Barry Gold

Department of Pharmaceutical Sciences, University of Pittsburgh

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2015

Other Publications

Article	Year
Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes. Cancer chemotherapy and pharmacology\| PubMed ID: 11935214	2002
Influences of base excision repair defects on the lethality and mutagenicity induced by Me-lex, a sequence-selective N3-adenine methylating agent. The Journal of biological chemistry\| PubMed ID: 12042310	2002
Structure of a tethered cationic 3-aminopropyl chain incorporated into an oligodeoxynucleotide: evidence for 3'-orientation in the major groove accompanied by DNA bending. Journal of the American Chemical Society\| PubMed ID: 12121096	2002
Thermodynamic and hydration effects for the incorporation of a cationic 3-aminopropyl chain into DNA. Nucleic acids research\| PubMed ID: 12136099	2002
Bites of venomous snakes. The New England journal of medicine\| PubMed ID: 12151473	2002
Effect of cationic charge localization on DNA structure. Biopolymers\| PubMed ID: 12228922	2002
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor. Molecular pharmacology\| PubMed ID: 12488552	2003
Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes. DNA repair\| PubMed ID: 12509290	2002
Design of triple helix forming C-glycoside molecules. Journal of the American Chemical Society\| PubMed ID: 12590536	2003
Resolution of compartment syndrome after rattlesnake envenomation utilizing non-invasive measures. The Journal of emergency medicine\| PubMed ID: 12676299	2003
Evidence in Escherichia coli that N3-methyladenine lesions and cytotoxicity induced by a minor groove binding methyl sulfonate ester can be modulated in vivo by netropsin. Biochemistry\| PubMed ID: 14580207	2003
DNA damage and cytotoxicity induced by minor groove binding methyl sulfonate esters. Biochemistry\| PubMed ID: 14640700	2003
The biological effects of N3-methyladenine. Journal of cellular biochemistry\| PubMed ID: 14743385	2004
Triple helix forming TRIPside molecules that target mixed purine/pyrimidine DNA sequences. Biochemistry\| PubMed ID: 14769020	2004
Refractory thrombocytopenia despite treatment for rattlesnake envenomation. The New England journal of medicine\| PubMed ID: 15115843	2004
Nucleotide excision repair defect influences lethality and mutagenicity induced by Me-lex, a sequence-selective N3-adenine methylating agent in the absence of base excision repair. Biochemistry\| PubMed ID: 15134433	2004
The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. DNA repair\| PubMed ID: 15135730	2004
North American snake envenomation: diagnosis, treatment, and management. Emergency medicine clinics of North America\| PubMed ID: 15163575	2004
Ecology. Ecology for a crowded planet. Science (New York, N.Y.)\| PubMed ID: 15166349	2004
N3-methyladenine induces early poly(ADP-ribosylation), reduction of nuclear factor-kappa B DNA binding ability, and nuclear up-regulation of telomerase activity. Molecular pharmacology\| PubMed ID: 15548765	2005
Structure of B-DNA with cations tethered in the major groove. Biochemistry\| PubMed ID: 15895989	2005
Molecular recognition via triplex formation of mixed purine/pyrimidine DNA sequences using oligoTRIPs. Journal of the American Chemical Society\| PubMed ID: 16144414	2005
Incorporation of cationic chains in the Dickerson-Drew dodecamer: correlation of energetics, structure, and ion and water binding. Biochemistry\| PubMed ID: 16156670	2005
Synthesis of C-nucleosides designed to participate in triplex formation with native DNA: specific recognition of an A:T base pair in DNA. The Journal of organic chemistry\| PubMed ID: 16238307	2005
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 16288862	2005
The effect of 3-methyladenine DNA glycosylase-mediated DNA repair on the induction of toxicity and diabetes by the beta-cell toxicant streptozotocin. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 17098815	2007
A review of the role of the sequence-dependent electrostatic landscape in DNA alkylation patterns. Chemical research in toxicology\| PubMed ID: 17112226	2006
