Kebin Liu

Department of Biochemistry and Molecular Biology, Medical College of Georgia

Affiliated withMedical College of Georgia augusta university Charlie Norwood Va Medical Center

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 21	2010
Publication title Cited by 83	2016

Other Publications

Article	Year
IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11972069	2002
IL-15 is a growth factor and an activator of CD8 memory T cells. Annals of the New York Academy of Sciences\| PubMed ID: 12538153	2002
Alterations in Fas expression are characteristic of, but not solely responsible for, enhanced metastatic competence. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12794124	2003
Coordinate regulation of IFN consensus sequence-binding protein and caspase-1 in the sensitization of human colon carcinoma cells to Fas-mediated apoptosis by IFN-gamma. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12794166	2003
Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12794167	2003
Exposure of human primary colon carcinoma cells to anti-Fas interactions influences the emergence of pre-existing Fas-resistant metastatic subpopulations. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14530339	2003
Cooperative disengagement of Fas and intercellular adhesion molecule-1 function in neoplastic cells confers enhanced colonization efficiency. Cancer research\| PubMed ID: 15705906	2005
Immune selection and emergence of aggressive tumor variants as negative consequences of Fas-mediated cytotoxicity and altered IFN-gamma-regulated gene expression. Cancer research\| PubMed ID: 15899830	2005
CTL adoptive immunotherapy concurrently mediates tumor regression and tumor escape. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16517705	2006
A2A adenosine receptor protects tumors from antitumor T cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16916931	2006
[Aromatic constituents in fresh leaves of Lingtou Dancong tea under Basilepta melanopus Lefevre stress]. Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban\| PubMed ID: 17269334	2006
Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells. Cancer research\| PubMed ID: 17409439	2007
Targeting lymphotoxin beta receptor with tumor-specific T lymphocytes for tumor regression. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17785576	2007
IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17878376	2007
Downregulation of IFN-gammaR in association with loss of Fas function is linked to tumor progression. International journal of cancer. Journal international du cancer\| PubMed ID: 17918178	2008
Host immunosurveillance controls tumor growth via IFN regulatory factor-8 dependent mechanisms. Cancer research\| PubMed ID: 17974984	2007
Effects of targeted Bcl-2 expression in mitochondria or endoplasmic reticulum on renal tubular cell apoptosis. American journal of physiology. Renal physiology\| PubMed ID: 18160625	2008
Expression of cyclic guanosine monophosphate-dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesis. Cancer\| PubMed ID: 18260092	2008
DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells. Molecular cancer research : MCR\| PubMed ID: 19074829	2008
The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity. American journal of physiology. Renal physiology\| PubMed ID: 19144690	2009
IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression. Cancer research\| PubMed ID: 19155307	2009
Interferon Regulatory Factor-8 Modulates the Development of Tumor-Induced CD11bGr-1 Myeloid Cells. Journal of cellular and molecular medicine\| PubMed ID: 19187118	2009
GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. Cancer research\| PubMed ID: 19276343	2009
Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse. Investigative ophthalmology & visual science\| PubMed ID: 19357353	2009
Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchanger. The Biochemical journal\| PubMed ID: 19715555	2009
Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression. Cancer research\| PubMed ID: 19920183	2009
Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract\| PubMed ID: 20033346	2010
Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury. The American journal of pathology\| PubMed ID: 20075199	2010
Interferon regulatory factor-8 modulates the development of tumour-induced CD11b+Gr-1+ myeloid cells. Journal of cellular and molecular medicine\| PubMed ID: 20196788	2009
TRAIL and doxorubicin combination induces proapoptotic and antiangiogenic effects in soft tissue sarcoma in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20406839	2010
Sigma receptor 1 modulates endoplasmic reticulum stress in retinal neurons. Investigative ophthalmology & visual science\| PubMed ID: 20811050	2011
Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery. Human molecular genetics\| PubMed ID: 20940144	2011
IFN-Î³ upregulates survivin and Ifi202 expression to induce survival and proliferation of tumor-specific T cells. PloS one\| PubMed ID: 21124930	2010
Role of apoptosis resistance in immune evasion and metastasis of colorectal cancer. World journal of gastrointestinal oncology\| PubMed ID: 21160903	2010
TNFÎ± cooperates with IFN-Î³ to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis. PloS one\| PubMed ID: 21264227	2011
IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemia. Cancer research\| PubMed ID: 21487040	2011
Cyclic 3',5'-guanosine monophosphate-dependent protein kinase inhibits colon cancer cell adaptation to hypoxia. Cancer\| PubMed ID: 21563174	2011
Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3. Cancer research\| PubMed ID: 21911457	2011
Cutting edge: IRF8 regulates Bax transcription in vivo in primary myeloid cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21949018	2011
Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22461695	2012
Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 22517765	2012
Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 22556146	2012
NF-κB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression. The Journal of biological chemistry\| PubMed ID: 22669972	2012
Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance. Cancer research\| PubMed ID: 22805310	2012
Lymphotoxin β receptor mediates caspase-dependent tumor cell apoptosis in vitro and tumor suppression in vivo despite induction of NF-κB activation. Carcinogenesis\| PubMed ID: 23349015	2013
Hmgb1-TLR4-IL-23-IL-17A axis promote ischemia-reperfusion injury in a cardiac transplantation model. Transplantation\| PubMed ID: 23677049	2013
Deregulation of Apoptotic Factors Bcl-xL and Bax Confers Apoptotic Resistance to Myeloid-derived Suppressor Cells and Contributes to Their Persistence in Cancer. The Journal of biological chemistry\| PubMed ID: 23677993	2013
Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis. The Journal of clinical investigation\| PubMed ID: 24091328	2013
Long pentraxin PTX3 attenuates ischemia reperfusion injury in a cardiac transplantation model. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 24112130	2014
Epigenetics and colorectal cancer pathogenesis. Cancers\| PubMed ID: 24216997	2013
GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology. Molecular and cellular biology\| PubMed ID: 24248597	2014
Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression. BMC cancer\| PubMed ID: 24422988	2014
Tubular p53 regulates multiple genes to mediate AKI. Journal of the American Society of Nephrology : JASN\| PubMed ID: 24700871	2014
Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis. Cancer research\| PubMed ID: 24780756	2014
IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25646302	2015
IFNγ Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer. Cancer immunology research\| PubMed ID: 25735954	2015
Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization. Nature communications\| PubMed ID: 25813085	2015
H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26136424	2015
B Cell-Intrinsic IDO1 Regulates Humoral Immunity to T Cell-Independent Antigens. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26216892	2015
Epigenetic Regulation of Apoptosis and Cell Cycle Regulatory Genes in Human Colon Carcinoma Cells. Genomics data\| PubMed ID: 26309812	2015
The NF-κB p65 and p50 homodimer cooperate with IRF8 to activate iNOS transcription. BMC cancer\| PubMed ID: 26497740	2015
NF-κB functions as a molecular link between tumor cells and Th1/Tc1 T cells in the tumor microenvironment to exert radiation-mediated tumor suppression. Oncotarget\| PubMed ID: 27014915	2016
5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation. Oncotarget\| PubMed ID: 27027355	2016
Antitumor activity of sulfated hyaluronic acid fragments in pre-clinical models of bladder cancer. Oncotarget\| PubMed ID: 27419371	2016
Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes. Scientific reports\| PubMed ID: 27487939	2016