Jun Fujita

Department of Cardiology, Keio University School of Medicine

Affiliated withKeio University School of Medicine

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 11	2015

Other Publications

Article	Year
Gankyrin is an ankyrin-repeat oncoprotein that interacts with CDK4 kinase and the S6 ATPase of the 26 S proteasome. The Journal of biological chemistry\| PubMed ID: 11779854	2002
Invited review: Effects of heat and cold stress on mammalian gene expression. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 11896043	2002
Secreted frizzled related protein 1 is overexpressed in uterine leiomyomas, associated with a high estrogenic environment and unrelated to proliferative activity. The Journal of clinical endocrinology and metabolism\| PubMed ID: 11932307	2002
Ouabain suppresses glucose-induced mitochondrial ATP production and insulin release by generating reactive oxygen species in pancreatic islets. Diabetes\| PubMed ID: 12145166	2002
A novel protein overexpressed in hepatoma accelerates export of NF-kappa B from the nucleus and inhibits p53-dependent apoptosis. Cancer cell\| PubMed ID: 12398897	2002
MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity. The Journal of biological chemistry\| PubMed ID: 12525503	2003
Increased islet apoptosis in Pdx1+/- mice. The Journal of clinical investigation\| PubMed ID: 12697734	2003
Cyclic AMP enhances the expression of an extravillous trophoblast marker, melanoma cell adhesion molecule, in choriocarcinoma cell JEG3 and human chorionic villous explant cultures. Molecular human reproduction\| PubMed ID: 12771237	2003
Expression of cold-inducible RNA-binding protein in the normal endometrium, endometrial hyperplasia, and endometrial carcinoma. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists\| PubMed ID: 12819390	2003
Crystallization of gankyrin, an oncoprotein that interacts with CDK4 and the S6b (rpt3) ATPase of the 19S regulator of the 26S proteasome. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 12832791	2003
Role of a novel oncogenic protein, gankyrin, in hepatocyte proliferation. Journal of gastroenterology\| PubMed ID: 14505129	2003
PEP-19 overexpression in human uterine leiomyoma. Molecular human reproduction\| PubMed ID: 14561813	2003
The crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53. The Journal of biological chemistry\| PubMed ID: 14573599	2004
Engineered long terminal repeats of retroviral vectors enhance transgene expression in hepatocytes in vitro and in vivo. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 14599813	2003
Recruitment of bone marrow-derived endothelial cells to sites of pancreatic beta-cell injury. Diabetes\| PubMed ID: 14693702	2004
A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells. The Journal of biological chemistry\| PubMed ID: 14739298	2004
Apg-2 has a chaperone-like activity similar to Hsp110 and is overexpressed in hepatocellular carcinomas. FEBS letters\| PubMed ID: 14987991	2004
Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression. The Journal of clinical investigation\| PubMed ID: 15067320	2004
Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism. Journal of cell science\| PubMed ID: 15075239	2004
Cardiomyocytes undergo cells division following myocardial infarction is a spatially and temporally restricted event in rats. Molecular and cellular biochemistry\| PubMed ID: 15124922	2004
[The regenerative therapy of heart failure with adult stem cells and cell transplantation]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics\| PubMed ID: 15148747	2004
Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction. Blood\| PubMed ID: 15297308	2004
Increased expression of calcium-binding protein S100 in human uterine smooth muscle tumours. Molecular human reproduction\| PubMed ID: 15322223	2004
Purified cardiomyocytes from bone marrow mesenchymal stem cells produce stable intracardiac grafts in mice. Cardiovascular research\| PubMed ID: 15639472	2005
[A case of early esophageal adenocarcinoma arising from cardiac glands, resected by endoscopic mucosal resection]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology\| PubMed ID: 15651393	2004
Bone marrow-derived cells contribute to pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension. Chest\| PubMed ID: 15888860	2005
Analysis of the electrophysiological properties and arrhythmias in directly contacted skeletal and cardiac muscle cell sheets. Cardiovascular research\| PubMed ID: 15904904	2005
Low temperature protects mammalian cells from apoptosis initiated by various stimuli in vitro. Experimental cell research\| PubMed ID: 16018998	2005
The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53. Cancer cell\| PubMed ID: 16023600	2005
A novel protein Depp, which is induced by progesterone in human endometrial stromal cells activates Elk-1 transcription factor. Molecular human reproduction\| PubMed ID: 16123073	2005
The oncoprotein gankyrin negatively regulates both p53 and RB by enhancing proteasomal degradation. Cell cycle (Georgetown, Tex.)\| PubMed ID: 16177571	2005
