Patricia Sancho

Stem Cells & Cancer Group, Spanish National Cancer Research Center

Affiliated withSpanish National Cancer Research Center Queen Mary University of London Queen Mary University of London

Research Area

Biography

Patricia Sancho has not added Biography.
If you are Patricia Sancho and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 27	2015

Other Publications

Article	Year
Differential effects of catalase on apoptosis induction in human promonocytic cells. Relationships with heat-shock protein expression. Molecular pharmacology\| PubMed ID: 12606765	2003
12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extrac... The Journal of biological chemistry\| PubMed ID: 14610070	2004
Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukem... Blood\| PubMed ID: 15665116	2005
Pharmacological inhibitors of extracellular signal-regulated protein kinases attenuate the apoptotic action of cisplatin in human myeloid leukemia cells via glutathione-independent reduction... Biochimica et biophysica acta\| PubMed ID: 15843040	2005
Drp1 mediates caspase-independent type III cell death in normal and leukemic cells. Molecular and cellular biology\| PubMed ID: 17682056	2007
Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: role of reactive oxygen species production and glutathione de... Biochemical pharmacology\| PubMed ID: 18371937	2008
Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity. Journal of hepatology\| PubMed ID: 18845355	2008
The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expres... Biochimica et biophysica acta\| PubMed ID: 18848961	2009
Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeleton. Haematologica\| PubMed ID: 19278964	2009
Role of CXCR4/SDF-1 alpha in the migratory phenotype of hepatoma cells that have undergone epithelial-mesenchymal transition in response to the transforming growth factor-beta. Cellular signalling\| PubMed ID: 19586611	2009
Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-{beta}-induced cell death through impairing up-regulation of the NADPH oxidase NOX4. Cancer research\| PubMed ID: 19773433	2009
NADPH oxidase NOX1 controls autocrine growth of liver tumor cells through up-regulation of the epidermal growth factor receptor pathway. The Journal of biological chemistry\| PubMed ID: 20525691	2010
Snail1 suppresses TGF-beta-induced apoptosis and is sufficient to trigger EMT in hepatocytes. Journal of cell science\| PubMed ID: 20930141	2010
Dissecting the effect of targeting the epidermal growth factor receptor on TGF-β-induced-apoptosis in human hepatocellular carcinoma cells. Journal of hepatology\| PubMed ID: 21147185	2011
The NADPH oxidase inhibitor VAS2870 impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells. Biochemical pharmacology\| PubMed ID: 21276422	2011
Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli. Journal of cellular physiology\| PubMed ID: 21604268	2012
The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms. Biochemical pharmacology\| PubMed ID: 21864510	2011
Reciprocal regulation of NADPH oxidases and the cyclooxygenase-2 pathway. Free radical biology & medicine\| PubMed ID: 21907277	2011
Lack of amino acids in mouse hepatocytes in culture induces the selection of preneoplastic cells. Cellular signalling\| PubMed ID: 21964063	2012
Resilience and coping as predictors of general well-being in the elderly: a structural equation modeling approach. Aging & mental health\| PubMed ID: 22292552	2012
Protein-tyrosine phosphatase 1B (PTP1B) deficiency confers resistance to transforming growth factor-β (TGF-β)-induced suppressor effects in hepatocytes. The Journal of biological chemistry\| PubMed ID: 22427664	2012
Predicting perceived health in Angolan elderly: the moderator effect of being oldest old. Archives of gerontology and geriatrics\| PubMed ID: 22770711	2012
NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development. PloS one\| PubMed ID: 23049784	2012
Coping strategies: gender differences and development throughout life span. The Spanish journal of psychology\| PubMed ID: 23156917	2012
ROS production is essential for the apoptotic function of E2F1 in pheochromocytoma and neuroblastoma cell lines. PloS one\| PubMed ID: 23251571	2012
Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells. Hepatology (Baltimore, Md.)\| PubMed ID: 23813475	2013
TGF-beta signaling in cancer treatment. Current pharmaceutical design\| PubMed ID: 23944366	2014
Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells. PloS one\| PubMed ID: 24204632	2013
[Cost-consequence analysis of respiratory preventive intervention among institutionalized older people: randomized controlled trial]. Revista española de geriatría y gerontología\| PubMed ID: 24417971	2014
The NADPH oxidase NOX4 inhibits hepatocyte proliferation and liver cancer progression. Free radical biology & medicine\| PubMed ID: 24509161	2014
A mesenchymal-like phenotype and expression of CD44 predict lack of apoptotic response to sorafenib in liver tumor cells. International journal of cancer. Journal international du cancer\| PubMed ID: 25053293	2015
Nicotine Promotes Initiation and Progression of KRAS-Induced Pancreatic Cancer via Gata6-Dependent Dedifferentiation of Acinar Cells in Mice. Gastroenterology\| PubMed ID: 25127677	2014
Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment. Gut\| PubMed ID: 25841238	2015