Thomas Gaj

Departments of Chemistry and Cell and Molecular Biology, The Scripps Research Institute

Affiliated withThe Scripps Research Institute

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 14	2015

Other Publications

Article	Year
Highly selective cyclic peptide ligands for NeutrAvidin and avidin identified by phage display. Chemical biology & drug design\| PubMed ID: 16923020	2006
The AviD-tag, a NeutrAvidin/avidin specific peptide affinity tag for the immobilization and purification of recombinant proteins. Protein expression and purification\| PubMed ID: 17697784	2007
Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A. Journal of the American Chemical Society\| PubMed ID: 17944472	2007
Directed evolution of recombinase specificity by split gene reassembly. Nucleic acids research\| PubMed ID: 20194120	2010
Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases. Journal of molecular biology\| PubMed ID: 20447404	2010
Structure-guided reprogramming of serine recombinase DNA sequence specificity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21187418	2011
Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase. Nucleic acids research\| PubMed ID: 21653554	2011
Targeted gene knockout by direct delivery of zinc-finger nuclease proteins. Nature methods\| PubMed ID: 22751204	2012
Chimeric TALE recombinases with programmable DNA sequence specificity. Nucleic acids research\| PubMed ID: 23019222	2012
A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells. Nucleic acids research\| PubMed ID: 23393187	2013
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends in biotechnology\| PubMed ID: 23664777	2013
Expanding the scope of site-specific recombinases for genetic and metabolic engineering. Biotechnology and bioengineering\| PubMed ID: 23982993	2014
Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors. ACS synthetic biology\| PubMed ID: 24251925	2014
Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants. Nucleic acids research\| PubMed ID: 24452803	2014
Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering. PloS one\| PubMed ID: 24465685	2014
Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign. Journal of the American Chemical Society\| PubMed ID: 24611715	2014
Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies. Accounts of chemical research\| PubMed ID: 24877793	2014
Protein delivery using Cys2-His2 zinc-finger domains. ACS chemical biology\| PubMed ID: 24936957	2014
Site-selective labeling of a lysine residue in human serum albumin. Angewandte Chemie (International ed. in English)\| PubMed ID: 25196737	2014
Genome engineering with custom recombinases. Methods in enzymology\| PubMed ID: 25398336	2014
Improved cell-penetrating zinc-finger nuclease proteins for precision genome engineering. Molecular therapy. Nucleic acids\| PubMed ID: 25756962	2015