Christoph E. Hagemeyer

Vascular Biotechnology Laboratory, Baker IDI Heart and Diabetes Institute

Affiliated withBaker IDI Heart and Diabetes Institute

Research Area

Biography

Christoph E. Hagemeyer has not added Biography.
If you are Christoph E. Hagemeyer and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 49	2015

Other Publications

Article	Year
Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons. The Journal of comparative neurology\| PubMed ID: 12271488	2002
Fibrin-targeted direct factor Xa inhibition: construction and characterization of a recombinant factor Xa inhibitor composed of an anti-fibrin single-chain antibody and tick anticoagulant pe... Thrombosis and haemostasis\| PubMed ID: 15213844	2004
Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets. Circulation research\| PubMed ID: 16778135	2006
A mechanistic model for paradoxical platelet activation by ligand-mimetic alphaIIb beta3 (GPIIb/IIIa) antagonists. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17170374	2007
Targeting ligand-induced binding sites on GPIIb/IIIa via single-chain antibody allows effective anticoagulation without bleeding time prolongation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17322097	2007
Single-chain antibodies as new antithrombotic drugs. Seminars in thrombosis and hemostasis\| PubMed ID: 17340468	2007
Single-chain antibodies as diagnostic tools and therapeutic agents. Thrombosis and haemostasis\| PubMed ID: 19492141	2009
Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques. Circulation research\| PubMed ID: 19520972	2009
Ex-vivo thrombolytic gene therapy for vein graft patency: the frontier for development of selective, localised therapeutic approaches. Thrombosis and haemostasis\| PubMed ID: 19572059	2009
7-Benzyloxyresorufin-O-dealkylase activity as a marker for measuring cytochrome P450 CYP3A induction in mouse liver. Analytical biochemistry\| PubMed ID: 19903449	2010
Genetic transfer of fusion proteins effectively inhibits VCAM-1-mediated cell adhesion and transmigration via inhibition of cytoskeletal anchorage. Journal of cellular and molecular medicine\| PubMed ID: 20414973	2010
MRI of inducible P-selectin expression in human activated platelets involved in the early stages of atherosclerosis. NMR in biomedicine\| PubMed ID: 21192086	2011
Targeting the platelet integrin GPIIb/IIIa. Current pharmaceutical design\| PubMed ID: 21247395	2010
Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody. PloS one\| PubMed ID: 21479193	2011
GPVI and GPIbα mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors. PloS one\| PubMed ID: 21552524	2011
An activation-specific platelet inhibitor that can be turned on/off by medically used hypothermia. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21659646	2011
Novel single-chain antibody-targeted microbubbles for molecular ultrasound imaging of thrombosis: validation of a unique noninvasive method for rapid and sensitive detection of thrombi and m... Circulation\| PubMed ID: 22647975	2012
Bio-Click Chemistry: Enzymatic Functionalization of PEGylated Capsules for Targeting Applications. Angewandte Chemie (International ed. in English)\| PubMed ID: 22744941	2012
Enzymatic antibody tagging: toward a universal biocompatible targeting tool. Trends in cardiovascular medicine\| PubMed ID: 22889584	2012
Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding? Blood\| PubMed ID: 23380744	2013
Detection of activated platelets in a mouse model of carotid artery thrombosis with 18 F-labeled single-chain antibodies. Nuclear medicine and biology\| PubMed ID: 24440583	2014
Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets. Circulation research\| PubMed ID: 24508759	2014
Engineering multifunctional capsules through the assembly of metal-phenolic networks. Angewandte Chemie (International ed. in English)\| PubMed ID: 24700671	2014
Enzyme-mediated site-specific bioconjugation of metal complexes to proteins: sortase-mediated coupling of copper-64 to a single-chain antibody. Angewandte Chemie (International ed. in English)\| PubMed ID: 24777818	2014
Single-chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets. Molecular pharmaceutics\| PubMed ID: 24999533	2014
Particle generation, functionalization and sortase A-mediated modification with targeting of single-chain antibodies for diagnostic and therapeutic use. Nature protocols\| PubMed ID: 25502886	2015
Targeted antithrombotic protein micelles. Angewandte Chemie (International ed. in English)\| PubMed ID: 25504546	2015
Engineering poly(ethylene glycol) particles for improved biodistribution. ACS nano\| PubMed ID: 25712853	2015
A Versatile Approach for the Site-Specific Modification of Recombinant Antibodies Using a Combination of Enzyme-Mediated Bioconjugation and Click Chemistry. Angewandte Chemie (International ed. in English)\| PubMed ID: 25962581	2015
Boronate-Phenolic Network Capsules with Dual Response to Acidic pH and cis-Diols. Advanced healthcare materials\| PubMed ID: 26088356	2015