Human glioma cell sensitivity to the sequence-specific alkylating agent methyl-lexitropsin. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17255284	2007
A study of 7-deaza-2'-deoxyguanosine 2'-deoxycytidine base pairing in DNA. Nucleic acids research\| PubMed ID: 17855404	2007
Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent. DNA repair\| PubMed ID: 18182332	2008
A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' ... Biochemistry\| PubMed ID: 18549246	2008
Enhancing the engagement of U.S. private foundations with conservation science. Conservation biology : the journal of the Society for Conservation Biology\| PubMed ID: 18847442	2008
A facile synthetic approach to 7-deazaguanine nucleosides via a Boc protection strategy. Organic letters\| PubMed ID: 19422208	2009
Introduction of cationic charge into DNA near the major groove edge of a guanine x cytosine base pair: characterization of oligodeoxynucleotides substituted with 7-aminomethyl-7-deaza-2'-deo... Journal of the American Chemical Society\| PubMed ID: 19663509	2009
High frequency of genomic deletions induced by Me-lex, a sequence selective N3-adenine methylating agent, at the Hprt locus in Chinese hamster ovary cells. Mutation research\| PubMed ID: 19729030	2009
Mutagenicity of N3-methyladenine: a multi-translesion polymerase affair. Mutation research\| PubMed ID: 19874831	2010
Thermodynamic characterization of DNA with 3-deazaadenine and 3-methyl-3-deazaadenine substitutions: the effect of placing a hydrophobic group in the minor groove of DNA. The journal of physical chemistry. B\| PubMed ID: 20469878	2010
XRCC1 deficiency influences the cytotoxicity and the genomic instability induced by Me-lex, a specific inducer of N3-methyladenine. DNA repair\| PubMed ID: 20471330	2010
Methadone-induced torsade de pointes. The American journal of emergency medicine\| PubMed ID: 20674223	2011
An unprecedented nucleic acid capture mechanism for excision of DNA damage. Nature\| PubMed ID: 20927102	2010
Effect of n3-methyladenine and an isosteric stable analogue on DNA polymerization. Journal of nucleic acids\| PubMed ID: 20936169	2010
Characterization of DNA with an 8-oxoguanine modification. Nucleic acids research\| PubMed ID: 21572101	2011
3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro. DNA repair\| PubMed ID: 21676659	2011
Altering the electrostatic potential in the major groove: thermodynamic and structural characterization of 7-deaza-2'-deoxyadenosine:dT base pairing in DNA. The journal of physical chemistry. B\| PubMed ID: 22059929	2011
Thermodynamic signature of DNA damage: characterization of DNA with a 5-hydroxy-2'-deoxycytidine·2'-deoxyguanosine base pair. Biochemistry\| PubMed ID: 22332945	2012
Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs. Future medicinal chemistry\| PubMed ID: 22709253	2012
Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitors. Biochemistry\| PubMed ID: 22788932	2012
Synthesis and characterization of DNA minor groove binding alkylating agents. Chemical research in toxicology\| PubMed ID: 23234400	2013
Drug resistance: the problem that keeps on giving. Future medicinal chemistry\| PubMed ID: 23734679	2013
Forward: combating resistance: infectious diseases. Future medicinal chemistry\| PubMed ID: 23859196	2013
Site-specific stabilization of DNA by a tethered major groove amine, 7-aminomethyl-7-deaza-2'-deoxyguanosine. Biochemistry\| PubMed ID: 24131376	2013
Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: clarifying the role of N3-methyladenine. Mutation research\| PubMed ID: 24211855	2014
Looking for Waldo: a potential thermodynamic signature to DNA damage. Accounts of chemical research\| PubMed ID: 24702131	2014
T-cells enhance stem cell mutagenesis in the mouse colon. Mutation research\| PubMed ID: 25770826	2015
Design and activity of AP endonuclease-1 inhibitors. Journal of chemical biology\| PubMed ID: 26101550	2015
Colon carcinogenesis in wild type and immune compromised mice after treatment with azoxymethane, and azoxymethane with dextran sodium sulfate. Molecular carcinogenesis\| PubMed ID: 26153082	2015