Rupert Handgretinger

Deptartment of Hematology and Oncology, Children's University Hospital Tübingen

Affiliated withChildren's University Hospital Tübingen

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2015

Other Publications

Article	Year
Alpha-CD25 antibody treatment in a child with hemophagocytic lymphohistiocytosis. Medical and pediatric oncology\| PubMed ID: 11813188	2002
CD34 stem cell dose and development of extensive chronic graft-versus-host disease. Blood\| PubMed ID: 12014372	2002
Gene therapy for severe combined immunodeficiency disease. The New England journal of medicine\| PubMed ID: 12192024	2002
Summary of symposium: the future of stem cell transplantation for sickle cell disease. Journal of pediatric hematology/oncology\| PubMed ID: 12368684	2002
Transplantation of highly purified CD34+ progenitor cells from unrelated donors in pediatric leukemia. Blood\| PubMed ID: 12393439	2003
Identification of a novel class of human adherent CD34- stem cells that give rise to SCID-repopulating cells. Blood\| PubMed ID: 12393715	2003
Bone marrow-derived factors support growth of N-type, but not of melanocytic neuroblastoma cells. Anticancer research\| PubMed ID: 12553074	2002
Megadose transplantation of highly purified haploidentical stem cells: current results and future prospects. Pediatric transplantation\| PubMed ID: 12603693	2003
Receptor activator of nuclear factor kappaB ligand plays a nonredundant role in doxorubicin-induced apoptosis. Cancer research\| PubMed ID: 12702561	2003
Biology and plasticity of CD133+ hematopoietic stem cells. Annals of the New York Academy of Sciences\| PubMed ID: 12799292	2003
T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell-depleted HLA-non-identical paediatric bone marrow transplantation. British journal of haematology\| PubMed ID: 14531915	2003
Etiology and outcome of graft failure in pediatric hematopoietic stem cell transplant recipients. Journal of pediatric hematology/oncology\| PubMed ID: 14663279	2003
Possible allogeneic graft-versus-tumor effect in childhood melanoma. Journal of pediatric hematology/oncology\| PubMed ID: 14663285	2003
Transplantation of a combination of CD133+ and CD34+ selected progenitor cells from alternative donors. British journal of haematology\| PubMed ID: 14675410	2004
Determinants of antileukemia effects of allogeneic NK cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14688377	2004
Malignant infantile osteopetrosis and primary pulmonary hypertension: a new combination? Pediatric blood & cancer\| PubMed ID: 14752886	2004
Chimeric CD19 antibody mediates cytotoxic activity against leukemic blasts with effector cells from pediatric patients who received T-cell-depleted allografts. Blood\| PubMed ID: 14764538	2004
Successful treatment of primary refractory acute myeloid leukemia with megadose stem cell transplantation, bone marrow boost and reduced intensity conditioning avoiding chronic graft vs. hos... Pediatric transplantation\| PubMed ID: 14870901	2003
Cytotoxic activity of natural killer cells lacking killer-inhibitory receptors for self-HLA class I molecules against autologous hematopoietic stem cells in healthy individuals. Experimental and molecular pathology\| PubMed ID: 15010286	2004
Transplantation of highly purified CD34+ progenitor cells from alternative donors in children with refractory severe aplastic anaemia. British journal of haematology\| PubMed ID: 15015969	2004
Increasing mixed chimerism is an important prognostic factor for unfavorable outcome in children with acute lymphoblastic leukemia after allogeneic stem-cell transplantation: possible role f... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15117992	2004
Levels of total fungus and Aspergillus on a pediatric hematopoietic stem cell transplant unit. Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses\| PubMed ID: 15125550	2004
Human CD4+CD25+ regulatory T cells share equally complex and comparable repertoires with CD4+CD25- counterparts. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15128798	2004
Haploidentical transplantation for acute lymphoblastic leukemia in childhood. Blood reviews\| PubMed ID: 15183902	2004
