Khaled Barakat

Li Ka Shing Institute for Virology, University of Alberta

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 40	2016

Other Publications

Article	Year
Easy tissue expansion of prelaminated mucosa-lined flaps for cheek reconstruction in a canine model. Plastic and reconstructive surgery\| PubMed ID: 11994602	2002
The effect of low-molecular-weight heparin in the survival of a rabbit congested skin flap. Plastic and reconstructive surgery\| PubMed ID: 11994604	2002
Design and pharmacology of N-[(3R)-1,2,3,4-tetrahydroisoquinolinium- 3-ylcarbonyl]-(1R)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1H-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (1... Journal of medicinal chemistry\| PubMed ID: 12361385	2002
Clinical outcome in cranioplasty: critical review in long-term follow-up. The Journal of craniofacial surgery\| PubMed ID: 12621283	2003
Evaluation of 45S5 bioactive glass combined as a bone substitute in the reconstruction of critical size calvarial defects in rabbits. The Journal of craniofacial surgery\| PubMed ID: 15699647	2005
Hypertelorism: the importance of three-dimensional imaging and trends in the surgical correction by facial bipartition. Plastic and reconstructive surgery\| PubMed ID: 15861056	2005
Discovery and activity of (1R,4S,6R)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-2-methyl-2-azabicyclo[2.2.2]octane-6... Bioorganic & medicinal chemistry letters\| PubMed ID: 15982875	2005
Melanocortin subtype 4 receptor agonists: structure-activity relationships about the 4-alkyl piperidine core. Bioorganic & medicinal chemistry letters\| PubMed ID: 17768046	2007
Melanotic neuroectodermal tumor of infancy: review of literature and case report. Journal of pediatric surgery\| PubMed ID: 18558161	2008
Characterization of an inhibitory dynamic pharmacophore for the ERCC1-XPA interaction using a combined molecular dynamics and virtual screening approach. Journal of molecular graphics & modelling\| PubMed ID: 19473860	2009
Electrostatic contributions to colchicine binding within tubulin isotypes. Electromagnetic biology and medicine\| PubMed ID: 20017626	2009
Ensemble-based virtual screening reveals dual-inhibitors for the p53-MDM2/MDMX interactions. Journal of molecular graphics & modelling\| PubMed ID: 20056466	2010
Discovery and characterization of the laulimalide-microtubule binding mode by mass shift perturbation mapping. Chemistry & biology\| PubMed ID: 20659685	2010
Relaxed complex scheme suggests novel inhibitors for the lyase activity of DNA polymerase beta. Journal of molecular graphics & modelling\| PubMed ID: 21194999	2011
Effects of temperature on the p53-DNA binding interactions and their dynamical behavior: comparing the wild type to the R248Q mutant. PloS one\| PubMed ID: 22110706	2011
Discovery of small molecule inhibitors that interact with γ-tubulin. Chemical biology & drug design\| PubMed ID: 22268380	2012
DNA polymerase beta (pol β) inhibitors: a comprehensive overview. Drug discovery today\| PubMed ID: 22561893	2012
DNA Repair Inhibitors: Our Last Disposal to Improve Cancer Therapy. Current topics in medicinal chemistry\| PubMed ID: 22690684	2012
Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia. PloS one\| PubMed ID: 22761654	2012
DNA repair inhibitors: the next major step to improve cancer therapy. Current topics in medicinal chemistry\| PubMed ID: 22794314	2012
Modeling the yew tree tubulin and a comparison of its interaction with paclitaxel to human tubulin. Pharmaceutical research\| PubMed ID: 22833053	2012
Virtual screening and biological evaluation of inhibitors targeting the XPA-ERCC1 interaction. PloS one\| PubMed ID: 23272099	2012
Small molecule inhibitors of ERCC1-XPF protein-protein interaction synergize alkylating agents in cancer cells. Molecular pharmacology\| PubMed ID: 23580445	2013
A computational model for overcoming drug resistance using selective dual-inhibitors for aurora kinase A and its T217D variant. Molecular pharmaceutics\| PubMed ID: 24094068	2013
Detailed computational study of the active site of the hepatitis C viral RNA polymerase to aid novel drug design. Journal of chemical information and modeling\| PubMed ID: 24116674	2013
Immunomodulatory Function of Interleukin 28B during primary infection with cytomegalovirus. The Journal of infectious diseases\| PubMed ID: 24620020	2014
A Refined Model of the HCV NS5A protein bound to daclatasvir explains drug-resistant mutations and activity against divergent genotypes. Journal of chemical information and modeling\| PubMed ID: 24730573	2015
Vaccine adjuvants--understanding molecular mechanisms to improve vaccines. Swiss medical weekly\| PubMed ID: 24844935	2014
A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity. Toxicology letters\| PubMed ID: 25127758	2014
Human structural proteome-wide characterization of Cyclosporine A targets. Bioinformatics (Oxford, England)\| PubMed ID: 25172926	2014
Thermoplastic vestibuloplasty: a novel technique for treatment of lip and cheek adhesion. Craniomaxillofacial trauma & reconstruction\| PubMed ID: 25383145	2014
IL-28B is a key regulator of B- and T-cell vaccine responses against influenza. PLoS pathogens\| PubMed ID: 25503988	2014
Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA. Drug discovery today\| PubMed ID: 25622780	2015
Human PD-1 binds differently to its human ligands: a comprehensive modeling study. Journal of molecular graphics & modelling\| PubMed ID: 25723350	2015
Discovery of Novel Peptidomimetics as Irreversible CHIKV NsP2 Protease Inhibitors Using Quantum Mechanical-Based Ligand Descriptors. Chemical biology & drug design\| PubMed ID: 26212366	2015
Entropy in bimolecular simulations: A comprehensive review of atomic fluctuations-based methods. Journal of molecular graphics & modelling\| PubMed ID: 26407139	2015
New design of nucleotide excision repair (NER) inhibitors for combination cancer therapy. Journal of molecular graphics & modelling\| PubMed ID: 26939044	2016