Mesenchymal, but not hematopoietic, stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction in mice. Kidney international\| PubMed ID: 16221170	2005
Administration of hematopoietic cytokines in the subacute phase after cerebral infarction is effective for functional recovery facilitating proliferation of intrinsic neural stem/progenitor ... Circulation\| PubMed ID: 16461843	2006
Cirp protects against tumor necrosis factor-alpha-induced apoptosis via activation of extracellular signal-regulated kinase. Biochimica et biophysica acta\| PubMed ID: 16569452	2006
Gankyrin: a new oncoprotein and regulator of pRb and p53. Trends in cell biology\| PubMed ID: 16581249	2006
In vivo selection of transduced hematopoietic stem cells and little evidence of their conversion into hepatocytes in vivo. Journal of hepatology\| PubMed ID: 16837099	2006
G-CSF and HGF: combination of vasculogenesis and angiogenesis synergistically improves recovery in murine hind limb ischemia. Journal of molecular and cellular cardiology\| PubMed ID: 17223129	2007
Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1. The Journal of biological chemistry\| PubMed ID: 17353187	2007
Administration of granulocyte colony-stimulating factor after myocardial infarction enhances the recruitment of hematopoietic stem cell-derived myofibroblasts and contributes to cardiac repa... Stem cells (Dayton, Ohio)\| PubMed ID: 17690181	2007
Bone marrow derived cells are involved in the pathogenesis of cardiac hypertrophy in response to pressure overload. Circulation\| PubMed ID: 17698734	2007
The oncoprotein gankyrin interacts with RelA and suppresses NF-kappaB activity. Biochemical and biophysical research communications\| PubMed ID: 17904523	2007
Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance. International journal of cancer. Journal international du cancer\| PubMed ID: 17935131	2008
Dose-dependent differential regulation of cytokine secretion from macrophages by fractalkine. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18025192	2007
Association of gankyrin protein expression with early clinical stages and insulin-like growth factor-binding protein 5 expression in human hepatocellular carcinoma. Hepatology (Baltimore, Md.)\| PubMed ID: 18161051	2008
[Nationwide surveillance of parenteral antibiotics containing meropenem activities against clinically isolated strains in 2006]. The Japanese journal of antibiotics\| PubMed ID: 18447206	2007
Epidemiology of sporadic (non-epidemic) cases of Trichophyton tonsurans infection in Japan based on PCR-RFLP analysis of non-transcribed spacer region of ribosomal RNA gene. Japanese journal of infectious diseases\| PubMed ID: 18503175	2008
Caspase activity mediates the differentiation of embryonic stem cells. Cell stem cell\| PubMed ID: 18522852	2008
Analysis of gene and protein expression of cytochrome P450 and stress-associated molecules in rat liver after spaceflight. Pathology international\| PubMed ID: 18801074	2008
G-CSF augments small vessel and cell density in canine myocardial infarciton. The Keio journal of medicine\| PubMed ID: 18854666	2008
Human T-cell leukemia virus type I tax down-regulates the expression of phosphatidylinositol 3,4,5-trisphosphate inositol phosphatases via the NF-kappaB pathway. The Journal of biological chemistry\| PubMed ID: 19047050	2009
MDM2 is a novel E3 ligase for HIV-1 Vif. Retrovirology\| PubMed ID: 19128510	2009
[In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,919 clinical isolates obtained from 72 centers in 2007]. The Japanese journal of antibiotics\| PubMed ID: 19860322	2009
[Evaluation of the factor which has an influence on red blood cell deformability in patients with end-stage renal disease]. Rinsho byori. The Japanese journal of clinical pathology\| PubMed ID: 19928493	2009
Key odor components responsible for the impact on olfactory sense during swine feces composting. Bioresource technology\| PubMed ID: 19962882	2010
Case of remitting seronegative symmetrical synovitis with pitting edema (RS3PE syndrome) showing dermatomyositis-like eruption. The Journal of dermatology\| PubMed ID: 20175831	2010
[Black esophagus due to acute necrotizing esophagitis: four case reports]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology\| PubMed ID: 21558743	2011
Olecranon bursa with Fusarium solani infection in an otherwise healthy patient. Mycoses\| PubMed ID: 21605189	2011
Wnt2 accelerates cardiac myocyte differentiation from ES-cell derived mesodermal cells via non-canonical pathway. Journal of molecular and cellular cardiology\| PubMed ID: 22146296	2012
Adriamycin enhances proteasome-mediated generation of the proapoptotic processed form of MAGE-A4 in hepatoma cells. Oncology\| PubMed ID: 22212933	2011
The p53 mRNA-Mdm2 interaction controls Mdm2 nuclear trafficking and is required for p53 activation following DNA damage. Cancer cell\| PubMed ID: 22264786	2012
HTLV-I Tax regulates the cellular proliferation through the down-regulation of PIP3-phosphatase expressions via the NF-κB pathway. International journal of biochemistry and molecular biology\| PubMed ID: 22509484	2012