Impaired T-cell activation and cytokine productivity after transplantation of positively selected CD34+ allogeneic hematopoietic stem cells. The hematology journal : the official journal of the European Haematology Association / EHA\| PubMed ID: 15297850	2004
Consolidation treatment with chimeric anti-GD2-antibody ch14.18 in children older than 1 year with metastatic neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15337804	2004
Prediction of T-cell reconstitution by assessment of T-cell receptor excision circle before allogeneic hematopoietic stem cell transplantation in pediatric patients. Blood\| PubMed ID: 15358630	2005
Phenotype and function of human natural killer cells purified by using a clinical-scale immunomagnetic method. Cancer immunology, immunotherapy : CII\| PubMed ID: 15449041	2005
Long-term outcome after haploidentical stem cell transplantation in children. Blood cells, molecules & diseases\| PubMed ID: 15528145	2004
Human gammadelta T cells from G-CSF-mobilized donors retain strong tumoricidal activity and produce immunomodulatory cytokines after clinical-scale isolation. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 15614047	2005
Graft-versus-Ewing sarcoma effect and long-term remission induced by haploidentical stem-cell transplantation in a patient with relapse of metastatic disease. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15625381	2005
Detection of adenovirus-specific T cells in children with adenovirus infection after allogeneic stem cell transplantation. British journal of haematology\| PubMed ID: 15686459	2005
Cytotoxic minor histocompatibility antigen HA-1-specific CD8+ effector memory T cells: artificial APCs pave the way for clinical application by potent primary in vitro induction. Blood\| PubMed ID: 15731181	2005
Experiences with haploidentical stem cell transplantation in children with acute lymphoblastic leukemia. Pathologie-biologie\| PubMed ID: 15781375	2005
Allogeneic graft-versus-hepatoblastoma effect. Pediatric blood & cancer\| PubMed ID: 15806543	2006
Brain parenchymal damage after haematopoietic stem cell transplantation for severe sickle cell disease. British journal of haematology\| PubMed ID: 15877739	2005
Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15879151	2005
Comparison of killer Ig-like receptor genotyping and phenotyping for selection of allogeneic blood stem cell donors. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15879158	2005
Outcome of hematopoietic stem cell transplantation for pediatric patients with therapy-related acute myeloid leukemia or myelodysplastic syndrome. Pediatric blood & cancer\| PubMed ID: 16155933	2006
Hemolytic uremic syndrome after bone marrow transplantation: clinical characteristics and outcome in children. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 16275594	2005
Combination immunotherapy with clinical-scale enriched human gammadelta T cells, hu14.18 antibody, and the immunocytokine Fc-IL7 in disseminated neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16322312	2005
EBV lymphoproliferative disease of host origin after haploidentical stem cell transplantation. Pediatric blood & cancer\| PubMed ID: 16421900	2007
KIR-incompatible hematopoietic-cell transplantation for poor prognosis infant acute lymphoblastic leukemia. Blood\| PubMed ID: 16434496	2006
The role of graft-versus-host disease in the inhibition of normal B-lymphopoiesis and leukemic control of B-lineage acute lymphocytic leukemia after allogeneic stem cell transplantation. Haematologica\| PubMed ID: 16531250	2006
Cidofovir for the treatment of adenoviral infection in pediatric hematopoietic stem cell transplant patients. Transplantation\| PubMed ID: 16732176	2006
Outcome of allogeneic stem cell transplantation in children with non-malignant diseases. Haematologica\| PubMed ID: 16769581	2006
Safe adoptive transfer of virus-specific T-cell immunity for the treatment of systemic adenovirus infection after allogeneic stem cell transplantation. British journal of haematology\| PubMed ID: 16803570	2006
Pitfalls in detection of contaminating neuroblastoma cells by tyrosine hydroxylase RT-PCR due to catecholamine-producing hematopoietic cells. Anticancer research\| PubMed ID: 16827147	2006
