcinogenesis & mutagenesis\| PubMed ID: 25045581	2014
The new phase [Tl₄Sb₆Se₁₀][Sn₅Sb₂Se₁₄]: a naturally formed semiconducting heterostructure with two-dimensional conductance. Journal of the American Chemical Society\| PubMed ID: 25058471	2014
[Comparison on surface ultrastructure characteristic and drought resistance of different Trichosanthes kirilowii strains]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 25095361	2014
Assessment of the effect of ofatumumab on cardiac repolarization. Journal of clinical pharmacology\| PubMed ID: 25103870	2015
Implementation and evaluation of the chronic-disease self-management program among Chinese immigrant older adults in the U.S. Geriatric nursing (New York, N.Y.)\| PubMed ID: 25155476	2014
Lack of clinically significant pharmacokinetic interaction between the thrombopoietin receptor agonist eltrombopag and hepatitis C virus protease inhibitors boceprevir and telaprevir. Antimicrobial agents and chemotherapy\| PubMed ID: 25155600	2014
High-quality draft genome sequence of nematocidal Bacillus thuringiensis Sbt003. Standards in genomic sciences\| PubMed ID: 25197449	2014
Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression. The Journal of biological chemistry\| PubMed ID: 25266719	2014
Cotton fiber elongation network revealed by expression profiling of longer fiber lines introgressed with different Gossypium barbadense chromosome segments. BMC genomics\| PubMed ID: 25273845	2014
[Effects of plant-derived smoke water on accumulation of biomass and active substance of Salvia miltiorrhiza f. alba]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 25276963	2014
Design and synthesis of Lapatinib derivatives containing a branched side chain as HER1/HER2 targeting antitumor drug candidates. European journal of medicinal chemistry\| PubMed ID: 25305330	2014
The effect of flammer-syndrome on retinal venous pressure. BMC ophthalmology\| PubMed ID: 25312339	2014
Postsynthetic lanthanide functionalization of nanosized metal-organic frameworks for highly sensitive ratiometric luminescent thermometry. Chemical communications (Cambridge, England)\| PubMed ID: 25345472	2014
Application of chitosan microparticles for reduction of vibrio species in seawater and live oysters (Crassostrea virginica). Applied and environmental microbiology\| PubMed ID: 25381244	2015
Repeated inhalation of sevoflurane inhibits airway inflammation in an OVA-induced mouse model of allergic airway inflammation. Respirology (Carlton, Vic.)\| PubMed ID: 25399488	2015
Safety and efficacy of laparoscopy-assisted gastrectomy for advanced gastric cancer in the elderly. International journal of clinical and experimental medicine\| PubMed ID: 25419398	2014
The BRCA1/2-directed miRNA signature predicts a good prognosis in ovarian cancer patients with wild-type BRCA1/2. Oncotarget\| PubMed ID: 25537514	2015
Exploring the association between interleukin-1β and its interacting proteins in Alzheimer's disease. Molecular medicine reports\| PubMed ID: 25585621	2015
[Curative effects of kinesitherapy in combination with self-made simple orthosis in treatment of scar contracture of burned hand in children]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns\| PubMed ID: 25608782	2014
Two-dimensional mineral [Pb2BiS3][AuTe2]: high-mobility charge carriers in single-atom-thick layers. Journal of the American Chemical Society\| PubMed ID: 25612093	2015
Pharmacophore modeling using site-identification by ligand competitive saturation (SILCS) with multiple probe molecules. Journal of chemical information and modeling\| PubMed ID: 25622696	2015
Evaluation of the intestinal transport of a phenylethanoid glycoside-rich extract from Cistanche deserticola across the Caco-2 cell monolayer model. PloS one\| PubMed ID: 25646971	2015
Mapping functional group free energy patterns at protein occluded sites: nuclear receptors and G-protein coupled receptors. Journal of chemical information and modeling\| PubMed ID: 25692383	2015
Construction of stable polymeric vesicles based on azobenzene and beta-cyclodextrin grafted poly(glycerol methacrylate)s for potential applications in colon-specific drug delivery. Chemical communications (Cambridge, England)\| PubMed ID: 25692460	2015
Mitochondrial function in neuronal cells depends on p97/VCP/Cdc48-mediated quality control. Frontiers in cellular neuroscience\| PubMed ID: 25698929	2015
An Open-Label, Single-Arm, Phase 1 Study to Assess Biomarker Effects, Efficacy, and Safety of Ofatumumab in Patients With Refractory Chronic Lymphocytic Leukemia. Leukemia & lymphoma\| PubMed ID: 25721750	2015
[Study on secondary metabolites of endophytic fungi Penicillium polonicum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 25751949	2014
Loss of Androgen-Regulated MicroRNA 1 Activates SRC and Promotes Prostate Cancer Bone Metastasis. Molecular and cellular biology\| PubMed ID: 25802280	2015
A meta-analysis of the fusion rate from surgical treatment for odontoid factures: anterior odontoid screw versus posterior C1-C2 arthrodesis. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society\| PubMed ID: 25805577	2015
HOTAIR is a potential target for the treatment of cisplatin‑resistant ovarian cancer. Molecular medicine reports\| PubMed ID: 25824616	2015
Erratum for Wire et al., Lack of Clinically Significant Pharmacokinetic Interaction between the Thrombopoietin Receptor Agonist Eltrombopag and Hepatitis C Virus Protease Inhibitors Boceprev... Antimicrobial agents and chemotherapy\| PubMed ID: 25862822	2015
A Potential New Mechanism of Arsenic Carcinogenesis: Depletion of Stem-Loop Binding Protein and Increase in Polyadenylated Canonical Histone H3.1 mRNA. Biological trace element research\| PubMed ID: 25893362	2015
Sequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement. Nature biotechnology\| PubMed ID: 25893781	2015
Shuang-huang-lian attenuates lipopolysaccharide-induced acute lung injury in mice involving anti-inflammatory and antioxidative activities. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 25945107	2015
Mechanisms Underlying Acrolein-Mediated Inhibition of Chromatin Assembly. Molecular and cellular biology\| PubMed ID: 27669733	2016
The effects of acetaldehyde exposure on histone modifications and chromatin structure in human lung bronchial epithelial cells. Environmental and molecular mutagenesis\| PubMed ID: 29569274	2018
HSPA12A is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-mediated M1 Macrophage Polarization. Diabetes\| PubMed ID: 30455376	2018
A cytosolic chaperone complex controls folding and degradation of type III CD38. The Journal of biological chemistry\| PubMed ID: 30670591	2019
Evidence for a role of geranylgeranylation in renal angiomyolipoma and renal epithelioid angiomyolipoma. Oncology letters\| PubMed ID: 30675208	2019
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion. Journal of proteome research\| PubMed ID: 30901224	2019
The transferrin receptor CD71 regulates type II CD38, revealing tight topological compartmentalization of intracellular cyclic ADP-ribose production. The Journal of biological chemistry\| PubMed ID: 31434741	2019
CENP-A Ubiquitylation Is Indispensable to Cell Viability. Developmental cell\| PubMed ID: 31550462	2019
Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination. Frontiers in immunology\| PubMed ID: 31866999	2019
FAM134B oligomerization drives endoplasmic reticulum membrane scission for ER-phagy. The EMBO journal\| PubMed ID: 31930741	2020
Liver governs adipose remodelling via extracellular vesicles in response to lipid overload. Nature communications\| PubMed ID: 32024826	2020
Global Phosphoproteomic Analysis Reveals Significant Metabolic Reprogramming in the Termination of Liver Regeneration in Mice. Journal of proteome research\| PubMed ID: 32105074	2020