Mario Losen

School for Mental Health and Neuroscience, Maastricht University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2015

Other Publications

Article	Year
Effect of oxygen supply on passaging, stabilising and screening of recombinant Hansenula polymorpha production strains in test tube cultures. FEMS yeast research\| PubMed ID: 14613884	2003
Effect of oxygen limitation and medium composition on Escherichia coli fermentation in shake-flask cultures. Biotechnology progress\| PubMed ID: 15296430	2004
DGAT1 overexpression in muscle by in vivo DNA electroporation increases intramyocellular lipid content. Journal of lipid research\| PubMed ID: 15576838	2005
Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis. Brain : a journal of neurology\| PubMed ID: 16150851	2005
Overexpression of rapsyn in rat muscle increases acetylcholine receptor levels in chronic experimental autoimmune myasthenia gravis. The American journal of pathology\| PubMed ID: 17255332	2007
Improvement of in vivo transfer of plasmid DNA in muscle: comparison of electroporation versus ultrasound. Drug delivery\| PubMed ID: 17613014	2007
Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange. Science (New York, N.Y.)\| PubMed ID: 17872445	2007
Generation of polyclonal antibodies directed against G protein-coupled receptors using electroporation-aided DNA immunization. Journal of pharmacological and toxicological methods\| PubMed ID: 18261934	2008
Treatment of myasthenia gravis by preventing acetylcholine receptor modulation. Annals of the New York Academy of Sciences\| PubMed ID: 18567867	2008
Immunosuppression of experimental autoimmune myasthenia gravis by mycophenolate mofetil. Journal of neuroimmunology\| PubMed ID: 18667242	2008
Silencing rapsyn in vivo decreases acetylcholine receptors and augments sodium channels and secondary postsynaptic membrane folding. Neurobiology of disease\| PubMed ID: 19344765	2009
The expression of the Goodpasture antigen-binding protein (ceramide transporter) in adult rat brain. Journal of chemical neuroanatomy\| PubMed ID: 19555756	2009
The effect of plasma from muscle-specific tyrosine kinase myasthenia patients on regenerating endplates. The American journal of pathology\| PubMed ID: 19745065	2009
Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivi... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19890000	2009
The ceramide transporter and the Goodpasture antigen binding protein: one protein--one function? Journal of neurochemistry\| PubMed ID: 20236389	2010
The auto-antigen repertoire in myasthenia gravis. Autoimmunity\| PubMed ID: 20380581	2010
Antibody effector mechanisms in myasthenia gravis-pathogenesis at the neuromuscular junction. Autoimmunity\| PubMed ID: 20380584	2010
Low Current-driven Micro-electroporation Allows Efficient In Vivo Delivery of Nonviral DNA into the Adult Mouse Brain. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 20389292	2010
In vivo electroporation of the central nervous system: a non-viral approach for targeted gene delivery. Progress in neurobiology\| PubMed ID: 20937354	2010
Reduced thymic expression of ErbB receptors without auto-antibodies against synaptic ErbB in myasthenia gravis. Journal of neuroimmunology\| PubMed ID: 21168922	2011
Proteasome inhibition with bortezomib depletes plasma cells and autoantibodies in experimental autoimmune myasthenia gravis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21239719	2011
Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle. PloS one\| PubMed ID: 21264296	2011
Neuropathy-induced spinal GAP-43 expression is not a main player in the onset of mechanical pain hypersensitivity. Journal of neurotrauma\| PubMed ID: 21671799	2011
Unchanged expression of the ceramide transfer protein in the acute 6-OHDA neurodegenerative model. Neuroscience letters\| PubMed ID: 22040672	2012
The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria. Histochemistry and cell biology\| PubMed ID: 22127648	2012
Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice. Brain : a journal of neurology\| PubMed ID: 22396395	2012
Goodpasture antigen-binding protein/ceramide transporter binds to human serum amyloid P-component and is present in brain amyloid plaques. The Journal of biological chemistry\| PubMed ID: 22396542	2012
MuSK myasthenia gravis and Lambert-Eaton myasthenic syndrome in the same patient. Clinical neurology and neurosurgery\| PubMed ID: 22421253	2012
Targeting plasma cells with proteasome inhibitors: possible roles in treating myasthenia gravis? Annals of the New York Academy of Sciences\| PubMed ID: 23252897	2012
Pathophysiology of myasthenia gravis with antibodies to the acetylcholine receptor, muscle-specific kinase and low-density lipoprotein receptor-related protein 4. Autoimmunity reviews\| PubMed ID: 23535160	2013
Autoantigen induced clonal expansion in immortalized B cells from the peripheral blood of multiple sclerosis patients. Journal of neuroimmunology\| PubMed ID: 23746373	2013
Proteomic analysis of rat tibialis anterior muscles at different stages of experimental autoimmune myasthenia gravis. Journal of neuroimmunology\| PubMed ID: 23791150	2013
Autoantibodies to neurotransmitter receptors and ion channels: from neuromuscular to neuropsychiatric disorders. Frontiers in genetics\| PubMed ID: 24065983	2013
Muscle disuse atrophy is not accompanied by changes in skeletal muscle satellite cell content. Clinical science (London, England : 1979)\| PubMed ID: 24215591	2014
MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24297891	2013
Complement activation by ceramide transporter proteins. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24395916	2014
Clonal heterogeneity of thymic B cells from early-onset myasthenia gravis patients with antibodies against the acetylcholine receptor. Journal of autoimmunity\| PubMed ID: 24439114	2014
Delivery of DNA into the central nervous system via electroporation. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24510821	2014
Proteasome inhibition with bortezomib depletes plasma cells and specific autoantibody production in primary thymic cell cultures from early-onset myasthenia gravis patients. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24973445	2014
Glycine receptor antibodies in PERM: a new channelopathy. Brain : a journal of neurology\| PubMed ID: 25057131	2014
Ex vivo and in vivo administration of fluorescent CNA35 specifically marks cardiac fibrosis. Molecular imaging\| PubMed ID: 25249247	2014
IL-17-producing CD4(+) T cells contribute to the loss of B-cell tolerance in experimental autoimmune myasthenia gravis. European journal of immunology\| PubMed ID: 25676041	2015
Guidelines for pre-clinical assessment of the acetylcholine receptor-specific passive transfer myasthenia gravis model-Recommendations for methods and experimental designs. Experimental neurology\| PubMed ID: 25743217	2015
Standardization of the experimental autoimmune myasthenia gravis (EAMG) model by immunization of rats with Torpedo californica acetylcholine receptors - Recommendations for methods and exper... Experimental neurology\| PubMed ID: 25796590	2015
Detection of Peptide-based nanoparticles in blood plasma by ELISA. PloS one\| PubMed ID: 25996618	2015