Efficient and reproducible large-scale isolation of human CD4+ CD25+ regulatory T cells with potent suppressor activity. Journal of immunological methods\| PubMed ID: 16887141	2006
Diagnostic challenge in recurrent skin rash after autologous bone marrow transplantation. Journal of pediatric hematology/oncology\| PubMed ID: 16912592	2006
Immune reconstitution after purified autologous and allogeneic blood stem cell transplantation compared with unmanipulated bone marrow transplantation in children. British journal of haematology\| PubMed ID: 16925797	2006
Increased alpha2,6-sialylation of surface proteins on tolerogenic, immature dendritic cells and regulatory T cells. Experimental hematology\| PubMed ID: 16939814	2006
In vitro analysis of multipotent mesenchymal stromal cells as potential cellular therapeutics in neurometabolic diseases in pediatric patients. Experimental hematology\| PubMed ID: 16982334	2006
Rapid immune reconstitution after a reduced-intensity conditioning regimen and a CD3-depleted haploidentical stem cell graft for paediatric refractory haematological malignancies. British journal of haematology\| PubMed ID: 17010105	2006
Selection of stem cells by using antibodies that target different CD34 epitopes yields different patterns of T-cell differentiation. Stem cells (Dayton, Ohio)\| PubMed ID: 17023516	2007
Haploidentical allogeneic hematopoietic cell transplantation in adults with reduced-intensity conditioning and CD3/CD19 depletion: fast engraftment and low toxicity. Experimental hematology\| PubMed ID: 17157172	2006
Adenovirus infection after allogeneic stem cell transplantation. Leukemia & lymphoma\| PubMed ID: 17325884	2007
Feasibility and outcome of reduced-intensity conditioning in haploidentical transplantation. Annals of the New York Academy of Sciences\| PubMed ID: 17442774	2007
Human multipotent mesenchymal stromal cells inhibit proliferation of PBMCs independently of IFNgammaR1 signaling and IDO expression. Blood\| PubMed ID: 17522338	2007
Intensity of HLA class I expression and KIR-mismatch determine NK-cell mediated lysis of leukaemic blasts from children with acute lymphatic leukaemia. British journal of haematology\| PubMed ID: 17555452	2007
A novel approach for the analysis of T-cell reconstitution by using a T-cell receptor beta-based oligonucleotide microarray in hematopoietic stem cell transplantation. Experimental hematology\| PubMed ID: 17577931	2007
Diagnostic yield of bronchoalveolar lavage is low in allogeneic hematopoietic stem cell recipients receiving immunosuppressive therapy or with acute graft-versus-host disease: the St. Jude e... Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 17580261	2007
Beyond the FACS. Stem cells (Dayton, Ohio)\| PubMed ID: 17656640	2007
Immunosuppressive total lymphoid irradiation-based reconditioning regimens enable engraftment after graft rejection or graft failure in patients treated with allogeneic hematopoietic stem ce... International journal of radiation oncology, biology, physics\| PubMed ID: 17869449	2008
Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: an update. Blood cells, molecules & diseases\| PubMed ID: 17869547	2008
Application of multipotent mesenchymal stromal cells in pediatric patients following allogeneic stem cell transplantation. Blood cells, molecules & diseases\| PubMed ID: 17869550	2008
Retransplantation with stem cells from mismatched related donors after graft rejection in pediatric patients. Blood cells, molecules & diseases\| PubMed ID: 17884640	2008
WT1 protein expression in childhood acute leukemia. American journal of hematology\| PubMed ID: 18161786	2008
Indications and donor selections for allogeneic stem cell transplantation in children with hematologic malignancies. Pediatric clinics of North America\| PubMed ID: 18242316	2008
Five donors-one recipient: modeling a mosaic of granulocytes, natural killer and T cells from cord-blood and third-party donors. Nature clinical practice. Oncology\| PubMed ID: 18364724	2008
