Christopher E. Turner

Department of Cell & Developmental Biology, SUNY Upstate Medical University

Affiliated withSUNY Upstate Medical University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2015

Other Publications

Article	Year
Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization. The Journal of biological chemistry\| PubMed ID: 11694518	2002
The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling. Molecular and cellular biology\| PubMed ID: 11784865	2002
The paxillin LD motifs. FEBS letters\| PubMed ID: 11911889	2002
A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration. The Journal of biological chemistry\| PubMed ID: 11919182	2002
Epidermal growth factor stimulates serine/threonine phosphorylation of the focal adhesion protein paxillin in a MEK-dependent manner in normal rat kidney cells. Journal of cellular physiology\| PubMed ID: 11920684	2002
Actopaxin is phosphorylated during mitosis and is a substrate for cyclin B1/cdc2 kinase. The Biochemical journal\| PubMed ID: 11931650	2002
Roles for the tubulin- and PTP-PEST-binding paxillin LIM domains in cell adhesion and motility. The international journal of biochemistry & cell biology\| PubMed ID: 11950600	2002
Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway. Molecular biology of the cell\| PubMed ID: 12006652	2002
Ca2+-dependent localization of integrin-linked kinase to cell junctions in differentiating keratinocytes. The Journal of biological chemistry\| PubMed ID: 12547824	2003
Extracellular signal-regulated kinase mediates phosphorylation of tropomyosin-1 to promote cytoskeleton remodeling in response to oxidative stress: impact on membrane blebbing. Molecular biology of the cell\| PubMed ID: 12686598	2003
Crk associates with a multimolecular Paxillin/GIT2/beta-PIX complex and promotes Rac-dependent relocalization of Paxillin to focal contacts. Molecular biology of the cell\| PubMed ID: 12857867	2003
RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization. Molecular and cellular biology\| PubMed ID: 12861019	2003
Expression of non-phosphorylatable paxillin mutants in canine tracheal smooth muscle inhibits tension development. The Journal of physiology\| PubMed ID: 12949231	2003
Tension development during contractile stimulation of smooth muscle requires recruitment of paxillin and vinculin to the membrane. American journal of physiology. Cell physiology\| PubMed ID: 14576084	2004
FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nature cell biology\| PubMed ID: 14743221	2004
Integrin-linked kinase: a possible role in scar contracture. Annals of plastic surgery\| PubMed ID: 14745274	2004
EphB1-mediated cell migration requires the phosphorylation of paxillin at Tyr-31/Tyr-118. The Journal of biological chemistry\| PubMed ID: 15107421	2004
Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility. The Journal of cell biology\| PubMed ID: 15138291	2004
Phosphorylation of actopaxin regulates cell spreading and migration. The Journal of cell biology\| PubMed ID: 15353548	2004
Paxillin: adapting to change. Physiological reviews\| PubMed ID: 15383653	2004
The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner. The Journal of biological chemistry\| PubMed ID: 15485819	2004
Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin. The Journal of biological chemistry\| PubMed ID: 15817463	2005
Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness. Molecular biology of the cell\| PubMed ID: 16000375	2005
Tyrosine-phosphorylated Hic-5 inhibits epidermal growth factor-induced lamellipodia formation. Experimental cell research\| PubMed ID: 16183059	2005
Regulation of paxillin family members during epithelial-mesenchymal transformation: a putative role for paxillin delta. Journal of cell science\| PubMed ID: 16219691	2005
Paxillin is essential for PTP-PEST-dependent regulation of cell spreading and motility: a role for paxillin kinase linker. Journal of cell science\| PubMed ID: 16317044	2005
CdGAP associates with actopaxin to regulate integrin-dependent changes in cell morphology and motility. Current biology : CB\| PubMed ID: 16860736	2006
Hic-5 contributes to epithelial-mesenchymal transformation through a RhoA/ROCK-dependent pathway. Journal of cellular physiology\| PubMed ID: 17299801	2007
TGF-beta1 slows the growth of pathogenic myofibroblasts through a mechanism requiring the focal adhesion protein, Hic-5. The Journal of investigative dermatology\| PubMed ID: 17671518	2008
Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites. Journal of cell science\| PubMed ID: 18187451	2008
Hic-5 promotes the hypertrophic scar myofibroblast phenotype by regulating the TGF-beta1 autocrine loop. The Journal of investigative dermatology\| PubMed ID: 18401422	2008
Paxillin comes of age. Journal of cell science\| PubMed ID: 18650496	2008
Cross talk between paxillin and Rac is critical for mediation of barrier-protective effects by oxidized phospholipids. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 18676874	2008
FAK engages multiple pathways to maintain survival of fibroblasts and epithelia: differential roles for paxillin and p130Cas. Journal of cell science\| PubMed ID: 19126677	2009
Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration. Molecular biology of the cell\| PubMed ID: 19776348	2009
Emerging role of paxillin-PKL in regulation of cell adhesion, polarity and migration. Cell adhesion & migration\| PubMed ID: 20372092	2010
The cell adhesion-associated protein Git2 regulates morphogenetic movements during zebrafish embryonic development. Developmental biology\| PubMed ID: 21034731	2011
Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis. Molecular biology of the cell\| PubMed ID: 21148292	2011
LNK (SH2B3) is a key regulator of integrin signaling in endothelial cells and targets α-parvin to control cell adhesion and migration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22441983	2012
Hic-5 promotes invadopodia formation and invasion during TGF-β-induced epithelial-mesenchymal transition. The Journal of cell biology\| PubMed ID: 22529104	2012
Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA. PloS one\| PubMed ID: 22629471	2012
CdGAP regulates cell migration and adhesion dynamics in two-and three-dimensional matrix environments. Cytoskeleton (Hoboken, N.J.)\| PubMed ID: 22907917	2012
Actopaxin (α-parvin) phosphorylation is required for matrix degradation and cancer cell invasion. The Journal of biological chemistry\| PubMed ID: 22955285	2012
Beta2-adaptin binds actopaxin and regulates cell spreading, migration and matrix degradation. PloS one\| PubMed ID: 23056266	2012
Diverse roles for the paxillin family of proteins in cancer. Genes & cancer\| PubMed ID: 23226574	2012
Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migration. Molecular biology of the cell\| PubMed ID: 23615439	2013
LIM domains target actin regulators paxillin and zyxin to sites of stress fiber strain. PloS one\| PubMed ID: 23990882	2013
The focal adhesion-localized CdGAP regulates matrix rigidity sensing and durotaxis. PloS one\| PubMed ID: 24632816	2014
Paxillin inhibits HDAC6 to regulate microtubule acetylation, Golgi structure, and polarized migration. The Journal of cell biology\| PubMed ID: 25070956	2014