Ouliana Ziouzenkova

Ouliana Ziouzenkova

Department of Human Sciences, The Ohio State University

Affiliated withThe Ohio State University

Research Area

Biography

Ouliana Ziouzenkova PhD is an Associate professor in the Department of Human Sciences, Human Nutrition program at the Ohio State University. She completed bachelor’s degree and Master's degree at the State University of Live, Ukraine. She received her PhD degree in Biochemistry from the University of Graz, Austria. She completed the postdoctoral training in School of Pharmacology at the University of Southern California and obtained molecular biology training at the Brigham and Women’s Hospital at Harvard University, Boston, MA. She is an Associate Editor at BMC Endocrine Disorders, and PloS One.

Dr. Ziouzenkova studies fundamental pathways regulating differentiation by vitamin A metabolites. These studies lead to discovery of a hormonal role of retinaldehyde in regulation of metabolic pathways. This metabolite of vitamin A can reprogram fat-storing into fat-burning, known as thermogenic fat tissues. The study in thermogenic adipocytes led to identification of novel proteins leading to weight loss, improve glucose metabolism in diabetes and protect from neurodegeneration. Her studies demonstrated that metabolic differences in women compared to men are largely under control of retinaldehyde and retinoic acid produced from vitamin A that led to obesity in postmenopausal period.

Now her goal is to translate these findings into development of new therapies treating obesity, diabetes, and neurodegenerative diseases, including Alzheimer’s dementia in people and pets. For these translational studies, the research team in her laboratory implemented nanotechnology in collaboration with Dr. Parquette and Dr. Lee from the Departments of Biochemistry and Chemical and Biomolecular Engineering at OSU. Ouliana Ziouzenkova is an author of 57 publications and 5 patents, her Google Scholar profile link is https://scholar.google.com/citations?user=BpA44cEAAAAJ&hl=en.

JoVE Journal Publications

ArticleTotal : 2
Year
Encapsulation Thermogenic Preadipocytes for Transplantation into Adipose Tissue Depots
Publication title

Cited by 6

2015
2022

Other Publications

Article
Year
Peroxisome proliferator-activated receptors.

Current atherosclerosis reports| PubMed ID: 11772424

2002
2002
2002
Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an antiinflammatory role for lipoprotein lipase.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 12606719

2003
2003
2003
Lipolytic PPAR activation: new insights into the intersection of triglycerides and inflammation?

Current opinion in clinical nutrition and metabolic care| PubMed ID: 15192437

2004
2004
2006
2007
2007
2008
2008
Concerted action of aldehyde dehydrogenases influences depot-specific fat formation.

Molecular endocrinology (Baltimore, Md.)| PubMed ID: 21436255

2011
The contribution of vitamin A to autocrine regulation of fat depots.

Biochimica et biophysica acta| PubMed ID: 21704731

2012
Retinoid and lipid metabolism.

Biochimica et biophysica acta| PubMed ID: 22153757

2012
2012
2013
2013
2013
2014
2013
2014
Enzymatic intracrine regulation of white adipose tissue.

Hormone molecular biology and clinical investigation| PubMed ID: 25390015

2014
2015
2016
2016
2016
2017
Induction of innervation by encapsulated adipocytes with engineered vitamin A metabolism.

Translational research : the journal of laboratory and clinical medicine| PubMed ID: 29144959

2018
2018
2018
2019
2019
2019
2020
Antibiotics in Food Chain: The Consequences for Antibiotic Resistance.

Antibiotics (Basel, Switzerland)| PubMed ID: 33066005

2020
2020
Paracardial fat remodeling affects systemic metabolism through alcohol dehydrogenase 1.

The Journal of clinical investigation| PubMed ID: 33586683

2021
2021
2022