WT1 protein expression in slowly proliferating myeloid leukemic cell lines is scarce throughout the cell cycle with a minimum in G0/G1 phase. Leukemia research\| PubMed ID: 18457871	2008
Molecular monitoring of immune reconstitution after haploidentical stem cell transplantation. Current stem cell research & therapy\| PubMed ID: 18473872	2008
Leucoencephalopathy, transverse myelopathy, and peripheral neuropathy in association with glutamic acid decarboxylase-65 (GAD) antibodies in children with cancer. Journal of child neurology\| PubMed ID: 18474930	2008
Clinical grade generation of hexon-specific T cells for adoptive T-cell transfer as a treatment of adenovirus infection after allogeneic stem cell transplantation. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 18481389	2008
Mesenchymal stromal cells: a novel treatment option for steroid-induced avascular osteonecrosis. The Israel Medical Association journal : IMAJ\| PubMed ID: 18494240	2008
Immune response of human propagated gammadelta-T-cells to neuroblastoma recommend the Vdelta1+ subset for gammadelta-T-cell-based immunotherapy. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 18832998	2008
Prognostic value of minimal residual disease quantification before allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia: the ALL-REZ BFM Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 19064980	2009
Total and active rabbit antithymocyte globulin (rATG;Thymoglobulin) pharmacokinetics in pediatric patients undergoing unrelated donor bone marrow transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 19167688	2009
Aberrant expression of the homeobox gene CDX2 in pediatric acute lymphoblastic leukemia. Blood\| PubMed ID: 19218548	2009
Dendritic cells: functional aspects of glycosylation and lectins. Human immunology\| PubMed ID: 19236902	2009
Clinical utility of computed tomography screening of chest, abdomen, and sinuses before hematopoietic stem cell transplantation: the St. Jude experience. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 19285637	2009
Uptake of mIBG and catecholamines in noradrenaline- and organic cation transporter-expressing cells: potential use of corticosterone for a preferred uptake in neuroblastoma- and pheochromocy... Nuclear medicine and biology\| PubMed ID: 19324274	2009
Highlights of the First International "Immunotherapy in Pediatric Oncology: Progress and Challenges" Meeting. Journal of pediatric hematology/oncology\| PubMed ID: 19346873	2009
Adult stem cells as an alternative source of multipotential (pluripotential) cells in regenerative medicine. Current stem cell research & therapy\| PubMed ID: 19442195	2009
Dynamics of the emergence of a human cytomegalovirus UL97 mutant strain conferring ganciclovir resistance in a pediatric stem-cell transplant recipient. The Journal of molecular diagnostics : JMD\| PubMed ID: 19477945	2009
Treating childhood acute lymphoblastic leukemia without cranial irradiation. The New England journal of medicine\| PubMed ID: 19553647	2009
Preservation of immune repertoire by selective depletion of haploidentical grafts. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 19941966	2010
Ex vivo detection of adenovirus specific CD4+ T-cell responses to HLA-DR-epitopes of the Hexon protein show a contracted specificity of T(HELPER) cells following stem cell transplantation. Virology\| PubMed ID: 19962170	2010
Chronic inflammatory bowel disease as key manifestation of atypical ARTEMIS deficiency. Journal of clinical immunology\| PubMed ID: 19967552	2010
Results and factors influencing outcome after fully haploidentical hematopoietic stem cell transplantation in children with very high-risk acute lymphoblastic leukemia: impact of center size... Blood\| PubMed ID: 20040760	2010
Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells. BMC cell biology\| PubMed ID: 20109207	2010
Reconstitution of natural killer cell receptors influences natural killer activity and relapse rate after haploidentical transplantation of T- and B-cell depleted grafts in children. Haematologica\| PubMed ID: 20145268	2010
Anti-GD(2) with an FC point mutation reduces complement fixation and decreases antibody-induced allodynia. Pain\| PubMed ID: 20171010	2010