Treatment of the ventricular tachycardia with engraftment of pluripotent stem cells-derived cardiomyocytes. Journal of molecular and cellular cardiology\| PubMed ID: 22543248	2012
Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22711815	2012
Cold-inducible RNA-binding protein modulates circadian gene expression posttranscriptionally. Science (New York, N.Y.)\| PubMed ID: 22923437	2012
In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues. Scientific reports\| PubMed ID: 22962636	2012
Myocardial cell sheet therapy and cardiac function. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 23001836	2012
Human pentraxin 3 (PTX3) as a novel biomarker for the diagnosis of pulmonary arterial hypertension. PloS one\| PubMed ID: 23029266	2012
Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells. BMC biotechnology\| PubMed ID: 23046908	2012
[Myocardial regeneration with cell transplantation therapy]. Nihon Geka Gakkai zasshi\| PubMed ID: 23061366	2012
Report of the American Heart Association (AHA) Scientific Sessions 2012, Los Angeles. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 23238304	2013
Deleterious effect of the IL-23/IL-17A axis and γδT cells on left ventricular remodeling after myocardial infarction. Journal of the American Heart Association\| PubMed ID: 23316306	2012
Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1. Biochemical and biophysical research communications\| PubMed ID: 23376718	2013
Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis. Nature medicine\| PubMed ID: 24097189	2013
Hypothermia protects against fulminant hepatitis in mice by reducing reactive oxygen species production. Digestive diseases (Basel, Switzerland)\| PubMed ID: 24281018	2013
(18)F-FDG-PET CT findings in a patient with early-phase cardiac sarcoidosis. Internal medicine (Tokyo, Japan)\| PubMed ID: 24292764	2013
Tumor necrosis factor and transforming growth factor β regulate clock genes by controlling the expression of the cold inducible RNA-binding protein (CIRBP). The Journal of biological chemistry\| PubMed ID: 24337574	2014
[Evaluation of conversion gastrectomy for treatment of Stage IV advanced gastric cancer]. Gan to kagaku ryoho. Cancer & chemotherapy\| PubMed ID: 24393866	2013
[A case of jejnal cancer who was controlled peritoneal metastasis, successfully by combination therapy with docetaxel and S-1]. Gan to kagaku ryoho. Cancer & chemotherapy\| PubMed ID: 24393899	2013
[Surgical resection of multiple liver metastases of rectal neuroendocrine tumors]. Gan to kagaku ryoho. Cancer & chemotherapy\| PubMed ID: 24393940	2013
Generation and characterization of functional cardiomyocytes derived from human T cell-derived induced pluripotent stem cells. PloS one\| PubMed ID: 24465630	2014
Future prospects for regenerated heart using induced pluripotent stem cells. Journal of pharmacological sciences\| PubMed ID: 24739283	2014
Cardiac magnetic resonance imaging in giant cell myocarditis: intriguing associations with clinical and pathological features. Circulation\| PubMed ID: 24778123	2014
Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions. PloS one\| PubMed ID: 24824994	2014
Expression of the oncoprotein gankyrin and phosphorylated retinoblastoma protein in human testis and testicular germ cell tumor. International journal of urology : official journal of the Japanese Urological Association\| PubMed ID: 24861729	2014
Stress response protein cirp links inflammation and tumorigenesis in colitis-associated cancer. Cancer research\| PubMed ID: 25187386	2014
A massive suspension culture system with metabolic purification for human pluripotent stem cell-derived cardiomyocytes. Stem cells translational medicine\| PubMed ID: 25355733	2014
Involvement of heat shock protein a4/apg-2 in refractory inflammatory bowel disease. Inflammatory bowel diseases\| PubMed ID: 25437815	2015
Cold-inducible RNA-binding protein promotes the development of liver cancer. Cancer science\| PubMed ID: 25611373	2015
Heat shock protein A4 controls cell migration and gastric ulcer healing. Digestive diseases and sciences\| PubMed ID: 25655005	2015
Three-dimensional cardiac cine imaging using the kat ARC acceleration: Initial experience in clinical adult patients at 3T. Magnetic resonance imaging\| PubMed ID: 25936683	2015
Dual phosphodiesterase type 5 inhibitor therapy for refractory pulmonary arterial hypertension: a pilot study. BMC pulmonary medicine\| PubMed ID: 25971443	2015
A case of lymphomatoid gastropathy: a self-limited pseudomalignant natural killer (NK)-cell proliferative disease mimicking NK/T-cell lymphomas. Clinical journal of gastroenterology\| PubMed ID: 26181731	2013
Gelatin Hydrogel Enhances the Engraftment of Transplanted Cardiomyocytes and Angiogenesis to Ameliorate Cardiac Function after Myocardial Infarction. PloS one\| PubMed ID: 26186362	2015
The Prevalence of Clinically Significant Ischemia in Patients Undergoing Percutaneous Coronary Intervention: A Report from the Multicenter Registry. PloS one\| PubMed ID: 26231033	2015