Jen-Tsan Chi

Department of Molecular Genetics and Microbiology, Duke University School of Medicine

Affiliated withDuke University School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2015

Other Publications

Article	Year
Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines. Oncogene\| PubMed ID: 12226758	2002
Diversity, topographic differentiation, and positional memory in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12297622	2002
Genomewide view of gene silencing by small interfering RNAs. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12730368	2003
Endothelial cell diversity revealed by global expression profiling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12963823	2003
Systemic and cell type-specific gene expression patterns in scleroderma skin. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14530402	2003
Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS biology\| PubMed ID: 14737219	2004
Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. PLoS medicine\| PubMed ID: 16417408	2006
Lysyl oxidase is essential for hypoxia-induced metastasis. Nature\| PubMed ID: 16642001	2006
Predicting a local recurrence after breast-conserving therapy by gene expression profiling. Breast cancer research : BCR\| PubMed ID: 17069664	2006
The potential role of intrinsic hypoxia markers as prognostic variables in cancer. Antioxidants & redox signaling\| PubMed ID: 17571959	2007
Gene expression programs of human smooth muscle cells: tissue-specific differentiation and prognostic significance in breast cancers. PLoS genetics\| PubMed ID: 17907811	2007
A viral microRNA functions as an orthologue of cellular miR-155. Nature\| PubMed ID: 18075594	2007
Modeling cancer progression via pathway dependencies. PLoS computational biology\| PubMed ID: 18282083	2008
The genomic analysis of erythrocyte microRNA expression in sickle cell diseases. PloS one\| PubMed ID: 18523662	2008
Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 18715778	2008
The genomic analysis of lactic acidosis and acidosis response in human cancers. PLoS genetics\| PubMed ID: 19057672	2008
Cross-study projections of genomic biomarkers: an evaluation in cancer genomics. PloS one\| PubMed ID: 19225561	2009
Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. Cancer cell\| PubMed ID: 19477431	2009
Minimizing off-target effects by using diced siRNAs for RNA interference. Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research\| PubMed ID: 19771225	2006
p38gamma mitogen-activated protein kinase is a key regulator in skeletal muscle metabolic adaptation in mice. PloS one\| PubMed ID: 19936205	2009
Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. Nature medicine\| PubMed ID: 20305662	2010
microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease. Blood\| PubMed ID: 20709907	2010
Latent factor analysis to discover pathway-associated putative segmental aneuploidies in human cancers. PLoS computational biology\| PubMed ID: 20824128	2010
Isolation and characterization of microRNAs of human mature erythrocytes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20827535	2010
Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. PLoS genetics\| PubMed ID: 20844768	2010
AN INTEGRATIVE ANALYSIS OF CANCER GENE EXPRESSION STUDIES USING BAYESIAN LATENT FACTOR MODELING. The annals of applied statistics\| PubMed ID: 20953268	2009
Comparison of genomics and functional imaging from canine sarcomas treated with thermoradiotherapy predicts therapeutic response and identifies combination therapeutics. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21292819	2011
Polysome profiling of the malaria parasite Plasmodium falciparum. Molecular and biochemical parasitology\| PubMed ID: 21605599	2011
Analysis of tumor environmental response and oncogenic pathway activation identifies distinct basal and luminal features in HER2-related breast tumor subtypes. Breast cancer research : BCR\| PubMed ID: 21672245	2011
Whole blood gene expression analyses in patients with single versus recurrent venous thromboembolism. Thrombosis research\| PubMed ID: 21737128	2011
Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality. Science translational medicine\| PubMed ID: 21813754	2011
Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia. PLoS genetics\| PubMed ID: 21852960	2011
Functional interaction between responses to lactic acidosis and hypoxia regulates genomic transcriptional outputs. Cancer research\| PubMed ID: 22135092	2012
Time-dependent changes in non-COX-1-dependent platelet function with daily aspirin therapy. Journal of thrombosis and thrombolysis\| PubMed ID: 22294277	2012
A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. Genome research\| PubMed ID: 22899282	2012
Translocation of sickle cell erythrocyte microRNAs into Plasmodium falciparum inhibits parasite translation and contributes to malaria resistance. Cell host & microbe\| PubMed ID: 22901539	2012
Associations between Intake of Folate, Methionine, and Vitamins B-12, B-6 and Prostate Cancer Risk in American Veterans. Journal of cancer epidemiology\| PubMed ID: 22927849	2012
Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23045699	2012
Iron-responsive miR-485-3p regulates cellular iron homeostasis by targeting ferroportin. PLoS genetics\| PubMed ID: 23593016	2013
Acidosis activation of the proton-sensing GPR4 receptor stimulates vascular endothelial cell inflammatory responses revealed by transcriptome analysis. PloS one\| PubMed ID: 23613998	2013
Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events. Journal of the American College of Cardiology\| PubMed ID: 23831034	2013
Understanding the tumor microenvironment and radioresistance by combining functional imaging with global gene expression. Seminars in radiation oncology\| PubMed ID: 24012344	2013
Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer. PloS one\| PubMed ID: 24069390	2013
Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression. The Journal of clinical investigation\| PubMed ID: 24334454	2014
Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress. Cancer & metabolism\| PubMed ID: 24359630	2013
A joint analysis of metabolomics and genetics of breast cancer. Breast cancer research : BCR\| PubMed ID: 25091696	2014
Glycolysis-dependent histone deacetylase 4 degradation regulates inflammatory cytokine production. Molecular biology of the cell\| PubMed ID: 25187650	2014
Utilization of the Eμ-Myc mouse to model heterogeneity of therapeutic response. Molecular cancer therapeutics\| PubMed ID: 25349303	2014
Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78. Molecular cancer therapeutics\| PubMed ID: 25589495	2015
Whole blood gene expression profiles distinguish clinical phenotypes of venous thromboembolism. Thrombosis research\| PubMed ID: 25684211	2015
Alternative fuels for cancer cells. Cancer journal (Sudbury, Mass.)\| PubMed ID: 25815843	2015
Comprehensive profiling of amino acid response uncovers unique methionine-deprived response dependent on intact creatine biosynthesis. PLoS genetics\| PubMed ID: 25849282	2015
An unexpected alliance between stress responses to drive oncogenesis. Breast cancer research : BCR\| PubMed ID: 25927911	2014
E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program. PloS one\| PubMed ID: 26039627	2015
Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 26071485	2015
Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis. PloS one\| PubMed ID: 26075887	2015
Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers. International journal of radiation oncology, biology, physics\| PubMed ID: 26104938	2015
Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma. Cell reports\| PubMed ID: 26119730	2015
A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models. Nature communications\| PubMed ID: 26239362	2015
Synthesis and Biological Evaluation of Manassantin Analogues for Hypoxia-Inducible Factor 1α Inhibition. Journal of medicinal chemistry\| PubMed ID: 26394152	2015
ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate. PLoS genetics\| PubMed ID: 26452058	2015
FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target. Radiation research\| PubMed ID: 26488758	2015
A comprehensive joint analysis of the long and short RNA transcriptomes of human erythrocytes. BMC genomics\| PubMed ID: 26573221	2015