Dendritic cell vaccination in an allogeneic stem cell recipient receiving a transplant from a human cytomegalovirus (HCMV)-seronegative donor: induction of a HCMV-specific T(helper) cell res... Cytotherapy\| PubMed ID: 20230226	2010
Immunotherapy in the context of hematopoietic stem cell transplantation: the emerging role of natural killer cells and mesenchymal stromal cells. Pediatric clinics of North America\| PubMed ID: 20307714	2010
High frequency of immature cells at diagnosis predicts high minimal residual disease level in childhood acute lymphoblastic leukemia. Leukemia research\| PubMed ID: 20378168	2010
H(2)O(2)-mediated cytotoxicity of pharmacologic ascorbate concentrations to neuroblastoma cells: potential role of lactate and ferritin. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 20511723	2010
Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation. Blood\| PubMed ID: 20625005	2010
Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells. Blood\| PubMed ID: 20644118	2010
Long-term human CD34+ stem cell-engrafted nonobese diabetic/SCID/IL-2R gamma(null) mice show impaired CD8+ T cell maintenance and a functional arrest of immature NK cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20668220	2010
Establishment of a rhabdomyosarcoma xenograft model in human-adapted mice. Oncology reports\| PubMed ID: 20811690	2010
Tumour stromal cells derived from paediatric malignancies display MSC-like properties and impair NK cell cytotoxicity. BMC cancer\| PubMed ID: 20858262	2010
Donor selection for AML: do the KIR. Blood\| PubMed ID: 20930082	2010
Point-counterpoint: haploidentical family donors versus cord blood transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 21195317	2011
High proportion of leukemic stem cells at diagnosis is correlated with unfavorable prognosis in childhood acute myeloid leukemia. Pediatric hematology and oncology\| PubMed ID: 21214408	2011
Expression of therapeutic proteins after delivery of chemically modified mRNA in mice. Nature biotechnology\| PubMed ID: 21217696	2011
Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy. BMC cancer\| PubMed ID: 21244693	2011
Long-term remission after first-line single-agent treatment with arsenic trioxide of relapsed acute promyelocytic leukemia in an 8-year-old boy. Pediatric hematology and oncology\| PubMed ID: 21345080	2011
Impaired tumor rejection by memory CD8 T cells in mice with NKG2D dysfunction. International journal of cancer. Journal international du cancer\| PubMed ID: 21607945	2012
High success rate of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia. Blood\| PubMed ID: 21613256	2011
CD155 is involved in NK-cell mediated lysis of human hepatoblastoma in vitro. Frontiers in bioscience (Elite edition)\| PubMed ID: 21622149	2011
Highlights of the second international conference on "Immunotherapy in Pediatric Oncology". Pediatric hematology and oncology\| PubMed ID: 21854215	2011
Natural killer cell activity influences outcome after T cell depleted stem cell transplantation from matched unrelated and haploidentical donors. Best practice & research. Clinical haematology\| PubMed ID: 21925093	2011
Long-term IL-2 therapy after transplantation of T cell depleted stem cells from alternative donors in children. Best practice & research. Clinical haematology\| PubMed ID: 21925097	2011
Comparison of different adjuvant radiotherapy approaches in childhood bladder/prostate rhabdomyosarcoma treated with conservative surgery. Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]\| PubMed ID: 22037652	2011
Extended hepatic resection in advanced hepatoblastoma. Frontiers in bioscience (Elite edition)\| PubMed ID: 22201886	2012
Haploidentical stem cell transplantation for children with high-risk leukemia. Pediatric blood & cancer\| PubMed ID: 22238059	2012
Surgical treatment of lung metastases in patients with embryonal pediatric solid tumors: an update. Seminars in pediatric surgery\| PubMed ID: 22248973	2012
New strategies for haploidentical transplantation. Pediatric research\| PubMed ID: 22278184	2012
Monocytes derived from humanized neonatal NOD/SCID/IL2Rγ(null) mice are phenotypically immature and exhibit functional impairments. Human immunology\| PubMed ID: 22330087	2012
