Matthew Merritt

Advanced Imaging Research Center, University of Texas Southwestern Medical Center

Affiliated withUniversity of Texas Southwestern Medical Center

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2016

Other Publications

Article	Year
Noninvasive evaluation of liver metabolism by 2H and 13C NMR isotopomer analysis of human urine. Analytical biochemistry\| PubMed ID: 12531210	2003
Sources of plasma glucose by automated Bayesian analysis of 2H NMR spectra. Magnetic resonance in medicine\| PubMed ID: 14523948	2003
PARACEST agents: modulating MRI contrast via water proton exchange. Accounts of chemical research\| PubMed ID: 14567712	2003
Silencing of phosphonate-gadolinium magnetic resonance imaging contrast by hydroxyapatite binding. Investigative radiology\| PubMed ID: 14627892	2003
Glucose production, gluconeogenesis, and hepatic tricarboxylic acid cycle fluxes measured by nuclear magnetic resonance analysis of a single glucose derivative. Analytical biochemistry\| PubMed ID: 15051530	2004
Glucose production pathways by 2H and 13C NMR in patients with HIV-associated lipoatrophy. Magnetic resonance in medicine\| PubMed ID: 15065235	2004
Impaired tricarboxylic acid cycle activity in mouse livers lacking cytosolic phosphoenolpyruvate carboxykinase. The Journal of biological chemistry\| PubMed ID: 15347677	2004
Differing mechanisms of hepatic glucose overproduction in triiodothyronine-treated rats vs. Zucker diabetic fatty rats by NMR analysis of plasma glucose. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 15562253	2005
Effect of murine strain on metabolic pathways of glucose production after brief or prolonged fasting. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 15797985	2005
Numerical solution of the Bloch equations provides insights into the optimum design of PARACEST agents for MRI. Magnetic resonance in medicine\| PubMed ID: 15799055	2005
Comparison of [3,4-13C2]glucose to [6,6-2H2]glucose as a tracer for glucose turnover by nuclear magnetic resonance. Magnetic resonance in medicine\| PubMed ID: 15906303	2005
A new class of macrocyclic lanthanide complexes for cell labeling and magnetic resonance imaging applications. Journal of the American Chemical Society\| PubMed ID: 16287307	2005
Effects of insulin and cytosolic redox state on glucose production pathways in the isolated perfused mouse liver measured by integrated 2H and 13C NMR. The Biochemical journal\| PubMed ID: 16288601	2006
Adiabatic JHSQC for 13C isotopomer analysis. Magnetic resonance in chemistry : MRC\| PubMed ID: 16408316	2006
Novel 1H NMR approach to quantitative tissue oximetry using hexamethyldisiloxane. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 16506157	2006
Storage and oxidation of long-chain fatty acids in the C57/BL6 mouse heart as measured by NMR spectroscopy. FEBS letters\| PubMed ID: 16831433	2006
Linkage between cellular communications, energy utilization, and proliferation in metastatic neuroendocrine cancers. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16895983	2006
Hepatic UDP-glucose 13C isotopomers from [U-13C]glucose: a simple analysis by 13C NMR of urinary menthol glucuronide. Magnetic resonance in medicine\| PubMed ID: 17036288	2006
Benefits of perfusion preservation in canine hearts stored for short intervals. The Journal of surgical research\| PubMed ID: 17509270	2007
Hyperpolarized (89)Y offers the potential of direct imaging of metal ions in biological systems by magnetic resonance. Journal of the American Chemical Society\| PubMed ID: 17927188	2007
Dipolar cross-relaxation modulates signal amplitudes in the (1)H NMR spectrum of hyperpolarized [(13)C]formate. Journal of magnetic resonance (San Diego, Calif. : 1997)\| PubMed ID: 17945520	2007
Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18056642	2007
Perfusion preservation versus static preservation for cardiac transplantation: effects on myocardial function and metabolism. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 18187093	2008
Partial resistance to peroxisome proliferator-activated receptor-alpha agonists in ZDF rats is associated with defective hepatic mitochondrial metabolism. Diabetes\| PubMed ID: 18469201	2008
Sources of hepatic glucose production by 2H2O ingestion and Bayesian analysis of 2H glucuronide enrichment. Magnetic resonance in medicine\| PubMed ID: 18727053	2008
Alterations in hepatic glucose and energy metabolism as a result of calorie and carbohydrate restriction. Hepatology (Baltimore, Md.)\| PubMed ID: 18925642	2008
Inhibition of carbohydrate oxidation during the first minute of reperfusion after brief ischemia: NMR detection of hyperpolarized 13CO2 and H13CO3-. Magnetic resonance in medicine\| PubMed ID: 18956454	2008
Hyperpolarized 89Y complexes as pH sensitive NMR probes. Journal of the American Chemical Society\| PubMed ID: 20102196	2010
Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-13C]pyruvate. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 20207817	2010
The effect of 13C enrichment in the glassing matrix on dynamic nuclear polarization of [1-13C]pyruvate. Physics in medicine and biology\| PubMed ID: 21285486	2011