Bacterial reprogramming of PBMCs impairs monocyte phagocytosis and modulates adaptive T cell responses. Journal of leukocyte biology\| PubMed ID: 22427683	2012
Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: a phase II study. Haematologica\| PubMed ID: 22491731	2012
Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy? Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 22508045	2012
Detectable minimal residual disease before hematopoietic cell transplantation is prognostic but does not preclude cure for children with very-high-risk leukemia. Blood\| PubMed ID: 22517895	2012
Surgical management of stem cell transplantation-related complications in children. Pediatric transplantation\| PubMed ID: 22584038	2012
Siglec-7 tetramers characterize B-cell subpopulations and leukemic blasts. European journal of immunology\| PubMed ID: 22585296	2012
Alternative donor HSCT in refractory acquired aplastic anemia: the time has come. Pediatric transplantation\| PubMed ID: 22646164	2012
Characterisation of the cell line HC-AFW1 derived from a pediatric hepatocellular carcinoma. PloS one\| PubMed ID: 22666492	2012
Caspofungin as antifungal prophylaxis in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation: a retrospective analysis. BMC infectious diseases\| PubMed ID: 22747637	2012
Immune reconstitution and strategies for rebuilding the immune system after haploidentical stem cell transplantation. Annals of the New York Academy of Sciences\| PubMed ID: 22901267	2012
Negative depletion of CD3(+) and TcRαβ(+) T cells. Current opinion in hematology\| PubMed ID: 22914586	2012
Suicidal T cells: a jump-start for the thymus. Blood\| PubMed ID: 22936734	2012
Analysis of posaconazole as oral antifungal prophylaxis in pediatric patients under 12 years of age following allogeneic stem cell transplantation. BMC infectious diseases\| PubMed ID: 23082876	2012
Induction of Thelper1-driven antiviral T-cell lines for adoptive immunotherapy is determined by differential expression of IFN-γ and T-cell activation markers. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 23090075	2012
CD133-Positive Hematopoietic Stem Cells: From Biology to Medicine. Advances in experimental medicine and biology\| PubMed ID: 23161078	2013
Adoptive transfer of epstein-barr virus (EBV) nuclear antigen 1-specific t cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem-cell transplantatio... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 23169501	2013
New approaches to graft engineering for haploidentical bone marrow transplantation. Seminars in oncology\| PubMed ID: 23206843	2012
Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling. Blood\| PubMed ID: 23223360	2013
Eradication of pulmonary aspergillosis in an adolescent patient undergoing three allogeneic stem cell transplantations for acute lymphoblastic leukemia. Case reports in transplantation\| PubMed ID: 23259137	2012
Flagellin induces myeloid-derived suppressor cells: implications for Pseudomonas aeruginosa infection in cystic fibrosis lung disease. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23277486	2013
Innate immune defense defines susceptibility of sarcoma cells to measles vaccine virus-based oncolysis. Journal of virology\| PubMed ID: 23302892	2013
T-helper-1-cell cytokines drive cancer into senescence. Nature\| PubMed ID: 23376950	2013
Treatment of liver transplant graft-versus-host disease with antibodies against tumor necrosis factor-α. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation\| PubMed ID: 23387543	2013
Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism. The Journal of clinical investigation\| PubMed ID: 23391720	2013
CAReful epitope selection matters. Blood\| PubMed ID: 23411729	2013
Influence of a mutation in IFN-γ receptor 2 (IFNGR2) in human cells on the generation of Th17 cells in memory T cells. Human immunology\| PubMed ID: 23459074	2013
One goal, different strategies--molecular and cellular approaches for the treatment of inherited skin fragility disorders. Experimental dermatology\| PubMed ID: 23489418	2013