1H magic angle spinning magnetic resonance spectroscopy for monitoring machine-perfused canine donor heart preservation prior to transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 21429765	2011
DNP by thermal mixing under optimized conditions yields >60,000-fold enhancement of 89Y NMR signal. Journal of the American Chemical Society\| PubMed ID: 21539398	2011
T2 exchange agents: a new class of paramagnetic MRI contrast agent that shortens water T2 by chemical exchange rather than relaxation. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine\| PubMed ID: 21608031	2011
Could 13C MRI assist clinical decision-making for patients with heart disease? NMR in biomedicine\| PubMed ID: 21608058	2011
Glucose is an ineffective substrate for preservation of machine perfused donor hearts. The Journal of surgical research\| PubMed ID: 21816432	2012
BDPA: an efficient polarizing agent for fast dissolution dynamic nuclear polarization NMR spectroscopy. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 21919088	2011
Transfer of hyperpolarization from long T1 storage nuclei to short T1 neighbors using FLOPSY-8. Journal of magnetic resonance (San Diego, Calif. : 1997)\| PubMed ID: 21974998	2011
Production and NMR characterization of hyperpolarized (107,109)Ag complexes. Angewandte Chemie (International ed. in English)\| PubMed ID: 21998014	2012
Differences in regional myocardial perfusion, metabolism, MVO2, and edema after coronary sinus machine perfusion preservation of canine hearts. ASAIO journal (American Society for Artificial Internal Organs : 1992)\| PubMed ID: 22036719	2011
Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22065779	2011
Nanoparticle-based PARACEST agents: the quenching effect of silica nanoparticles on the CEST signal from surface-conjugated chelates. Contrast media & molecular imaging\| PubMed ID: 22344876	2012
Comparison of kinetic models for analysis of pyruvate-to-lactate exchange by hyperpolarized 13 C NMR. NMR in biomedicine\| PubMed ID: 22451442	2012
Impact of Gd3+ on DNP of [1-13C]pyruvate doped with trityl OX063, BDPA, or 4-oxo-TEMPO. The journal of physical chemistry. A\| PubMed ID: 22571288	2012
The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy. RSC advances\| PubMed ID: 23205273	2012
Dissolution DNP-NMR spectroscopy using galvinoxyl as a polarizing agent. Journal of magnetic resonance (San Diego, Calif. : 1997)\| PubMed ID: 23246650	2013
Influence of deuteration in the glassing matrix on 13C dynamic nuclear polarization. Physical chemistry chemical physics : PCCP\| PubMed ID: 23552448	2013
Electron spin resonance studies of trityl OX063 at a concentration optimal for DNP. Physical chemistry chemical physics : PCCP\| PubMed ID: 23676994	2013
Simultaneous steady-state and dynamic 13C NMR can differentiate alternative routes of pyruvate metabolism in living cancer cells. The Journal of biological chemistry\| PubMed ID: 24415759	2014
Metabolic characteristics of human hearts preserved for 12 hours by static storage, antegrade perfusion, or retrograde coronary sinus perfusion. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 24642559	2014
Development and performance of a 129-GHz dynamic nuclear polarizer in an ultra-wide bore superconducting magnet. Magma (New York, N.Y.)\| PubMed ID: 25120071	2015
Hyperpolarized 13C NMR detects rapid drug-induced changes in cardiac metabolism. Magnetic resonance in medicine\| PubMed ID: 25168480	2015
Propionate stimulates pyruvate oxidation in the presence of acetate. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 25320331	2014
Real-time detection of hepatic gluconeogenic and glycogenolytic states using hyperpolarized [2-13C]dihydroxyacetone. The Journal of biological chemistry\| PubMed ID: 25352600	2014
Hyperpolarized magnetic resonance as a sensitive detector of metabolic function. Biochemistry\| PubMed ID: 25369537	2014
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport. Molecular cell\| PubMed ID: 25458842	2014
Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs. Methods in enzymology\| PubMed ID: 26358902	2015
Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors. Cancer research\| PubMed ID: 26420214	2015
Production of hyperpolarized (13)CO2 from [1-(13)C]pyruvate in perfused liver does reflect total anaplerosis but is not a reliable biomarker of glucose production. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 26543443	2015
Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. The Journal of clinical investigation\| PubMed ID: 26571396	2015
Metabolism of hyperpolarized [1-(13) C]pyruvate through alternate pathways in rat liver. NMR in biomedicine\| PubMed ID: 26836042	2016
Multiband spectral-spatial RF excitation for hyperpolarized [2-(13) C]dihydroxyacetone (13) C-MR metabolism studies. Magnetic resonance in medicine\| PubMed ID: 27017966	2016
Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. The Journal of clinical investigation\| PubMed ID: 27035816	2016
A general chemical shift decomposition method for hyperpolarized (13) C metabolite magnetic resonance imaging. Magnetic resonance in chemistry : MRC\| PubMed ID: 27060361	2016