Engraftment of low numbers of pediatric acute lymphoid and myeloid leukemias into NOD/SCID/IL2Rcγnull mice reflects individual leukemogenecity and highly correlates with clinical outcome. International journal of cancer. Journal international du cancer\| PubMed ID: 23526331	2013
Influence of Histone Deacetylase Inhibitors and DNA-Methyltransferase Inhibitors on the NK Cell-Mediated Lysis of Pediatric B-Lineage Leukemia. Frontiers in oncology\| PubMed ID: 23641363	2013
Depletion of T-cell receptor alpha/beta and CD19 positive cells from apheresis products with the CliniMACS device. Cytotherapy\| PubMed ID: 23993299	2013
Therapy response correlates with ALDH activity in ALDH low-positive childhood acute lymphoblastic leukemias. Pediatric hematology and oncology\| PubMed ID: 24308780	2014
Inadvertent intravenous administration of maternal breast milk in a six-week-old infant: a case report and review of the literature. BMC research notes\| PubMed ID: 24401324	2014
Arsenic trioxide inhibits tumor cell growth in malignant rhabdoid tumors in vitro and in vivo by targeting overexpressed Gli1. International journal of cancer. Journal international du cancer\| PubMed ID: 24420698	2014
Transplantation of CD3/CD19 depleted allografts from haploidentical family donors in paediatric leukaemia. British journal of haematology\| PubMed ID: 24588540	2014
Haploidentical stem cell transplantation in DOCK8 deficiency - Successful control of pre-existing severe viremia with a TCRaß/CD19-depleted graft and antiviral treatment. Clinical immunology (Orlando, Fla.)\| PubMed ID: 24667686	2014
Combined PET/MR: Where are we now? Summary report of the second international workshop on PET/MR imaging April 8-12, 2013, Tubingen, Germany. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 24668195	2014
In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient survival. Pigment cell & melanoma research\| PubMed ID: 24703331	2014
Phase I trial of a novel anti-GD2 monoclonal antibody, Hu14.18K322A, designed to decrease toxicity in children with refractory or recurrent neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 24711551	2014
Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab. Haematologica\| PubMed ID: 24727818	2014
KIR haplotype B donors but not KIR-ligand mismatch result in a reduced incidence of relapse after haploidentical transplantation using reduced intensity conditioning and CD3/CD19-depleted gr... Annals of hematology\| PubMed ID: 24771045	2014
Synthesis and biological effects of new hybrid compounds composed of benzylguanidines and the alkylating group of busulfan on neuroblastoma cells. Bioorganic & medicinal chemistry letters\| PubMed ID: 24814532	2014
HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders. Blood\| PubMed ID: 24869942	2014
A newborn with grouped facial skin lesions and subsequent seizures. BMC pediatrics\| PubMed ID: 24884686	2014
The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse. Haematologica\| PubMed ID: 24972766	2014
How an accidental discovery paved the way for the treatment of complicated infantile haemangiomas. Acta paediatrica (Oslo, Norway : 1992)\| PubMed ID: 25040099	2014
Will post-transplantation cell therapies for pediatric patients become standard of care? Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 25064748	2015
Haploidentical transplantation: the search for the best donor. Blood\| PubMed ID: 25104858	2014
Human leukocyte antigen DR surface expression on CD14+ monocytes during adverse events after hematopoietic stem cell transplantation. Annals of hematology\| PubMed ID: 25113134	2015
KIR B haplotype donors confer a reduced risk for relapse after haploidentical transplantation in children with ALL. Blood\| PubMed ID: 25115891	2014
Monocyte-induced development of Th17 cells and the release of S100 proteins are involved in the pathogenesis of graft-versus-host disease. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25187661	2014
Tumour volume reduction after neoadjuvant chemotherapy impacts outcome in localised embryonal rhabdomyosarcoma. Pediatric blood & cancer\| PubMed ID: 25263634	2015
Both mature KIR+ and immature KIR- NK cells control pediatric acute B-cell precursor leukemia in NOD.Cg-Prkdcscid IL2rgtmWjl/Sz mice. Blood\| PubMed ID: 25359989	2014
γδ T Cell-Mediated Antibody-Dependent Cellular Cytotoxicity with CD19 Antibodies Assessed by an Impedance-Based Label-Free Real-Time Cytotoxicity Assay. Frontiers in immunology\| PubMed ID: 25520723	2014
Phagocytic activity of monocytes, their subpopulations and granulocytes during post-transplant adverse events after hematopoietic stem cell transplantation. Immunobiology\| PubMed ID: 25541241	2015
Arabinoxylan rice bran (MGN-3/Biobran) enhances natural killer cell-mediated cytotoxicity against neuroblastoma in vitro and in vivo. Cytotherapy\| PubMed ID: 25541298	2015
Patterns of monocyte subpopulations and their surface expression of HLA-DR during adverse events after hematopoietic stem cell transplantation. Annals of hematology\| PubMed ID: 25544031	2015
A functional inflammasome activation assay differentiates patients with pathogenic NLRP3 mutations and symptomatic patients with low penetrance variants. Clinical immunology (Orlando, Fla.)\| PubMed ID: 25596455	2015
Adoptive T-cell therapy with hexon-specific Th1 cells as a treatment of refractory adenovirus infection after HSCT. Blood\| PubMed ID: 25617426	2015
Human Peripheral CD4(+) Vδ1(+) γδT Cells Can Develop into αβT Cells. Frontiers in immunology\| PubMed ID: 25709606	2014
Simultaneous Resection of High-risk Liver Tumors and Pulmonary Metastases in Children. Annals of surgery\| PubMed ID: 25719810	2015
Pathogenic fungi regulate immunity by inducing neutrophilic myeloid-derived suppressor cells. Cell host & microbe\| PubMed ID: 25771792	2015
High Local Concentrations of Intradermal MSCs Restore Skin Integrity and Facilitate Wound Healing in Dystrophic Epidermolysis Bullosa. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 25858020	2015
Chorein addiction in VPS13A overexpressing rhabdomyosarcoma cells. Oncotarget\| PubMed ID: 25871399	2015
In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency. Nature biotechnology\| PubMed ID: 25985262	2015
No association between the presence of killer-cell immunoglobulin-like receptor genes and susceptibility to childhood ALL. Blood\| PubMed ID: 25999446	2015
Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation. Oncoimmunology\| PubMed ID: 26140238	2015
Chronic graft-versus-host-disease in CD34(+)-humanized NSG mice is associated with human susceptibility HLA haplotypes for autoimmune disease. Journal of autoimmunity\| PubMed ID: 26143958	2015
Rapid generation of NY-ESO-1-specific CD4(+) THELPER1 cells for adoptive T-cell therapy. Oncoimmunology\| PubMed ID: 26155389	2015
Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma. Cancer biology & therapy\| PubMed ID: 26177922	2015
NKG2D Signaling Leads to NK Cell Mediated Lysis of Childhood AML. Journal of immunology research\| PubMed ID: 26236752	2015
Preemptive administration of human αβ T cell receptor-targeting monoclonal antibody GZ-αβTCR potently abrogates aggressive graft-versus-host disease in vivo. Annals of hematology\| PubMed ID: 26264693	2015
Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation. Haematologica\| PubMed ID: 26294725	2015
Cytokine serum levels during post-transplant adverse events in 61 pediatric patients after hematopoietic stem cell transplantation. BMC cancer\| PubMed ID: 26315105	2015
Enriched Bone Marrow Derived Disseminated Neuroblastoma Cells Can Be a Reliable Source for Gene Expression Studies-A Validation Study. PloS one\| PubMed ID: 26360775	2015
Posaconazole plasma concentration in pediatric patients receiving antifungal prophylaxis after allogeneic hematopoietic stem cell transplantation. Medical mycology\| PubMed ID: 26483433	2015
Hoechst 33342 Staining Identifies the Progenitor Side Population in NOD.Cg-PrkdcscidIL2rgtmWjl/Sz Mice Harboring Pediatric Leukemias. In vivo (Athens, Greece)\| PubMed ID: 26546522	2015
Modified mRNA as a new therapeutic option for pediatric respiratory diseases and hemoglobinopathies. Molecular and cellular pediatrics\| PubMed ID: 26589812	2015
Ferritin as an early marker of graft rejection after allogeneic hematopoietic stem cell transplantation in pediatric patients. Annals of hematology\| PubMed ID: 26611853	2015